Standard name
Human Ortholog
Description Protein involved in assembly of the RNA polymerase III (Pol III) complex; high copy suppressor of Pol III assembly mutation and psk1 psk2 mutations that confer temperature-sensitivity for galactose utilization; physically interacts with Pol III; proposed to bind single-stranded nucleic acids via its R3H domain
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0 0 0 0 0 0
Cytoplasm 0.95 0.98 0.97 0.96 0.96 0.84 0.75 0.71 0.6 0.53 0.51 0.51 0.99 0.98 0.98 0.91 0.91 0.89 0.91 0.91 0.88 0.91 0.84 0.58
Endoplasmic Reticulum 0 0 0 0 0 0 0.06 0.05 0 0.06 0 0 0 0 0 0 0.05 0 0 0 0.05 0.05 0.06 0.13
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.28 0.27 0.34 0.47 0.56 0.59 0.65 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 2 0 0 1 1 1 0 0 2 1 2 4 0 1 1 1 4 2 1 0 0 0 2 9
Bud 2 1 3 2 2 2 4 8 7 3 7 7 6 5 5 0 0 0 2 0 0 0 1 7
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 2
Bud Site 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 2 0 5 6 8 12 4 10 10 7 10 5 12 15 16 11 9 0 0 0 0 0 0
Cytoplasm 488 145 116 217 279 242 281 284 189 167 170 202 447 711 844 388 238 101 469 144 107 250 392 334
Endoplasmic Reticulum 0 1 2 4 3 11 22 19 13 20 9 15 3 6 5 14 13 4 19 2 5 12 30 72
Endosome 10 0 0 1 1 0 5 3 5 0 0 0 0 4 6 18 5 2 3 0 1 0 10 52
Golgi 0 0 1 0 0 1 0 0 0 0 1 0 1 2 0 3 0 1 0 0 0 1 8 22
Mitochondria 14 1 2 8 12 82 99 135 149 176 199 258 0 1 1 15 10 4 2 1 2 1 4 19
Nucleus 2 2 0 1 0 0 1 0 2 0 4 2 0 1 1 0 0 1 1 1 0 0 0 1
Nuclear Periphery 0 0 0 0 0 1 1 0 2 3 1 2 0 0 0 0 0 0 1 0 0 0 1 2
Nucleolus 1 0 0 0 0 0 0 0 1 0 0 0 1 0 2 1 2 2 0 0 0 0 0 1
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 2 1 0 0 0 3 16
Vac/Vac Membrane 15 0 0 4 4 5 8 10 6 10 12 16 0 1 4 14 10 1 3 6 2 1 7 24
Unique Cell Count 514 148 119 227 290 289 373 402 315 313 335 397 451 727 859 426 261 113 517 159 122 275 469 581
Labelled Cell Count 535 152 124 243 308 353 433 463 386 390 413 517 463 744 885 472 295 129 517 159 122 275 469 581


Cytoplasm, Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.2 7.7 7.5 7.9 7.6 6.5 6.1 6.2 5.9 5.4 5.6 5.4 9.3 8.9 8.8 7.7 8.6 10.0 8.6 8.5 9.4
Std Deviation (1e-4) 0.9 1.1 1.0 1.0 1.3 1.0 0.9 1.2 1.1 1.1 1.2 1.0 1.2 1.1 1.0 1.0 1.3 1.4 1.2 1.4 1.4
Intensity Change (Log2) – – – 0.06 0.01 -0.21 -0.32 -0.29 -0.35 -0.48 -0.43 -0.49 0.3 0.24 0.22 0.04 0.19 0.4 0.19 0.18 0.31

