Standard name
Human Ortholog
Description Synthase subunit of trehalose-6-P synthase/phosphatase complex; synthesizes the storage carbohydrate trehalose, which is critically important for survival of long-term desiccation; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway; protein abundance increases in response to DNA replication stress and in response to prolonged exposure to boric acid
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0.06 0.06 0.07 0.08 0 0 0 0 0.05 0 0 0 0 0 0 0
Cytoplasm 0.99 0.98 0.98 0.98 0.92 0.95 0.82 0.77 0.79 0.76 0.72 0.71 0.99 0.99 0.99 0.93 0.93 0.96 0.95 0.96 0.88 0.93 0.91 0.92
Endoplasmic Reticulum 0 0 0 0 0.05 0 0.13 0.17 0.12 0.12 0.11 0.13 0 0 0 0 0 0 0 0 0.05 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0.07 0.08 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 2 4 5 9 6 11 9 0 0 0 0 0 0 0 2 1 0 3 0
Bud 0 0 0 0 0 0 2 1 1 0 2 1 0 0 1 1 0 2 0 0 1 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 9 7 3 8 11 7 13 15 14 13 18 3 2 6 8 14 12 0 0 1 0 0 0
Cytoplasm 232 254 260 126 197 246 220 234 202 164 125 169 197 284 291 230 260 269 230 247 241 153 217 144
Endoplasmic Reticulum 2 4 4 0 10 7 36 53 31 26 20 31 2 3 5 8 12 7 1 2 13 3 7 4
Endosome 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 1
Golgi 0 0 0 0 1 1 1 3 6 4 2 7 0 0 0 3 5 0 0 0 3 0 1 1
Mitochondria 1 0 0 1 1 3 1 4 8 3 13 18 0 1 0 4 2 0 0 0 1 0 0 0
Nucleus 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 1 0 1 0 0 1 0 0
Nuclear Periphery 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1
Nucleolus 0 0 0 0 0 0 1 0 1 1 1 2 0 0 0 0 1 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 1 0 4 0 2 10 3 9 4 6 1 0 0 9 15 3 2 1 1 1 1 0
Unique Cell Count 234 259 265 128 214 259 268 305 255 216 174 238 199 287 295 246 281 279 242 258 273 166 238 156
Labelled Cell Count 237 267 273 130 221 270 276 324 276 227 191 261 203 290 304 263 310 293 242 258 273 166 238 156


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 20.9 36.4 30.9 31.0 36.7 37.4 39.5 38.7 41.0 42.8 40.4 44.8 41.8 59.6 64.8 35.6 41.7 45.1 22.4 24.2 28.3
Std Deviation (1e-4) 4.5 8.4 11.0 11.4 11.3 9.7 12.2 12.2 13.6 16.9 16.6 19.6 13.1 21.9 27.8 13.4 13.0 13.5 6.6 5.7 8.1
Intensity Change (Log2) – – – 0.0 0.25 0.27 0.35 0.32 0.41 0.47 0.39 0.54 0.44 0.95 1.07 0.2 0.43 0.54 -0.47 -0.35 -0.13

