| Standard name | |
|---|---|
| Description | Zn(II)2Cys6 family transcription factor; positively regulates sterol uptake genes under anaerobic conditions; involved in hypoxic gene expression; represses filamentation-inducing genes during vegetative growth; positively regulates mating with SUT2 by repressing expression of genes that act as mating inhibitors; repressed by STE12; relocalizes from the nucleus to the cytoplasm upon DNA replication stress; SUT1 has a paralog, SUT2, that arose from the whole genome duplication |
Micrographs
Sub-cellular Localization
Yeast GFP Assignment
Protein Abundance
Localization Change
External localization resources
| ensLOC | DeepLoc | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
| Cortical Patches | 0 | 0 | 0 | – | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 0 |
| Bud | 0 | 0 | 0 | – | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 2 | 0 | 0 | 0 | – | 0 | 1 | 4 | 5 | 0 | 4 | 8 | 6 |
| Bud Neck | 0 | 0 | 0 | – | 0 | 0 | 4 | 4 | 0 | 0 | 2 | 3 | 1 | 3 | 1 | – | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 5 |
| Bud Site | 0 | 0 | 0 | – | 0 | 0 | 0 | 2 | 3 | 2 | 3 | 8 | 0 | 0 | 0 | – | 0 | 0 | – | – | – | – | – | – |
| Cell Periphery | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cytoplasm | 17 | 20 | 1 | – | 14 | 22 | 51 | 63 | 54 | 64 | 24 | 69 | 23 | 99 | 244 | – | 56 | 30 | 7 | 13 | 0 | 11 | 22 | 29 |
| Endoplasmic Reticulum | 0 | 0 | 0 | – | 0 | 0 | 1 | 2 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | – | 7 | 11 | 0 | 0 | 0 | 2 | 2 | 1 |
| Endosome | 4 | 1 | 0 | – | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 13 | 4 | – | 24 | 18 | 4 | 6 | 0 | 2 | 2 | 8 |
| Golgi | 3 | 0 | 1 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 1 | 0 | 2 | 1 | 1 | 0 | 0 | 0 |
| Mitochondria | 22 | 133 | 1 | – | 0 | 3 | 16 | 28 | 107 | 91 | 83 | 128 | 3 | 2 | 1 | – | 21 | 8 | 4 | 11 | 0 | 3 | 7 | 9 |
| Nucleus | 202 | 246 | 29 | – | 5 | 4 | 8 | 27 | 31 | 50 | 42 | 59 | 132 | 99 | 20 | – | 77 | 59 | 198 | 255 | 46 | 176 | 135 | 108 |
| Nuclear Periphery | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| Nucleolus | 6 | 1 | 0 | – | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 1 | 0 | 0 | – | 1 | 1 | 20 | 25 | 3 | 20 | 16 | 20 |
| Peroxisomes | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| SpindlePole | 6 | 10 | 1 | – | 0 | 1 | 4 | 5 | 0 | 3 | 0 | 4 | 5 | 3 | 1 | – | 14 | 9 | 17 | 18 | 4 | 16 | 15 | 32 |
| Vac/Vac Membrane | 19 | 13 | 1 | – | 3 | 1 | 2 | 3 | 3 | 1 | 5 | 8 | 8 | 26 | 40 | – | 42 | 21 | 25 | 47 | 5 | 37 | 38 | 44 |
| Unique Cell Count | 251 | 340 | 33 | 22 | 30 | 79 | 117 | 156 | 165 | 119 | 214 | 163 | 239 | 295 | 197 | 131 | 292 | 394 | 67 | 288 | 257 | 279 | ||
| Labelled Cell Count | 279 | 424 | 34 | 22 | 31 | 87 | 136 | 201 | 214 | 161 | 285 | 173 | 245 | 312 | 244 | 159 | 292 | 394 | 67 | 288 | 257 | 279 | ||
Yeast GFP Assignment
Protein Abundance
| Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean Cell GFP Intensity (1e-4) | 5.0 | 4.0 | 5.6 | – | 4.9 | 4.1 | 3.9 | 4.3 | 3.2 | 3.4 | 3.3 | 3.4 | 5.4 | 5.1 | 4.6 | 4.5 | 5.5 | 5.6 | 5.8 | 5.8 | 5.6 |
| Std Deviation (1e-4) | 0.8 | 0.8 | 1.0 | – | 1.3 | 0.8 | 1.2 | 2.0 | 1.1 | 0.9 | 0.8 | 0.6 | 0.8 | 1.1 | 0.8 | 1.5 | 1.6 | 1.3 | 1.4 | 1.6 | 1.2 |
| Intensity Change (Log2) | – | – | – | – | -0.19 | -0.47 | -0.51 | -0.37 | -0.79 | -0.73 | -0.77 | -0.73 | -0.05 | -0.15 | -0.29 | -0.33 | -0.03 | -0.01 | 0.04 | 0.04 | -0.0 |
Localization Change
| Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – |
| Cyto | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – |
| Nuc | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – |
| SpindlePole | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – |
| Vac | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cortical Patches | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – |
| Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – |
| Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | – |
| Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | – | 2.5 | – |
External localization resources
