Standard name
Human Ortholog
Description Glycolytic enzyme phosphoglucose isomerase; catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate; required for cell cycle progression and completion of the gluconeogenic events of sporulation
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0.05 – 0.07 0.06 0.07 0.07 0 0 0 0 0.06 0.05 0 0 0 0 0 0
Cytoplasm 1.0 1.0 0.99 1.0 0.99 0.98 0.96 – 0.93 0.89 0.88 0.92 1.0 0.99 0.99 1.0 0.99 0.99 0.98 0.95 0.95 0.91 0.95 0.97
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0.07 0.08 0 0 0 0 0 0.08 0.07 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0
Bud 1 0 1 2 2 1 3 – 3 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 4 3 4 7 15 20 – 27 30 31 36 0 0 1 2 9 9 0 0 0 0 0 0
Cytoplasm 252 151 133 308 367 483 419 – 378 459 372 469 115 196 221 110 152 184 236 152 123 64 92 178
Endoplasmic Reticulum 0 0 1 0 1 3 5 – 15 38 35 19 0 1 0 3 13 13 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0
Golgi 0 0 0 0 1 0 0 – 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 1 3 0 0 0 1
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 – 0 0 0 1 0 0 1 0 1 1 0 2 0 0 0 0
Unique Cell Count 253 151 134 309 371 493 438 408 515 424 509 115 197 223 110 153 186 241 161 130 71 97 184
Labelled Cell Count 254 155 138 314 378 502 447 423 530 442 525 115 197 225 115 176 207 241 161 130 71 97 184


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 288.1 356.8 271.2 274.9 266.9 241.5 227.0 – 200.4 197.7 182.3 187.9 306.7 331.8 315.3 398.5 402.8 371.9 215.1 265.7 286.8
Std Deviation (1e-4) 46.2 67.9 48.5 59.1 58.2 45.5 50.2 – 51.9 47.0 48.6 47.2 81.6 71.6 76.1 77.2 98.8 88.1 74.2 84.0 81.9
Intensity Change (Log2) – – – 0.02 -0.02 -0.17 -0.26 – -0.44 -0.46 -0.57 -0.53 0.18 0.29 0.22 0.56 0.57 0.46 -0.33 -0.03 0.08