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700020406080WT3HU80HU120HU160020406080WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3020406080WT1AF100AF140AF180020406080
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0.7 1.0 0 1.0 1.8 2.1 2.4 2.5 0 0 -0.5 0.4 1.4 1.1
Cytoplasm 0.2 -3.1 -2.0 -6.2 -7.5 -6.8 -7.5 -8.2 -8.6 0.8 0.8 0.5 -2.6 -3.1 -1.2
Endoplasmic Reticulum 0 2.0 1.0 5.2 6.3 4.8 4.7 4.5 5.1 0 0 0 1.3 1.9 0.8
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 4.5 4.6 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 2.5 0 0 0 0 0 0 0 0 3.4 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 33.8124 44.4769 39.5281 36.5198 37.4122 41.5602 32.2716 43.6869 39.4567 40.2931 21.3442 37.6519 48.0105 51.2604 46.3155 40.9043 38.1426 48.1277
Actin 0.027 0.0001 0.0064 0.0107 0.0054 0.0011 0.0127 0.0001 0.0006 0 0.0206 0.0091 0.0075 0.0038 0.0007 0.0038 0.0118 0.0003
Bud 0.0015 0.0001 0.0003 0.0011 0.0021 0.0003 0.0011 0 0.0015 0.0001 0.0004 0.0012 0.0001 0.0002 0.0004 0.0012 0.0053 0.0001
Bud Neck 0.0023 0.0002 0.0004 0.0007 0.0008 0.0015 0.0009 0.0001 0.0003 0.0002 0.0006 0.0008 0.0003 0.0001 0.0003 0.0005 0.0005 0.0004
Bud Periphery 0.0017 0.0001 0.0004 0.0011 0.0019 0.0002 0.0022 0 0.0004 0 0.0004 0.001 0.0001 0.0002 0.0004 0.0011 0.0033 0
Bud Site 0.0026 0.0001 0.0006 0.0004 0.0075 0.0001 0.0019 0 0.0011 0 0.0011 0.0009 0.0002 0.0003 0.0003 0.0015 0.0125 0
Cell Periphery 0.0007 0.0002 0.0008 0.0007 0.0009 0.0003 0.0011 0 0.0004 0 0.0001 0.0001 0.0001 0 0.0004 0.0002 0.0002 0
Cytoplasm 0.7892 0.9864 0.9043 0.9034 0.805 0.9004 0.7904 0.9979 0.9239 0.9919 0.5911 0.9312 0.9332 0.9647 0.9289 0.8985 0.8619 0.987
Cytoplasmic Foci 0.0299 0.0028 0.0137 0.0078 0.0244 0.0087 0.0146 0.0004 0.0183 0.0015 0.079 0.0069 0.0039 0.0036 0.0078 0.0155 0.0262 0.0016
Eisosomes 0.0006 0 0.0002 0.0003 0.0008 0 0.0003 0 0 0 0.0001 0 0 0.0001 0.0002 0.0001 0.0001 0
Endoplasmic Reticulum 0.009 0.0017 0.0057 0.0086 0.0041 0.0082 0.0262 0.0002 0.0023 0.0004 0.0191 0.0016 0.006 0.0004 0.0082 0.0073 0.0041 0.006
Endosome 0.014 0.0008 0.0073 0.0053 0.0215 0.0155 0.0272 0.0002 0.0124 0.0017 0.0999 0.0058 0.0171 0.0009 0.0065 0.0062 0.009 0.0012
Golgi 0.003 0 0.0036 0.0008 0.0073 0.0021 0.0099 0 0.0017 0 0.0129 0.0046 0.0054 0.0018 0.0005 0.002 0.0044 0.0001
Lipid Particles 0.0073 0.0001 0.0073 0.0023 0.0399 0.0026 0.004 0 0.0009 0 0.039 0.0021 0.0025 0.0096 0.0034 0.0013 0.0065 0
Mitochondria 0.0108 0 0.0082 0.0013 0.0403 0.0184 0.0277 0 0.0198 0.0001 0.0035 0.0038 0.0037 0.0111 0.0082 0.049 0.0194 0.0001
None 0.0106 0.0003 0.0029 0.0104 0.0034 0.0005 0.0112 0.0001 0.0043 0.0003 0.0083 0.0003 0.0008 0.0003 0.0082 0.0019 0.0075 0.0002
Nuclear Periphery 0.0165 0.0011 0.0065 0.0053 0.0034 0.0054 0.032 0.0002 0.001 0.0008 0.0746 0.0013 0.0049 0.0004 0.0041 0.0011 0.0024 0.0009
Nucleolus 0.0066 0 0.0011 0.0002 0.0056 0.004 0.0015 0 0.0003 0 0.0016 0.0211 0.0001 0 0.0024 0.0002 0.0008 0
Nucleus 0.0142 0.0014 0.007 0.0053 0.0055 0.0046 0.0128 0.0004 0.0016 0.0014 0.0094 0.0037 0.0047 0.0007 0.0038 0.0012 0.0034 0.0012
Peroxisomes 0.0026 0 0.0015 0.0022 0.003 0.0012 0.0008 0 0.0005 0 0.0083 0.0012 0.0008 0.0014 0.0019 0.0028 0.0094 0
Punctate Nuclear 0.0197 0.0001 0.0017 0.0031 0.0008 0.0007 0.0045 0 0.0004 0 0.0199 0.0015 0.0002 0.0001 0.0007 0.0001 0.0062 0.0001
Vacuole 0.0223 0.004 0.0112 0.0213 0.0101 0.0163 0.0135 0.0003 0.0065 0.0012 0.0054 0.0012 0.007 0.0003 0.0089 0.0029 0.0037 0.0005
Vacuole Periphery 0.0081 0.0005 0.009 0.0077 0.0063 0.008 0.0035 0.0001 0.0016 0.0003 0.0046 0.0005 0.0013 0.0002 0.0036 0.0013 0.0013 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 66.7382 45.7392 80.1782 140.3026 85.5675 131.1791 86.9642 128.4731 197.0533 106.8383
Translational Efficiency 2.2837 2.2216 1.9841 2.104 2.2195 1.9921 1.9793 1.9436 1.7251 1.7764

