Standard name | |
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Description | Transcription factor; involved in regulation of cell cycle progression from G1 to S phase, forms a complex with Swi6p that binds to MluI cell cycle box regulatory element in promoters of DNA synthesis genes |
ensLOC | DeepLoc | |||||||||||||||||||||||
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Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
Cortical Patches | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 2 |
Bud | 0 | 0 | 1 | 0 | 1 | 0 | 5 | 2 | 6 | 8 | 3 | 6 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3 | 1 | 4 | 10 |
Bud Neck | 0 | 0 | 2 | 1 | 2 | 3 | 2 | 5 | 1 | 3 | 3 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 4 |
Bud Site | 0 | 0 | 1 | 5 | 2 | 16 | 18 | 6 | 18 | 22 | 25 | 14 | 1 | 0 | 0 | 0 | 0 | 0 | – | – | – | – | – | – |
Cell Periphery | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cytoplasm | 3 | 9 | 12 | 7 | 19 | 20 | 26 | 23 | 11 | 10 | 7 | 9 | 31 | 25 | 37 | 8 | 1 | 3 | 0 | 2 | 2 | 1 | 2 | 2 |
Endoplasmic Reticulum | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 2 | 3 |
Endosome | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 4 | 3 | 0 | 1 | 2 | 2 | 3 | 2 | 3 | 11 | 13 |
Golgi | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3 | 0 | 0 | 1 | 2 |
Mitochondria | 24 | 41 | 20 | 11 | 16 | 101 | 142 | 72 | 200 | 230 | 133 | 73 | 17 | 1 | 7 | 3 | 3 | 5 | 3 | 2 | 3 | 4 | 5 | 4 |
Nucleus | 205 | 221 | 372 | 204 | 308 | 348 | 403 | 352 | 308 | 300 | 190 | 201 | 273 | 210 | 237 | 55 | 49 | 18 | 187 | 222 | 334 | 120 | 159 | 145 |
Nuclear Periphery | 1 | 0 | 3 | 0 | 2 | 8 | 8 | 2 | 6 | 6 | 1 | 2 | 8 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 2 |
Nucleolus | 18 | 5 | 3 | 4 | 6 | 23 | 21 | 22 | 48 | 49 | 50 | 30 | 29 | 12 | 23 | 1 | 7 | 2 | 18 | 16 | 25 | 44 | 55 | 51 |
Peroxisomes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
SpindlePole | 2 | 3 | 28 | 8 | 23 | 8 | 22 | 29 | 10 | 10 | 5 | 6 | 2 | 4 | 2 | 1 | 0 | 0 | 0 | 2 | 7 | 4 | 6 | 14 |
Vac/Vac Membrane | 0 | 5 | 2 | 0 | 5 | 2 | 3 | 3 | 1 | 2 | 0 | 1 | 2 | 4 | 6 | 4 | 3 | 1 | 7 | 7 | 24 | 20 | 30 | 27 |
Unique Cell Count | 219 | 252 | 392 | 217 | 348 | 413 | 492 | 422 | 397 | 407 | 237 | 255 | 318 | 247 | 297 | 71 | 57 | 25 | 226 | 267 | 411 | 212 | 290 | 299 |
Labelled Cell Count | 253 | 287 | 446 | 240 | 385 | 530 | 651 | 516 | 610 | 640 | 417 | 346 | 365 | 265 | 317 | 75 | 65 | 32 | 226 | 267 | 411 | 212 | 290 | 299 |
Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean Cell GFP Intensity (1e-4) | 5.3 | 5.4 | 5.5 | 5.2 | 5.7 | 4.6 | 4.8 | 5.1 | 4.1 | 3.9 | 3.8 | 4.5 | 5.9 | 6.8 | 5.9 | 7.7 | 8.2 | 7.2 | 6.2 | 5.3 | 5.6 |
Std Deviation (1e-4) | 0.8 | 0.8 | 0.8 | 1.3 | 1.2 | 1.3 | 1.2 | 1.3 | 0.7 | 0.7 | 1.0 | 1.1 | 2.3 | 4.1 | 2.0 | 2.2 | 1.5 | 1.7 | 4.4 | 2.0 | 1.7 |
Intensity Change (Log2) | – | – | – | -0.09 | 0.05 | -0.26 | -0.2 | -0.13 | -0.44 | -0.5 | -0.55 | -0.31 | 0.09 | 0.29 | 0.09 | 0.46 | 0.56 | 0.37 | 0.17 | -0.05 | 0.01 |
Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cortical Patches | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bud | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bud Neck | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bud Site | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cell Periphery | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cytoplasm | 0.1 | 1.6 | 1.3 | 1.6 | 1.7 | -0.2 | -0.5 | -0.1 | 0.3 | 3.7 | 3.7 | 4.8 | 0 | 0 | 0 |
Endoplasmic Reticulum | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endosome | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Golgi | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mitochondria | 0 | -0.3 | 0 | 0 | 5.4 | 0 | 0 | 0 | 0 | 0.1 | -3.2 | -1.8 | 0 | 0 | 0 |
Nucleus | -0.5 | -3.2 | -4.9 | -5.8 | -5.2 | -7.0 | -8.2 | -5.8 | -6.3 | -4.2 | -4.3 | -6.1 | -5.0 | -2.6 | -4.5 |
Nuclear Periphery | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nucleolus | 0 | 0 | 0 | 0 | 3.7 | 0 | 0 | 0 | 0 | 5.3 | 3.3 | 4.8 | 0 | 0 | 0 |
Peroxisomes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
SpindlePole | -1.7 | -0.3 | 0 | 0 | -0.2 | 0 | 0 | 0 | 0 | -4.3 | -3.1 | -4.1 | 0 | 0 | 0 |
Vacuole | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |