Standard name
Human Ortholog
Description Essential component of the MIND kinetochore complex; joins kinetochore subunits contacting DNA to those contacting microtubules; critical to kinetochore assembly; complex consists of Mtw1p Including Nnf1p-Nsl1p-Dsn1p (MIND)
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Bud 0 0.05 0.07 0.05 0.1 0.08 0.11 0.1 0.11 0.11 0.07 0.1 0 0 0 0.06 – 0 0 0 0 0 0 0
Bud Neck 0 0 0.09 0.08 0.06 0.08 0.08 0.12 0.07 0.07 0 0.07 0.06 0.06 0 0 – 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0.06 0 0.07 0 0.05 0.05 0.05 0.06 0 0 0 0 – 0.12 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Cytoplasm 0.12 0.07 0.07 0.11 0.13 0.08 0.06 0.07 0.11 0.08 0.1 0.06 0.12 0.15 0.28 0.06 – 0.19 0.05 0 0 0.05 0 0.07
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.12 – 0.06 0 0 0 0 0 0
Endosome 0.13 0.19 0.08 0 0 0 0 0 0 0 0 0 0.12 0.1 0.28 0 – 0.19 0.08 0.11 0.08 0.08 0.05 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Mitochondria 0.19 0.19 0 0 0.08 0.08 0.12 0.07 0.2 0.11 0.26 0.26 0 0 0 0.18 – 0.06 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 – 0 0 0 0 0.06 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Nucleolus 0.29 0.08 0.14 0.2 0.23 0.17 0.16 0.15 0.24 0.22 0.26 0.24 0.53 0.29 0.21 0.41 – 0.5 0 0 0 0.06 0.05 0.06
Peroxisomes 0.07 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0.08 0 – 0 0 0 0 0 0 0
SpindlePole 0.63 0.7 0.8 0.73 0.67 0.71 0.77 0.77 0.58 0.69 0.47 0.58 0.88 0.68 0.57 0.71 – 0.69 0.79 0.76 0.81 0.66 0.76 0.68
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 4 0 1 0 3 2 4 2 0 0 0 0 0 0 – 0 0 1 0 0 0 2
Bud 0 16 14 9 17 17 29 25 34 29 13 24 0 2 0 1 – 0 3 1 1 2 5 6
Bud Neck 1 9 19 15 11 18 21 31 20 18 6 17 1 9 1 0 – 0 0 2 2 0 0 2
Bud Site 1 4 5 4 11 9 18 2 16 15 10 15 0 0 0 0 – 2 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Cytoplasm 13 22 14 20 23 17 16 18 34 21 20 14 2 23 44 1 – 3 6 13 7 11 4 15
Endoplasmic Reticulum 0 2 0 0 0 0 0 0 0 1 0 0 0 0 0 2 – 1 0 0 0 0 0 1
Endosome 14 59 16 7 0 8 3 5 3 4 7 2 2 16 43 0 – 3 10 41 22 16 9 9
Golgi 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 – 0 0 0 1 0 0 0
Mitochondria 21 61 4 7 15 17 30 18 62 31 51 64 0 1 0 3 – 1 0 11 0 1 0 4
Nucleus 1 3 4 2 3 5 6 6 8 7 12 8 0 5 3 0 – 0 0 0 0 11 7 8
Nuclear Periphery 2 0 0 2 2 1 5 6 9 6 3 8 0 0 0 0 – 0 0 0 3 1 2 0
Nucleolus 32 24 29 36 41 38 40 39 72 59 51 59 9 45 32 7 – 8 0 7 4 11 9 15
Peroxisomes 8 3 0 6 0 8 1 1 15 3 6 5 0 1 12 0 – 0 0 3 1 2 0 1
SpindlePole 70 222 170 133 118 158 194 197 176 188 93 144 15 106 88 12 – 11 98 295 215 135 139 160
Vac/Vac Membrane 2 1 3 0 1 2 0 0 2 1 1 1 0 2 1 0 – 0 0 1 0 3 1 4
Unique Cell Count 111 315 213 183 177 223 253 257 305 274 196 250 17 155 155 17 16 125 387 267 205 184 236
Labelled Cell Count 165 427 282 242 243 298 366 351 455 385 273 361 29 210 224 26 29 125 387 267 205 184 236


SpindlePole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.9 3.8 5.8 5.5 4.5 5.2 4.8 5.5 4.5 4.9 5.3 4.4 4.8 5.5 5.4 6.0 – 6.9 6.6 7.1 6.9
