Standard name
Human Ortholog
Description Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p; associates with actin patches on cell cortex; promotes protein-protein interactions essential for endocytosis; binds to and activates Arp2/3 complex in vitro; phosphorylation of Thr-1225 is regulated by MAPK Hog1p in response to osmotic stress; previously thought to be a subunit of poly(A) ribonuclease
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.5 0.55 0.72 0.74 0.62 0.57 0.46 0.44 0.43 0.46 0.52 0.46 0.69 0.65 0.58 0.49 0.59 0.35 0.84 0.83 0.91 0.78 0.76 0.82
Bud 0.14 0.16 0.14 0.21 0.23 0.19 0.16 0.18 0.19 0.17 0.17 0.17 0.18 0.13 0.08 0.15 0.18 0 0 0.06 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0.05 0 – – – – – –
Cell Periphery 0.14 0.14 0.13 0.09 0.07 0.07 0.05 0.06 0.07 0.06 0.11 0.06 0.22 0.21 0.36 0.07 0.08 0.06 0 0 0 0 0 0
Cytoplasm 0.09 0.13 0.06 0.05 0.07 0 0.05 0 0 0 0 0 0 0.08 0.09 0.22 0.13 0.24 0 0 0 0 0 0
Endoplasmic Reticulum 0.15 0.16 0.07 0.07 0.09 0.15 0.11 0.06 0 0.07 0.07 0.05 0.17 0.24 0.24 0 0.05 0.12 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.12 0 0 0 0 0 0
Golgi 0.34 0.1 0.28 0.27 0.24 0.11 0.18 0.2 0.13 0.09 0.16 0.06 0.38 0.34 0.44 0.33 0.41 0.41 0 0 0 0.05 0.05 0.07
Mitochondria 0.06 0.17 0.1 0.31 0.19 0.54 0.51 0.57 0.73 0.72 0.77 0.76 0 0 0 0.07 0.11 0.06 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0
Peroxisomes 0 0 0.14 0.09 0.11 0.07 0.09 0.08 0.13 0.09 0.08 0.15 0 0 0 0.13 0.1 0.24 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 133 100 188 131 140 165 143 185 117 159 202 178 88 74 71 33 36 6 307 192 293 157 132 145
Bud 36 29 36 37 53 55 51 74 52 57 68 66 23 15 10 10 11 0 15 14 7 4 2 1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 3 1 1 0 0
Bud Site 2 2 8 2 7 7 5 14 5 12 8 20 1 0 0 2 3 0 – – – – – –
Cell Periphery 38 25 34 16 16 19 17 25 20 20 43 22 28 24 44 5 5 1 4 1 1 0 0 1
Cytoplasm 25 24 16 9 16 10 16 9 6 5 6 2 4 9 11 15 8 4 6 3 1 3 2 1
Endoplasmic Reticulum 40 30 19 13 21 45 34 25 9 25 26 18 21 27 30 1 3 2 6 4 1 7 3 2
Endosome 2 1 7 1 2 1 4 4 0 0 1 4 1 0 0 0 1 2 3 1 2 3 5 5
Golgi 90 19 73 47 54 32 57 83 34 32 61 23 48 38 54 22 25 7 6 3 5 10 9 11
Mitochondria 16 31 27 54 42 157 157 237 196 247 302 299 5 2 0 5 7 1 3 3 0 3 2 2
Nucleus 0 0 0 0 0 1 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 3 0 3 0 2 0 0 0 1 0 0 0 1 0 0 1 1
Nucleolus 3 1 5 0 4 6 5 12 8 10 9 3 0 0 0 2 0 1 0 0 0 0 0 0
Peroxisomes 0 0 37 15 25 21 29 34 35 30 31 57 3 5 5 9 6 4 0 0 4 2 7 4
SpindlePole 0 2 4 1 7 1 4 3 3 5 2 4 1 0 0 2 3 0 0 0 0 0 0 0
Vac/Vac Membrane 7 2 5 3 6 1 6 9 2 5 3 1 0 0 0 0 2 0 1 0 0 1 2 0