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
140 1203 587 1519 2495 1967 2730 1133 2635 3170 3317 2652

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1791.10 1613.53 5228.98 4132.07 1687.55 1690.05 4163.73 4139.46 1693.05 1661.01 4352.24 4135.23
Standard Deviation 415.38 371.12 1174.31 1209.88 333.01 343.70 992.84 1187.87 338.69 356.30 1104.81 1200.53
Intensity Change Log 2 — -0.150625 1.545684 1.206019 — 0.002136 1.302946 1.294512 — -0.074497 1.433014 1.249627

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000279 0.000274 0.000136 0.000278 0.000042 0.000164 0.000025 0.000275 0.000055 0.000206 0.000045 0.000276
Bud Neck 0.000504 0.000534 0.002845 0.001454 0.000201 0.000393 0.000570 0.002231 0.000217 0.000446 0.000973 0.001786
Bud Site 0.020984 0.009767 0.004348 0.010784 0.004882 0.009165 0.001719 0.010258 0.005738 0.009394 0.002184 0.010559
Cell Periphery 0.003035 0.000342 0.015180 0.006339 0.000155 0.000178 0.000637 0.013264 0.000308 0.000240 0.003211 0.009298
Cytoplasm 0.711699 0.925067 0.730407 0.839762 0.946581 0.919945 0.903733 0.761055 0.934101 0.921889 0.873060 0.806136
Cytoplasmic Foci 0.083105 0.020160 0.027001 0.006378 0.021874 0.027238 0.004234 0.008723 0.025127 0.024552 0.008263 0.007380
Eisosomes 0.000002 0.000002 0.000003 0.000003 0.000001 0.000001 0.000000 0.000004 0.000001 0.000001 0.000001 0.000003
Endoplasmic Reticulum 0.006936 0.000835 0.000159 0.000191 0.000587 0.000611 0.000081 0.000133 0.000924 0.000696 0.000095 0.000166
Endosome 0.006870 0.002116 0.000816 0.000928 0.000760 0.002246 0.000347 0.001254 0.001085 0.002197 0.000430 0.001067
Golgi 0.101456 0.008308 0.035104 0.007230 0.007139 0.010146 0.003279 0.010960 0.012150 0.009449 0.008911 0.008824
Lipid Particles 0.003701 0.001843 0.012878 0.010299 0.000517 0.000764 0.001047 0.020308 0.000686 0.001173 0.003141 0.014575
Mitochondria 0.000031 0.000602 0.000137 0.000145 0.000123 0.000367 0.000103 0.000233 0.000118 0.000456 0.000109 0.000182
Mitotic Spindle 0.003028 0.001424 0.004041 0.001815 0.001120 0.005330 0.001631 0.001127 0.001221 0.003848 0.002057 0.001521
None 0.000584 0.001955 0.002677 0.002008 0.001593 0.000963 0.001675 0.002023 0.001539 0.001339 0.001853 0.002015
Nuclear Periphery 0.000046 0.000040 0.001307 0.000133 0.000016 0.000040 0.000146 0.000218 0.000017 0.000040 0.000351 0.000169
Nuclear Periphery Foci 0.004732 0.002829 0.013261 0.003144 0.000824 0.001481 0.001807 0.004695 0.001031 0.001993 0.003834 0.003807
Nucleolus 0.000021 0.000204 0.000118 0.000134 0.000027 0.000040 0.000112 0.000182 0.000027 0.000102 0.000113 0.000155
Nucleus 0.002581 0.006784 0.041382 0.020464 0.003940 0.004455 0.025669 0.019165 0.003868 0.005339 0.028450 0.019909
Peroxisomes 0.000100 0.000214 0.000022 0.000108 0.000062 0.000128 0.000033 0.000077 0.000064 0.000161 0.000031 0.000095
Vacuole 0.016661 0.012561 0.084954 0.082710 0.004673 0.011279 0.045743 0.135707 0.005310 0.011766 0.052682 0.105352
Vacuole Periphery 0.033642 0.004137 0.023226 0.005693 0.004884 0.005066 0.007407 0.008110 0.006412 0.004713 0.010206 0.006726