Std Deviation (1e-4) 1.1 0.5 1.7 1.8 1.4 2.0 1.7 2.2 2.1 2.0 6.0 1.7 0.7 1.1 1.7 1.1 – 2.4 2.5 3.0 2.7
Intensity Change (Log2) – – – -0.07 -0.37 -0.16 -0.26 -0.08 -0.35 -0.24 -0.11 -0.39 -0.28 -0.07 -0.1 0.06 – 0.25 0.18 0.3 0.24


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.4453 4.076 3.8103 3.7322 3.8368 3.528 5.0434 4.7839 5.7672 4.8642 3.744 5.169 2.9242 2.9923 3.1171 3.3592 3.6539 3.0519
Actin 0.0234 0.0013 0.0017 0.0006 0.0051 0.0006 0.0301 0.0006 0.0036 0.0256 0.0002 0.0096 0.0091 0.0004 0.0039 0.0253 0.0165 0.001
Bud 0.0001 0.0003 0.0002 0 0.0003 0 0.0009 0 0.0001 0.0002 0 0.0001 0.0002 0.0003 0.0003 0.0006 0.0001 0.0001
Bud Neck 0.0004 0.0013 0.0074 0.0005 0.0008 0.0005 0.0023 0.0002 0.0006 0.0007 0.0003 0.0002 0.0007 0.0026 0.0023 0.0021 0.0007 0.0013
Bud Periphery 0.0001 0.0005 0.0003 0 0.0002 0.0001 0.0019 0 0.0001 0.0003 0 0.0002 0.0002 0.0005 0.0004 0.0014 0.0001 0.0004
Bud Site 0.0003 0.0118 0.0052 0.0001 0.0016 0.0003 0.0016 0.0002 0.0011 0.0015 0.0003 0.0002 0.0021 0.0088 0.0019 0.0186 0.001 0.0005
Cell Periphery 0 0.001 0.0004 0 0.0001 0 0.0002 0 0 0.0001 0 0 0.0001 0.0001 0.0001 0.0003 0 0
Cytoplasm 0.0014 0.0258 0.0013 0.0002 0.0116 0.0013 0.0063 0.0648 0.0022 0.0003 0.0002 0.0004 0.0022 0.0084 0.0032 0.0005 0.0032 0.0013
Cytoplasmic Foci 0.1619 0.1547 0.1425 0.1172 0.2362 0.1061 0.1169 0.1673 0.139 0.1302 0.1851 0.1035 0.0675 0.0572 0.0306 0.0925 0.1542 0.0491
Eisosomes 0.0001 0.0004 0 0 0 0 0.001 0 0.0001 0.0004 0 0 0.0002 0.0001 0 0.0001 0.0001 0
Endoplasmic Reticulum 0.0006 0.0008 0.0001 0 0.0024 0.0001 0.0018 0.0011 0.0004 0.0002 0 0.0001 0.0006 0.0003 0.0006 0.0006 0.0005 0.0002
Endosome 0.017 0.0164 0.0117 0.0012 0.0873 0.0064 0.016 0.0029 0.0212 0.0082 0.0021 0.0058 0.0078 0.0036 0.0095 0.0072 0.0305 0.0059
Golgi 0.0114 0.0018 0.0039 0.0017 0.0157 0.009 0.0214 0.0013 0.0167 0.0161 0.0021 0.0108 0.0025 0.0014 0.0067 0.0019 0.0101 0.0017
Lipid Particles 0.0215 0.0175 0.0078 0.0095 0.1186 0.0297 0.0259 0.0047 0.0513 0.0743 0.0103 0.0061 0.0198 0.0064 0.0161 0.0038 0.0719 0.0107
Mitochondria 0.006 0.0078 0.0023 0 0.0091 0.0165 0.0041 0 0.0023 0.0219 0 0.0035 0.0021 0.0008 0.0039 0.0007 0.002 0.0006
None 0.0061 0.0055 0.005 0.0002 0.0029 0.0153 0.0682 0.0872 0.0195 0.0006 0.0003 0.0039 0.0115 0.0163 0.0044 0.0005 0.003 0.0025
Nuclear Periphery 0.0007 0.0019 0.0004 0.0006 0.0287 0.0019 0.0051 0.0003 0.0027 0.0005 0.0003 0.0006 0.0022 0.0024 0.0044 0.0019 0.0095 0.0035
Nucleolus 0.0009 0.0247 0.0047 0.0004 0.0014 0.0019 0.0039 0.0006 0.0043 0.0008 0.0011 0.0006 0.0035 0.0226 0.0187 0.003 0.0017 0.0101
Nucleus 0.0182 0.0226 0.0031 0.0002 0.0126 0.013 0.0044 0.0004 0.0015 0.0003 0.0004 0.0003 0.0022 0.0534 0.0152 0.0025 0.0174 0.0088
Peroxisomes 0.0418 0.018 0.0133 0.0127 0.041 0.008 0.0397 0.0212 0.0254 0.0937 0.0186 0.0151 0.0131 0.0118 0.0186 0.0086 0.072 0.0097
Punctate Nuclear 0.6879 0.6819 0.7876 0.8548 0.4196 0.7887 0.6466 0.647 0.7073 0.6233 0.7787 0.8387 0.8517 0.8017 0.8583 0.7864 0.603 0.8908
