Standard name
Human Ortholog
Description Putative transporter, member of the sugar porter family; green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane; YBR241C is not an essential gene; YBR241C has a paralog, VPS73, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Cytoplasm 0.06 0.13 0.12 0.43 0.5 0.46 0.36 0.42 0.45 0.47 0.54 0.46 0.18 0.24 0.11 0.25 – – 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0.11 0.06 0.08 0.08 0.1 0.08 0.05 0.05 0.05 0 0 0 0.12 – – 0 0 0 0 0 0
Endosome 0.08 0 0.17 0.11 0.09 0 0 0 0 0 0 0 0 0.06 0.05 0 – – 0.08 0 0.12 0.05 0.08 0.1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Mitochondria 0 0 0 0.06 0 0.11 0.17 0.13 0.27 0.27 0.27 0.25 0 0 0 0 – – 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0.06 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Vac/Vac Membrane 0.91 0.87 0.82 0.39 0.49 0.41 0.45 0.39 0.29 0.3 0.26 0.33 0.81 0.79 0.91 0.67 – – 0.83 0.86 0.77 0.83 0.81 0.8
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 1 1 0 3 10 3 8 2 2 2 1 0 0 – – 0 0 0 0 1 0
Bud 0 0 0 0 0 0 5 1 4 2 3 4 0 1 0 0 – – 0 1 3 2 1 2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – – –
Cell Periphery 0 0 0 0 1 1 4 11 16 14 10 11 0 0 0 0 – – 0 0 0 0 0 0
Cytoplasm 7 38 51 99 182 223 240 325 196 205 267 223 33 30 17 6 – – 0 6 1 1 1 3
Endoplasmic Reticulum 2 3 6 26 22 39 53 76 37 20 23 22 4 2 3 3 – – 0 1 3 0 2 1
Endosome 10 5 73 25 31 18 27 21 7 6 3 10 4 8 8 0 – – 11 13 54 7 21 23
Golgi 1 1 4 4 7 12 28 29 8 5 5 9 0 2 2 1 – – 0 2 2 0 1 0
Mitochondria 4 7 13 13 6 51 111 102 118 116 134 122 0 0 0 1 – – 3 3 4 1 2 3
Nucleus 2 10 5 1 2 5 5 7 3 2 5 0 9 5 4 0 – – 2 3 2 5 5 7
Nuclear Periphery 3 4 8 3 1 2 8 27 9 4 2 5 3 0 2 0 – – 3 1 26 5 6 4
Nucleolus 3 2 13 1 0 1 4 3 1 3 1 1 0 1 1 0 – – 0 1 1 1 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
SpindlePole 0 0 4 0 0 0 0 0 0 0 1 0 0 0 0 0 – – 0 0 1 0 0 1
Vac/Vac Membrane 108 250 354 91 177 200 298 306 127 131 131 163 149 100 144 16 – – 111 264 354 130 208 192
Unique Cell Count 119 289 434 231 362 484 669 781 437 434 499 487 184 127 159 24 135 307 460 156 257 242
Labelled Cell Count 140 320 531 264 430 552 786 918 529 516 587 572 204 150 181 27 135 307 460 156 257 242


Vacuole Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.9 8.7 7.7 7.8 9.3 8.9 9.2 10.0 9.4 9.4 9.5 10.1 9.1 10.1 11.3 10.0 – – 7.8 9.1 10.0
Std Deviation (1e-4) 1.7 1.8 1.7 1.8 2.3 2.3 2.3 2.6 2.8 2.9 3.0 3.3 2.3 2.5 3.3 3.0 – – 1.7 1.9 2.3
Intensity Change (Log2) – – – 0.01 0.26 0.21 0.25 0.37 0.28 0.28 0.29 0.38 0.23 0.38 0.54 0.36 – – 0.0 0.23 0.37