Unique Cell Count 266 182 260 176 226 291 310 418 269 345 391 391 127 113 123 67 61 17 368 232 322 201 174 177
Labelled Cell Count 392 266 459 329 393 521 528 717 487 610 764 700 223 194 225 107 110 28 368 232 322 201 174 177


Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 23.6 24.0 18.2 17.5 16.8 15.5 15.1 14.7 13.3 13.0 13.1 12.4 21.3 21.7 22.0 13.5 15.9 20.6 21.3 22.7 25.0
Std Deviation (1e-4) 6.4 7.5 4.3 3.8 4.2 4.1 3.8 3.7 3.4 3.5 3.2 3.0 5.0 5.6 6.1 3.7 6.3 7.7 4.9 6.0 5.7
Intensity Change (Log2) – – – -0.06 -0.11 -0.23 -0.27 -0.3 -0.45 -0.49 -0.47 -0.55 0.23 0.26 0.28 -0.42 -0.19 0.18 0.23 0.32 0.46


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0.5 -2.4 -3.8 -6.3 -7.1 -6.7 -6.5 -5.3 -6.7 -0.6 -1.3 -2.8 -3.6 -2.0 -3.2
Bud 2.0 2.7 1.6 0.9 1.3 1.7 0.9 1.2 1.0 1.1 -0.1 -1.6 0.2 0.8 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 -0.5 -1.2 0.2 -0.9 0.3 -0.8 1.3 0 0 0 0 0 0
Cell Periphery -1.3 -2.2 -2.6 -3.2 -3.2 -2.1 -3.1 -0.8 -3.3 2.3 2.0 5.1 -1.3 -1.0 0
Cytoplasm -0.5 0.4 -1.5 -0.5 -2.7 -2.3 -3.1 -3.2 -4.3 -1.3 0.6 1.0 4.0 0 0
Endoplasmic Reticulum 0 0.8 3.0 1.5 -0.7 -2.0 0 -0.3 -1.5 2.8 4.5 4.7 0 0 0
Endosome 0 0 0 -1.2 0 0 0 0 0 0 0 0 0 0 0
Golgi -0.3 -1.0 -5.1 -2.7 -2.5 -4.4 -6.0 -3.9 -7.8 1.9 1.1 3.1 0.8 2.0 0
Mitochondria 5.3 2.6 10.8 10.2 12.0 14.5 15.0 16.7 16.5 -2.2 -2.9 -3.7 -0.7 0.2 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0.1 0 0.8 0.8 0.8 0.3 0 0 0 0 0 0 0
Peroxisomes -1.8 -1.0 -2.7 -1.8 -2.5 -0.4 -2.1 -2.6 0.1 -3.6 -2.8 -3.0 -0.2 -0.9 0
SpindlePole 0 1.2 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0.5 0 0 0.2 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 19.5369 19.6246 20.2444 18.7235 17.1536 21.0752 17.0537 21.2592 19.4368 17.3211 17.2263 19.8027 18.825 21.9064 19.1971 20.0677 20.0284 20.1804
Actin 0.8473 0.8881 0.9386 0.8564 0.824 0.9037 0.827 0.8365 0.9231 0.9775 0.9011 0.9739 0.7202 0.8596 0.9221 0.8875 0.9532 0.9721
Bud 0.0011 0.0013 0.0028 0.0161 0.0032 0.0004 0.001 0.0028 0.0027 0.0014 0.0027 0.0003 0.0008 0.0126 0.0093 0.0059 0.0032 0.0005
Bud Neck 0.0055 0.0023 0.0072 0.001 0.0015 0.0212 0.0121 0.0022 0.0028 0.0003 0.0035 0.0129 0.0037 0.0008 0.0014 0.0103 0.0166 0.0186
Bud Periphery 0.0016 0.0012 0.0043 0.0383 0.0059 0.0007 0.0018 0.0046 0.0033 0.0029 0.0046 0.0004 0.0007 0.0066 0.0108 0.0126 0.0059 0.0006
Bud Site 0.0103 0.0716 0.01 0.0019 0.0044 0.0009 0.0241 0.0895 0.0094 0.0008 0.0031 0.0004 0.0052 0.0505 0.011 0.0085 0.0061 0.0005
Cell Periphery 0.0015 0.0012 0.0007 0.0009 0.0011 0.0007 0.0012 0.0006 0.0007 0.0001 0.0002 0.0002 0.0009 0.0001 0.0004 0.0022 0.0037 0.0003
