Standard name
Human Ortholog
Description mRNA 5'-end-capping quality-control protein; has distributive, 5'-3' exoRNase activity; similar to Rai1p;
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.0 0.96 0.97 0.98 0.96 0.86 0.79 0.77 0.74 0.72 0.66 0.68 0.98 0.98 0.99 0.96 0.95 0.94 0.85 0.9 0.84 0.82 0.81 0.75
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.06 0.07 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.06 0 0.09 0.12 0.14 0.38 0.44 0.4 0.53 0.5 0.55 0.54 0 0 0 0.09 0.06 0 0.07 0 0.07 0.05 0.05 0.09
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 1 4
Bud 0 0 0 0 2 12 12 15 14 4 22 18 0 0 0 0 1 0 0 0 2 3 7 5
Bud Neck 0 0 1 0 0 3 6 6 1 4 3 6 2 1 0 1 1 0 0 0 0 1 1 2
Bud Site 0 0 0 0 0 0 0 2 0 1 4 2 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 1 0 2 1 2 6 1 3 1 1 0 0 5 1 2 4 0 0 1 0 1 2
Cytoplasm 17 102 254 228 354 391 501 518 301 321 225 314 276 303 469 172 130 100 41 102 216 167 243 232
Endoplasmic Reticulum 0 2 0 0 0 1 1 1 0 0 1 3 1 2 3 12 8 7 0 0 0 3 2 5
Endosome 0 0 0 0 0 0 0 2 0 0 0 0 2 2 1 2 2 0 0 1 3 2 1 3
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 1 2 24 29 52 172 275 272 215 220 185 251 0 0 0 16 8 4 3 4 16 9 15 27
Nucleus 0 0 0 1 1 2 0 6 3 2 3 2 1 0 0 2 0 0 0 0 0 1 1 0
Nuclear Periphery 0 1 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0
Nucleolus 0 0 0 1 1 1 2 4 2 2 1 1 0 1 0 0 1 1 0 0 0 0 2 0
Peroxisomes 0 0 0 0 1 0 0 2 1 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0
SpindlePole 0 0 1 1 2 5 6 5 6 11 8 9 0 0 1 0 3 0 2 0 3 2 2 2
Vac/Vac Membrane 0 0 0 1 1 1 2 1 4 1 0 3 2 1 2 2 0 2 0 0 2 5 10 15
Unique Cell Count 17 106 263 232 367 453 631 672 406 443 339 464 282 308 474 180 137 106 49 113 257 205 301 310
Labelled Cell Count 18 107 281 261 416 590 807 840 548 570 453 610 284 311 481 209 156 119 49 113 257 205 301 310


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.1 4.3 3.5 3.4 3.5 3.2 2.6 3.0 2.7 2.8 2.7 2.8 5.4 5.4 5.4 5.0 5.1 5.2 6.1 6.1 5.9
Std Deviation (1e-4) 0.3 0.7 0.8 1.2 1.5 1.2 1.1 1.4 1.3 1.4 1.2 1.4 1.4 1.8 1.6 1.4 1.1 1.3 2.3 2.1 1.8
Intensity Change (Log2) – – – -0.02 0.01 -0.1 -0.39 -0.22 -0.34 -0.32 -0.35 -0.31 0.64 0.63 0.64 0.53 0.55 0.58 0.83 0.81 0.77

