Standard name
Description Xanthine-guanine phosphoribosyl transferase; required for xanthine utilization and for optimal utilization of guanine
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.06 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0.06 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0.06 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.98 0.97 1.0 0.97 0.85 0.82 0.79 – 0.63 0.69 0.66 0.61 0.98 0.99 0.98 0.95 0.95 0.95 0.93 0.86 0.94 0.94 0.87 0.81
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.1 0 – 0.14 0.14 0.21 0.2 0 0 0 0 0 0 0 0.05 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0.05 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0.05 0.19 0.12 0.18 – 0.22 0.22 0.16 0.21 0 0 0 0.06 0.07 0.06 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 1 0 0 – 0 0 0 0 0 0 0 0 0 0 1 0 0 0 4 4
Bud 0 1 1 1 0 2 0 – 0 1 1 5 0 0 0 0 0 0 4 0 1 2 10 9
Bud Neck 0 0 1 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 0 0 1 0 0 2 – 1 3 4 16 1 0 2 4 8 6 0 0 0 0 0 1
Cytoplasm 253 89 17 60 148 69 188 – 59 115 108 147 237 413 408 366 228 297 235 80 46 195 375 339
Endoplasmic Reticulum 0 0 0 0 1 0 8 – 3 3 1 0 0 1 0 8 6 5 1 1 0 0 2 6
Endosome 2 0 0 0 1 0 0 – 0 0 1 1 0 2 2 1 1 2 0 1 0 0 4 13
Golgi 0 0 0 0 1 0 0 – 0 0 0 0 0 0 0 2 1 0 1 0 0 0 3 3
Mitochondria 0 4 0 0 0 8 7 – 13 23 34 48 0 0 0 0 1 3 1 4 0 1 9 14
Nucleus 2 1 0 0 2 1 8 – 4 3 9 14 2 1 1 7 4 3 0 0 0 0 0 2
Nuclear Periphery 0 1 0 0 1 0 0 – 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 1 0 0 0 1 3 0 0 0 1 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 1 0 0 0 0 0 0 – 0 0 0 0 1 0 0 0 0 1 2 0 0 0 9 8
Vac/Vac Membrane 3 0 0 3 33 10 43 – 20 37 26 51 2 4 12 22 17 20 0 1 0 1 1 4
Unique Cell Count 259 92 17 62 174 84 239 93 167 164 242 241 419 416 386 241 314 252 93 49 207 431 418
Labelled Cell Count 262 96 20 65 188 90 256 100 186 184 282 244 421 425 410 267 340 252 93 49 207 431 418


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.6 5.1 6.3 7.1 10.5 6.8 9.8 – 8.2 8.2 7.7 8.4 7.2 6.8 6.5 10.9 11.3 11.1 6.1 6.2 6.3
Std Deviation (1e-4) 2.0 1.6 1.3 2.0 2.2 1.6 2.5 – 1.8 2.1 2.0 2.0 2.2 1.8 1.7 2.3 2.2 2.2 2.0 2.2 2.5
Intensity Change (Log2) – – – 0.18 0.74 0.13 0.65 – 0.39 0.4 0.3 0.42 0.2 0.13 0.05 0.8 0.85 0.83 -0.04 -0.01 0.01


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.8 -1.7 -1.9 -2.1 – -3.0 -2.7 -2.9 -3.2 -0.5 -0.5 -0.6 -1.0 -1.0 -1.0
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0