Cytoplasm 0.0029 0.0068 0.0022 0.0121 0.0139 0.0007 0.0067 0.0018 0.0047 0.0001 0.0002 0.0001 0.0049 0.0084 0.0031 0.0012 0.0056 0.0002
Cytoplasmic Foci 0.0099 0.0034 0.0031 0.0145 0.0239 0.0004 0.0158 0.0145 0.0097 0.0011 0.0037 0.0003 0.0825 0.036 0.0009 0.0003 0.001 0.0002
Eisosomes 0.0756 0.0029 0.0071 0.0037 0.0052 0.0582 0.0337 0.0287 0.0021 0.0009 0.0065 0.0035 0.1213 0.001 0.0006 0.0689 0.0013 0.0045
Endoplasmic Reticulum 0.0017 0.0004 0.0006 0.0002 0.0006 0.0001 0.0018 0.0002 0.0009 0.0001 0.0001 0 0.0007 0.0001 0.0016 0.0001 0.0003 0
Endosome 0.0095 0.0013 0.0029 0.0019 0.01 0.0003 0.0073 0.0005 0.0098 0.0006 0.0005 0.0004 0.0115 0.0015 0.0186 0.0003 0.0002 0.0001
Golgi 0.0115 0.0149 0.0043 0.0316 0.0277 0.0097 0.0083 0.0131 0.0102 0.0053 0.0033 0.0073 0.029 0.0052 0.0031 0.0013 0.0015 0.0022
Lipid Particles 0.0056 0.0007 0.0021 0.0076 0.008 0.0002 0.0039 0.0007 0.0054 0.0029 0.0041 0.0001 0.002 0.0005 0.0004 0.0002 0.0004 0
Mitochondria 0.0059 0.0015 0.0052 0.0037 0.0506 0.0025 0.0019 0.0004 0.0079 0.0044 0.0577 0.0001 0.0026 0.0005 0.0017 0.0001 0.0001 0.0001
None 0.0011 0.0002 0.0016 0.0009 0.0005 0 0.023 0.0006 0.0014 0.0001 0.0017 0 0.0012 0.0001 0.0003 0 0 0
Nuclear Periphery 0.0026 0.0001 0.0013 0.0002 0.0001 0 0.0031 0 0.0002 0.0001 0.0001 0 0.0002 0 0.0062 0.0001 0.0001 0
Nucleolus 0.0002 0.0007 0.0003 0.0005 0.0005 0 0.0027 0 0 0 0.0001 0 0 0 0.0001 0 0 0
Nucleus 0.0006 0.0001 0.0009 0.0002 0.0002 0 0.0068 0 0 0 0 0 0.0001 0 0.001 0.0001 0.0001 0
Peroxisomes 0.002 0.0009 0.0009 0.0033 0.007 0.0002 0.0036 0.0031 0.0051 0.0014 0.0063 0.0001 0.0108 0.0162 0.0003 0.0001 0.0004 0.0001
Punctate Nuclear 0.0017 0.0001 0.0032 0.0045 0.0002 0 0.0129 0.0002 0.0003 0 0.0002 0 0.0014 0.0003 0.0001 0 0.0001 0
Vacuole 0.0015 0.0003 0.0003 0.0004 0.0087 0 0.001 0 0.0002 0 0.0001 0 0.0001 0.0001 0.004 0.0003 0.0002 0
Vacuole Periphery 0.0005 0.0001 0.0002 0.0002 0.003 0 0.0003 0 0.0001 0.0001 0.0003 0 0.0001 0 0.0029 0 0 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 101.698 75.9263 69.5197 86.9378 81.9471 94.8159 81.7635 85.8263 86.0425 97.7444
Translational Efficiency 1.5064 1.3831 1.2745 1.1025 1.2669 1.6331 1.0554 1.0482 1.1905 1.1582

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1510 1153 833 627 1861 1539 925 1553 3371 2692 1758 2180

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1517.00 1645.40 2050.55 1908.69 1257.68 1670.54 1822.94 1965.83 1373.84 1659.77 1930.79 1949.40
Standard Deviation 269.44 308.34 364.80 361.83 397.26 299.00 302.07 375.77 369.15 303.29 352.11 372.71
Intensity Change Log 2 — 0.117217 0.434790 0.331362 — 0.409550 0.535502 0.644374 — 0.257097 0.481313 0.481696