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.01 1.79 -0.36 -0.37 -1.93 -4.36 1.17 -4.59 -1.89 -4.68 -5.78 -1.06 -5.08 -1.62 -4.98
Bud Neck -0.44 -7.95 -7.24 -7.71 4.29 -3.89 -8.22 -8.07 -7.37 -5.41 -5.37 -11.67 -12.23 -10.66 -4.09
Bud Site 2.94 4.39 2.35 -1.21 -5.10 -5.67 7.46 -4.42 -0.80 -6.81 -5.61 7.78 -5.52 -1.57 -9.29
Cell Periphery 4.25 -6.95 -4.12 -12.44 5.24 -1.22 -5.76 -11.56 -11.53 -11.02 1.60 -9.25 -16.23 -16.39 -8.99
Cytoplasm -7.62 0.29 -3.67 14.61 -8.23 6.56 16.57 24.89 20.43 16.60 3.47 18.52 26.68 24.26 11.11
Cytoplasmic Foci 5.86 4.75 7.10 8.42 10.54 -3.09 15.40 9.09 10.72 -5.80 0.27 12.10 12.94 14.11 1.63
Eisosomes 0.52 -2.40 -1.15 -1.89 1.41 -6.15 0.54 -7.04 -5.75 -7.10 -4.78 -5.57 -9.21 -5.79 -7.65
Endoplasmic Reticulum 2.02 2.25 2.24 3.60 -0.67 -0.14 4.55 4.17 4.11 -1.87 1.07 4.29 3.91 5.23 -2.21
Endosome 3.75 4.87 4.77 3.03 -0.11 -6.38 4.19 -1.38 3.12 -2.64 -5.40 5.58 0.29 4.62 -2.83
Golgi 6.50 4.61 6.59 1.32 12.27 -2.93 6.45 -2.87 0.19 -7.78 2.33 2.88 3.57 1.54 1.14
Lipid Particles 2.01 -6.79 -6.01 -9.30 2.12 -2.28 -5.00 -11.81 -11.63 -11.23 -2.98 -10.09 -16.08 -15.31 -12.00
Mitochondria -1.61 -10.30 -3.17 1.17 -0.49 -1.85 0.26 -1.69 0.91 -1.74 -2.14 -0.83 -2.15 1.55 -1.96
Mitotic Spindle 1.36 -0.83 1.01 -0.54 1.85 -5.01 -2.75 -0.38 4.64 1.95 -4.80 -3.33 -0.91 3.76 2.03
None -3.75 -9.19 -3.49 0.01 1.74 2.08 -0.20 -0.45 -1.76 -0.38 0.66 -0.96 -0.88 -1.74 -0.22
Nuclear Periphery 0.30 -11.11 -5.42 -6.39 10.14 -3.03 -11.39 -13.11 -10.59 -1.54 -3.81 -14.84 -14.26 -11.34 7.65
Nuclear Periphery Foci 1.19 -5.17 0.91 -0.91 8.42 -2.66 -5.85 -12.02 -8.30 -6.84 -4.50 -10.43 -12.97 -6.74 0.78
Nucleolus -2.12 -11.30 -6.93 0.77 -0.38 -3.55 -17.77 -3.86 -3.55 -1.40 -2.29 -20.35 -6.50 -1.48 -1.38
Nucleus -5.34 -14.73 -14.03 -12.15 6.66 -1.54 -22.93 -14.49 -14.15 4.94 -4.56 -26.91 -19.73 -18.48 6.90
Peroxisomes -2.25 3.63 -0.14 2.27 -5.04 -5.31 4.22 -1.09 3.55 -3.63 -4.87 5.19 -2.48 3.29 -5.76
Vacuole 0.86 -10.61 -13.37 -17.68 -0.29 -6.43 -20.88 -23.44 -22.15 -14.67 -7.93 -24.61 -30.11 -28.00 -13.39
Vacuole Periphery 3.64 1.35 3.49 -1.47 7.80 -0.20 -3.19 -2.59 -2.28 -0.10 2.11 -3.96 0.30 -2.35 5.27
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Synthase subunit of trehalose-6-P synthase/phosphatase complex; synthesizes the storage carbohydrate trehalose, which is critically important for survival of long-term desiccation; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway; protein abundance increases in response to DNA replication stress and in response to prolonged exposure to boric acid
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-7

Tps1

Tps1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tps1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available