Standard name
Human Ortholog
Description Mitochondrial peroxiredoxin with thioredoxin peroxidase activity; has a role in reduction of hydroperoxides; reactivation requires Trr2p and glutathione; induced during respiratory growth and oxidative stress; phosphorylated; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 0.12 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0 0 0 0.07 0 0 0.06 0 0.05 0 0.05 0 0 0 0.05 – – – 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Endosome 0.07 0 0.08 0 0.06 0.05 0 0 0 0 0 0 0 0.05 0 – – – 0.05 0 0.06 0 0 0
Golgi 0 0 0.24 0.1 0.18 0.05 0 0.12 0 0 0 0 0 0.16 0.33 – – – 0.05 0.05 0 0.1 0.14 0.11
Mitochondria 0.91 0.97 0.73 0.86 0.69 0.78 0.77 0.68 0.89 0.87 0.88 0.89 0.89 0.86 0.77 – – – 0.84 0.82 0.78 0.65 0.69 0.69
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0.05 0.13 0.07 0.06 0.05 0.06 0 0.09 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0.05 0 0 0 0.05 0.1 0.09 0.08 0.11 0.12 0.07 0.12 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0.09 0 0 0 0 0 0 0 0 0 0 0.05 0.07 – – – 0 0 0.05 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0.18 0.11 0.09 0.06 0.18 0.11 0.09 0.12 0 0 0 0 0 0.11 0.07 – – – 0 0 0 0.05 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 1 0 0 0 1 1 3 0 2 0 2 0 – – – 0 2 1 3 5 5
Bud 0 2 3 3 2 2 7 3 7 6 3 2 0 2 1 – – – 0 0 1 0 2 2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 1 0 0 0 0 0 1 1 1 0 4 0 0 0 – – – – – – – – –
Cell Periphery 1 15 2 6 5 3 1 3 0 4 0 2 1 3 4 – – – 0 0 0 0 0 0
Cytoplasm 1 1 2 10 7 10 19 11 12 9 11 4 2 6 9 – – – 0 0 1 2 0 0
Endoplasmic Reticulum 0 1 4 0 0 2 0 1 0 0 0 0 0 0 3 – – – 0 0 0 1 0 0
Endosome 14 0 11 6 12 12 1 13 0 1 3 2 2 9 3 – – – 9 4 9 3 3 5
Golgi 6 2 33 15 37 14 7 42 1 6 2 5 2 27 56 – – – 9 7 6 8 26 21
Mitochondria 173 124 102 125 142 205 233 233 237 296 184 272 62 150 131 – – – 168 108 128 57 132 136
Nucleus 3 0 0 1 0 1 3 2 4 0 0 0 3 0 0 – – – 0 0 0 0 2 1
Nuclear Periphery 6 5 4 3 11 34 21 20 14 19 5 26 2 2 4 – – – 0 0 1 1 1 2
Nucleolus 9 1 2 2 10 27 27 27 30 39 15 36 3 3 1 – – – 0 0 0 0 3 4
Peroxisomes 1 1 13 5 9 4 7 7 1 4 0 4 2 9 12 – – – 5 5 8 1 3 6
SpindlePole 4 0 2 0 4 2 0 4 0 5 1 3 1 1 1 – – – 0 0 1 0 0 0
Vac/Vac Membrane 34 14 12 9 37 30 28 43 8 15 9 8 3 19 12 – – – 3 3 0 4 7 6
Unique Cell Count 191 128 140 145 206 264 302 345 265 339 209 305 70 174 170 202 133 165 89 192 198
Labelled Cell Count 252 167 190 186 276 346 354 411 316 408 233 370 83 233 237 202 133 165 89 192 198


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.2 6.6 8.9 8.3 12.0 11.6 12.4 14.4 11.0 13.2 12.0 12.7 9.2 11.3 11.6 – – – 15.9 14.4 13.8
Std Deviation (1e-4) 1.7 1.2 1.9 1.8 3.5 2.9 3.6 4.7 4.1 4.7 5.0 5.7 4.4 6.3 5.0 – – – 16.0 13.7 12.5
Intensity Change (Log2) – – – -0.1 0.43 0.38 0.48 0.69 0.31 0.57 0.43 0.52 0.05 0.34 0.39 – – – 0.84 0.7 0.64


