Standard name
Human Ortholog
Description AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Cytoplasm 0.96 1.0 0.97 0.94 0.95 0.94 0.85 0.8 0.75 0.74 0.76 0.69 0.98 0.99 0.99 0.94 0.97 0.95 0.94 0.96 0.87 0.92 0.94 0.88
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.17 0.28 0.26 0.36 0.43 0.38 0.49 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 1 1 3 3 0 0 0 0 0 0 0 0 0 0 0 0 1 1
Bud 2 0 5 2 1 1 6 9 6 9 8 4 7 1 1 0 0 0 0 0 0 0 0 1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 5 3 4 4 4 10 7 7 8 14 3 5 15 10 19 7 2 5 0 0 0 0 0 0
Cytoplasm 268 267 259 174 307 293 283 411 246 313 136 107 594 713 743 246 117 99 265 255 249 434 482 410
Endoplasmic Reticulum 1 2 2 3 7 2 2 6 6 7 1 6 6 4 4 10 2 3 4 1 9 13 12 19
Endosome 1 0 0 0 0 0 0 2 1 1 0 0 1 0 0 2 1 1 1 0 0 1 2 2
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 0 0 0 1 4 2
Mitochondria 8 0 4 7 8 52 93 133 117 180 68 75 1 0 0 6 0 1 1 0 2 2 2 3
Nucleus 0 1 8 6 1 1 2 4 2 0 0 0 3 2 4 3 2 1 0 2 0 1 1 0
Nuclear Periphery 0 1 0 0 0 0 3 1 2 0 0 0 0 0 0 0 0 0 1 0 0 2 0 1
Nucleolus 2 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 2 1 0 1 5 1 1 8 2 4 4 1 6 3 2 10 1 2 2 2 19 11 5 14
Unique Cell Count 279 268 267 186 323 312 331 511 326 422 179 154 607 723 751 261 121 104 283 265 286 472 515 466
Labelled Cell Count 289 275 282 197 333 361 398 583 393 531 220 198 633 733 773 286 125 113 283 265 286 472 515 466


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.5 9.7 8.4 8.0 7.5 6.3 5.1 5.2 5.0 4.6 4.7 4.4 10.8 10.4 10.5 9.7 10.5 12.4 10.0 9.8 10.5
Std Deviation (1e-4) 1.5 2.0 1.6 1.4 1.4 1.4 1.3 1.2 1.2 1.0 1.0 1.4 2.1 2.1 2.0 2.1 2.1 2.8 1.8 1.7 1.7
Intensity Change (Log2) – – – -0.07 -0.15 -0.42 -0.72 -0.69 -0.74 -0.87 -0.85 -0.93 0.36 0.31 0.32 0.21 0.33 0.57 0.26 0.22 0.32