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Cell Periphery 0 0 0 0 0 4.0 3.8 0 3.1 0 0 0 0 – –
Cytoplasm 9.1 11.9 11.3 8.9 10.8 10.8 11.5 13.4 11.3 2.1 3.3 -0.4 0 – –
Endoplasmic Reticulum 5.7 3.6 4.7 4.7 5.6 4.8 2.8 2.8 2.8 0 0 0 0 – –
Endosome -2.1 -3.4 -6.6 -7.2 -8.8 -7.8 -7.9 -9.0 -7.8 -5.0 -3.0 -3.7 0 – –
Golgi 0 1.2 1.8 3.2 2.9 1.2 0 0 1.2 0 0 0 0 – –
Mitochondria 1.7 -1.2 4.5 7.0 5.7 9.9 9.8 10.0 9.4 0 0 0 0 – –
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Nuclear Periphery 0 0 0 -0.9 1.6 0.2 -1.2 0 -1.0 0 0 0 0 – –
Nucleolus 0 -3.3 -3.4 -3.2 -3.8 -3.2 -2.5 -3.5 -3.5 0 0 0 0 – –
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Vacuole -11.0 -9.7 -12.4 -12.2 -14.2 -15.6 -15.2 -16.9 -14.7 -0.2 -0.7 2.6 -1.8 – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.0057 0 0.0012 0.0383 0.0001 0.0012 0.0081 0 0.0047 0 0 0.0001 – – – – – –
Bud 0.0005 0.0008 0.0033 0.0006 0.0004 0.0017 0.0008 0.0029 0.001 0.0002 0.0004 0.0003 – – – – – –
Bud Neck 0.0038 0.0005 0.0008 0.0006 0.0004 0.0012 0.001 0.0007 0.0021 0.0004 0.0003 0.0006 – – – – – –
Bud Periphery 0.001 0.0011 0.0075 0.0007 0.0006 0.0027 0.0018 0.0037 0.0019 0.0003 0.0008 0.0006 – – – – – –
Bud Site 0.0014 0.0024 0.0044 0.0018 0.0002 0.0011 0.0027 0.0061 0.0027 0.0009 0.0005 0.0005 – – – – – –
Cell Periphery 0.0007 0.0008 0.0049 0.0003 0.0006 0.0005 0.0011 0.0008 0.0012 0.0004 0.0005 0.0007 – – – – – –
Cytoplasm 0.021 0.0435 0.0325 0.0219 0.0139 0.0292 0.0192 0.0175 0.0209 0.006 0.0178 0.019 – – – – – –
Cytoplasmic Foci 0.0127 0.0066 0.0085 0.0099 0.007 0.0068 0.012 0.0083 0.0163 0.0109 0.0087 0.0088 – – – – – –
Eisosomes 0.0001 0 0.0001 0.0002 0 0 0.0008 0 0 0 0 0 – – – – – –
Endoplasmic Reticulum 0.0065 0.0052 0.0056 0.0026 0.0016 0.0049 0.0055 0.0097 0.0043 0.001 0.0023 0.0032 – – – – – –
Endosome 0.1943 0.1378 0.1646 0.1106 0.1926 0.1563 0.2153 0.1456 0.249 0.3025 0.2013 0.2123 – – – – – –
Golgi 0.01 0.0019 0.0024 0.0114 0.0032 0.0043 0.0077 0.0022 0.0083 0.0041 0.0081 0.0039 – – – – – –
Lipid Particles 0.0091 0.0009 0.0036 0.0092 0.0013 0.0052 0.0093 0.0018 0.0037 0.0037 0.0054 0.0039 – – – – – –
Mitochondria 0.0116 0.0025 0.0062 0.0022 0.0042 0.0052 0.0182 0.0048 0.0117 0.0024 0.0061 0.0106 – – – – – –
None 0.0127 0.0025 0.0121 0.0136 0.0004 0.0009 0.0152 0.0026 0.0088 0.0005 0.0401 0.0126 – – – – – –
Nuclear Periphery 0.0245 0.0155 0.012 0.011 0.0059 0.0141 0.0097 0.0127 0.0139 0.0038 0.004 0.0185 – – – – – –
Nucleolus 0.0031 0.0017 0.0019 0.0011 0.0006 0.0015 0.002 0.0018 0.0033 0.0016 0.0007 0.0013 – – – – – –
Nucleus 0.0105 0.0136 0.0056 0.0036 0.0019 0.0135 0.0107 0.0046 0.01 0.0018 0.0027 0.0043 – – – – – –
Peroxisomes 0.0068 0.0001 0.0005 0.0048 0.0002 0.0061 0.0088 0.0006 0.0019 0.0005 0.0003 0.0004 – – – – – –
Punctate Nuclear 0.0028 0.0002 0.0002 0.0052 0.0002 0.001 0.0009 0.0002 0.0007 0.0002 0.0004 0.0002 – – – – – –
Vacuole 0.4708 0.5879 0.5252 0.5727 0.506 0.4983 0.4399 0.5305 0.4265 0.4786 0.3914 0.4089 – – – – – –
Vacuole Periphery 0.1905 0.1747 0.1969 0.1775 0.2588 0.2442 0.2093 0.2429 0.207 0.1802 0.3081 0.2891 – – – – – –

