Standard name
Human Ortholog
Description Alpha subunit of COPI vesicle coatomer complex; complex surrounds transport vesicles in the early secretory pathway
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.12 0.16 0.07 0.07 0.09 0.08 0.09 0.1 – 0.05 0.07 0.06 0.11 0.12 0.08 0.17 0.09 – 0 0 0.05 0 0.05 0.06
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Cytoplasm 0 0.05 0 0 0 0 0 0 – 0 0 0 0 0 0.11 0.05 0 – 0 0 0 0 0 0
Endoplasmic Reticulum 0 0.1 0 0 0 0 0 0 – 0 0 0 0.07 0.08 0.06 0 0 – 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Golgi 0.9 0.63 0.64 0.58 0.76 0.31 0.31 0.3 – 0.21 0.14 0.16 0.86 0.86 0.79 0.9 0.85 – 0.9 0.76 0.85 0.85 0.86 0.87
Mitochondria 0.35 0.5 0.58 0.81 0.53 0.84 0.86 0.85 – 0.86 0.91 0.91 0.1 0.11 0 0.07 0.13 – 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0.05 0.05 – 0.09 0.09 0.09 0 0 0 0 0.05 – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Vac/Vac Membrane 0.14 0.12 0.08 0 0.1 0 0 0 – 0.06 0 0 0.17 0.18 0.24 0.12 0.16 – 0 0.12 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 67 52 24 13 31 21 28 25 – 15 18 24 26 27 19 7 9 – 13 11 16 7 15 21
Bud 3 3 5 1 2 2 1 4 – 4 7 10 2 2 0 0 0 – 1 2 2 0 1 3
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 1 0 – 1 1 0 0 0 0 0 0 – – – – – – –
Cell Periphery 0 1 1 0 0 1 0 1 – 0 1 1 0 0 0 0 0 – 0 0 0 0 0 0
Cytoplasm 13 15 12 3 10 7 10 8 – 6 5 7 9 9 26 2 4 – 1 7 1 0 0 1
Endoplasmic Reticulum 16 32 12 4 4 8 8 8 – 3 5 5 16 18 14 1 4 – 1 3 2 0 1 2
Endosome 0 2 1 0 1 0 1 0 – 0 1 0 0 0 1 0 0 – 5 11 7 8 3 3
Golgi 497 201 205 110 250 79 92 77 – 64 38 66 199 196 194 36 86 – 537 300 291 236 242 329
Mitochondria 194 161 186 153 173 212 254 217 – 265 245 363 24 24 10 3 13 – 13 9 8 8 6 6
Nucleus 0 2 0 0 0 1 1 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 1 – 2 2 5 0 0 0 0 0 – 1 0 0 0 0 0
Nucleolus 13 4 5 4 5 7 15 14 – 27 23 35 2 2 3 0 5 – 1 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 1 0 0 0 0 0 – 1 0 0 1 1 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 1 0 0 0
Vac/Vac Membrane 77 40 27 6 34 10 13 9 – 19 6 15 40 41 60 5 16 – 17 46 4 11 7 3
Unique Cell Count 555 320 322 190 329 251 296 255 307 268 401 231 228 247 40 101 599 398 342 277 283 377
Labelled Cell Count 880 513 478 294 510 348 424 364 406 352 532 318 319 327 54 137 599 398 342 277 283 377


Early Golgi, Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 34.0 30.0 26.2 24.4 25.6 24.3 24.9 24.7 – 24.1 22.8 22.9 32.5 32.5 32.8 25.0 28.5 – 31.0 33.2 35.1
Std Deviation (1e-4) 6.0 8.2 6.3 5.2 5.7 6.1 6.5 6.7 – 6.0 6.4 6.1 7.9 7.9 9.5 5.7 9.7 – 6.4 9.6 7.1