Vacuole 0.0002 0.0039 0.0008 0 0.003 0.0002 0.001 0.0001 0.0003 0.0003 0 0.0001 0.0003 0.0008 0.0005 0.0308 0.0015 0.0013
Vacuole Periphery 0.0002 0.0002 0.0003 0 0.002 0.0003 0.0007 0 0.0002 0.0003 0 0.0001 0.0002 0.0001 0.0002 0.0106 0.0011 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 6.3414 7.9364 0.8413 5.4123 17.266 8.8731 6.3049 5.0291 6.26 11.3954
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
231 462 1604 392 1343 2121 207 1465 1574 2583 1811 1857

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 719.02 759.92 836.30 886.81 664.89 837.52 861.49 851.44 672.83 823.64 839.18 858.91
Standard Deviation 83.80 115.55 111.04 119.39 79.68 106.80 104.97 117.44 82.55 112.42 110.65 118.73
Intensity Change Log 2 — 0.079816 0.217989 0.302593 — 0.333008 0.373718 0.356789 — 0.207012 0.294908 0.328885

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000472 0.000708 0.000184 0.000117 0.000645 0.000313 0.000378 0.000375 0.000620 0.000384 0.000206 0.000321
Bud Neck 0.006060 0.003877 0.002471 0.004469 0.011344 0.004858 0.002739 0.001391 0.010569 0.004683 0.002502 0.002041
Bud Site 0.003440 0.011573 0.004834 0.006699 0.006205 0.007222 0.003054 0.011873 0.005799 0.008000 0.004631 0.010781
Cell Periphery 0.000141 0.000170 0.000041 0.000016 0.000459 0.000166 0.000174 0.000047 0.000412 0.000167 0.000057 0.000040
Cytoplasm 0.028690 0.027832 0.016662 0.007805 0.080040 0.034123 0.036081 0.008756 0.072504 0.032998 0.018881 0.008555
Cytoplasmic Foci 0.242538* 0.174533 0.004041 0.005993 0.226959* 0.142923 0.016740 0.015731 0.229246* 0.148577 0.005493 0.013675
Eisosomes 0.000121 0.000065 0.000012 0.000006 0.000145 0.000064 0.000120 0.000009 0.000142 0.000064 0.000024 0.000009
Endoplasmic Reticulum 0.000910 0.000992 0.000357 0.000129 0.001414 0.000868 0.001835 0.000239 0.001340 0.000890 0.000526 0.000216
Endosome 0.020106 0.025477 0.001315 0.002454 0.018246 0.018015 0.005155 0.006291 0.018519 0.019350 0.001754 0.005481
Golgi 0.019590 0.025689 0.000551 0.000524 0.017260 0.014038 0.001190 0.003566 0.017602 0.016122 0.000624 0.002924
Lipid Particles 0.069682 0.027710 0.000653 0.000466 0.060390 0.031464 0.003880 0.001471 0.061754 0.030792 0.001022 0.001259
Mitochondria 0.012636 0.002416 0.000227 0.000100 0.003950 0.003763 0.000481 0.001307 0.005225 0.003522 0.000256 0.001052
Mitotic Spindle 0.428563* 0.557431* 0.923709* 0.956612* 0.259854* 0.576822* 0.624857* 0.926144* 0.284614* 0.573354* 0.889550* 0.932576*
None 0.004606 0.003490 0.001847 0.000269 0.023301 0.006470 0.013280 0.000532 0.020557 0.005937 0.003154 0.000476
Nuclear Periphery 0.000367 0.000306 0.000271 0.000349 0.000863 0.000552 0.000591 0.000136 0.000790 0.000508 0.000307 0.000181
Nuclear Periphery Foci 0.058349 0.057057 0.005913 0.003408 0.082531 0.055577 0.024192 0.005416 0.078982 0.055841 0.008002 0.004992
Nucleolus 0.036834 0.016443 0.015193 0.001469 0.113401 0.049507 0.071235 0.002166 0.102164 0.043594 0.021599 0.002018
