Standard name
Human Ortholog
Description Regulator of filamentous growth; interacts with FLO11 promoter and regulates FLO11 expression; binds to transcription factors Flo8p and Mss11p; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YDL233W is not an essential gene
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.14 0.17 0.28 0.21 0.33 0.29 0.27 0.32 0.28 0.33 0.28 0.3 0.22 0.36 0.46 0.2 0.18 0.17 0.07 0.18 0.19 0.21 0.25 0.22
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0.09 0.05 0 0 0 0 0 0
Endosome 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.06 0.09 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.36 0.45 0.52 0.64 0.52 0.7 0.73 0.71 0.73 0.74 0.75 0.81 0.06 0.06 0.05 0.1 0 0.07 0 0 0 0 0 0
Nucleus 0.45 0.3 0.37 0.41 0.22 0.23 0.16 0.2 0.25 0.24 0.19 0.14 0.4 0.23 0.15 0.42 0.49 0.48 0.55 0.46 0.39 0.47 0.34 0.18
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.15
Vac/Vac Membrane 0.24 0.37 0.13 0.06 0.14 0.08 0.06 0 0.06 0 0 0.05 0.42 0.46 0.46 0.27 0.27 0.31 0.28 0.24 0.3 0.21 0.21 0.24
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2
Bud 2 0 0 0 1 5 3 7 0 2 5 1 0 0 1 2 0 0 6 2 2 3 9 23
Bud Neck 0 0 0 0 0 0 0 2 1 0 1 0 0 0 0 0 0 0 2 0 0 0 3 10
Bud Site 2 0 0 1 1 1 0 6 7 6 2 2 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0
Cytoplasm 46 18 28 29 61 83 97 172 74 89 66 81 72 126 188 33 12 18 31 21 22 40 89 89
Endoplasmic Reticulum 0 1 0 0 0 3 0 0 1 0 0 1 0 0 1 17 6 5 0 0 0 0 2 4
Endosome 23 0 0 1 4 0 0 1 0 1 0 0 9 7 7 13 4 10 5 3 0 3 9 14
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2 3
Mitochondria 120 47 52 89 98 202 261 380 194 199 175 218 18 21 20 16 3 8 7 1 5 2 11 14
Nucleus 148 32 37 57 41 65 59 107 67 64 45 39 128 81 61 69 33 52 262 55 46 89 124 75
Nuclear Periphery 0 1 0 1 0 1 1 2 1 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0
Nucleolus 6 1 0 0 1 0 0 0 0 2 0 0 0 1 1 6 0 2 0 0 0 1 1 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
SpindlePole 0 0 0 0 0 1 1 5 0 0 0 1 0 0 0 6 2 2 11 3 2 6 24 60
Vac/Vac Membrane 81 39 13 9 26 23 21 24 16 9 8 14 134 163 187 45 18 33 133 29 35 40 75 98
Unique Cell Count 331 105 100 139 187 288 359 536 266 269 232 269 322 354 408 166 67 108 473 122 120 192 362 413
Labelled Cell Count 428 139 130 187 233 384 443 706 361 373 302 357 361 400 467 207 78 131 473 122 120 192 362 413


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.0 3.9 3.6 3.4 3.7 3.1 2.8 3.1 3.1 2.7 2.9 2.7 4.9 4.6 4.7 5.0 6.0 7.1 4.7 4.5 5.3
Std Deviation (1e-4) 0.6 0.6 0.9 0.7 1.1 1.0 0.9 1.2 1.3 1.2 1.2 1.0 0.9 1.0 1.5 1.3 1.3 1.8 1.1 1.1 1.8
Intensity Change (Log2) – – – -0.06 0.03 -0.21 -0.37 -0.19 -0.22 -0.38 -0.29 -0.4 0.44 0.35 0.39 0.49 0.74 0.99 0.4 0.32 0.56