Intensity Change (Log2) – – – -0.1 -0.03 -0.11 -0.07 -0.08 – -0.12 -0.2 -0.19 0.31 0.31 0.33 -0.07 0.12 – 0.24 0.34 0.42

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP700010203040WT3HU80HU120HU160010203040WT3rpd3Δ_1rpd3Δ_2010203040WT1AF100AF140AF180010203040
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.3 0.9 0.4 0.9 1.0 – -1.3 -0.3 -0.8 1.5 1.7 0.1 0 0.5 –
Bud 0 0 0 0 0 – 0 0.9 0.9 0 0 0 0 0 –
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 –
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 –
Cell Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 –
Cytoplasm -1.4 -0.5 -0.6 -0.2 -0.4 – -1.3 -1.3 -1.7 0.1 0.1 3.2 0 0 –
Endoplasmic Reticulum -1.0 -2.1 -0.3 -0.7 -0.4 – -2.3 -1.3 -2.2 1.7 2.1 1.1 0 0 –
Endosome 0 0 0 0 0 – 0 0 0 0 0 0 0 0 –
Golgi -1.3 3.4 -7.6 -8.1 -8.0 – -10.8 -12.2 -13.0 5.9 5.8 3.8 3.3 4.1 –
Mitochondria 5.3 -1.3 6.9 7.7 7.1 – 7.9 9.2 10.2 -11.3 -11.2 -13.4 -6.0 -7.9 –
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 –
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 –
Nucleolus 0 0 1.0 2.5 2.6 – 4.1 4.0 4.2 0 0 0 0 0 –
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 –
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 –
Vacuole -2.3 0.9 -2.1 -2.0 -2.4 – -1.1 -3.2 -2.7 3.2 3.4 5.2 0 2.2 –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 24.5511 32.3995 30.975 29.9604 30.6707 31.2572 25.7041 33.4544 30.215 32.6029 28.9145 32.6361 27.3391 36.9467 34.2823 34.4152 31.5688 34.8757
Actin 0.0304 0.0092 0.0072 0.0149 0.0007 0.0036 0.0225 0.0102 0.0481 0.0029 0.0668 0.0021 0.0768 0.0142 0.0328 0.0242 0.0266 0.0019
Bud 0.0005 0.0008 0.0009 0.0004 0.0003 0.0001 0.0007 0.0005 0.0004 0 0.0002 0 0.0003 0.007 0.0005 0.0003 0.0003 0
Bud Neck 0.0009 0.0004 0.0002 0.0006 0.0002 0.0001 0.0025 0.0003 0.0007 0.0001 0.0003 0.0001 0.0005 0.0005 0.0002 0.0002 0.0002 0.0001
Bud Periphery 0.0006 0.0004 0.0014 0.0005 0.0004 0.0001 0.0012 0.0003 0.0006 0.0001 0.0004 0 0.0005 0.0107 0.0008 0.0007 0.0004 0.0001
Bud Site 0.0011 0.006 0.0005 0.0011 0.0001 0.0001 0.0043 0.0026 0.0009 0 0.0017 0 0.001 0.004 0.0008 0.0002 0.0002 0
Cell Periphery 0.0006 0.001 0.0008 0.0007 0.0009 0.0001 0.0006 0.0005 0.0005 0.0002 0.0001 0 0.0004 0.001 0.0004 0.0006 0.0002 0.0001
Cytoplasm 0.0081 0.0049 0.0045 0.0014 0.0014 0.0019 0.0023 0.0159 0.0038 0.0003 0.0003 0.0002 0.0013 0.0015 0.0006 0.0003 0.0005 0.0001
Cytoplasmic Foci 0.0265 0.017 0.0124 0.0136 0.0089 0.0098 0.0187 0.0132 0.0109 0.0043 0.0045 0.0032 0.0307 0.0087 0.0072 0.0049 0.0056 0.0026
