Standard name
Description Protein required for DNA repair; component of the Mre11 complex, which is involved in double strand breaks, meiotic recombination, telomere maintenance, and checkpoint signaling

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.05 0.14 0.32 0.22 0.26 0.23 0.24 0.29 0.15 0.16 0.23 0.09 0.16 0.19 0.16 0.12 0.13 0.05 0.09 0.1 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.34 0.54 0 0.22 0.08 0.31 0.43 0.3 0.67 0.7 0.5 0.13 0.05 0.05 0.06 0 0.07 0 0 0 0 0 0.05
Nucleus 0.73 0.51 0.6 0.58 0.63 0.51 0.51 0.47 0.45 0.45 0.48 0.78 0.74 0.67 0.67 0.73 0.68 0.68 0.62 0.49 0.57 0.41 0.45
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.1 0.17 0 0 0 0.05 0 0.05 0 0 0 0.05 0.05 0.08 0.17 0.18 0.17 0.16 0.15 0.26 0.28 0.37 0.32
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 1 3 1
Bud 1 0 0 1 1 2 5 8 11 10 12 0 0 1 1 0 1 0 1 3 7 10 16
Bud Neck 0 0 13 3 8 1 7 7 4 9 8 0 0 0 0 0 0 0 0 1 0 6 5
Bud Site 0 0 0 1 0 3 8 6 10 9 9 0 1 1 0 0 0
Cell Periphery 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0
Cytoplasm 7 12 66 42 77 76 99 116 41 61 72 31 58 86 90 47 40 7 10 26 5 19 18
Endoplasmic Reticulum 0 0 1 0 2 0 3 0 1 0 0 4 1 1 22 11 10 0 0 3 1 3 4
Endosome 0 0 0 5 1 4 2 1 4 0 2 4 11 20 7 8 14 1 3 2 1 5 4
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 2 0 1 0 1 1
Mitochondria 43 47 4 42 25 100 177 122 186 265 158 43 18 24 35 2 20 1 2 7 1 18 21
Nucleus 93 44 124 111 188 166 211 193 126 170 153 257 269 311 369 273 205 102 70 132 105 190 205
Nuclear Periphery 0 0 0 0 0 0 0 1 2 0 0 0 0 1 0 0 0 0 1 1 0 0 0
Nucleolus 1 1 1 0 0 0 0 0 0 0 0 5 0 2 2 0 1 0 0 0 0 8 4
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 1 3 0 0 1 0 0 0 0 0 0
SpindlePole 0 0 3 8 12 8 12 23 2 3 10 0 6 4 4 0 1 6 4 8 3 14 17
Vac/Vac Membrane 13 15 9 2 10 17 8 19 12 9 13 18 18 36 95 66 52 25 16 70 51 174 143
Unique Cell Count 128 87 208 190 299 324 414 407 277 376 318 331 363 463 551 376 302 152 114 269 185 468 452
Labelled Cell Count 158 119 221 215 324 377 534 496 399 536 437 362 383 491 626 407 346 152 114 269 185 468 452


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.2 3.8 5.0 4.4 5.0 4.1 4.1 4.4 3.7 3.4 4.0 4.8 5.0 4.9 6.9 7.2 6.9 5.2 4.5 5.2
Std Deviation (1e-4) 0.6 0.6 1.2 1.4 1.3 1.4 1.0 1.2 1.5 1.2 1.1 1.6 1.7 1.3 1.3 1.6 1.5 9.2 1.7 5.7
Intensity Change (Log2) -0.18 -0.01 -0.3 -0.31 -0.19 -0.45 -0.55 -0.33 -0.07 -0.01 -0.04 0.46 0.51 0.46 0.05 -0.16 0.05


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin
Bud 0 0 0
Bud Neck 0 0 0
Bud Site 0 0 0
Cell Periphery 0 0 0
Cyto
Endoplasmic Reticulum 0 0 0
Endosome 0 0 0
Golgi 0 0 0
Mitochondria 0 0 0
Nuclear Periphery 0 0 0
Nuc
Nucleolus 0 0 0
Peroxisomes 0 0 0
SpindlePole 0 0 0
Vac
Cortical Patches 0 0 0
Cytoplasm 0 0 0
Nucleus 0 0 0
Vacuole 4.6 4.6 4.4


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Xrs2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available