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.9 -0.6 -3.8 -5.3 -6.1 -7.6 -8.6 -9.1 -9.2 1.4 0.2 0.6 -2.3 -2.3 -2.5
Endoplasmic Reticulum 0 0 0 1.9 0 0 2.0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 6.1 5.8 6.9 8.9 10.3 10.9 12.1 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.4908 4.9257 4.3481 3.5432 3.5871 4.5198 2.9397 4.6158 4.0849 3.5192 3.5119 4.1227 5.7172 7.319 6.372 6.4011 5.9392 6.6236
Actin 0.0118 0.0012 0.006 0.0184 0.0014 0.0118 0.0301 0.0016 0.0235 0.0218 0 0.0105 0.0211 0.0004 0.0083 0.0034 0.014 0.0054
Bud 0.0041 0.0035 0.0023 0.0025 0.0005 0.001 0.0008 0.0002 0.0012 0.0016 0 0.0002 0.0058 0.0094 0.0127 0.0048 0.0014 0.0033
Bud Neck 0.0006 0.0003 0.0018 0.0022 0.0006 0.0016 0.0016 0.0001 0.0023 0.0026 0.0002 0.0007 0.0016 0.0002 0.0009 0.0003 0.0005 0.0007
Bud Periphery 0.0033 0.0011 0.002 0.0009 0.0005 0.0007 0.0008 0.0001 0.0006 0.0036 0 0.0001 0.0016 0.0014 0.0043 0.0024 0.0008 0.0019
Bud Site 0.0017 0.0133 0.007 0.0024 0.0013 0.0002 0.0344 0.0007 0.0029 0.0097 0 0.0001 0.0056 0.0033 0.0097 0.0022 0.0008 0.0002
Cell Periphery 0.0015 0.001 0.0005 0.0003 0.0002 0.0001 0.0006 0.0002 0.0002 0.0018 0 0.0001 0.0007 0.0002 0.0007 0.0001 0.0002 0.0001
Cytoplasm 0.8415 0.9378 0.8915 0.7824 0.81 0.8906 0.5606 0.9368 0.8225 0.785 0.9717 0.9219 0.82 0.9542 0.8804 0.9288 0.8413 0.9255
Cytoplasmic Foci 0.0209 0.0085 0.0188 0.0444 0.019 0.0219 0.0882 0.0049 0.0537 0.0274 0.0058 0.0092 0.0235 0.0076 0.0176 0.0117 0.0231 0.0143
Eisosomes 0.0001 0 0.0001 0.0004 0.0001 0 0.0003 0 0.0001 0.0005 0 0.0003 0.0001 0 0 0 0.0002 0
Endoplasmic Reticulum 0.0193 0.0079 0.0139 0.0128 0.0167 0.0216 0.0233 0.0043 0.0084 0.0061 0.0057 0.0106 0.0157 0.0007 0.0112 0.0057 0.0054 0.0063
Endosome 0.0288 0.0131 0.0168 0.0472 0.0471 0.0252 0.0894 0.0056 0.0273 0.0583 0.0106 0.0136 0.033 0.0065 0.0139 0.0149 0.0138 0.0118
Golgi 0.0056 0.0012 0.0029 0.025 0.0055 0.0011 0.0284 0.0015 0.0143 0.0186 0.0002 0.0017 0.0074 0.0005 0.0087 0.0012 0.0064 0.0028
Lipid Particles 0.0048 0.0002 0.001 0.0215 0.0045 0.0003 0.0374 0.0001 0.005 0.003 0 0.0009 0.0022 0.0001 0.0007 0.0002 0.0075 0.0005
Mitochondria 0.0045 0.0006 0.0024 0.0039 0.0219 0.0015 0.0063 0.0003 0.005 0.0329 0.0001 0.0013 0.0026 0.0017 0.0094 0.0006 0.0547 0.0012
None 0.0316 0.0045 0.0202 0.0085 0.0267 0.0142 0.0438 0.0419 0.0093 0.0021 0.0028 0.0177 0.0375 0.0085 0.0067 0.0132 0.0126 0.0194
Nuclear Periphery 0.0026 0.0009 0.0021 0.0034 0.0057 0.0014 0.0095 0.0004 0.0045 0.001 0.0006 0.0008 0.0061 0.0002 0.0012 0.0019 0.0035 0.0005
Nucleolus 0.0008 0.0001 0.0003 0.0008 0.0043 0.0003 0.0006 0 0.0006 0.001 0 0.0001 0.0004 0.0016 0.0002 0.0001 0.0004 0.0001
Nucleus 0.0033 0.0013 0.002 0.0049 0.0052 0.0016 0.0026 0.0004 0.0027 0.0017 0.0004 0.0006 0.005 0.0013 0.0049 0.0017 0.0014 0.0009
Peroxisomes 0.0058 0.0001 0.0008 0.0047 0.0009 0.0003 0.0202 0 0.0031 0.001 0 0.0081 0.0016 0.0002 0.0054 0.0003 0.0058 0.0003
Punctate Nuclear 0.0011 0.0003 0.0014 0.0066 0.0215 0.001 0.0147 0.0001 0.0104 0.0008 0 0.0004 0.0048 0.0012 0.0007 0.0044 0.0029 0.0038
Vacuole 0.0052 0.0027 0.0056 0.0051 0.0044 0.0025 0.0043 0.0007 0.0015 0.0176 0.0015 0.0008 0.0028 0.0008 0.0019 0.0016 0.0024 0.0008
Vacuole Periphery 0.0012 0.0005 0.0007 0.0017 0.0019 0.0011 0.002 0.0001 0.0009 0.0017 0.0003 0.0004 0.0009 0.0002 0.0005 0.0004 0.001 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 22.0842 30.8691 26.1024 28.9674 34.3597 39.3282 28.4898 31.5987 30.0477 33.1311
Translational Efficiency 1.4042 1.0443 0.943 0.9486 0.6683 0.8043 1.0558 0.8169 0.7487 0.9354