Eisosomes 0.0007 0.0003 0.0001 0.0004 0 0.0001 0.0004 0.0001 0.0005 0.0002 0.0002 0 0.0013 0.0004 0.0002 0.001 0.0002 0.0001
Endoplasmic Reticulum 0.004 0.0014 0.0016 0.0011 0.0008 0.001 0.0035 0.0027 0.0048 0.0007 0.0012 0.0003 0.0013 0.001 0.001 0.001 0.0011 0.0005
Endosome 0.1036 0.1543 0.1441 0.228 0.1832 0.0782 0.1107 0.1152 0.1094 0.1709 0.0923 0.0477 0.1225 0.112 0.0733 0.0986 0.1369 0.048
Golgi 0.5416 0.6598 0.6649 0.6532 0.5292 0.8129 0.6026 0.6917 0.6652 0.6303 0.7188 0.9109 0.6341 0.7571 0.6853 0.7908 0.6615 0.8529
Lipid Particles 0.0231 0.0228 0.0178 0.0112 0.0398 0.0057 0.0362 0.003 0.0096 0.0013 0.003 0.0009 0.0084 0.0025 0.0196 0.0024 0.0216 0.007
Mitochondria 0.1722 0.046 0.0669 0.0296 0.0155 0.05 0.1193 0.0962 0.0821 0.0796 0.0414 0.0184 0.0842 0.0285 0.0924 0.0172 0.1234 0.0656
None 0.0062 0.0001 0.0018 0.0001 0 0.0013 0.0047 0.0002 0.0031 0 0.0002 0 0.0011 0.0001 0.0009 0 0.0001 0
Nuclear Periphery 0.0146 0.001 0.0035 0.0005 0.0014 0.0076 0.0131 0.005 0.004 0.0006 0.0358 0.0003 0.0012 0.001 0.0023 0.0004 0.0005 0.0008
Nucleolus 0.0021 0.0037 0.0045 0.0001 0.001 0.0005 0.002 0.001 0.0002 0 0.0001 0 0.0004 0.0003 0.0002 0.0001 0 0.0001
Nucleus 0.01 0.0007 0.0023 0.0001 0.0008 0.0037 0.0036 0.0013 0.0006 0.0001 0.0008 0 0.0004 0.0006 0.0003 0.0001 0.0001 0.0001
Peroxisomes 0.0073 0.0006 0.0005 0.0032 0.0002 0.0001 0.0028 0.0005 0.0049 0 0.0012 0 0.0009 0.0002 0.0022 0.0001 0.0002 0.0001
Punctate Nuclear 0.0192 0.0001 0.0017 0.0001 0 0.0044 0.0067 0.0012 0.0009 0 0.0002 0 0.0122 0 0.0007 0 0 0
Vacuole 0.0087 0.0241 0.0179 0.0136 0.0674 0.0033 0.01 0.0109 0.0119 0.0167 0.0028 0.0041 0.0044 0.0184 0.0156 0.0163 0.0049 0.0032
Vacuole Periphery 0.018 0.0454 0.0448 0.0254 0.1479 0.0155 0.0316 0.0275 0.0368 0.0918 0.0279 0.0118 0.0161 0.0306 0.0626 0.0405 0.0155 0.0166

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 227.6575 202.1442 185.9266 208.585 191.4227 194.5027 203.7655 201.2286 192.248 225.7676
Translational Efficiency 0.6167 0.6744 0.6405 0.5836 0.5629 0.6537 0.675 0.5124 0.5686 0.5101

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1451 1268 221 1021 1031 1721 2892 2330 2482 2989 3113 3351

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 2276.66 2183.27 3499.99 3087.22 1524.63 1962.63 3008.78 3148.32 1964.27 2056.23 3043.65 3129.70
Standard Deviation 387.98 438.40 475.39 697.55 364.24 377.75 464.14 586.86 529.58 419.03 481.76 623.31
Intensity Change Log 2 — -0.060428 0.620432 0.439389 — 0.364329 0.980719 1.046123 — 0.125196 0.775896 0.714025

