Standard name
Human Ortholog
Description Component of the mitotic spindle; binds to interpolar microtubules via its association with beta-tubulin (Tub2p); required for interpolar microtubules to provide an outward force on the spindle poles
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm 0.97 0.97 0.97 0.98 0.98 0.94 0.9 0.87 0.83 – 0.75 0.71 1.0 0.99 0.98 – 0.89 0.93 0.75 0.82 0.69 0.9 0.85 0.8
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 0 0 0.06 0.08 0 0.14 0.21 0.23 0.35 – 0.42 0.41 0 0 0 – 0.06 0 0.12 0.07 0.17 0 0 0.05
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 0 0 0 0 1 0 0 0 – 0 0 0 0 0 – 0 0 1 3 2 0 2 5
Bud 1 1 2 1 0 3 3 14 8 – 6 2 0 1 2 – 0 1 0 5 0 0 8 16
Bud Neck 1 0 2 1 3 2 11 13 2 – 0 1 0 0 0 – 1 0 0 3 2 1 0 2
Bud Site 0 0 0 0 0 1 0 0 0 – 1 1 0 0 0 – 0 0 – – – – – –
Cell Periphery 3 0 0 2 3 1 4 5 0 – 1 1 0 0 1 – 0 0 0 1 3 1 1 2
Cytoplasm 156 326 194 198 348 321 448 617 274 – 114 103 206 476 487 – 87 75 131 281 128 205 274 304
Endoplasmic Reticulum 0 2 0 0 0 0 0 0 0 – 0 1 0 1 2 – 3 3 1 0 2 0 0 1
Endosome 2 2 0 0 0 0 2 2 0 – 0 0 0 1 0 – 1 1 3 2 2 1 1 4
Golgi 1 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 1 0 2 0 0 0 0 0
Mitochondria 6 12 12 16 15 49 105 164 116 – 64 60 1 3 14 – 6 0 21 24 30 8 13 18
Nucleus 0 0 0 0 0 1 3 1 2 – 3 1 0 0 1 – 0 0 0 1 0 0 0 0
Nuclear Periphery 0 1 0 0 0 0 1 0 0 – 2 2 0 0 0 – 0 1 0 1 0 0 0 1
Nucleolus 0 0 0 0 0 0 2 0 0 – 0 1 0 0 0 – 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 1 1 0 – 1 0 0 0 0 – 2 0 0 0 0 0 0 0
SpindlePole 0 1 1 0 2 1 1 21 3 – 3 3 0 0 0 – 2 1 3 1 2 0 2 5
Vac/Vac Membrane 3 0 0 1 0 2 2 3 0 – 2 1 0 0 2 – 2 1 3 7 5 2 7 8
Unique Cell Count 161 336 199 202 354 343 500 708 331 153 146 207 479 496 98 81 175 344 187 228 321 382
Labelled Cell Count 174 345 211 219 371 382 583 841 405 197 177 207 482 509 105 84 175 344 187 228 321 382


Ambiguous, SpindlePole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.1 3.3 3.1 2.9 3.3 2.9 2.8 2.9 2.5 – 2.8 2.5 4.2 3.9 3.6 4.6 5.5 5.4 3.9 3.7 4.3
Std Deviation (1e-4) 0.8 1.1 1.2 1.4 1.6 1.2 1.4 1.4 1.2 – 1.8 1.6 1.7 1.3 1.7 1.4 2.5 2.1 1.1 1.2 1.5
Intensity Change (Log2) – – – -0.1 0.08 -0.11 -0.13 -0.1 -0.3 – -0.15 -0.29 0.43 0.34 0.2 0.57 0.82 0.79 0.32 0.25 0.47

