Standard name
Description Transcription factor; activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes; STP2 has a paralog, STP1, that arose from the whole genome duplication

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.05 0.07 0.19 0.85 0.74 0.65 0.53 0.6 0.53 0.5 0.43 0.55 0.2 0.42 0.72 0.32 0.24 0.28 0 0 0.16 0.4 0.63 0.4
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.05 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.1 0.16 0.12 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.29 0.1 0.47 0.2 0.27 0.51 0.66 0.55 0.64 0.68 0.73 0.63 0.05 0 0 0.13 0.05 0.07 0 0 0.07 0 0 0
Nucleus 0.77 0.73 0.27 0 0 0 0 0 0 0.05 0 0 0.68 0.25 0 0.3 0.47 0.53 0.66 0.69 0.32 0.2 0.08 0.11
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.13 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0.05 0.08 0.08 0.06 0.07
Vac/Vac Membrane 0.07 0.14 0.16 0 0.09 0 0 0 0 0 0 0 0.1 0.29 0.26 0.2 0.18 0.17 0.08 0.13 0.2 0.14 0.09 0.18
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 2 1
Bud 0 0 4 4 0 3 1 7 11 5 2 2 0 0 0 0 0 0 2 5 4 3 7 18
Bud Neck 0 0 2 0 1 0 0 2 1 2 1 0 0 0 0 0 1 0 0 1 3 2 7 8
Bud Site 0 1 0 0 0 1 4 1 2 1 0 2 1 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Cytoplasm 5 19 35 147 138 96 138 203 152 182 57 77 40 105 221 165 78 73 1 3 42 69 219 99
Endoplasmic Reticulum 0 0 2 0 0 1 0 0 0 2 1 0 0 1 0 39 17 13 0 0 1 0 2 4
Endosome 2 3 1 0 2 0 0 1 0 0 0 0 3 19 30 82 40 11 4 8 8 6 3 6
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 2 2 1 0 0 0
Mitochondria 32 28 84 34 51 75 172 188 185 246 96 89 10 10 4 69 15 17 2 6 19 4 12 7
Nucleus 86 196 48 1 1 3 6 12 8 17 5 5 135 64 9 155 155 136 82 220 83 35 26 28
Nuclear Periphery 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 2 0 1 0
Nucleolus 14 13 0 0 2 1 0 0 0 0 0 1 2 0 1 5 1 1 11 13 7 4 3 1
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 1 0 0 0
SpindlePole 1 0 2 1 1 0 1 5 5 0 0 0 0 0 1 27 12 1 4 15 20 14 19 18
Vac/Vac Membrane 8 37 28 4 16 5 8 11 10 5 1 3 20 74 79 103 58 43 9 40 51 24 29 46
Unique Cell Count 111 269 180 172 186 147 261 341 287 362 132 141 199 253 305 516 327 257 124 322 261 177 348 252
Labelled Cell Count 148 297 206 191 212 185 332 431 374 461 163 179 211 274 345 647 378 296 124 322 261 177 348 252


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.7 5.1 3.8 3.3 3.6 3.1 2.6 3.0 2.9 2.6 2.6 2.6 5.6 4.9 4.8 5.6 6.6 6.5 4.4 4.4 5.6
Std Deviation (1e-4) 0.7 1.0 0.6 1.0 1.3 1.1 1.0 0.8 0.9 0.6 0.5 0.8 1.2 1.0 1.5 1.5 1.5 1.6 1.2 1.1 1.9
Intensity Change (Log2) -0.19 -0.08 -0.3 -0.56 -0.36 -0.42 -0.57 -0.54 -0.57 0.55 0.37 0.33 0.55 0.79 0.78 0.22 0.2 0.54


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 12.4 10.5 8.4 7.1 8.7 7.2 6.9 4.5 6.6 0.2 4.8 11.3 3.2 1.1 2.1
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 3.2 2.3 2.2
Endosome 0 0 0 0 0 0 0 0 0 0 3.4 0 5.5 4.6 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 -9.4 -10.6 0 -9.3 -11.4 -9.8
Nucleus -7.1 -7.3 -6.1 -7.7 -7.9 -7.7 -7.4 -5.3 -5.5 8.0 -0.3 -7.8 0.9 4.6 5.5
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 2.4 0 0
Vacuole -4.3 -2.0 -3.6 -4.7 -5.1 -4.6 -6.5 -4.4 -4.0 -1.6 3.3 2.7 1.3 0.6 0.3


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Stp2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available