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.003056 0.006582 0.015180 0.007170 0.005387 0.002139 0.001175 0.001048 0.004024 0.004024 0.002169 0.002913
Bud Neck 0.000433 0.000576 0.010669 0.001668 0.000442 0.000305 0.000163 0.000162 0.000437 0.000420 0.000909 0.000620
Bud Site 0.001039 0.001012 0.002623 0.007469 0.002387 0.000481 0.000467 0.000648 0.001599 0.000706 0.000620 0.002726
Cell Periphery 0.000375 0.000290 0.001392 0.007356 0.000483 0.000174 0.000354 0.000424 0.000420 0.000223 0.000428 0.002536
Cytoplasm 0.000110 0.000407 0.000109 0.001089 0.000693 0.000768 0.000097 0.000266 0.000352 0.000615 0.000097 0.000517
Cytoplasmic Foci 0.006576 0.018766 0.013886 0.012338 0.026902 0.031798 0.006742 0.009001 0.015019 0.026269 0.007250 0.010018
Eisosomes 0.000138 0.000273 0.000523 0.000293 0.000150 0.000076 0.000063 0.000031 0.000143 0.000160 0.000096 0.000111
Endoplasmic Reticulum 0.002330 0.002675 0.003981 0.011542 0.004954 0.001346 0.001868 0.001155 0.003420 0.001910 0.002018 0.004320
Endosome 0.009652 0.010738 0.015301 0.018685 0.017693 0.020720 0.005460 0.012742 0.012992 0.016485 0.006158 0.014553
Golgi 0.866902 0.849722 0.624889 0.773378 0.813095 0.832772 0.910469 0.884713 0.844551 0.839962 0.890195 0.850791
Lipid Particles 0.011279 0.027626 0.082097 0.038192 0.011475 0.011308 0.009192 0.006759 0.011360 0.018230 0.014368 0.016336
Mitochondria 0.007478 0.030927 0.011545 0.002297 0.069313 0.037843 0.005791 0.004078 0.033164 0.034909 0.006200 0.003535
Mitotic Spindle 0.001253 0.000205 0.002074 0.001095 0.000665 0.000880 0.000063 0.000892 0.001009 0.000593 0.000206 0.000954
None 0.000205 0.000595 0.000796 0.000239 0.000724 0.000407 0.000162 0.000089 0.000420 0.000486 0.000207 0.000135
Nuclear Periphery 0.000398 0.000407 0.006413 0.000486 0.000319 0.000531 0.000252 0.000390 0.000365 0.000478 0.000689 0.000419
Nuclear Periphery Foci 0.001099 0.000509 0.005464 0.001977 0.000447 0.001017 0.000271 0.000796 0.000828 0.000802 0.000640 0.001156
Nucleolus 0.000040 0.000064 0.000192 0.000033 0.000050 0.000159 0.000010 0.000009 0.000044 0.000119 0.000023 0.000016
Nucleus 0.000021 0.000074 0.000108 0.000052 0.000385 0.000343 0.000007 0.000009 0.000172 0.000229 0.000014 0.000022
Peroxisomes 0.000053 0.000103 0.000181 0.000210 0.000240 0.000125 0.000030 0.000025 0.000130 0.000116 0.000041 0.000081
Vacuole 0.022231 0.008460 0.072997 0.059938 0.007335 0.012466 0.006621 0.023310 0.016043 0.010767 0.011333 0.034470