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000200400WT3HU80HU120HU1600200400WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30200400WT1AF100AF140AF1800200400
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 1.2 – 1.9 1.7 2.1 2.1 0 0 0 0 1.5 1.2
Cytoplasm 0.6 -0.3 -1.0 -2.0 – -2.9 -3.7 -4.0 -3.0 0.9 0.3 -0.2 0.9 0.1 -0.3
Endoplasmic Reticulum 0 0 0 0 – 0 2.9 3.1 0 0 0 0 0 3.0 2.7
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 275.518 344.8553 306.8002 288.3701 259.1011 309.2865 262.9257 359.0397 312.3092 329.2102 286.6066 367.8732 247.8109 329.8006 291.6593 278.5254 227.3762 261.3002
Actin 0.0024 0.0002 0.0001 0.0005 0.0004 0.0002 0.0104 0.0001 0.0004 0.0001 0.0047 0.0002 0.0045 0.0001 0.0249 0.0285 0.0616 0.0035
Bud 0.0014 0.0001 0.001 0.0001 0.0015 0.0001 0.0007 0.0001 0.0002 0.0001 0.002 0.0002 0.0026 0 0.0016 0.0008 0.0036 0.0004
Bud Neck 0.0005 0.0002 0.0004 0.0003 0.0006 0.0009 0.0002 0.0001 0.0001 0.0002 0.0006 0.0003 0.0007 0.0001 0.0004 0.0002 0.0029 0.0007
Bud Periphery 0.0008 0 0.0004 0 0.0013 0 0.0005 0 0.0001 0 0.0018 0 0.0015 0 0.0011 0.0008 0.0021 0.0003
Bud Site 0.0015 0 0.0002 0 0.0005 0 0.0003 0 0.0001 0 0.0005 0 0.004 0 0.0005 0.0012 0.0024 0.0012
Cell Periphery 0.0017 0.0004 0.0011 0.0001 0.0038 0.0001 0.0005 0.0002 0.0002 0 0.0008 0 0.0008 0 0.0022 0.0002 0.0005 0.0001
Cytoplasm 0.9397 0.9962 0.9698 0.9472 0.8501 0.9919 0.8822 0.996 0.954 0.9878 0.841 0.9869 0.8641 0.9981 0.9202 0.8415 0.7555 0.8505
Cytoplasmic Foci 0.0044 0.0001 0.0017 0.0039 0.0278 0.0003 0.0031 0.0001 0.0007 0.0001 0.0021 0.0002 0.0232 0 0.0068 0.0265 0.0145 0.0174
Eisosomes 0.0004 0 0 0 0.0004 0 0.0006 0 0.0001 0 0 0 0.0005 0 0.0003 0.0004 0.0005 0.0001
Endoplasmic Reticulum 0.001 0.0002 0.0003 0.0002 0.0007 0.0002 0.0024 0 0.0084 0 0.0026 0.0001 0.0005 0 0.0017 0.0002 0.0016 0.0002
Endosome 0.0018 0 0.0001 0.0056 0.0003 0.0001 0.0023 0 0.0013 0 0.0317 0 0.0093 0 0.0031 0.0022 0.0226 0.0196
Golgi 0.0003 0 0 0.004 0.0001 0 0.0007 0 0.0001 0 0.0109 0 0.0057 0 0.0036 0.0029 0.0202 0.0269
Lipid Particles 0.0016 0 0.0003 0.0108 0.0015 0 0.0009 0 0.0004 0 0.0006 0 0.0143 0 0.0033 0.0042 0.0143 0.0248
Mitochondria 0.0044 0 0.0014 0.0028 0.0152 0.0001 0.0099 0.0001 0.0037 0.0002 0.0617 0.0001 0.0077 0 0.0055 0.0054 0.0537 0.0313
None 0.0051 0.0001 0.007 0.0003 0.0318 0.0002 0.0059 0.0002 0.0009 0.0002 0.0005 0.0003 0.0101 0.0001 0.0044 0.0331 0.0029 0.0003
Nuclear Periphery 0.0053 0.0006 0.0015 0.0025 0.004 0.0012 0.0283 0.0005 0.0105 0.0017 0.0028 0.0015 0.0029 0.0002 0.0011 0.0013 0.0036 0.0013
Nucleolus 0.0055 0 0.0037 0.0012 0.0145 0.0001 0.0057 0 0.0034 0.0001 0.0003 0 0.014 0 0.0068 0.0024 0.0018 0.0003
Nucleus 0.0112 0.0013 0.0043 0.0137 0.0161 0.0041 0.0316 0.0021 0.0104 0.0072 0.0041 0.0099 0.0098 0.0013 0.0032 0.0047 0.0114 0.0038
Peroxisomes 0.0004 0 0.0001 0.0007 0.0009 0 0.0004 0 0.0001 0 0.0003 0 0.0106 0 0.0077 0.016 0.0161 0.0147
Punctate Nuclear 0.0021 0 0.0002 0.0002 0.0019 0.0001 0.0011 0 0.0002 0 0.0001 0.0002 0.0103 0 0.0004 0.0268 0.0027 0.0007
Vacuole 0.006 0.0004 0.0054 0.0031 0.0206 0.0004 0.0057 0.0004 0.0018 0.0009 0.013 0.0001 0.0018 0 0.0006 0.0004 0.0032 0.0011
Vacuole Periphery 0.0024 0.0001 0.0011 0.0025 0.0059 0.0002 0.0065 0.0001 0.003 0.001 0.0181 0.0001 0.0009 0 0.0004 0.0001 0.0023 0.0009

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 1291.9441 1342.4195 1482.7702 1413.1398 1385.5027 1405.4823 1641.8408 1701.413 1769.1779 1573.4582
Translational Efficiency 1.4637 1.5043 1.4838 1.517 1.4478 1.4297 1.6319 1.5104 1.5821 1.5576

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1102 453 1678 380 1674 1946 1468 622 2776 2399 3146 1002