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1057 1358 2825 1350 662 863 2226 1945 1719 2221 5051 3295

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 810.14 913.77 1101.44 985.85 954.08 954.03 1099.60 1093.65 865.57 929.41 1100.63 1049.48
Standard Deviation 93.08 159.65 135.12 167.98 120.25 132.94 121.81 131.95 125.70 151.12 129.43 157.00
Intensity Change Log 2 — 0.173660 0.443148 0.283197 — -0.000076 0.204797 0.196969 — 0.082310 0.319155 0.237206

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000270 0.000221 0.000186 0.000366 0.000452 0.000640 0.000330 0.001152 0.000340 0.000384 0.000250 0.000830
Bud Neck 0.002696 0.001874 0.001621 0.003579 0.001411 0.003907 0.001236 0.004981 0.002201 0.002664 0.001451 0.004407
Bud Site 0.020777 0.021355 0.009327 0.031991 0.018137 0.043603 0.011849 0.023645 0.019760 0.030000 0.010438 0.027064
Cell Periphery 0.000310 0.000119 0.000058 0.000083 0.000291 0.000158 0.000071 0.000088 0.000303 0.000134 0.000063 0.000086
Cytoplasm 0.579875 0.701521 0.854500 0.668508 0.603904 0.548713 0.793267 0.589232 0.589129 0.642145 0.827514 0.621712
Cytoplasmic Foci 0.286494 0.159564 0.049099 0.091757 0.263220 0.278966 0.073809 0.074110 0.277531 0.205959 0.059989 0.081340
Eisosomes 0.000049 0.000013 0.000005 0.000012 0.000033 0.000041 0.000007 0.000015 0.000043 0.000023 0.000006 0.000014
Endoplasmic Reticulum 0.010789 0.003974 0.000615 0.000471 0.011114 0.002169 0.000684 0.000819 0.010914 0.003273 0.000646 0.000677
Endosome 0.009798 0.014792 0.003076 0.011197 0.018495 0.024763 0.006433 0.015767 0.013147 0.018666 0.004555 0.013895
Golgi 0.018761 0.008944 0.001141 0.004337 0.013214 0.017106 0.001913 0.002754 0.016625 0.012116 0.001481 0.003402
Lipid Particles 0.004807 0.002233 0.001495 0.001169 0.003539 0.001766 0.001592 0.001555 0.004319 0.002051 0.001538 0.001397
Mitochondria 0.015527 0.000830 0.000199 0.000874 0.003240 0.001960 0.000173 0.000965 0.010795 0.001269 0.000187 0.000928
Mitotic Spindle 0.003207 0.001088 0.002071 0.017612 0.001037 0.002263 0.003122 0.032481 0.002371 0.001544 0.002534 0.026389
None 0.002980 0.002717 0.000650 0.001408 0.002129 0.000292 0.000284 0.000672 0.002652 0.001774 0.000488 0.000974
Nuclear Periphery 0.000132 0.000185 0.000077 0.000274 0.000129 0.000050 0.000071 0.000643 0.000130 0.000132 0.000074 0.000492
Nuclear Periphery Foci 0.000621 0.001636 0.001454 0.004120 0.001515 0.000486 0.001474 0.001898 0.000965 0.001189 0.001462 0.002808
Nucleolus 0.000309 0.000450 0.000154 0.000516 0.000188 0.000228 0.000169 0.000605 0.000262 0.000364 0.000161 0.000569
Nucleus 0.012736 0.010404 0.022641 0.016974 0.007889 0.004326 0.012660 0.018783 0.010870 0.008042 0.018243 0.018041
Peroxisomes 0.001517 0.000892 0.000659 0.005178 0.000846 0.003542 0.000634 0.003926 0.001259 0.001922 0.000648 0.004439
Vacuole 0.014120 0.060151 0.050345 0.138423 0.035877 0.057884 0.089073 0.223478 0.022499 0.059270 0.067412 0.188630
Vacuole Periphery 0.014226 0.007038 0.000629 0.001153 0.013340 0.007138 0.001148 0.002431 0.013885 0.007077 0.000858 0.001908