Nucleus 0.022151 0.008702 0.018214 0.002619 0.053215 0.018007 0.178480* 0.003201 0.048656 0.016343 0.036532 0.003078
Peroxisomes 0.041351 0.052087 0.002239 0.002727 0.034666 0.031875 0.006073 0.005300 0.035647 0.035490 0.002677 0.004757
Vacuole 0.002906 0.003017 0.001192 0.003500 0.004710 0.002314 0.009240 0.003345 0.004445 0.002439 0.002112 0.003378
Vacuole Periphery 0.000487 0.000424 0.000074 0.000268 0.000400 0.001058 0.000224 0.002705 0.000413 0.000944 0.000091 0.002191

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.10 1.10 0.39 2.34 -0.51 1.15 -3.64 -0.54 -2.14 3.41 0.56 -0.84 -0.47 -1.38 0.34
Bud Neck 0.68 -0.29 -0.33 -0.78 -0.20 2.15 -0.67 2.80 1.75 3.11 2.23 0.42 2.28 0.45 2.84
Bud Site -3.18 -2.13 -3.23 -0.18 -2.09 -1.66 -3.14 -5.52 -4.98 0.03 -3.07 -3.37 -6.21 -4.81 -3.70
Cell Periphery -0.73 5.02 5.71 6.07 1.82 3.73 1.25 6.03 7.10 6.92 3.55 5.83 6.58 9.04 2.85
Cytoplasm -1.06 0.19 0.86 1.81 0.86 5.84 1.49 6.26 0.89 2.40 5.22 5.03 6.33 1.65 1.33
Cytoplasmic Foci 4.23 12.98 12.93 13.78 -0.12 9.98 21.08 26.24 20.74 1.23 10.76 31.14 29.43 24.69 -3.99
Eisosomes 3.96 8.28 8.60 8.11 1.61 8.29 -1.66 25.50 21.09 9.16 9.30 18.33 26.67 22.51 7.65
Endoplasmic Reticulum 0.08 1.81 1.34 1.43 0.06 3.69 -4.74 5.69 3.12 6.14 3.38 0.65 5.62 3.33 4.24
Endosome -1.12 6.83 6.15 7.53 -0.53 4.57 3.40 7.78 4.25 2.07 3.24 14.54 9.74 7.31 -2.89
Golgi -0.64 6.31 6.29 8.25 0.11 2.61 10.92 10.25 9.86 1.22 1.65 14.94 12.19 12.85 -1.21
Lipid Particles 4.10 7.61 7.60 7.02 -0.15 8.38 13.37 15.58 11.37 4.26 9.28 17.32 17.34 13.27 0.46
Mitochondria 0.94 1.37 1.43 3.79 4.36 1.52 6.41 4.08 1.75 -0.41 1.62 3.86 3.31 2.62 -0.92
Mitotic Spindle -5.54 -16.98 -18.01 -15.50 -4.09 -21.19* -8.08 -48.36* -27.77* -10.70 -21.66 -41.10 -51.87 -31.79* -7.81
None 1.12 1.52 3.22 2.77 5.77 7.66 3.01 11.21 8.98 3.78 7.78 8.96 11.55 9.40 6.95
Nuclear Periphery 2.39 -2.19 -0.20 -1.18 0.84 5.16 -1.37 7.79 4.37 5.03 5.72 1.61 6.56 2.67 3.96
Nuclear Periphery Foci 0.39 6.00 6.48 7.53 1.81 5.29 5.95 19.58* 18.13* 4.81 5.22 18.00 20.65 19.67 3.76
Nucleolus 4.21 0.92 5.70 3.28 11.21 8.56 0.75 20.20 15.93 7.14 9.64 8.89 20.91 16.18 13.99
Nucleus 2.02 -2.41 0.50 -1.37 2.99 5.88 -5.95 6.20 1.19 6.92 6.28 -4.54 5.68 0.24 8.62
Peroxisomes 0.62 8.59 8.28 10.67 -0.94 3.93 7.94 14.98 13.02 4.15 3.32 18.51 17.18 16.65 -2.11
Vacuole -1.21 -1.57 -2.98 -2.60 -2.74 1.44 -3.75 -4.69 -5.28 0.70 0.83 -2.83 -5.52 -5.90 -4.34
Vacuole Periphery -0.42 1.58 0.31 0.74 -1.53 -0.95 -3.47 -1.67 -1.37 -1.43 -1.02 3.07 -1.66 -1.33 -1.78
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Essential component of the MIND kinetochore complex; joins kinetochore subunits contacting DNA to those contacting microtubules; critical to kinetochore assembly; complex consists of Mtw1p Including Nnf1p-Nsl1p-Dsn1p (MIND)
Localization
Cell Percentages spindle pole (56%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Mtw1

Mtw1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mtw1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available