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Bud 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Cytoplasm 2.3 0 0 2.2 0 0 0 1.9 0 0 0 0 – – –
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Endosome -1.3 -0.7 -1.4 0 -1.9 0 0 -3.0 0 0 -1.0 -2.6 – – –
Golgi -3.0 -1.3 -5.4 -7.2 -3.1 -8.0 -7.9 -6.9 -7.7 -3.8 -1.8 1.8 – – –
Mitochondria 2.8 -0.8 1.1 1.0 -1.1 4.3 3.8 3.6 4.4 2.6 3.0 0.9 – – –
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Nuclear Periphery 0 1.1 3.3 1.7 1.4 1.1 1.3 0 2.2 0 0 0 – – –
Nucleolus 0 0 3.3 3.0 2.7 3.5 3.6 2.4 3.6 0 0 0 – – –
Peroxisomes -2.0 -1.8 -3.7 -3.3 -3.6 0 0 -4.5 -4.1 -1.7 -1.4 -0.7 – – –
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Vacuole -0.8 2.5 0.9 0.2 1.2 -2.5 -1.8 -1.6 -2.8 -1.1 0.7 -0.5 – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 7.7578 8.0415 7.3111 7.9819 7.1009 8.0702 11.4241 11.7669 10.7165 9.414 9.809 11.322 8.2679 8.9635 8.2059 7.1154 6.6621 8.5131
Actin 0.022 0.018 0.0247 0.0001 0.0163 0.0024 0.0051 0.004 0.0025 0.0001 0.0001 0.0006 0.0167 0.0052 0.0164 0.0053 0.0261 0.0004
Bud 0.0004 0.0017 0.0004 0 0.0005 0.0001 0.0001 0.0001 0 0 0 0 0.0004 0.0001 0.0002 0.0002 0.0002 0
Bud Neck 0.0003 0.0002 0.0002 0 0.0001 0.0024 0 0 0 0 0 0.0001 0.0004 0.0001 0.0005 0.0005 0.0003 0
Bud Periphery 0.0007 0.0048 0.0004 0 0.0005 0.0001 0.0001 0.0001 0.0001 0 0.0001 0 0.001 0.0002 0.0003 0.0005 0.0004 0
Bud Site 0.0013 0.0047 0.0024 0 0.001 0.0002 0.0001 0.0003 0.0001 0 0 0 0.0043 0.0007 0.0017 0.004 0.0004 0
Cell Periphery 0.0002 0.0006 0.0001 0 0.0001 0.0001 0.0001 0 0 0 0 0 0.0002 0.0001 0.0001 0.0003 0.0002 0
Cytoplasm 0.0007 0.0001 0.0047 0 0.0001 0.0001 0 0 0 0 0 0 0.0013 0 0.0029 0.0008 0.0007 0.0001
Cytoplasmic Foci 0.0116 0.0018 0.0172 0.0001 0.0065 0.0016 0.0012 0.001 0.0019 0 0.0002 0.0087 0.0192 0.003 0.0071 0.0039 0.0017 0.0005
Eisosomes 0.0003 0.0003 0.0008 0 0.0001 0.0001 0.0003 0.0001 0.0001 0 0.0001 0.0001 0.0002 0.0001 0.0002 0.0005 0.0003 0.0001
Endoplasmic Reticulum 0.0008 0.0001 0.0052 0 0.0001 0 0 0 0 0 0 0 0.0013 0.0001 0.0013 0.0049 0.0046 0.0003
Endosome 0.0117 0.0079 0.0241 0.0001 0.0118 0.0041 0.0027 0.0011 0.0032 0.0001 0.0007 0.0006 0.0376 0.0037 0.0108 0.0113 0.0168 0.0116
Golgi 0.0132 0.0174 0.0091 0.0011 0.0323 0.0071 0.005 0.0041 0.0146 0.0001 0.001 0.0019 0.0245 0.0101 0.004 0.0091 0.0065 0.0057
Lipid Particles 0.03 0.0038 0.0164 0.0001 0.0052 0.0021 0.0143 0.0006 0.0081 0.0004 0.0005 0.0061 0.0248 0.0121 0.0095 0.0153 0.011 0.0192
Mitochondria 0.8658 0.9172 0.8572 0.9966 0.9066 0.976 0.9542 0.9773 0.9586 0.9977 0.9943 0.9713 0.8264 0.927 0.9076 0.9234 0.9059 0.9518
None 0.0004 0.0001 0.001 0 0 0 0 0 0 0 0 0 0.001 0 0.0129 0.0055 0.0009 0
Nuclear Periphery 0.0028 0.0001 0.0027 0 0.0002 0 0 0 0 0 0 0.0002 0.0099 0.0003 0.0025 0.0051 0.008 0.0013
Nucleolus 0.0003 0.0025 0.0005 0 0 0.0001 0.0001 0 0 0 0 0 0.0005 0.0002 0.0003 0.0007 0.0005 0.0002
Nucleus 0.0111 0.0005 0.0006 0 0.0001 0.0001 0 0 0 0 0 0 0.0076 0.0001 0.0007 0.0007 0.0017 0.0001
Peroxisomes 0.021 0.0086 0.0121 0.0014 0.0074 0.0021 0.014 0.0105 0.0097 0.0012 0.0024 0.0022 0.0083 0.0141 0.0093 0.0039 0.0021 0.0035
Punctate Nuclear 0.001 0 0.0047 0 0.0001 0.0001 0 0 0 0 0 0.0001 0.0042 0 0.0012 0.0005 0.0013 0
Vacuole 0.0016 0.0061 0.0027 0.0001 0.0013 0.0006 0.0006 0.0001 0.0002 0.0001 0.0001 0.0003 0.0038 0.003 0.0019 0.002 0.004 0.0015
Vacuole Periphery 0.0029 0.0035 0.0126 0.0003 0.0097 0.0006 0.002 0.0004 0.0007 0.0002 0.0003 0.0077 0.0063 0.0197 0.0089 0.0017 0.0063 0.0036

