Standard name
Human Ortholog
Description Long chain fatty acyl-CoA synthetase; activates imported fatty acids with a preference for C16:0-C18:0 chain lengths; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.14 0.05 0 0 0.09 0 0.08 0.06 0.06 0 0 0.05 0.14 0.12 0.12 0.17 0.17 0.12 0.06 0.05 0.06 0.06 0.08 0.05
Bud 0.06 0.05 0 0 0 0 0 0 0.05 0.05 0.07 0.05 0.09 0 0 0 0 0 0 0.05 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.06 0.06 0 0.05
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.46 0.39 0.36 0.34 0.32 0.2 0.15 0.08 0.14 0.11 0.09 0.1 0.59 0.51 0.49 0.63 0.61 0.69 0.52 0.35 0.42 0.52 0.63 0.59
Cytoplasm 0.61 0.75 0.79 0.8 0.71 0.81 0.8 0.81 0.77 0.78 0.74 0.74 0.58 0.65 0.66 0.32 0.29 0.27 0.19 0.28 0.25 0.16 0.07 0.13
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.07 0.09 0.07 0 0.05 0 0.06
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.09 0.1 0.07 0.19 0.17 0.22 0.19 0 0 0 0.07 0 0 0 0 0.07 0.05 0.06 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 32 12 16 15 41 22 48 32 34 22 19 23 29 41 50 71 44 34 15 14 24 11 21 20
Bud 15 11 2 6 13 15 26 22 27 23 35 27 18 10 15 8 11 10 3 14 16 8 11 15
Bud Neck 0 2 13 9 18 10 20 16 11 13 4 8 0 1 0 0 1 0 9 24 24 12 12 18
Bud Site 1 0 0 0 2 1 1 0 2 1 0 1 0 1 0 0 0 0 – – – – – –
Cell Periphery 107 86 135 124 141 99 92 40 74 54 45 51 124 180 214 268 161 190 129 93 176 103 181 229
Cytoplasm 141 165 298 290 316 405 482 426 406 382 360 369 122 229 286 135 78 75 46 73 105 32 19 51
Endoplasmic Reticulum 4 6 6 1 3 7 5 8 4 4 0 4 1 1 4 20 3 19 23 18 10 10 12 22
Endosome 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2 0 0 0 2 2 3 0 0 1
Golgi 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 2 3 2 1 0 2 2 1 0
Mitochondria 3 1 1 11 9 44 63 37 99 83 108 95 0 1 0 28 9 10 9 9 30 9 16 14
Nucleus 2 1 0 0 0 0 0 4 1 1 7 1 0 1 1 3 3 5 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 3 2 0 1 2 0 0 0 1 0 0 0 0 0 1 0 0 0
Nucleolus 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0
SpindlePole 3 0 3 2 7 6 5 9 4 12 2 12 0 1 3 8 3 10 0 0 2 1 1 2
Vac/Vac Membrane 0 1 1 0 0 2 4 11 2 8 13 10 1 0 0 8 6 1 4 7 15 4 6 8
Unique Cell Count 232 219 376 363 442 497 604 529 524 491 488 499 209 352 434 428 266 277 251 264 424 201 288 387
Labelled Cell Count 308 285 476 458 552 611 749 607 664 605 596 601 295 467 577 551 322 356 251 264 424 201 288 387


Cell Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.9 6.4 6.1 5.7 6.1 4.8 4.9 5.2 4.3 4.5 4.3 4.8 7.0 7.0 7.2 10.8 10.6 10.7 6.2 7.0 6.8
Std Deviation (1e-4) 2.4 2.2 1.5 1.7 1.5 1.3 1.3 1.3 1.2 1.4 1.4 1.3 2.1 2.3 2.3 2.2 2.2 2.1 2.1 2.3 2.1
Intensity Change (Log2) – – – -0.1 0.01 -0.35 -0.31 -0.24 -0.52 -0.46 -0.5 -0.35 0.19 0.2 0.24 0.82 0.8 0.81 0.01 0.19 0.15