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.719173* 0.767258* 0.593422* 0.607435* 0.877164* 0.736694* 0.685911* 0.685354* 0.806394* 0.749785* 0.642086* 0.662943*
Bud Neck 0.026888 0.011744 0.036404 0.015909 0.006769 0.021518 0.038422 0.020000 0.015781 0.017332 0.037466 0.018823
Bud Site 0.144437* 0.007493 0.063227 0.017004 0.015538 0.022770 0.043258 0.019490 0.073277 0.016227 0.052720 0.018775
Cell Periphery 0.028001 0.008866 0.019580 0.017024 0.009343 0.019626 0.031593 0.025693 0.017701 0.015018 0.025901 0.023199
Cytoplasm 0.003039 0.000190 0.001911 0.000138 0.000658 0.000810 0.000424 0.000173 0.001724 0.000545 0.001129 0.000163
Cytoplasmic Foci 0.001581 0.000675 0.004891 0.000472 0.001040 0.002216 0.000168 0.000211 0.001282 0.001556 0.002406 0.000286
Eisosomes 0.049550 0.140051* 0.145828* 0.310802* 0.067492 0.171577* 0.162684* 0.230904* 0.059455 0.158074* 0.154697* 0.253884*
Endoplasmic Reticulum 0.005227 0.018562 0.048916 0.010376 0.004485 0.007803 0.014806 0.007119 0.004818 0.012411 0.030969 0.008056
Endosome 0.006466 0.009444 0.019760 0.003078 0.003113 0.005344 0.005500 0.002718 0.004615 0.007100 0.012257 0.002821
Golgi 0.004287 0.018914 0.022062 0.004796 0.003297 0.004210 0.005004 0.001791 0.003741 0.010508 0.013087 0.002656
Lipid Particles 0.002857 0.013330 0.036824 0.002515 0.003394 0.003667 0.007575 0.003043 0.003153 0.007806 0.021434 0.002891
Mitochondria 0.003944 0.001351 0.000679 0.007271 0.002326 0.001465 0.002136 0.002329 0.003051 0.001417 0.001446 0.003751
Mitotic Spindle 0.000704 0.000050 0.000581 0.000153 0.000124 0.000201 0.000094 0.000080 0.000384 0.000136 0.000325 0.000101
None 0.000054 0.000114 0.000057 0.000147 0.001017 0.000072 0.000077 0.000092 0.000586 0.000090 0.000068 0.000108
Nuclear Periphery 0.000044 0.000051 0.000165 0.000109 0.000023 0.000037 0.000094 0.000072 0.000032 0.000043 0.000128 0.000082
Nuclear Periphery Foci 0.000119 0.000027 0.000282 0.000034 0.000120 0.000032 0.000077 0.000019 0.000120 0.000030 0.000174 0.000023
Nucleolus 0.000038 0.000003 0.000004 0.000022 0.000062 0.000004 0.000007 0.000007 0.000051 0.000004 0.000005 0.000011
Nucleus 0.000187 0.000057 0.000136 0.000088 0.001226 0.000061 0.000103 0.000060 0.000761 0.000059 0.000118 0.000068
Peroxisomes 0.000862 0.001443 0.001088 0.000492 0.002448 0.001047 0.000290 0.000418 0.001738 0.001217 0.000668 0.000439
Vacuole 0.001603 0.000222 0.003836 0.001149 0.000291 0.000479 0.001500 0.000323 0.000879 0.000369 0.002607 0.000561
Vacuole Periphery 0.000940 0.000156 0.000347 0.000984 0.000068 0.000365 0.000279 0.000106 0.000458 0.000276 0.000311 0.000358