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 2.7 2.3 3.0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.5894 2.1662 1.7678 1.696 1.5386 2.0063 -0.8928 0.3564 -0.0287 0.141 -0.4983 0.1096 1.673 1.8244 1.7528 1.7194 1.4095 1.7932
Actin 0.0002 0.0006 0.0003 0.0002 0.0002 0.0003 0.0003 0.0001 0.0011 0.0001 0.0002 0.0002 0.0401 0.0004 0.0012 0.0007 0.0036 0.0042
Bud 0.0001 0.0001 0.0014 0.0001 0.0008 0.0019 0.0001 0 0.0001 0 0 0 0.0007 0.0001 0.0001 0.0002 0.0001 0.0003
Bud Neck 0.0006 0.0003 0.0005 0.001 0.0006 0.0021 0.0003 0.0002 0.0003 0.0003 0.0002 0.002 0.0081 0.0004 0.0004 0.0008 0.0005 0.0048
Bud Periphery 0 0.0001 0.0002 0 0.0004 0.0007 0.0003 0 0.0002 0 0 0 0.0007 0.0001 0.0001 0.0001 0.0001 0.0003
Bud Site 0.0002 0.0006 0.0028 0.0003 0.0003 0.0002 0.0004 0.0004 0.0007 0.0001 0 0.0001 0.0074 0.0009 0.0005 0.0003 0.0003 0.0004
Cell Periphery 0.0001 0 0.0002 0 0.0001 0 0.0006 0 0.0001 0 0 0 0.0003 0.0001 0 0 0 0.0001
Cytoplasm 0.0883 0.1016 0.0941 0.0203 0.0767 0.066 0.1277 0.1565 0.1282 0.2499 0.1244 0.0732 0.066 0.1039 0.0912 0.1511 0.0597 0.0543
Cytoplasmic Foci 0.0107 0.0068 0.0022 0.0011 0.01 0.0047 0.0018 0.0012 0.0058 0.0052 0.0008 0.0021 0.0147 0.0021 0.0033 0.0015 0.0044 0.0083
Eisosomes 0.0001 0 0 0 0.0002 0 0.0004 0 0.0001 0 0 0 0.0005 0 0 0 0.0001 0
Endoplasmic Reticulum 0.0041 0.0017 0.0023 0.0004 0.0027 0.0014 0.0053 0.0035 0.0037 0.0069 0.0012 0.0013 0.0023 0.0073 0.0018 0.0037 0.0062 0.0018
Endosome 0.0065 0.0027 0.002 0.0004 0.0018 0.0032 0.0086 0.0011 0.0094 0.007 0.0007 0.0118 0.0039 0.0051 0.0017 0.0021 0.0268 0.004
Golgi 0.0001 0.0035 0.0001 0.0001 0 0.0013 0.0011 0 0.0032 0.0001 0 0.0155 0.0026 0.0001 0.0001 0.0001 0.0091 0.0011
Lipid Particles 0.0004 0.0001 0.0003 0.0001 0.0006 0.0008 0.0205 0.0001 0.0077 0.0003 0 0.0002 0.0041 0.0004 0.0002 0.0001 0.0142 0.0033
Mitochondria 0.0003 0.0004 0.001 0.0002 0.0402 0.0009 0.0625 0.0002 0.0157 0.0005 0.0006 0.0005 0.0078 0.0005 0.0005 0.0009 0.002 0.0007
None 0.0657 0.0057 0.0715 0.0562 0.086 0.0436 0.2332 0.3062 0.1763 0.3075 0.2786 0.1341 0.117 0.0946 0.1629 0.1168 0.1079 0.0588
Nuclear Periphery 0.0143 0.0156 0.0165 0.005 0.0095 0.0098 0.0141 0.011 0.0128 0.0174 0.0081 0.0082 0.0102 0.0155 0.0105 0.0203 0.0187 0.0081
Nucleolus 0.0028 0.0027 0.0036 0.0043 0.0082 0.0049 0.0026 0.0019 0.0024 0.0013 0.0009 0.0037 0.0046 0.0029 0.0028 0.002 0.0021 0.0055
Nucleus 0.7775 0.8439 0.7649 0.8083 0.7508 0.8237 0.4968 0.5114 0.6122 0.392 0.5803 0.7346 0.687 0.7498 0.7039 0.6769 0.7184 0.8045
Peroxisomes 0.0001 0.0006 0.0001 0 0.0021 0.0008 0.0005 0 0.0014 0.0001 0 0 0.0031 0.0001 0.0002 0.0002 0.0116 0.0034
Punctate Nuclear 0.0235 0.0113 0.034 0.1017 0.0069 0.0328 0.0091 0.0049 0.0166 0.0074 0.0033 0.0116 0.017 0.0071 0.0177 0.0213 0.0099 0.0349
Vacuole 0.004 0.0013 0.0018 0.0002 0.0013 0.0007 0.0097 0.001 0.0018 0.0031 0.0005 0.0006 0.0014 0.0082 0.0007 0.0006 0.0033 0.0009
Vacuole Periphery 0.0004 0.0002 0.0003 0.0001 0.0004 0.0002 0.0042 0.0001 0.0004 0.0005 0.0002 0.0002 0.0004 0.0005 0.0002 0.0003 0.0011 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 7.2118 5.7306 5.3154 10.9786 5.1947 12.013 9.7777 8.0658 12.3757 11.8859
Translational Efficiency 1.4224 1.6627 2.0379 0.8592 1.899 0.9823 1.2095 1.3335 0.995 0.9989