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.1 2.8 0 2.3 1.2 0 0 0 0 4.2 3.7 3.8 5.6 5.3 3.8
Bud 0 2.6 0 3.4 3.3 0 0 0 0 5.2 2.4 2.9 0 3.2 2.9
Bud Neck -0.8 0.5 0 -0.1 -0.4 0 0 0 0 0 -3.1 -3.9 -3.9 -2.6 -3.1
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -0.5 -1.2 0 -7.5 -10.6 0 0 0 0 5.5 4.1 3.8 7.6 6.2 8.3
Cytoplasm 0.2 -2.6 0.8 0.2 0.5 -0.6 -0.5 -1.9 -1.8 -5.4 -4.3 -4.2 -13.5 -12.7 -13.3
Endoplasmic Reticulum 0 0 0 0 -0.1 0 0 0 0 0 0 0 2.5 0 3.5
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 3.0 0 0 6.3 5.0 0 0 0 0 0 0 0 4.8 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 1.3 0 2.5
Vacuole 0 0 0 0 0 0 0 2.8 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.9378 1.8938 1.0914 1.795 0.8741 1.2894 1.1638 2.019 1.2883 1.3462 -0.1744 0.9986 0.9492 1.2072 0.3882 1.3135 0.9868 1.195
Actin 0.0672 0.0142 0.0084 0.0589 0.0934 0.0182 0.0332 0.0059 0.0217 0.0292 0.0177 0.0257 0.0557 0.0292 0.0212 0.0039 0.0124 0.0043
Bud 0.0012 0.0022 0.0015 0.0026 0.0094 0.003 0.0021 0.0014 0.0029 0.0009 0.0046 0.0011 0.0015 0.0005 0.0014 0.0018 0.0014 0.0005
Bud Neck 0.0086 0.0067 0.0272 0.0318 0.0138 0.0366 0.0055 0.0089 0.0395 0.0107 0.0678 0.0499 0.005 0.0057 0.0223 0.0205 0.04 0.0681
Bud Periphery 0.0083 0.0076 0.0141 0.0443 0.0421 0.0313 0.014 0.0038 0.0125 0.0069 0.0309 0.0128 0.0037 0.0016 0.0116 0.0166 0.0065 0.0063
Bud Site 0.0318 0.1714 0.0731 0.0132 0.0129 0.0043 0.0275 0.1809 0.0711 0.0059 0.0211 0.0037 0.0255 0.105 0.0401 0.0037 0.0303 0.0067
Cell Periphery 0.3241 0.2427 0.2602 0.4082 0.3326 0.3304 0.3763 0.3848 0.3435 0.3546 0.3098 0.3267 0.2392 0.1815 0.1897 0.3061 0.1096 0.2588
Cytoplasm 0.3222 0.4093 0.3505 0.3451 0.3168 0.4063 0.2895 0.3038 0.3202 0.2626 0.3492 0.3551 0.3373 0.4677 0.3955 0.5025 0.4901 0.4269
Cytoplasmic Foci 0.0151 0.0034 0.0141 0.0006 0.007 0.003 0.0139 0.0034 0.0095 0.0072 0.0069 0.0118 0.0189 0.0024 0.0053 0.0293 0.0226 0.0015
Eisosomes 0.0085 0.0035 0.0047 0.0034 0.0023 0.0024 0.0038 0.0019 0.0033 0.0015 0.0005 0.0009 0.0013 0.001 0.0007 0.001 0.0028 0.0017
Endoplasmic Reticulum 0.0097 0.0031 0.0042 0.0037 0.009 0.0067 0.0053 0.0027 0.0032 0.0056 0.0036 0.003 0.0117 0.0118 0.0081 0.0121 0.002 0.0039
Endosome 0.0101 0.0005 0.0066 0.0017 0.0184 0.0042 0.0185 0.0023 0.0055 0.0308 0.0318 0.0066 0.004 0.0003 0.0023 0.0011 0.0004 0.0002
Golgi 0.006 0.0012 0.0036 0.0053 0.015 0.0011 0.0138 0.001 0.0045 0.0297 0.0131 0.0063 0.0042 0.0007 0.0085 0.0007 0.0005 0.0003
Lipid Particles 0.0062 0.0007 0.0054 0.0011 0.0067 0.0013 0.0163 0.0006 0.0025 0.0077 0.002 0.0061 0.0124 0.0015 0.0037 0.0041 0.0023 0.0004
Mitochondria 0.003 0.0002 0.0045 0.0007 0.0154 0.0013 0.0114 0.0005 0.006 0.0581 0.0063 0.002 0.0008 0.0001 0.006 0.0005 0.0004 0.0001
None 0.1596 0.1293 0.2046 0.0742 0.0772 0.1378 0.1552 0.0946 0.1389 0.1775 0.1266 0.1815 0.2644 0.1882 0.2709 0.0809 0.2724 0.218
Nuclear Periphery 0.0025 0.0003 0.0005 0.0013 0.0071 0.0047 0.0013 0.0003 0.0004 0.0004 0.0006 0.0002 0.0009 0.0004 0.0009 0.0007 0.0002 0.0002
Nucleolus 0.0007 0.0003 0.0026 0.0002 0.0008 0.0003 0.0005 0.0002 0.0005 0.0002 0.0002 0.0002 0.0007 0.0001 0.0001 0.0006 0.0011 0.0001
Nucleus 0.0017 0.0006 0.0015 0.0005 0.0029 0.0011 0.0008 0.0005 0.0009 0.0004 0.0007 0.0004 0.0005 0.0004 0.0005 0.0009 0.0007 0.0003
Peroxisomes 0.0044 0.0002 0.0075 0.0001 0.0041 0.0007 0.0055 0.0001 0.0052 0.0049 0.0004 0.0033 0.0081 0.0004 0.0065 0.0009 0.0002 0
Punctate Nuclear 0.0049 0.0003 0.0016 0.0002 0.0032 0.0004 0.001 0.0002 0.0017 0.0002 0.0003 0.0003 0.0016 0.0002 0.0002 0.0041 0.0008 0.0001
Vacuole 0.0038 0.0022 0.0033 0.0025 0.0087 0.0045 0.0039 0.002 0.006 0.0037 0.0052 0.0021 0.0024 0.0012 0.0042 0.0078 0.0031 0.0014
Vacuole Periphery 0.0005 0 0.0002 0.0003 0.0014 0.0005 0.0008 0.0001 0.0005 0.0015 0.0009 0.0002 0.0001 0 0.0002 0.0002 0.0001 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 19.8454 15.1386 35.1047 66.1825 47.0009 14.8097 19.6116 20.1777 48.8711 53.5981
Translational Efficiency 0.3471 0.5648 0.4836 0.6118 0.6707 0.5439 0.5444 0.5001 0.4686 0.5578