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.6149 1.3237 0.9341 0.4939 0.8417 1.0797 0.0671 0.3929 0.5799 -0.025 0.0664 0.3414 -0.1619 -0.2567 -0.2901 -0.1079 -0.2323 -0.2701
Actin 0.0445 0.0003 0.0136 0.0003 0.0079 0.0084 0.0095 0.0002 0.0022 0.0001 0.0327 0.0004 0.0088 0.0018 0.0142 0.0009 0.0005 0.0104
Bud 0.0018 0.001 0.0017 0.0001 0.0016 0.0004 0.0004 0.0016 0.0003 0 0.0006 0.0006 0.0014 0.0002 0.0019 0.0001 0 0.0002
Bud Neck 0.0195 0.0005 0.0028 0.0007 0.001 0.007 0.0005 0.0022 0.0015 0.0005 0.0098 0.0115 0.0011 0.0024 0.0013 0.0005 0.0002 0.0007
Bud Periphery 0.005 0.0031 0.0049 0.0002 0.0034 0.0035 0.0008 0.0048 0.0009 0 0.0007 0.0007 0.0017 0.0002 0.0025 0.0001 0 0.0003
Bud Site 0.0191 0.0079 0.013 0.0001 0.0089 0.0032 0.0029 0.0056 0.0102 0 0.0104 0.0004 0.0161 0.036 0.003 0.0001 0 0.0001
Cell Periphery 0.0021 0.0006 0.0011 0.0001 0.0013 0.0006 0.0003 0.0003 0.0001 0 0.0002 0.0001 0.0003 0.0003 0.0007 0 0 0
Cytoplasm 0.0473 0.0689 0.0892 0.0771 0.0753 0.1358 0.0388 0.0747 0.0487 0.047 0.1241 0.1794 0.0328 0.0697 0.0315 0.0439 0.0323 0.0757
Cytoplasmic Foci 0.0457 0.0198 0.0454 0.0737 0.0951 0.0337 0.0622 0.0262 0.0974 0.0309 0.031 0.0159 0.0362 0.0587 0.0722 0.0539 0.0222 0.0309
Eisosomes 0.0019 0.0002 0.0008 0.0001 0.0012 0.0003 0.0003 0.0001 0.0001 0 0.0002 0 0.0008 0.0004 0.0005 0.0003 0.0001 0.0002
Endoplasmic Reticulum 0.0156 0.0009 0.0022 0.0005 0.0014 0.0018 0.0186 0.0006 0.0007 0.0003 0.0107 0.001 0.0051 0.0005 0.0018 0.0007 0.0002 0.0006
Endosome 0.0327 0.0025 0.0069 0.0027 0.0347 0.0041 0.0309 0.0036 0.0045 0.0093 0.0197 0.0029 0.0302 0.0033 0.0076 0.011 0.0004 0.0019
Golgi 0.0125 0.0001 0.0045 0.0002 0.0076 0.002 0.0125 0.0006 0.0005 0.0004 0.0044 0.0003 0.0198 0.0007 0.0023 0.0141 0.0001 0.0012
Lipid Particles 0.0207 0.0008 0.0042 0.0005 0.0141 0.0021 0.0291 0.0063 0.0018 0.0131 0.0015 0.0008 0.0083 0.0011 0.008 0.0011 0.0003 0.0008
Mitochondria 0.0184 0.0003 0.0147 0.0002 0.0566 0.0034 0.0072 0.0031 0.0009 0.0001 0.0009 0.0012 0.0025 0.0314 0.0041 0.0064 0 0.0006
None 0.6386 0.8745 0.7289 0.701 0.674 0.7619 0.6943 0.8386 0.7646 0.8063 0.6718 0.7584 0.8144 0.7321 0.7831 0.7834 0.9016 0.8599
Nuclear Periphery 0.0168 0.0011 0.0019 0.0007 0.0007 0.0007 0.0071 0.001 0.0009 0.0054 0.0044 0.003 0.0013 0.0021 0.0027 0.0003 0.0002 0.0003
Nucleolus 0.0028 0.0013 0.002 0.0005 0.0009 0.0004 0.0009 0.0003 0.0006 0.0007 0.0004 0.0002 0.0011 0.001 0.0017 0.0002 0.0001 0.0002
Nucleus 0.0051 0.0051 0.0025 0.0034 0.001 0.0018 0.0319 0.0028 0.0083 0.0062 0.0069 0.0084 0.0019 0.0079 0.0032 0.0008 0.0003 0.0011
Peroxisomes 0.0151 0.0003 0.0029 0.0008 0.0034 0.0079 0.0118 0.0036 0.004 0.0009 0.0017 0.0105 0.0027 0.0037 0.0051 0.003 0.0017 0.0023
Punctate Nuclear 0.0187 0.0095 0.0532 0.1369 0.0017 0.0202 0.0333 0.0225 0.0509 0.0782 0.0635 0.0037 0.0122 0.046 0.0506 0.0788 0.0396 0.0124
Vacuole 0.0125 0.0012 0.0031 0.0002 0.0063 0.0006 0.0053 0.001 0.0008 0.0004 0.0034 0.0007 0.0012 0.0004 0.0017 0.0003 0.0001 0.0002
Vacuole Periphery 0.0036 0.0001 0.0006 0 0.002 0.0002 0.0015 0.0002 0.0001 0.0001 0.0009 0.0001 0.0004 0.0001 0.0002 0.0002 0 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 20.4064 8.9039 5.9625 11.3056 16.6936 17.2387 15.4803 12.1524 9.7086 19.4379
Translational Efficiency 0.9529 1.1771 0.8887 0.6523 0.713 1.023 0.5745 0.5697 0.7615 0.6835