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
984 872 2385 1257 1558 927 2012 617 2542 1799 4397 1874

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 609.51 663.76 855.47 947.18 690.84 734.99 849.88 988.16 659.36 700.46 852.91 960.67
Standard Deviation 71.59 128.17 103.24 139.98 91.37 91.26 99.58 144.42 93.11 116.28 101.62 142.76
Intensity Change Log 2 — 0.123012 0.489067 0.635989 — 0.089373 0.298908 0.516393 — 0.105238 0.391168 0.573687

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000047 0.000318 0.000203 0.001145 0.000032 0.000353 0.000196 0.005621 0.000038 0.000336 0.000200 0.002619
Bud Neck 0.001259 0.009965 0.009641 0.027144 0.000651 0.010131 0.006689 0.022401 0.000886 0.010051 0.008291 0.025583
Bud Site 0.000623 0.003693 0.002773 0.013574 0.000233 0.004248 0.001719 0.046647 0.000384 0.003979 0.002291 0.024463
Cell Periphery 0.000111 0.000204 0.000081 0.000173 0.000115 0.000132 0.000151 0.001180 0.000113 0.000167 0.000113 0.000504
Cytoplasm 0.230022 0.215096 0.032094 0.035799 0.290777 0.139148 0.064513 0.042737 0.267259 0.175961 0.046929 0.038084
Cytoplasmic Foci 0.027118 0.047269 0.000196 0.006702 0.023090 0.044655 0.001944 0.004839 0.024649 0.045922 0.000996 0.006088
Eisosomes 0.000029 0.000062 0.000012 0.000034 0.000031 0.000058 0.000022 0.000064 0.000030 0.000060 0.000017 0.000044
Endoplasmic Reticulum 0.000351 0.002972 0.004208 0.008515 0.000664 0.002201 0.003322 0.007112 0.000543 0.002574 0.003802 0.008053
Endosome 0.000665 0.006454 0.000338 0.006774 0.000650 0.003755 0.001135 0.009381 0.000656 0.005063 0.000703 0.007633
Golgi 0.000281 0.001882 0.000026 0.003746 0.000077 0.001273 0.000135 0.003706 0.000156 0.001568 0.000076 0.003733
Lipid Particles 0.001596 0.005198 0.000152 0.000588 0.001679 0.005402 0.000435 0.000674 0.001647 0.005303 0.000281 0.000616
Mitochondria 0.000457 0.004098 0.000896 0.010946 0.000339 0.007816 0.001241 0.014423 0.000385 0.006014 0.001054 0.012091
Mitotic Spindle 0.000486 0.005182 0.002041 0.099973 0.000019 0.004933 0.008008 0.055944 0.000200 0.005054 0.004771 0.085477
None 0.021937 0.037722 0.002787 0.008887 0.011100 0.006995 0.006295 0.009933 0.015295 0.021889 0.004392 0.009232
Nuclear Periphery 0.000477 0.001154 0.001523 0.003825 0.000534 0.001423 0.001353 0.002390 0.000512 0.001293 0.001445 0.003352
Nuclear Periphery Foci 0.000151 0.001156 0.000150 0.004015 0.000247 0.000466 0.000218 0.002050 0.000210 0.000801 0.000181 0.003368
Nucleolus 0.002126 0.008505 0.000647 0.010509 0.001144 0.005806 0.001081 0.006454 0.001524 0.007114 0.000846 0.009174
Nucleus 0.708445 0.621472 0.937628 0.725907 0.664164 0.736709 0.894698 0.737309 0.681305 0.680852 0.917984 0.729661
Peroxisomes 0.001083 0.006043 0.000054 0.001555 0.000312 0.008913 0.000142 0.004549 0.000611 0.007522 0.000094 0.002541
Vacuole 0.002633 0.020119 0.004472 0.023934 0.004039 0.014127 0.006218 0.017881 0.003495 0.017031 0.005271 0.021941
Vacuole Periphery 0.000102 0.001437 0.000079 0.006254 0.000101 0.001458 0.000484 0.004706 0.000102 0.001448 0.000264 0.005744