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
264 90 1110 928 1235 98 206 125 1499 188 1316 1053

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 615.41 766.16 1384.84 1025.93 772.36 774.65 1173.68 921.54 744.72 770.59 1351.79 1013.54
Standard Deviation 91.68 149.13 354.01 188.58 157.62 142.34 233.33 160.82 159.76 145.69 346.57 188.55
Intensity Change Log 2 — 0.316098 1.170100 0.737313 — 0.004271 0.603694 0.254773 — 0.150920 0.882541 0.488833

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002134 0.006363 0.019975 0.046193 0.006821 0.005406 0.037066 0.019101 0.005996 0.005864 0.022650 0.042977
Bud Neck 0.053953 0.065382 0.021813 0.030752 0.057591 0.040079 0.018181 0.024644 0.056950 0.052192 0.021244 0.030027
Bud Site 0.025726 0.039645 0.134559* 0.164581* 0.114356* 0.042476 0.084620 0.105133* 0.098747 0.041121 0.126742* 0.157524*
Cell Periphery 0.019610 0.004227 0.512714* 0.088176 0.117254* 0.002951 0.118459* 0.040557 0.100057* 0.003562 0.450999* 0.082523
Cytoplasm 0.504750* 0.231624* 0.145418* 0.355346* 0.459919* 0.272335* 0.220699* 0.346570* 0.467815* 0.252846* 0.157203* 0.354304*
Cytoplasmic Foci 0.140410 0.262106* 0.004291 0.022836 0.075989 0.241756* 0.051947 0.083126 0.087334 0.251498* 0.011751 0.029993
Eisosomes 0.010104 0.003902 0.005471 0.011476 0.012284 0.004932 0.007932 0.006486 0.011900 0.004439 0.005856 0.010884
Endoplasmic Reticulum 0.003994 0.001930 0.033077 0.007867 0.004992 0.005802 0.017404 0.015469 0.004817 0.003948 0.030623 0.008769
Endosome 0.007463 0.039092 0.001697 0.004767 0.003669 0.019592 0.005283 0.004550 0.004337 0.028927 0.002258 0.004741
Golgi 0.003740 0.025375 0.001439 0.002703 0.002726 0.015020 0.001035 0.000918 0.002905 0.019977 0.001376 0.002491
Lipid Particles 0.011150 0.007971 0.018383 0.006387 0.003405 0.010257 0.018376 0.008778 0.004769 0.009163 0.018381 0.006671
Mitochondria 0.006908 0.007109 0.000786 0.000828 0.003071 0.011292 0.000063 0.000072 0.003747 0.009290 0.000673 0.000738
Mitotic Spindle 0.000938 0.006139 0.000723 0.005032 0.000096 0.042370 0.000181 0.000073 0.000244 0.025025 0.000638 0.004443
None 0.001143 0.000557 0.000313 0.000334 0.001342 0.002289 0.001967 0.000392 0.001307 0.001460 0.000572 0.000341
Nuclear Periphery 0.001043 0.000380 0.000821 0.000151 0.000097 0.000709 0.000269 0.000303 0.000264 0.000552 0.000735 0.000169
Nuclear Periphery Foci 0.001072 0.001151 0.002267 0.002499 0.000634 0.001594 0.005603 0.005152 0.000711 0.001382 0.002790 0.002814
Nucleolus 0.000833 0.003681 0.000079 0.000063 0.000185 0.006620 0.000098 0.000113 0.000299 0.005213 0.000082 0.000069
Nucleus 0.146407* 0.082346 0.025927 0.030051 0.057888 0.113550 0.052233 0.088373 0.073477 0.098612 0.030045 0.036975
Peroxisomes 0.014453 0.077800 0.000965 0.001294 0.002935 0.029902 0.001470 0.001096 0.004964 0.052832 0.001044 0.001270
Vacuole 0.043305 0.131515 0.068647 0.217960* 0.074322 0.128649 0.357023* 0.248994* 0.068860 0.130021 0.113788 0.221644*
Vacuole Periphery 0.000863 0.001705 0.000637 0.000702 0.000422 0.002419 0.000092 0.000102 0.000499 0.002077 0.000551 0.000631