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 42.1147 35.1381 54.0104 66.7811 40.0426 64.5401 49.4855 65.086 76.4423 57.9161
Translational Efficiency 1.5313 1.8256 1.6063 1.6995 1.956 1.5093 1.4783 1.7234 1.8438 1.6397

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
54 1119 289 1869 2001 2485 211 1773 2055 3604 500 3642

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1706.98 855.66 1288.74 1842.66 852.84 1013.90 1574.51 1627.62 875.28 964.77 1409.33 1737.97
Standard Deviation 574.95 167.14 240.80 580.91 141.00 185.30 297.99 385.49 216.13 194.19 301.51 507.02
Intensity Change Log 2 — -0.996337 -0.405485 0.110344 — 0.249568 0.884556 0.932417 — -0.453344 0.161611 0.439010

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.005365 0.007111 0.008054 0.006701 0.001170 0.002943 0.012362 0.004051 0.001280 0.004237 0.009872 0.005411
Bud Neck 0.006297 0.004945 0.005638 0.001145 0.001605 0.000690 0.010600 0.000943 0.001728 0.002011 0.007732 0.001047
Bud Site 0.007280 0.010184 0.004556 0.003692 0.004973 0.002263 0.009374 0.001356 0.005034 0.004722 0.006589 0.002555
Cell Periphery 0.000223 0.000910 0.000182 0.000256 0.000311 0.000442 0.000223 0.000273 0.000309 0.000587 0.000199 0.000264
Cytoplasm 0.021034 0.002216 0.000669 0.000591 0.001295 0.000637 0.001336 0.000349 0.001814 0.001127 0.000951 0.000473
Cytoplasmic Foci 0.040129 0.019539 0.046821 0.005694 0.017090 0.010857 0.054393 0.010067 0.017695 0.013553 0.050016 0.007823
Eisosomes 0.000413 0.000220 0.000247 0.000793 0.000044 0.000065 0.000562 0.000560 0.000054 0.000113 0.000380 0.000680
Endoplasmic Reticulum 0.017119 0.000349 0.000390 0.000127 0.000235 0.000088 0.000360 0.000151 0.000679 0.000169 0.000378 0.000139
Endosome 0.025783 0.039882 0.035181 0.001531 0.029398 0.016113 0.021224 0.002415 0.029303 0.023493 0.029291 0.001961
Golgi 0.022888 0.030553 0.074191 0.015378 0.022133 0.018916 0.043265 0.026642 0.022153 0.022529 0.061140 0.020862
Lipid Particles 0.036058 0.007350 0.008996 0.001569 0.006058 0.001629 0.009712 0.002342 0.006846 0.003406 0.009299 0.001945
Mitochondria 0.458626* 0.808790* 0.733337* 0.939766* 0.877983* 0.922896* 0.726432* 0.928167* 0.866963* 0.887467* 0.730423* 0.934119*
Mitotic Spindle 0.047366 0.003441 0.021866 0.000782 0.004715 0.000851 0.021865 0.000534 0.005836 0.001655 0.021865 0.000661
None 0.003990 0.000682 0.000972 0.001610 0.000261 0.000205 0.001406 0.001874 0.000359 0.000353 0.001155 0.001739
Nuclear Periphery 0.008614 0.000055 0.001564 0.000240 0.000104 0.000030 0.002128 0.000217 0.000328 0.000038 0.001802 0.000229
Nuclear Periphery Foci 0.061763 0.000210 0.001468 0.000102 0.000202 0.000052 0.001407 0.000137 0.001819 0.000101 0.001442 0.000119
Nucleolus 0.022303 0.000747 0.000684 0.000376 0.000129 0.000201 0.000791 0.000292 0.000712 0.000371 0.000729 0.000335
Nucleus 0.083028 0.000823 0.000164 0.000121 0.000234 0.000207 0.000216 0.000046 0.002410 0.000398 0.000186 0.000084
Peroxisomes 0.009465 0.054228 0.024530 0.008009 0.022249 0.016253 0.062001 0.007457 0.021913 0.028044 0.040343 0.007741
Vacuole 0.094768 0.004910 0.015043 0.004290 0.004510 0.002583 0.010355 0.003864 0.006882 0.003306 0.013065 0.004083
Vacuole Periphery 0.027486 0.002851 0.015446 0.007224 0.005301 0.002080 0.009989 0.008264 0.005884 0.002319 0.013143 0.007731