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 1.3 0 0 0.8 0 0 0 0.9 0 1.0 1.0 0 0
Cytoplasm -1.8 -1.2 -1.8 -4.8 -6.3 -7.3 -7.8 -6.8 -8.1 0.8 1.7 2.2 -1.5 -0.2 -0.9
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 2.4 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.8 6.2 8.8 8.5 10.3 0 0 0 0 0 0 0 0 0
Nucleus 0.1 0 0 0 0 0 0 0 0 0 0 0 -1.5 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 8.7395 11.0763 10.1812 9.1608 8.9698 9.7568 3.4761 6.0233 5.481 4.8794 4.2004 5.3093 5.7927 8.7389 7.7979 6.9608 7.6942 7.7508
Actin 0.0131 0.0022 0.0094 0.0011 0.0166 0.0045 0.0257 0.0005 0.0077 0.0559 0.0114 0.0074 0.0139 0.0003 0.0081 0.017 0.0011 0.0023
Bud 0.0007 0.0006 0.0006 0.0008 0.0023 0.0004 0.0009 0.0002 0.0049 0.0021 0.0007 0.0007 0.0003 0.0001 0.0006 0.0007 0.0003 0.0002
Bud Neck 0.0054 0.0003 0.0025 0.0078 0.0014 0.0012 0.006 0.0002 0.0005 0.0006 0.0006 0.0031 0.0011 0.0001 0.0006 0.0036 0.0276 0.0012
Bud Periphery 0.0009 0.0005 0.0011 0.0003 0.0029 0.0003 0.0009 0.0001 0.0014 0.0012 0.0006 0.0005 0.0002 0 0.0004 0.0008 0.0004 0.0003
Bud Site 0.0033 0.0036 0.0022 0.0081 0.0229 0.0002 0.0044 0.0011 0.0144 0.0022 0.0012 0.0003 0.0029 0.0013 0.0133 0.0074 0.0003 0.0003
Cell Periphery 0.0008 0.0006 0.001 0.0003 0.0004 0.0003 0.0003 0.0003 0.0005 0.0003 0.0001 0.0001 0.0003 0.0005 0.0005 0.0007 0.0003 0.0003
Cytoplasm 0.7455 0.9725 0.8783 0.9033 0.7483 0.9435 0.6687 0.9424 0.8626 0.8028 0.7677 0.893 0.819 0.9846 0.9219 0.8233 0.9043 0.9633
Cytoplasmic Foci 0.0313 0.0031 0.0166 0.0198 0.0142 0.0063 0.0575 0.0064 0.0277 0.0171 0.0535 0.0165 0.042 0.0039 0.0128 0.0269 0.0073 0.005
Eisosomes 0.0009 0.0001 0.0001 0 0.0002 0 0.0003 0.0002 0.0001 0.0004 0.0001 0 0.0001 0 0 0.0015 0 0
Endoplasmic Reticulum 0.0576 0.0034 0.0095 0.0059 0.0035 0.0156 0.0165 0.0038 0.0062 0.0021 0.0044 0.0142 0.013 0.0022 0.0065 0.0026 0.0019 0.0119
Endosome 0.0331 0.0029 0.0239 0.0211 0.1006 0.0088 0.0675 0.0043 0.0258 0.0395 0.0293 0.0314 0.0317 0.0017 0.013 0.0281 0.0106 0.0068
Golgi 0.01 0.0006 0.0098 0.0023 0.017 0.0032 0.0306 0.0005 0.0081 0.0137 0.0288 0.0176 0.0129 0.0003 0.0043 0.0125 0.0077 0.0018
Lipid Particles 0.0048 0.0001 0.0045 0.0024 0.0037 0.0033 0.0305 0.0001 0.0077 0.0108 0.0245 0.0012 0.0168 0.0001 0.001 0.0076 0.0147 0.0001
Mitochondria 0.0263 0.0004 0.0055 0.001 0.0237 0.0048 0.0122 0.0001 0.0087 0.0365 0.0513 0.0072 0.0045 0 0.002 0.0289 0.0144 0.0036
None 0.0172 0.0041 0.0098 0.0018 0.0009 0.0022 0.0254 0.0368 0.0113 0.0014 0.0045 0.0023 0.0173 0.0029 0.008 0.0033 0.0022 0.0008
Nuclear Periphery 0.0079 0.0005 0.0062 0.0013 0.0039 0.0007 0.0025 0.0003 0.0017 0.0014 0.0006 0.0009 0.0019 0.0003 0.0007 0.0007 0.0004 0.0004
Nucleolus 0.0011 0 0.0006 0.0009 0.0005 0 0.0009 0.0001 0.0003 0.0002 0.0001 0 0.0004 0 0.0002 0.0007 0.0001 0
Nucleus 0.0215 0.001 0.0042 0.0022 0.0017 0.0009 0.002 0.0004 0.0011 0.0008 0.0006 0.0005 0.0011 0.0004 0.0008 0.0012 0.0006 0.0005
Peroxisomes 0.004 0 0.0021 0.0023 0.003 0.001 0.0311 0 0.0057 0.0011 0.017 0.0008 0.0104 0 0.0012 0.025 0.0023 0.0001
Punctate Nuclear 0.0035 0.0001 0.0013 0.001 0.0006 0.0001 0.0072 0.0001 0.0008 0.0002 0.0007 0.0003 0.0057 0.0001 0.0003 0.0004 0.0001 0
Vacuole 0.0094 0.0027 0.0092 0.0145 0.023 0.002 0.0072 0.0021 0.0024 0.0072 0.0016 0.0014 0.0039 0.0009 0.0033 0.006 0.0027 0.0008
Vacuole Periphery 0.0017 0.0004 0.0015 0.0017 0.0087 0.0006 0.002 0.0001 0.0006 0.0027 0.0007 0.0006 0.0006 0.0001 0.0003 0.0011 0.0007 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 26.9208 16.2521 14.8428 15.9251 18.132 18.1702 23.8587 22.3949 17.8133 22.1193
Translational Efficiency 0.62 1.1401 0.7011 0.5861 0.8857 0.8895 0.7528 0.6441 0.5704 0.7594