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.78 -7.82 -23.84 -18.49 -20.57 -4.28 -16.82 -6.52 -5.90 -6.06 -6.96 -15.92 -11.90 -10.12 -10.61
Bud Neck -6.45 -10.01 -19.96 -14.57 -15.35 -7.27 -11.60 -16.11 -11.53 -12.06 -9.80 -15.32 -25.37 -18.52 -19.37
Bud Site -5.63 -4.08 -13.85 -10.79 -11.30 -5.12 -7.94 -10.31 -9.40 -9.88 -7.57 -7.01 -15.53 -13.21 -14.12
Cell Periphery -5.18 3.35 -7.47 0.84 -11.48 -1.35 -1.46 -8.47 -8.15 -8.20 -4.85 1.33 -9.85 -7.45 -10.11
Cytoplasm 1.65 24.69 25.22 22.72 2.57 16.77 33.49 37.37 16.19 7.40 12.88 42.73 45.73 27.74 7.84
Cytoplasmic Foci -5.40 11.99 10.15 12.74 -3.87 -6.41 14.53 9.20 11.51 -3.56 -8.56 19.00 14.72 17.46 -4.95
Eisosomes -8.49 6.68 -11.05 1.25 -19.60 -5.49 1.18 -9.93 -3.61 -12.03 -9.11 4.49 -13.45 -1.37 -21.27
Endoplasmic Reticulum -8.67 -14.43 -23.08 -12.63 -8.58 -7.75 -18.57 -16.95 -12.04 -7.98 -11.38 -21.14 -28.09 -17.90 -11.90
Endosome -6.78 1.71 -5.64 3.46 -6.49 -5.15 -1.55 -3.50 -0.32 -3.05 -8.53 -0.35 -6.48 2.32 -6.24
Golgi -3.13 1.17 -3.48 0.83 -5.18 -2.98 -1.06 -4.54 -1.00 -4.41 -4.44 0.97 -6.03 0.01 -6.72
Lipid Particles -6.98 5.32 2.90 9.69 -11.24 -4.90 8.75 3.81 5.75 -5.75 -7.91 10.16 5.46 9.85 -11.00
Mitochondria -5.92 -6.23 -4.85 -0.83 -4.18 -5.88 -5.04 -5.55 -0.14 -4.67 -7.82 -7.75 -7.23 -0.03 -6.04
Mitotic Spindle -2.58 -3.32 -18.18 -17.05 -17.73 -3.83 -5.54 -11.54 -10.86 -10.39 -4.42 -6.64 -21.53 -20.31 -20.34
None -3.04 8.31 5.45 6.66 -10.32 3.23 4.72 2.35 -0.79 -2.41 -2.55 9.96 5.55 6.04 -8.23
Nuclear Periphery -7.72 -16.63 -15.40 -12.19 -9.31 -7.31 -14.83 -7.46 -4.42 -3.25 -10.33 -22.54 -16.91 -12.14 -9.56
Nuclear Periphery Foci -6.19 -1.56 -8.03 -7.09 -7.46 -3.46 -2.24 -5.55 -5.41 -5.43 -6.99 -2.07 -9.72 -9.06 -9.28
Nucleolus -6.40 2.63 -15.24 -12.63 -15.62 -5.13 -3.47 -9.93 -8.48 -9.54 -8.37 -0.96 -18.33 -15.46 -18.21
Nucleus 6.32 -22.86 5.75 -0.79 28.50 -5.31 -27.70 2.33 5.78 17.29 0.80 -37.58 5.32 4.13 32.54
Peroxisomes -4.42 1.39 -0.48 4.91 -7.79 -6.13 3.27 -3.12 3.94 -3.35 -7.79 1.79 -3.15 6.49 -6.27
Vacuole -9.59 -6.26 -10.06 -0.61 -7.40 -7.96 -7.23 -8.38 -3.43 -6.07 -12.32 -9.03 -12.74 -2.77 -9.35
Vacuole Periphery -5.15 0.85 -3.40 -0.17 -3.44 -2.67 -1.66 -2.27 -0.42 -1.87 -4.64 -1.53 -4.05 -0.37 -3.66
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Regulator of filamentous growth; interacts with FLO11 promoter and regulates FLO11 expression; binds to transcription factors Flo8p and Mss11p; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YDL233W is not an essential gene
Localization
Cell Percentages nucleus (36%), cytoplasm (11%), mixed (51%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Mfg1

Mfg1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mfg1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
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