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.95 -1.25 -0.75 0.26 0.72 -2.87 -4.42 -4.11 -1.30 3.18 -5.17 -6.07 -6.31 -1.49 2.92
Bud Neck 1.13 0.82 3.03 4.10 4.84 2.57 -5.49 1.85 -1.12 5.97 -0.58 -6.52 2.06 2.88 7.66
Bud Site -0.13 1.32 1.53 3.41 0.64 2.49 -2.06 3.42 1.13 3.99 0.33 -1.13 2.40 2.58 3.65
Cell Periphery -2.57 0.79 -0.15 2.61 -1.80 -0.65 1.36 0.27 0.74 -0.39 -1.71 1.93 0.51 1.94 -1.02
Cytoplasm 2.73 2.95 2.96 2.29 0.24 1.54 -0.12 2.34 1.23 3.79 1.45 2.17 3.17 2.37 2.87
Cytoplasmic Foci 2.17 -0.51 3.61 7.85 7.95 4.00 -5.72 4.44 0.61 6.85 2.75 -7.69 7.13 5.83 10.42
Eisosomes 1.66 1.29 -3.15 -6.63 -5.61 -2.78 -7.27 -10.18 -9.69 0.02 -5.73 -7.52 -12.79 -11.38 -4.61
Endoplasmic Reticulum 3.67 3.66 3.72 3.21 6.04 5.02 -2.14 1.95 -1.85 3.37 3.71 2.13 3.95 1.03 6.46
Endosome -1.16 -0.63 3.05 12.31 7.91 5.92 1.97 13.69 11.88 5.29 2.59 0.00 14.27 17.07 9.44
Golgi -1.45 -5.05 1.09 5.22 6.61 1.67 -3.38 -1.77 -3.15 2.59 -0.21 -6.63 0.66 0.95 6.88
Lipid Particles 1.69 1.58 2.06 4.71 4.27 4.60 -1.60 3.78 -1.80 3.47 3.14 -1.51 4.73 3.15 5.47
Mitochondria -6.34 -4.95 -8.53 -13.02 -10.55 -6.64 6.32 -7.21 -0.89 -8.50 -3.02 8.51 -10.45 -9.45 -13.50
Mitotic Spindle 2.35 1.44 2.48 2.97 4.98 5.45 -3.50 5.92 2.08 4.40 4.62 -4.81 5.93 3.23 6.65
None 2.27 2.08 1.61 -4.18 -4.44 1.12 -6.72 -10.74 -10.80 -2.10 -0.04 -7.52 -14.44 -12.57 -4.52
Nuclear Periphery 3.48 2.84 3.40 -2.97 4.19 4.00 -3.56 -3.56 -7.00 3.36 3.97 -4.79 1.22 -5.54 5.22
Nuclear Periphery Foci 4.03 3.95 4.04 2.89 3.17 4.19 -2.77 1.62 -3.87 2.92 3.76 0.91 3.72 -1.05 4.28
Nucleolus 3.66 3.67 3.72 1.05 0.95 -0.74 -3.67 -1.78 -0.73 2.54 1.89 0.34 2.20 0.25 1.95
Nucleus 4.02 4.05 4.05 2.42 0.50 0.20 0.15 1.93 1.74 2.43 3.21 3.61 3.76 2.78 1.96
Peroxisomes -8.33 -2.58 0.79 10.04 3.41 2.38 -3.85 6.28 4.66 5.36 -2.30 -3.35 6.54 10.48 6.28
Vacuole 4.87 4.34 4.90 0.64 3.92 2.92 -3.30 0.79 -1.74 3.57 4.30 -3.22 3.22 -1.27 5.12
Vacuole Periphery 3.36 1.42 2.70 -4.48 2.92 5.10 -2.42 -2.69 -6.17 0.83 5.69 -4.02 -2.17 -7.71 2.93
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial peroxiredoxin with thioredoxin peroxidase activity; has a role in reduction of hydroperoxides; reactivation requires Trr2p and glutathione; induced during respiratory growth and oxidative stress; phosphorylated; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages mitochondrion (96%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Prx1

Prx1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Prx1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available