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.26 2.39 -2.04 -3.60 -3.60 -2.03 1.64 -0.99 -0.25 -1.47 -1.14 2.26 -1.42 -1.10 -1.96
Bud Neck 1.62 1.85 -1.55 -4.48 -4.88 -4.14 0.59 -5.89 -0.80 -6.13 -1.18 2.02 -4.37 -3.52 -7.38
Bud Site -0.26 7.56 -1.30 -1.05 -7.18 -8.67 4.80 -0.38 8.05 -4.48 -5.95 8.82 -0.75 4.90 -8.37
Cell Periphery 8.89 12.43 11.83 5.93 -1.17 4.56 9.01 7.78 4.11 0.19 9.71 15.31 13.04 5.60 -0.20
Cytoplasm -11.51 -31.11 -2.81 8.41 26.55 3.87 -15.11 2.83 -1.65 24.08 -6.24 -32.78 0.33 7.03 37.52
Cytoplasmic Foci 16.57 38.00 30.60 13.88 -7.96 -1.47 24.84 25.86 27.96 2.50 11.42 44.86 41.31 28.96 -4.34
Eisosomes 13.74 17.30 14.17 0.08 -12.18 -1.11 5.56 4.26 5.35 -7.50 6.16 15.45 12.43 5.03 -12.99
Endoplasmic Reticulum 5.00 8.27 8.53 5.99 1.51 5.16 6.26 6.31 3.58 0.72 7.14 10.37 10.55 6.84 1.36
Endosome -4.38 9.86 1.21 5.22 -7.52 -3.09 9.37 4.70 7.54 -5.35 -5.22 13.05 3.41 8.21 -9.14
Golgi 10.39 22.64 14.69 6.80 -1.51 -2.58 13.42 12.92 12.23 0.10 5.56 25.98 21.20 14.57 -1.42
Lipid Particles 6.42 8.54 9.06 3.71 1.40 4.31 5.26 5.30 0.92 1.12 7.72 10.02 10.03 2.99 1.50
Mitochondria 8.52 8.91 8.70 1.65 -1.49 0.94 2.47 2.10 2.52 -2.28 8.01 9.07 8.71 2.92 -2.67
Mitotic Spindle 2.45 0.77 -6.01 -7.13 -6.51 -1.86 -3.67 -9.68 -8.99 -8.22 1.39 -1.21 -10.96 -11.62 -10.62
None 0.39 6.37 4.15 2.44 -1.15 1.89 1.88 1.55 -3.51 -4.14 1.53 4.95 4.12 2.44 -2.09
Nuclear Periphery -0.89 1.65 -3.79 -2.04 -4.54 3.19 0.88 -3.46 -4.16 -3.68 -0.01 1.81 -4.44 -4.08 -4.86
Nuclear Periphery Foci -5.49 -6.43 -4.32 -2.77 -2.77 5.31 -1.10 -0.44 -3.59 0.42 -1.68 -4.96 -4.29 -3.58 -1.98
Nucleolus -1.16 1.46 -0.87 0.04 -2.20 -0.38 0.20 -2.78 -1.99 -2.99 -1.18 1.45 -2.30 -1.33 -3.73
Nucleus 2.19 -13.88 -6.32 -7.56 4.70 5.10 -7.94 -13.37 -20.28 -7.65 4.20 -15.32 -13.21 -16.31 -0.00
Peroxisomes 2.70 3.71 -4.00 -5.32 -5.72 -3.71 1.72 -5.35 0.78 -6.22 -2.09 4.10 -5.95 -3.39 -8.39
Vacuole -14.99 -24.73 -32.56 -22.99 -24.47 -5.06 -18.54 -36.17 -31.28 -23.84 -14.56 -29.48 -50.45 -38.94 -35.68
Vacuole Periphery 5.76 11.88 11.78 12.16 -0.77 3.42 7.23 6.88 8.05 -1.50 6.57 13.61 13.04 13.58 -2.01
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein involved in assembly of the RNA polymerase III (Pol III) complex; high copy suppressor of Pol III assembly mutation and psk1 psk2 mutations that confer temperature-sensitivity for galactose utilization; physically interacts with Pol III; proposed to bind single-stranded nucleic acids via its R3H domain
Localization
Cell Percentages cytoplasm (96%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-5

Rbs1

Rbs1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rbs1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available