Standard name
Description Component of the histone deacetylase Rpd3L complex; possibly involved in cell fusion and invasive growth; relocalizes to the cytosol in response to hypoxia

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0.05 0 0.05 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.06 0.06 0.05 0 0 0 0 0 0 0.11 0.17 0.16 0.15 0.09 0.14 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.07 0.15 0 0.07 0.07 0.15 0.25 0.17 0.18 0.26 0.26 0.31 0 0 0 0.06 0.07 0 0 0 0 0 0 0
Nucleus 0.88 0.9 0.88 0.83 0.81 0.74 0.69 0.63 0.67 0.63 0.58 0.56 0.87 0.81 0.78 0.72 0.8 0.76 0.8 0.83 0.74 0.81 0.78 0.67
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.35 0.18 0.18 0.17 0.19 0.32 0.33 0.46 0.4 0.46 0.52 0.46 0.08 0.06 0.06 0 0 0 0.14 0.12 0.16 0.09 0.12 0.17
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.06 0.08 0 0 0 0 0 0.07
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0
Bud 0 3 0 1 1 0 5 4 4 4 4 2 0 1 0 0 2 0 2 4 2 1 4 3
Bud Neck 0 0 0 0 1 0 1 0 7 2 4 3 0 0 0 0 2 0 1 1 1 0 0 1
Bud Site 1 1 0 2 1 9 13 14 30 26 29 21 0 1 1 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 1 0 0 0 0 0 0 0 0
Cytoplasm 4 4 11 15 13 21 21 22 15 15 11 16 47 110 94 42 27 42 0 0 0 6 4 4
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 8 9 6 0 0 1 0 0 0
Endosome 0 0 3 0 2 0 0 0 0 0 0 0 1 1 5 8 5 9 4 2 10 2 8 14
Golgi 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 2 5 1 0 6 2 3 2
Mitochondria 30 71 15 16 17 66 133 105 104 169 154 201 1 1 0 17 19 8 1 2 2 2 2 8
Nucleus 395 436 387 195 184 334 371 378 382 415 346 358 386 533 459 197 234 228 368 405 356 365 427 433
Nuclear Periphery 1 0 2 1 1 4 4 4 1 11 4 6 3 1 5 1 1 1 0 0 1 0 0 1
Nucleolus 157 86 81 40 44 143 178 274 229 302 311 297 34 37 38 9 6 8 65 56 75 42 64 110
Peroxisomes 1 1 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 1 0 0 0
SpindlePole 1 3 4 1 0 1 0 2 2 5 3 0 6 13 11 7 4 6 1 1 2 6 7 14
Vac/Vac Membrane 1 6 3 1 6 7 7 3 4 7 5 4 0 6 6 16 18 24 10 12 9 19 23 48
Unique Cell Count 448 486 441 236 227 452 540 600 570 662 593 639 446 660 588 273 291 301 460 491 479 452 551 648
Labelled Cell Count 591 611 507 273 270 585 733 806 778 957 871 908 479 705 621 306 329 337 460 491 479 452 551 648


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.4 6.3 7.1 6.4 6.5 5.9 5.7 5.7 5.7 5.5 5.3 4.8 8.3 8.1 7.6 6.9 6.9 7.2 8.4 8.3 9.0
Std Deviation (1e-4) 1.1 1.5 1.8 2.1 2.2 2.0 2.0 2.1 1.9 1.9 2.2 1.9 2.0 1.9 1.9 1.6 1.7 2.0 1.8 1.7 1.7
Intensity Change (Log2) -0.14 -0.11 -0.27 -0.3 -0.31 -0.31 -0.37 -0.42 -0.55 0.23 0.19 0.1 -0.03 -0.03 0.03 0.25 0.23 0.35


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 3.3 3.2 4.9 4.2 4.7 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 2.5 2.1 1.7 1.2 1.1 0.1 -0.2 -0.7 0 4.8 7.4 7.1 6.4 4.0 6.0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 2.0 2.3 5.8 9.2 7.0 7.3 9.7 9.7 0 -3.6 -4.4 -4.5 1.8 2.0 -0.6
Nucleus -1.8 -2.3 -5.3 -7.1 -8.9 -7.7 -9.2 -10.3 -11.1 -0.5 -3.1 -4.0 -5.2 -2.7 -4.3
Nuclear Periphery 0 0 0 0 0 0 1.8 0 0 0 0 0 0 0 0
Nucleolus -0.5 0.3 4.6 5.2 9.2 7.5 9.3 11.2 0 -4.8 -6.7 -5.9 -5.9 -6.7 -6.5
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 1.4 1.3 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 4.2 4.4 5.2


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rxt2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available