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 8928.74 16500.20 20550.00 29420.11 16460.12 17707.89 24027.07 27786.88 13470.36 17479.84 22172.49 28406.27
Standard Deviation 2615.75 4797.65 6422.83 6837.92 3490.60 4419.82 5392.97 6172.27 4862.30 4518.38 6211.57 6481.45
Intensity Change Log 2 — 0.885955 1.202610 1.720274 — 0.105417 0.545686 0.755429 — 0.430142 0.812106 1.171996

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000203 0.000078 0.000086 0.000191 0.000039 0.000038 0.000076 0.000137 0.000104 0.000046 0.000081 0.000157
Bud Neck 0.000815 0.000547 0.001149 0.001501 0.000314 0.000218 0.000959 0.001245 0.000513 0.000281 0.001060 0.001342
Bud Site 0.008725 0.002179 0.002194 0.007519 0.000984 0.000567 0.001771 0.004436 0.004057 0.000872 0.001997 0.005606
Cell Periphery 0.017162 0.012845 0.011691 0.050037 0.004122 0.003190 0.013304 0.039486 0.009299 0.005013 0.012443 0.043487
Cytoplasm 0.798940 0.834595 0.825587 0.699480 0.885679 0.911093 0.824374 0.730219 0.851246 0.896648 0.825021 0.718561
Cytoplasmic Foci 0.013819 0.008008 0.009129 0.005326 0.006211 0.004753 0.006289 0.006785 0.009231 0.005368 0.007804 0.006232
Eisosomes 0.000003 0.000002 0.000003 0.000021 0.000001 0.000001 0.000002 0.000005 0.000001 0.000001 0.000002 0.000011
Endoplasmic Reticulum 0.000329 0.000030 0.000056 0.000028 0.000045 0.000019 0.000055 0.000024 0.000157 0.000021 0.000056 0.000026
Endosome 0.000446 0.000060 0.000093 0.000050 0.000085 0.000033 0.000108 0.000048 0.000228 0.000038 0.000100 0.000049
Golgi 0.026414 0.006279 0.004215 0.001444 0.008225 0.002711 0.004078 0.002268 0.015446 0.003385 0.004151 0.001955
Lipid Particles 0.007038 0.004311 0.006463 0.021919 0.002543 0.001292 0.007659 0.014934 0.004328 0.001862 0.007021 0.017583
Mitochondria 0.000490 0.000127 0.000157 0.000114 0.000111 0.000144 0.000093 0.000116 0.000261 0.000141 0.000127 0.000115
Mitotic Spindle 0.001550 0.000376 0.000607 0.000173 0.000880 0.000384 0.000590 0.000117 0.001146 0.000383 0.000599 0.000138
None 0.006228 0.010658 0.004965 0.002255 0.005975 0.010517 0.004177 0.004029 0.006075 0.010543 0.004597 0.003356
Nuclear Periphery 0.000382 0.000363 0.000694 0.000388 0.000382 0.000159 0.000532 0.000381 0.000382 0.000197 0.000619 0.000384
Nuclear Periphery Foci 0.004263 0.003057 0.003144 0.002443 0.003817 0.001431 0.003444 0.002787 0.003994 0.001738 0.003284 0.002657
Nucleolus 0.000291 0.000081 0.000057 0.000122 0.000063 0.000069 0.000063 0.000097 0.000153 0.000071 0.000060 0.000106
Nucleus 0.041841 0.075559 0.082493 0.031565 0.052372 0.053002 0.069601 0.057099 0.048191 0.057262 0.076477 0.047416
Peroxisomes 0.000030 0.000016 0.000014 0.000042 0.000007 0.000008 0.000009 0.000025 0.000016 0.000009 0.000012 0.000031
Vacuole 0.029720 0.036664 0.044029 0.172801 0.018610 0.009217 0.059700 0.133059 0.023020 0.014400 0.051342 0.148131
Vacuole Periphery 0.041314 0.004163 0.003173 0.002581 0.009536 0.001155 0.003117 0.002702 0.022151 0.001723 0.003147 0.002656