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
153 1464 987 1143 1772 1552 150 2872 1925 3016 1137 4015

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 683.67 677.38 923.55 721.35 589.53 689.06 888.98 751.84 597.01 683.39 918.99 743.16
Standard Deviation 106.81 104.90 107.84 96.83 70.71 87.44 76.88 83.39 78.47 96.49 104.94 88.50
Intensity Change Log 2 — -0.013335 0.433890 0.077399 — 0.225064 0.592586 0.350860 — 0.101963 0.509546 0.210484

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000088 0.000434 0.000370 0.000131 0.000087 0.000207 0.000236 0.000081 0.000087 0.000317 0.000353 0.000095
Bud Neck 0.016622 0.042455 0.006019 0.005119 0.020860 0.040039 0.001200 0.012122 0.020523 0.041212 0.005383 0.010128
Bud Site 0.001968 0.015312 0.014093 0.009621 0.002943 0.014452 0.002115 0.014639 0.002865 0.014870 0.012513 0.013211
Cell Periphery 0.000184 0.000158 0.000148 0.000178 0.000125 0.000207 0.000267 0.000138 0.000130 0.000183 0.000164 0.000150
Cytoplasm 0.374599 0.385859 0.199775 0.448198 0.460681 0.398792 0.205336 0.466448 0.453839 0.392514 0.200509 0.461252
Cytoplasmic Foci 0.103467 0.286063 0.004677 0.030075 0.225222 0.211551 0.038586 0.011998 0.215545 0.247720 0.009151 0.017144
Eisosomes 0.000110 0.000209 0.000044 0.000047 0.000174 0.000167 0.000145 0.000022 0.000169 0.000187 0.000057 0.000029
Endoplasmic Reticulum 0.000927 0.000490 0.005072 0.000918 0.000581 0.000494 0.003739 0.000628 0.000609 0.000492 0.004896 0.000711
Endosome 0.008562 0.027406 0.001905 0.004342 0.010388 0.024389 0.004702 0.002364 0.010243 0.025853 0.002274 0.002927
Golgi 0.000134 0.005400 0.000066 0.001455 0.001839 0.004547 0.000094 0.000222 0.001704 0.004961 0.000070 0.000573
Lipid Particles 0.004663 0.010810 0.001317 0.001853 0.014130 0.011333 0.004688 0.000617 0.013378 0.011079 0.001761 0.000969
Mitochondria 0.000662 0.011995 0.000824 0.000930 0.005874 0.011514 0.000334 0.001439 0.005460 0.011748 0.000759 0.001294
Mitotic Spindle 0.003184 0.002462 0.004005 0.005126 0.001051 0.013416 0.005098 0.010221 0.001221 0.008098 0.004149 0.008770
None 0.005843 0.007226 0.004311 0.012129 0.005605 0.003049 0.002466 0.004629 0.005624 0.005077 0.004068 0.006764
Nuclear Periphery 0.000954 0.000404 0.002239 0.001329 0.000732 0.000509 0.001594 0.001234 0.000750 0.000458 0.002154 0.001261
Nuclear Periphery Foci 0.000610 0.000356 0.000893 0.000523 0.000351 0.000271 0.001400 0.000159 0.000372 0.000312 0.000960 0.000262
Nucleolus 0.003300 0.002765 0.000510 0.001218 0.001694 0.002130 0.000933 0.000879 0.001822 0.002438 0.000566 0.000975
Nucleus 0.364979 0.124048 0.700056 0.424812 0.200105 0.172689 0.626168 0.442005 0.213210 0.149078 0.690308 0.437110
Peroxisomes 0.002330 0.024893 0.000237 0.000398 0.006940 0.012357 0.000912 0.000561 0.006573 0.018442 0.000326 0.000514
Vacuole 0.106402 0.049374 0.053270 0.050139 0.039896 0.075774 0.099749 0.029049 0.045182 0.062959 0.059402 0.035053
Vacuole Periphery 0.000409 0.001880 0.000170 0.001460 0.000720 0.002113 0.000236 0.000546 0.000696 0.002000 0.000179 0.000806