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1444 1260 1214 1277 1409 1089 492 2219 2853 2349 1706 3496

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 907.84 1032.29 1349.44 1109.85 956.66 1125.03 1173.48 1078.45 931.95 1075.28 1298.69 1089.92
Standard Deviation 112.82 216.10 186.76 162.32 170.19 163.76 147.50 152.39 146.09 199.05 193.52 156.82
Intensity Change Log 2 — 0.185338 0.571851 0.289855 — 0.233885 0.294715 0.172881 — 0.210451 0.436306 0.231022

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000158 0.000273 0.000273 0.001594 0.000256 0.000202 0.000108 0.000159 0.000206 0.000240 0.000225 0.000683
Bud Neck 0.002642 0.000851 0.000817 0.002075 0.001144 0.000788 0.002346 0.003200 0.001902 0.000822 0.001258 0.002789
Bud Site 0.012347 0.021015 0.006495 0.033903 0.018686 0.018034 0.006815 0.015645 0.015478 0.019633 0.006588 0.022314
Cell Periphery 0.000249 0.000124 0.000145 0.000126 0.000209 0.000090 0.000201 0.000044 0.000229 0.000108 0.000161 0.000074
Cytoplasm 0.678506 0.831496 0.813317 0.720311 0.746537 0.810108 0.502376 0.683349 0.712105 0.821580 0.723643 0.696850
Cytoplasmic Foci 0.200304 0.079201 0.030552 0.061462 0.143836 0.111805 0.085665 0.029272 0.172416 0.094316 0.046446 0.041030
Eisosomes 0.000058 0.000007 0.000004 0.000012 0.000017 0.000007 0.000173 0.000014 0.000038 0.000007 0.000052 0.000013
Endoplasmic Reticulum 0.004735 0.001987 0.001505 0.000295 0.003212 0.000829 0.001149 0.000300 0.003983 0.001450 0.001402 0.000298
Endosome 0.013638 0.007928 0.004243 0.007561 0.013121 0.007185 0.010306 0.004869 0.013383 0.007583 0.005992 0.005852
Golgi 0.007213 0.005489 0.001799 0.005017 0.007612 0.010260 0.000240 0.001266 0.007410 0.007701 0.001349 0.002636
Lipid Particles 0.002597 0.000845 0.001523 0.000935 0.001432 0.000486 0.001626 0.000629 0.002021 0.000678 0.001553 0.000741
Mitochondria 0.000628 0.000374 0.000469 0.001065 0.001210 0.001145 0.000033 0.000422 0.000916 0.000731 0.000343 0.000656
Mitotic Spindle 0.001805 0.000612 0.001426 0.036890 0.003385 0.003865 0.000269 0.016784 0.002585 0.002120 0.001093 0.024128
None 0.001820 0.002375 0.001279 0.000492 0.000925 0.000502 0.000382 0.001247 0.001378 0.001507 0.001020 0.000971
Nuclear Periphery 0.000067 0.000072 0.000112 0.000145 0.000043 0.000010 0.000208 0.000141 0.000055 0.000043 0.000140 0.000142
Nuclear Periphery Foci 0.001651 0.000872 0.002964 0.001756 0.001028 0.000163 0.002998 0.000847 0.001343 0.000543 0.002974 0.001179
Nucleolus 0.000227 0.000558 0.000100 0.000235 0.000277 0.000065 0.000221 0.000278 0.000252 0.000329 0.000135 0.000262
Nucleus 0.009240 0.006923 0.014883 0.010143 0.007545 0.002584 0.066498 0.023811 0.008403 0.004911 0.029768 0.018819
Peroxisomes 0.000863 0.000833 0.000148 0.002374 0.000614 0.000802 0.000439 0.000953 0.000740 0.000819 0.000232 0.001472
Vacuole 0.057828 0.034102 0.116652 0.111020 0.044182 0.025938 0.317497 0.215101 0.051089 0.030317 0.174574 0.177083
Vacuole Periphery 0.003424 0.004064 0.001294 0.002590 0.004728 0.005133 0.000450 0.001668 0.004068 0.004560 0.001051 0.002005