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 4.11 3.78 0.35 -4.18 -3.84 -0.36 -4.71 -6.35 -6.00 -2.19 4.57 0.46 -3.20 -7.88 -4.20
Bud Neck 1.36 -3.20 -3.92 -5.39 -1.21 1.72 -7.47 -6.50 -6.98 -0.03 3.58 -8.29 -7.45 -9.60 -0.64
Bud Site 4.93 5.09 1.08 -4.07 -4.23 2.55 -4.30 -4.25 -4.78 -2.48 6.29 3.12 -1.68 -6.99 -4.51
Cell Periphery 1.76 2.61 -5.51 -6.32 -6.75 1.68 -8.07 -11.77 -12.11 -8.05 5.07 -3.60 -11.87 -13.84 -10.59
Cytoplasm -2.04 -0.01 6.43 7.55 6.82 -4.74 12.21 15.41 18.30 6.88 -8.20 9.21 15.41 20.71 9.81
Cytoplasmic Foci 3.64 2.18 3.24 0.69 2.02 1.53 -1.84 -0.89 -1.64 0.03 4.88 -0.25 1.42 -1.43 1.61
Eisosomes 1.03 -1.40 -1.44 -1.48 -1.37 -0.30 -7.22 -8.34 -8.15 -4.98 2.56 -6.22 -2.28 -2.40 -1.89
Endoplasmic Reticulum 8.42 7.66 8.56 0.66 5.08 4.22 -0.88 3.20 -1.51 2.88 9.28 6.45 8.97 -1.29 5.30
Endosome 7.93 7.02 8.17 1.22 5.27 3.98 -2.17 2.42 -2.21 4.73 9.01 5.13 8.34 -2.07 6.74
Golgi 9.56 11.26 12.79 5.45 8.95 8.42 6.12 9.39 1.39 3.79 13.19 12.70 15.38 4.04 7.23
Lipid Particles 2.09 0.00 -5.07 -6.21 -5.34 3.22 -8.49 -7.63 -8.44 -4.05 4.91 -5.59 -8.88 -10.90 -6.74
Mitochondria 5.71 5.14 2.71 -0.20 0.25 -1.19 0.25 -0.39 0.69 -0.48 1.97 4.41 2.24 0.43 0.18
Mitotic Spindle 4.98 3.29 6.71 0.79 3.96 1.57 0.33 2.62 2.04 1.64 3.56 1.44 5.20 1.99 3.26
None -2.04 1.37 4.14 4.86 7.42 -5.25 4.50 3.95 7.55 0.46 -5.23 3.49 5.63 9.58 3.85
Nuclear Periphery -0.02 -5.53 -0.52 -0.46 4.35 5.65 -3.52 -0.19 -6.46 3.49 5.91 -6.42 -0.49 -5.79 5.85
Nuclear Periphery Foci 2.04 1.89 4.18 1.35 2.60 5.58 0.32 2.10 -2.77 2.07 6.97 1.40 3.66 -2.70 2.81
Nucleolus 1.30 1.43 1.08 -1.87 -3.26 -0.72 -0.49 -1.70 0.10 -2.24 0.81 1.36 0.81 -0.19 -4.01
Nucleus -6.16 -12.83 1.31 6.78 12.95 -0.30 -7.55 -1.78 -1.59 4.53 -3.76 -14.46 -0.83 2.34 11.44
Peroxisomes 1.86 2.25 -1.12 -3.13 -3.57 -0.75 -1.42 -3.47 -3.11 -2.84 2.25 1.24 -3.10 -5.17 -3.97
Vacuole -2.13 -5.22 -12.93 -11.03 -10.95 4.61 -12.89 -15.80 -17.28 -8.26 4.04 -13.34 -20.32 -21.59 -13.96
Vacuole Periphery 9.99 10.47 10.68 1.70 1.72 6.79 5.07 5.63 -3.94 1.69 12.35 11.44 11.88 -2.32 2.41
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Glycolytic enzyme phosphoglucose isomerase; catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate; required for cell cycle progression and completion of the gluconeogenic events of sporulation
Localization
Cell Percentages cytoplasm (99%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-1

Pgi1

Pgi1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pgi1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available