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.0008 0.0004 0.0012 0.0006 0.0005 0.0003 0.0145 0.0011 0.0013 0.0013 0.014 0.0036 0.0035 0.0001 0.0002 0.002 0 0.0872
Bud 0.0064 0.0082 0.0072 0.0095 0.0001 0.0072 0.0011 0.0009 0.0007 0.0002 0.0009 0.0003 0.0001 0.0002 0 0.0002 0 0.0005
Bud Neck 0.0003 0.0003 0.0003 0.0008 0.0003 0.0008 0.012 0.0001 0.0002 0.0002 0.0003 0.0005 0.0003 0 0 0.0005 0 0.0006
Bud Periphery 0.0026 0.0018 0.0022 0.0064 0.0001 0.0022 0.0027 0.0012 0.0016 0.0002 0.0017 0.0005 0.0002 0.0001 0 0.0002 0 0.0004
Bud Site 0.0063 0.0065 0.0069 0.0167 0.0001 0.0003 0.0039 0.0021 0.0041 0.0001 0.0013 0.0004 0.0009 0.0002 0.0001 0.0006 0 0.0007
Cell Periphery 0.0004 0.0004 0.0003 0.0003 0.0001 0.0002 0.0005 0.0005 0.0017 0.0003 0.0001 0.0001 0.0005 0.0001 0.0001 0.0003 0 0.0001
Cytoplasm 0.15 0.2037 0.2024 0.1646 0.2989 0.2431 0.1848 0.3389 0.2573 0.3773 0.3276 0.2325 0.2172 0.3573 0.4735 0.3119 0.0336 0.1799
Cytoplasmic Foci 0.0116 0.01 0.0133 0.0181 0.008 0.0091 0.0184 0.0145 0.01 0.0108 0.0127 0.0095 0.0142 0.0023 0.0037 0.052 0.0004 0.0309
Eisosomes 0.0003 0.0002 0.0002 0.0001 0.0014 0 0.0006 0.0001 0.0008 0.0001 0.0002 0.0001 0.0027 0 0 0.0001 0 0.0001
Endoplasmic Reticulum 0.0014 0.0009 0.0009 0.0007 0.001 0.0006 0.004 0.0028 0.0015 0.0013 0.0012 0.0014 0.0135 0.0008 0.0013 0.0315 0.0001 0.0013
Endosome 0.0021 0.0035 0.005 0.0036 0.0048 0.002 0.0125 0.0108 0.0061 0.0041 0.0131 0.0086 0.0075 0.0005 0.0009 0.1803 0 0.0626
Golgi 0.0003 0.0004 0.0004 0.0002 0.0003 0.0001 0.0051 0.0012 0.001 0.0004 0.0112 0.0027 0.0029 0.0001 0.0001 0.0098 0 0.0259
Lipid Particles 0.0008 0.0002 0.0001 0.0006 0.0001 0.0001 0.0049 0.0008 0.0026 0.0001 0.0114 0.0005 0.0452 0 0.0001 0.0233 0 0.0014
Mitochondria 0.0027 0.0009 0.0012 0.0006 0.0006 0.0005 0.0041 0.0012 0.0017 0.0003 0.0253 0.0021 0.031 0.0001 0.0001 0.0073 0 0.0095
None 0.8031 0.7534 0.7472 0.7397 0.6807 0.7272 0.7107 0.6177 0.7016 0.5993 0.5607 0.7329 0.6184 0.6373 0.5179 0.3488 0.9657 0.5873
Nuclear Periphery 0.0004 0.0007 0.0004 0.0013 0.0003 0.0004 0.0021 0.001 0.0008 0.0003 0.0011 0.0008 0.0009 0.0002 0.0003 0.0076 0 0.0004
Nucleolus 0.0017 0.0007 0.0006 0.0023 0.0001 0.0002 0.001 0.0002 0.0004 0.0001 0.0003 0.0001 0.0007 0 0 0.0011 0 0
Nucleus 0.0028 0.0041 0.0026 0.0093 0.001 0.0024 0.0016 0.001 0.0012 0.0006 0.0008 0.0007 0.0006 0.0002 0.0003 0.0036 0 0.0002
Peroxisomes 0.0003 0.0002 0.004 0.0007 0.0002 0.0002 0.0073 0.0002 0.0022 0.0001 0.0119 0.0005 0.0369 0 0 0.0026 0 0.0065
Punctate Nuclear 0.0039 0.0016 0.0027 0.0217 0.0003 0.0019 0.0018 0.0004 0.001 0.0003 0.0014 0.0004 0.0006 0.0001 0.0001 0.0055 0 0.0002
Vacuole 0.0015 0.0017 0.001 0.002 0.001 0.0008 0.0053 0.0028 0.002 0.0022 0.0019 0.0013 0.0019 0.0004 0.0011 0.008 0 0.0032
Vacuole Periphery 0.0002 0.0003 0.0002 0.0003 0.0002 0.0001 0.0012 0.0005 0.0003 0.0003 0.001 0.0003 0.0003 0 0.0001 0.0029 0 0.0011