Vacuole Periphery 0.065331 0.039988 0.129580 0.054494 0.036861 0.044344 0.050742 0.053452 0.053505 0.042496 0.056339 0.053770

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.69 -3.35 -2.63 -0.40 2.11 2.79 4.09 4.05 1.52 0.26 0.02 2.57 1.36 1.45 -1.26
Bud Neck -1.25 -6.65 -4.38 -3.91 5.75 1.08 2.44 2.42 1.86 0.00 0.26 -3.37 -1.73 -2.05 1.83
Bud Site 0.08 -3.17 -5.26 -5.13 -3.95 2.65 2.67 2.44 -0.80 -0.87 2.24 2.62 -2.31 -4.75 -5.18
Cell Periphery 1.73 -6.66 -8.30 -8.40 -6.99 4.54 1.62 0.78 -5.84 -1.18 5.13 -0.11 -7.98 -8.76 -7.90
Cytoplasm -1.06 0.22 -3.98 -1.85 -4.01 -0.25 2.56 1.74 1.20 -1.72 -0.98 2.38 -1.27 0.40 -3.92
Cytoplasmic Foci -10.95 -4.07 -4.40 4.03 0.70 -2.69 14.85 12.70 17.45 -4.51 -10.56 10.95 6.07 16.90 -5.15
Eisosomes -2.78 -4.36 -2.24 -0.34 2.36 3.87 6.03 8.48 3.10 4.33 -0.59 1.86 1.06 2.12 -0.80
Endoplasmic Reticulum -0.71 -2.47 -7.37 -7.38 -5.87 5.11 4.38 5.43 1.14 4.38 3.82 3.55 -1.69 -6.10 -5.83
Endosome -1.15 -3.92 -8.05 -6.88 -2.11 -1.94 10.21 3.69 6.57 -10.71 -3.85 10.42 -1.95 2.23 -14.40
Golgi 2.28 12.04 10.25 8.10 -6.97 -2.14 -12.13 -8.51 -8.28 5.90 0.77 -8.69 -1.00 -1.92 8.51
Lipid Particles -6.52 -7.57 -7.74 -2.74 4.44 0.09 1.26 2.56 3.44 2.07 -4.66 -2.10 -3.29 1.10 -1.30
Mitochondria -8.01 -1.67 4.08 10.02 3.93 5.12 11.55 11.83 11.60 1.72 -0.55 10.79 11.90 15.11 3.15
Mitotic Spindle 2.16 -0.93 0.26 -2.88 1.22 -0.48 2.30 -0.55 -0.02 -2.26 1.05 2.61 0.10 -1.00 -2.71
None -9.72 -7.80 -1.68 8.49 7.22 2.69 9.64 10.90 3.39 7.48 -1.15 7.76 10.55 6.11 6.08
Nuclear Periphery -0.11 -5.28 -1.43 -1.48 5.20 -2.22 1.06 -0.67 1.22 -1.54 -1.91 -3.40 -0.75 0.74 2.50
Nuclear Periphery Foci 1.91 -4.14 -2.28 -5.67 3.36 -2.34 2.30 -2.88 0.90 -5.18 0.16 1.06 -1.55 -2.02 -4.11
Nucleolus -0.65 -5.09 0.50 0.96 6.44 -1.23 2.73 2.81 1.69 0.51 -1.39 1.88 2.49 1.93 2.31
Nucleus -1.13 -7.03 -4.31 0.47 4.44 0.11 1.19 1.19 1.21 -1.72 -0.26 1.20 1.14 1.30 -4.21
Peroxisomes -1.65 -3.62 -2.60 -1.69 -0.47 1.70 3.65 3.84 2.72 0.38 0.41 3.20 1.56 1.14 -1.81
Vacuole 8.24 -7.26 -9.59 -13.64 1.56 -3.82 0.69 -9.87 -6.86 -12.12 4.66 4.01 -10.59 -14.85 -14.22
Vacuole Periphery 7.30 -6.70 2.74 -4.29 7.83 -2.45 -4.81 -5.44 -3.31 -1.07 4.61 -1.09 -0.14 -5.31 1.05
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Alpha subunit of COPI vesicle coatomer complex; complex surrounds transport vesicles in the early secretory pathway
Localization
Cell Percentages nucleus (22%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Cop1

Cop1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cop1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available