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.56 -2.69 -2.33 -1.96 -1.86 0.95 3.67 3.32 1.62 -0.10 -0.96 -1.05 -1.70 -1.39 -1.30
Bud Neck 9.42 8.87 3.44 -7.51 -6.75 3.90 -4.54 -5.99 -7.40 -1.29 10.07 4.62 -2.53 -9.27 -5.87
Bud Site -5.50 5.84 -4.87 -0.67 -7.65 0.32 7.42 5.05 3.96 -2.52 -3.30 9.74 0.28 3.21 -7.63
Cell Periphery 8.06 5.88 10.27 3.43 5.18 4.38 1.24 6.75 7.16 5.92 7.78 4.26 11.76 9.23 10.43
Cytoplasm -17.79 -13.33 2.45 17.64 13.96 -6.85 17.11 10.16 17.04 -11.05 -17.23 -0.85 8.57 25.16 7.24
Cytoplasmic Foci 21.61 35.60 30.28 7.17 -6.83 5.11 10.48 26.56 18.19 13.40 18.53 35.25 41.45 19.66 5.52
Eisosomes 15.25 16.50 13.57 -5.00 -9.96 3.61 -3.49 2.22 -2.31 3.68 14.00 -0.42 11.65 -4.26 3.08
Endoplasmic Reticulum 2.49 3.41 4.97 2.74 3.51 3.06 2.91 4.03 2.88 3.92 3.69 4.19 6.41 3.47 4.36
Endosome 5.41 12.52 10.43 3.44 -0.42 4.88 3.28 9.62 5.17 9.19 7.17 11.45 14.85 6.34 4.73
Golgi 3.22 13.64 5.92 3.56 -0.80 -2.25 18.16 15.86 8.48 -2.65 -0.52 19.29 15.76 9.97 0.05
Lipid Particles 7.20 3.68 6.70 -1.30 3.83 7.64 0.02 6.43 -0.84 5.29 9.65 2.64 9.51 -0.57 7.19
Mitochondria 1.06 0.45 0.28 -0.87 -0.29 0.07 1.70 1.36 1.54 -5.07 0.41 1.32 1.49 1.27 -0.19
Mitotic Spindle 1.34 0.31 -7.02 -7.61 -7.33 -0.26 2.33 -4.23 -3.91 -7.39 0.45 1.77 -8.24 -8.79 -10.05
None -0.72 1.07 3.29 2.47 1.06 2.09 2.86 -0.39 -2.85 -3.70 -0.30 1.09 2.14 1.58 0.15
Nuclear Periphery -0.12 -2.76 -7.52 -4.36 -5.68 5.15 -7.61 -12.80 -16.85 -0.79 0.59 -6.83 -13.53 -8.60 -6.16
Nuclear Periphery Foci 1.21 -2.36 -0.09 -4.58 5.20 5.34 -6.03 1.55 -2.95 6.99 2.38 -4.81 0.85 -3.68 9.03
Nucleolus -1.04 2.43 0.30 1.11 -2.16 1.94 0.73 0.21 -8.36 -1.97 -0.42 2.03 0.23 0.53 -4.56
Nucleus 2.60 -7.23 -10.31 -10.36 -2.59 5.27 -7.94 -14.03 -24.74 4.78 5.30 -9.72 -17.88 -23.38 1.73
Peroxisomes -0.15 6.28 -1.31 -1.15 -3.27 -2.12 3.00 0.11 1.07 -0.82 -0.95 8.02 -0.72 -0.11 -3.56
Vacuole 7.13 -8.70 -21.48 -24.95 -9.63 6.66 -23.24 -35.84 -40.19 5.79 9.52 -19.76 -41.19 -46.46 -7.56
Vacuole Periphery -1.02 5.48 4.29 4.77 -0.17 -0.38 6.72 5.57 4.59 -2.03 -0.80 8.04 7.23 6.70 -0.23
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-4

Ypk3

Ypk3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ypk3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available