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 18.2655 13.3595 14.87 17.5288 17.7615 6.6383 16.3219 16.461 14.1446 17.9651
Translational Efficiency 0.6581 0.6105 0.6095 0.461 0.4963 1.3307 0.4962 0.5159 0.543 0.636

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1536 1402 2533 1501 1555 67 2141 1021 3091 1469 4674 2522

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 660.34 679.15 830.83 738.28 649.28 757.82 881.27 823.75 654.78 682.74 853.93 772.88
Standard Deviation 76.32 97.93 100.07 87.49 97.24 133.48 107.81 106.83 87.64 101.17 106.69 104.58
Intensity Change Log 2 — 0.040521 0.331344 0.160959 — 0.223014 0.440743 0.343366 — 0.133882 0.386619 0.254274

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000205 0.000338 0.000056 0.000111 0.000103 0.000249 0.000247 0.000632 0.000153 0.000334 0.000144 0.000322
Bud Neck 0.038422 0.012850 0.005103 0.003922 0.007502 0.079791 0.004674 0.007716 0.022867 0.015903 0.004906 0.005458
Bud Site 0.007976 0.016148 0.005964 0.011110 0.002821 0.029113 0.009710 0.010015 0.005383 0.016739 0.007680 0.010667
Cell Periphery 0.000219 0.000553 0.000061 0.000138 0.000167 0.000211 0.000084 0.000258 0.000193 0.000537 0.000072 0.000186
Cytoplasm 0.431543 0.432069 0.674723 0.605015 0.492732 0.350855 0.558647 0.413543 0.462326 0.428365 0.621553 0.527500
Cytoplasmic Foci 0.296615 0.298100 0.013299 0.050463 0.158484 0.214077 0.009990 0.028555 0.227125 0.294268 0.011784 0.041594
Eisosomes 0.000442 0.000207 0.000015 0.000050 0.000097 0.000216 0.000022 0.000077 0.000269 0.000207 0.000018 0.000061
Endoplasmic Reticulum 0.000444 0.000853 0.000686 0.000888 0.000809 0.000282 0.001662 0.003186 0.000628 0.000827 0.001133 0.001818
Endosome 0.015196 0.013274 0.001344 0.006725 0.004636 0.042250 0.001422 0.008980 0.009883 0.014595 0.001380 0.007638
Golgi 0.004207 0.007993 0.000054 0.000378 0.000632 0.028435 0.000367 0.001639 0.002409 0.008925 0.000197 0.000889
Lipid Particles 0.008408 0.014937 0.000534 0.001528 0.006147 0.006858 0.000637 0.001411 0.007271 0.014568 0.000581 0.001481
Mitochondria 0.009718 0.010076 0.000304 0.000303 0.003731 0.015179 0.000558 0.005325 0.006706 0.010309 0.000420 0.002336
Mitotic Spindle 0.002211 0.003726 0.006141 0.006253 0.000708 0.012963 0.010813 0.010754 0.001455 0.004148 0.008281 0.008075
None 0.001707 0.004554 0.004735 0.003256 0.010812 0.001245 0.005594 0.008888 0.006288 0.004403 0.005128 0.005536
Nuclear Periphery 0.000209 0.000548 0.000957 0.000674 0.000564 0.000153 0.001359 0.001620 0.000388 0.000530 0.001141 0.001057
Nuclear Periphery Foci 0.000121 0.000414 0.000417 0.000919 0.000332 0.000193 0.000613 0.000909 0.000227 0.000404 0.000506 0.000915
Nucleolus 0.000746 0.000885 0.000340 0.000389 0.001774 0.011284 0.000282 0.000701 0.001263 0.001359 0.000314 0.000515
Nucleus 0.102251 0.126105 0.248294 0.180400 0.275914 0.032069 0.341791 0.374848 0.189616 0.121816 0.291122 0.259120
Peroxisomes 0.010905 0.014646 0.000091 0.000825 0.003380 0.009564 0.000179 0.002352 0.007120 0.014414 0.000131 0.001443
Vacuole 0.067328 0.039935 0.036688 0.126152 0.028000 0.158781 0.051190 0.111871 0.047543 0.045356 0.043331 0.120370
Vacuole Periphery 0.001128 0.001790 0.000193 0.000503 0.000655 0.006232 0.000159 0.006720 0.000890 0.001993 0.000177 0.003020

