Standard name
Description Nuclear thiol peroxidase; functions as an alkyl-hydroperoxide reductase during post-diauxic growth

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0.05 0.05 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.05 0.07 0.08 0.12 0.08 0.09 0.06 0 0 0 0.05 0.1 0.15 0.2 0.13 0.11 0.09 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.1 0 0 0 0.16 0 0.13 0.06 0.18 0.15 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.84 0.81 0.88 0.83 0.85 0.81 0.88 0.85 0.85 0.82 0.81 0.89 0.82 0.76 0.84 0.83 0.83 0.83 0.8 0.82 0.68 0.65 0.65
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0.05 0 0.13 0.08 0.11 0.11 0 0 0 0 0 0 0 0 0 0 0 0.05
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.11 0.15 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.06 0 0.07 0.1 0.09 0.19 0.18 0.15
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 1 1 1
Bud 0 1 0 0 0 1 2 5 3 3 2 0 1 0 0 0 0 1 3 2 2 9 6
Bud Neck 0 0 0 0 0 0 0 1 0 2 2 0 0 0 0 0 0 0 0 0 0 1 0
Bud Site 0 0 0 0 0 12 1 17 9 20 21 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 11 12 19 37 26 29 29 15 18 9 23 17 43 60 19 14 13 4 3 5 3 4 9
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2 3 0 0 0 0 0 1 2
Endosome 0 3 0 5 1 0 1 0 3 0 0 0 1 2 0 1 0 5 0 0 1 1 4
Golgi 0 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 2 1 0 1 1
Mitochondria 9 17 2 12 2 51 16 55 31 66 69 3 0 1 3 3 6 2 0 1 2 5 3
Nucleus 181 134 203 262 294 263 443 353 407 306 371 158 240 229 121 105 116 196 135 206 106 210 206
Nuclear Periphery 1 0 1 5 15 4 8 8 14 3 3 0 0 1 0 0 0 0 0 0 0 0 1
Nucleolus 1 2 1 0 8 16 15 55 38 41 51 0 1 6 1 2 3 0 0 0 2 13 14
Peroxisomes 0 0 0 0 0 0 1 1 1 0 0 0 1 2 0 0 1 0 0 1 0 0 0
SpindlePole 1 0 4 8 5 1 3 1 5 1 8 0 0 4 0 0 1 2 2 4 2 9 11
Vac/Vac Membrane 23 24 7 10 13 10 11 2 12 6 2 3 9 14 5 8 6 17 16 21 29 56 48
Unique Cell Count 216 165 230 316 345 326 504 415 480 371 458 177 293 300 144 126 140 235 170 252 155 322 318
Labelled Cell Count 227 194 238 339 365 387 531 513 541 458 552 181 296 319 151 136 147 235 170 252 155 322 318


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.0 5.5 6.3 6.6 7.8 6.0 7.2 6.3 7.2 6.1 6.1 6.3 6.8 7.0 8.5 8.9 9.0 5.7 6.2 6.9
Std Deviation (1e-4) 0.9 1.5 1.9 2.0 2.2 2.2 1.9 1.7 2.2 1.9 1.7 1.7 2.0 2.0 2.9 2.5 2.8 2.0 1.9 2.8
Intensity Change (Log2) 0.05 0.3 -0.08 0.18 -0.0 0.18 -0.06 -0.05 -0.01 0.1 0.14 0.43 0.49 0.51 -0.16 -0.04 0.13


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 3.1 0 3.6 3.3 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.3 -0.3 0.3 -1.3 -2.5 -2.5 -3.3 -1.7 0.5 2.3 3.8 1.5 0.9 0.3
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 2.1 0 5.8 1.9 5.3 3.3 6.4 5.8 0 0 0 0 0 0
Nucleus -1.7 -1.0 -2.4 -0.1 -1.1 -1.2 -1.9 -2.4 0.3 -2.0 -3.5 -1.2 -1.3 -1.5
Nuclear Periphery 0 2.8 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 3.0 2.2 5.5 4.1 5.0 5.0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0.6 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0.1 0.5 0 -0.7 0 -0.4 0 0 0 0 0.9 0 1.5 0


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Dot5-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available