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.31 9.22 6.77 9.71 -0.88 15.65* 17.47* 20.38* 4.64 0.04 7.76 18.67 16.82 9.63 -2.11
Bud Neck 8.83 -3.65 4.92 -2.19 7.49 -9.02 -11.93 -11.53 0.82 6.62 -1.28 -11.66 -2.67 -1.16 9.75
Bud Site 21.97* 9.83 18.92* -3.37 7.99 -2.85 -7.29 -1.76 1.25 6.15 17.15 4.55 16.06 -1.35 10.09
Cell Periphery 7.90 2.98 3.79 -3.30 0.90 -5.56 -7.16 -7.04 -2.35 1.64 1.77 -3.91 -2.86 -4.27 1.12
Cytoplasm 5.30 1.17 5.42 0.75 2.90 -0.34 0.92 2.91 1.91 1.08 3.82 1.29 6.05 1.97 3.06
Cytoplasmic Foci 2.26 -2.72 2.67 0.99 3.56 -1.76 3.46 3.26 3.28 -0.71 -0.62 -2.05 4.37 3.55 3.59
Eisosomes -12.65 -11.12 -18.82 -11.42 -10.56 -14.16 -11.20 -20.13 -6.09 -6.42 -18.97 -15.66 -27.88 -11.98 -11.60
Endoplasmic Reticulum -6.60 -10.49 -3.01 3.39 8.81 -3.20 -5.17 -2.81 0.59 3.73 -7.20 -11.52 -3.88 3.70 9.83
Endosome -2.30 -7.38 3.29 6.11 10.22 -2.86 -3.04 0.96 3.48 3.66 -3.45 -8.00 3.59 6.99 10.77
Golgi -6.43 -6.60 -0.36 5.65 5.98 -0.97 -1.26 2.48 2.86 2.48 -6.02 -6.33 1.84 6.99 7.06
Lipid Particles -6.37 -9.20 0.36 6.71 9.33 -0.29 -2.28 0.35 0.62 2.42 -5.23 -9.02 0.36 5.24 9.05
Mitochondria 3.38 4.43 -1.94 -3.77 -4.24 1.77 0.45 -0.00 -2.23 -0.63 3.73 3.97 -1.14 -4.50 -4.70
Mitotic Spindle 1.58 0.24 1.35 -4.99 2.20 -1.17 1.18 1.87 1.96 0.90 1.33 0.25 1.53 0.99 2.40
None -6.45 -0.34 -2.85 -1.05 -2.79 1.58 1.57 1.55 -0.93 -0.65 1.51 1.57 1.45 -1.01 -2.18
Nuclear Periphery -0.60 -7.95 -2.89 -2.91 2.54 -2.11 -7.61 -6.14 -5.83 2.50 -1.64 -10.98 -5.53 -5.51 4.89
Nuclear Periphery Foci 1.77 -1.98 1.59 -0.45 3.43 0.99 0.56 1.12 1.86 4.04 1.59 -0.80 1.70 1.13 4.27
Nucleolus 1.81 1.76 0.70 -1.42 -1.34 1.04 0.99 0.99 -2.64 0.02 1.49 1.43 1.25 -1.91 -1.42
Nucleus 1.21 1.03 1.14 -3.14 2.41 1.78 1.72 1.78 0.21 4.35 2.15 2.00 2.13 -2.27 4.65
Peroxisomes -1.63 -0.52 1.35 2.75 1.37 3.04 5.02 4.73 3.07 -1.02 1.75 3.36 4.95 4.25 1.10
Vacuole 3.16 -2.74 0.58 -1.32 2.79 -0.54 -3.52 0.12 1.08 4.55 2.27 -4.01 1.18 -0.87 4.99
Vacuole Periphery 2.03 1.48 -0.05 -1.17 -0.89 -1.51 -2.11 -0.82 1.34 1.82 0.90 0.79 0.38 -0.36 -0.22
Standard name
Human Ortholog
Description Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p; associates with actin patches on cell cortex; promotes protein-protein interactions essential for endocytosis; binds to and activates Arp2/3 complex in vitro; phosphorylation of Thr-1225 is regulated by MAPK Hog1p in response to osmotic stress; previously thought to be a subunit of poly(A) ribonuclease
Localization
Cell Percentages actin (79%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Pan1

Pan1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pan1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available