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.77 1.90 1.24 4.04 -2.86 -1.76 -4.14 -3.26 -1.77 -1.53 -3.15 -0.61 -1.93 1.32 -1.77
Bud Neck 10.27 14.30 15.35 7.22 1.85 -3.17 1.36 -2.47 3.05 -4.00 4.02 13.51 13.39 6.05 -0.81
Bud Site -3.59 1.95 -1.06 2.45 -2.48 -2.98 -4.18 -4.96 2.44 0.42 -5.35 -1.38 -3.07 3.53 -1.92
Cell Periphery -3.70 11.75 5.57 4.67 -6.25 -0.31 5.22 -0.75 0.05 -7.26 -3.97 11.54 3.31 4.45 -9.34
Cytoplasm -0.01 -19.43 -13.04 -12.46 4.42 3.80 2.38 23.39 2.53 22.08 3.77 -12.50 3.47 -0.61 14.24
Cytoplasmic Foci 0.05 48.75 40.53 35.86 -17.64 -1.52 34.30 31.65 6.71 -5.80 -8.57 56.37 47.54 38.87 -18.18
Eisosomes 7.20 14.20 13.01 10.78 -14.55 -1.75 12.92 -1.95 1.55 -22.95 3.13 15.95 12.47 9.41 -25.16
Endoplasmic Reticulum -2.75 -9.89 -6.51 -1.45 1.05 4.31 -11.28 -18.44 -20.34 -11.54 -1.38 -14.19 -17.69 -12.18 -8.62
Endosome 1.71 16.83 8.61 6.76 -6.46 -4.48 9.25 0.32 4.50 -4.16 -4.61 18.73 6.76 9.05 -7.67
Golgi -3.61 10.61 9.58 8.02 -2.29 -2.31 2.69 0.75 2.32 -1.29 -6.03 10.86 9.14 8.11 -2.25
Lipid Particles -5.03 10.47 9.18 12.61 -5.61 0.03 10.12 8.30 1.16 -11.91 -6.34 14.46 12.33 12.55 -9.28
Mitochondria -0.14 6.98 7.05 7.95 3.09 -1.40 3.62 1.67 1.70 -1.40 -2.36 7.83 6.79 7.41 -1.17
Mitotic Spindle -1.03 -3.57 -2.09 -1.31 0.79 -1.96 -7.59 -4.62 0.80 2.26 -2.34 -7.66 -4.16 -1.60 2.04
None -3.17 -8.19 -1.65 1.60 2.65 5.42 3.51 3.61 -4.17 0.71 1.69 1.83 2.90 0.89 2.68
Nuclear Periphery -4.26 -25.22 -16.33 -3.04 11.83 5.52 -22.41 -23.03 -25.15 -7.79 -1.96 -32.32 -24.47 -13.02 0.80
Nuclear Periphery Foci -6.49 -10.43 -8.22 -4.86 -3.61 2.02 -7.30 -11.01 -11.56 -3.93 -3.73 -11.60 -11.82 -8.07 -4.83
Nucleolus -0.98 2.74 2.81 6.60 -0.07 -0.85 4.99 4.24 0.99 -3.35 0.05 5.68 5.17 1.98 -2.25
Nucleus -4.80 -32.80 -14.31 -8.84 14.84 25.58 -12.72 -15.39 -35.96 -5.21 11.63 -26.86 -15.44 -24.56 6.97
Peroxisomes -2.27 10.99 10.08 10.81 -3.43 -2.49 5.79 4.16 3.80 -1.94 -5.34 12.33 10.71 11.11 -3.75
Vacuole 8.20 2.64 -15.93 -21.30 -17.83 -5.36 -17.36 -25.99 -1.18 -16.82 -0.27 -10.63 -30.05 -27.80 -23.66
Vacuole Periphery -1.39 8.90 4.80 2.90 -2.28 -1.73 6.78 -1.59 1.23 -2.26 -2.30 11.15 -0.38 1.67 -2.67
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description mRNA 5'-end-capping quality-control protein; has distributive, 5'-3' exoRNase activity; similar to Rai1p;
Localization
Cell Percentages cytoplasm (36%), nucleus (7%), mixed (47%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Dxo1

Dxo1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Dxo1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available