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.45 -11.51 -14.37 -9.36 -6.83 0.61 -3.18 -2.30 -2.27 1.44 0.24 -9.25 -13.17 -10.57 -5.75
Bud Neck -0.64 4.27 3.51 2.95 -2.64 1.68 12.20 5.75 1.17 -1.34 0.84 11.91 9.34 2.64 -3.12
Bud Site -1.18 -13.64 -14.78 -9.71 -1.20 5.40 3.99 1.38 -2.55 -1.25 6.45 -3.72 -5.50 -10.30 -1.80
Cell Periphery 3.15 -42.52* -7.98 -13.49 37.26* 16.22 2.08 7.71 -3.82 2.98 16.41 -29.41 4.04 -14.20 33.62*
Cytoplasm 9.37 22.57 9.57 -4.22 -19.65 7.77 15.84 5.70 -2.43 -5.83 11.80 36.67 12.56 -5.04 -20.27
Cytoplasmic Foci -4.73 15.26 12.91 9.99 -10.96 -6.25 5.42 -0.03 5.67 -2.64 -9.03 21.48 14.45 12.62 -8.50
Eisosomes 2.25 1.84 0.07 -3.90 -4.69 2.25 4.53 3.83 -0.33 0.14 3.75 6.11 1.98 -2.67 -4.52
Endoplasmic Reticulum 1.51 -11.79 -2.43 -5.90 11.35 -0.35 -4.16 -1.86 -1.51 0.17 0.50 -12.44 -2.83 -2.65 10.88
Endosome -4.53 4.75 2.07 5.02 -2.82 -5.28 -2.94 -1.24 5.00 1.23 -6.60 6.34 -0.01 6.46 -2.53
Golgi -2.20 3.15 1.46 2.35 -1.28 -1.72 8.74 7.85 2.03 -0.18 -2.85 7.27 1.25 2.98 -1.33
Lipid Particles 1.57 -3.15 3.53 1.29 6.96 -1.82 -4.46 -2.90 0.54 2.29 -2.07 -8.43 -2.33 1.40 7.39
Mitochondria 0.03 2.00 2.02 2.34 0.27 -1.36 3.67 3.63 1.94 -1.65 -1.57 3.51 3.43 2.64 0.14
Mitotic Spindle -1.11 0.09 -2.55 0.20 -2.73 -2.91 -2.06 -1.60 2.90 -0.07 -3.05 -2.88 -3.17 2.67 -2.75
None 1.90 3.69 3.54 1.04 -0.23 -0.82 -0.13 2.65 1.70 0.91 -0.20 2.64 3.72 1.97 0.69
Nuclear Periphery 0.89 0.29 1.17 1.61 14.10 -3.27 -6.67 -3.58 0.40 -1.11 -1.81 -3.88 0.10 2.70 12.03
Nuclear Periphery Foci -0.34 -1.54 -1.73 -2.05 -0.79 -1.46 -8.03 -3.97 -0.67 0.28 -1.69 -10.07 -8.33 -0.35 -0.03
Nucleolus -1.23 2.69 2.77 1.49 1.21 -1.56 3.10 1.94 1.57 -1.00 -2.06 3.99 4.33 2.15 0.97
Nucleus 3.60 9.85 9.65 3.36 -1.12 -2.91 -0.67 -3.10 0.25 -2.41 -2.12 7.46 5.94 4.36 -1.90
Peroxisomes -3.51 3.26 3.20 4.40 -1.01 -2.92 5.21 7.48 3.15 0.57 -4.85 5.15 4.98 5.27 -0.87
Vacuole -4.57 -6.24 -23.52 -5.77 -21.18 -3.01 -16.57 -8.94 -4.02 5.96 -4.57 -9.73 -22.99 -7.18 -13.41
Vacuole Periphery -1.29 1.08 0.82 1.70 0.08 -2.19 6.13 5.94 2.58 -0.70 -2.84 -0.72 -0.26 2.57 -0.03
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Long chain fatty acyl-CoA synthetase; activates imported fatty acids with a preference for C16:0-C18:0 chain lengths; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
Localization
Cell Percentages cell periphery (22%), cytoplasm (19%), mixed (28%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Faa3

Faa3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Faa3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available