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.43 -7.30 -0.31 4.41 7.58 -3.54 -5.03 -1.06 3.05 4.74 -6.33 -10.49 -1.71 5.63 9.72
Bud Neck -4.90 1.84 1.92 14.12 0.38 -7.10 13.29 4.95 11.08 -10.95 -9.49 10.07 6.52 16.71 -5.33
Bud Site -8.02 -3.59 -3.74 3.02 0.36 -6.88 0.13 -8.13 0.29 -7.01 -10.15 -3.22 -8.72 1.62 -1.96
Cell Periphery 0.73 1.15 0.70 -0.01 -0.93 -2.92 -7.02 -0.08 2.73 6.40 -3.36 -3.10 -0.53 2.81 2.23
Cytoplasm -1.39 7.51 -2.33 -2.20 -23.84 6.40 16.65 2.56 -4.43 -15.70 7.31 34.66 2.68 -5.55 -37.36
Cytoplasmic Foci -14.30 8.61 6.36 40.05 -13.02 2.03 28.66 41.75 36.49 4.11 -5.00 43.06 40.96 54.76 -9.14
Eisosomes -4.85 4.61 5.55 10.69 2.69 0.56 0.55 13.38 18.79 11.23 -1.32 8.67 13.28 19.13 12.54
Endoplasmic Reticulum 3.20 -11.07 0.83 -9.29 15.93 1.32 -7.58 -3.86 -5.85 7.23 2.72 -19.20 -4.72 -10.11 18.43
Endosome -8.16 3.68 2.52 13.19 -3.07 -7.90 5.44 10.18 13.77 4.42 -11.40 10.42 10.02 19.52 -0.26
Golgi -10.85 3.22 -1.78 6.02 -1.90 -5.00 10.15 9.30 8.46 -2.18 -8.35 10.29 5.76 11.72 -2.42
Lipid Particles -5.38 4.53 4.32 11.90 -0.49 2.08 7.97 12.78 11.84 8.83 2.12 11.56 12.76 17.16 7.94
Mitochondria -8.92 -1.30 -0.88 8.79 0.32 -4.20 8.09 6.48 8.66 -6.71 -5.90 7.43 6.69 12.18 -3.32
Mitotic Spindle 0.81 0.38 0.11 -2.02 -0.69 -5.37 -1.37 -6.66 1.24 -0.77 -5.00 -2.54 -6.54 -0.44 -3.03
None -1.13 1.13 -2.18 -1.13 -4.37 2.43 3.60 1.17 -2.21 -4.26 0.24 2.55 -0.50 -0.85 -4.95
Nuclear Periphery 4.43 -5.91 -0.93 -17.71 10.39 2.21 -7.83 -8.43 -18.98 3.02 3.60 -16.29 -8.89 -26.15 12.32
Nuclear Periphery Foci 1.88 -1.43 1.21 -2.28 5.90 1.25 -5.58 -0.74 -1.26 4.34 0.87 -8.39 -0.89 -1.43 5.63
Nucleolus -0.02 3.19 2.19 3.76 -2.92 -1.29 5.00 2.10 3.11 -2.72 -2.53 7.66 2.80 4.90 -5.39
Nucleus 9.20 -12.52 -2.08 -29.46 22.91 4.10 -16.46 -35.83 -37.98 5.51 11.08 -51.55 -34.87 -50.95 26.07
Peroxisomes -12.34 4.55 4.12 13.84 -2.69 -4.59 8.77 9.83 12.13 0.72 -10.10 10.66 10.19 17.90 -2.23
Vacuole 4.64 2.05 1.76 -8.43 -0.69 -10.29 -7.29 -1.47 8.73 7.05 -5.47 -10.18 -4.08 1.04 7.90
Vacuole Periphery -6.50 2.40 -1.71 1.58 -2.21 -7.26 7.42 3.00 8.47 -3.42 -8.69 9.71 0.27 7.04 -3.71
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Component of the mitotic spindle; binds to interpolar microtubules via its association with beta-tubulin (Tub2p); required for interpolar microtubules to provide an outward force on the spindle poles
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Stu1

Stu1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Stu1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available