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 29.3339 18.8265 9.9786 8.1089 8.7768 20.2968 19.8853 13.0771 15.6881 18.0346
Translational Efficiency 0.5224 0.398 0.5743 0.8315 1.2283 0.9191 0.6416 0.8488 0.7656 0.7148

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
155 1555 279 1142 1664 2178 2740 1863 1819 3733 3019 3005

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 954.16 1038.85 1339.24 1031.52 790.11 977.14 958.51 990.74 804.09 1002.85 993.70 1006.24
Standard Deviation 166.62 200.90 282.55 200.82 114.22 152.74 145.68 156.93 128.06 177.06 196.97 176.03
Intensity Change Log 2 — 0.122684 0.489111 0.112469 — 0.306512 0.278740 0.326453 — 0.208865 0.397598 0.213345

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000379 0.000028 0.000130 0.000092 0.000027 0.000017 0.000015 0.000043 0.000057 0.000021 0.000025 0.000061
Bud Neck 0.005961 0.001065 0.010320 0.005816 0.002848 0.001263 0.005086 0.004685 0.003113 0.001181 0.005570 0.005115
Bud Site 0.008770 0.004678 0.005229 0.025190 0.009182 0.001907 0.010341 0.017187 0.009147 0.003061 0.009869 0.020228
Cell Periphery 0.000079 0.000112 0.000314 0.000132 0.000161 0.000124 0.000068 0.000156 0.000154 0.000119 0.000090 0.000147
Cytoplasm 0.030765 0.009998 0.003073 0.049016 0.043547 0.002209 0.040873 0.037658 0.042458 0.005454 0.037380 0.041974
Cytoplasmic Foci 0.019117 0.011181 0.005174 0.018415 0.035597 0.004986 0.008072 0.014938 0.034193 0.007567 0.007804 0.016259
Eisosomes 0.000020 0.000003 0.000049 0.000008 0.000012 0.000005 0.000005 0.000007 0.000013 0.000005 0.000009 0.000007
Endoplasmic Reticulum 0.002541 0.001805 0.002562 0.002347 0.008678 0.003143 0.001091 0.001859 0.008156 0.002586 0.001227 0.002045
Endosome 0.114840 0.037150 0.030548 0.051469 0.063217 0.034299 0.031978 0.065440 0.067616 0.035486 0.031846 0.060131
Golgi 0.010990 0.006158 0.003673 0.007531 0.002321 0.002980 0.003303 0.005523 0.003060 0.004304 0.003337 0.006286
Lipid Particles 0.001740 0.000405 0.002099 0.000680 0.002134 0.000593 0.000233 0.000672 0.002100 0.000515 0.000406 0.000675
Mitochondria 0.003803 0.001719 0.001394 0.002313 0.004119 0.003712 0.001774 0.002847 0.004092 0.002882 0.001739 0.002644
Mitotic Spindle 0.005022 0.001987 0.001443 0.009825 0.000704 0.000776 0.002281 0.003996 0.001072 0.001281 0.002203 0.006211
None 0.000073 0.000451 0.000263 0.000344 0.000371 0.000165 0.000273 0.000280 0.000345 0.000284 0.000272 0.000304
Nuclear Periphery 0.002882 0.000994 0.004909 0.001584 0.000288 0.001321 0.000869 0.001533 0.000509 0.001185 0.001243 0.001552
Nuclear Periphery Foci 0.004051 0.001054 0.006826 0.002116 0.000375 0.001114 0.000396 0.000753 0.000688 0.001089 0.000990 0.001271
Nucleolus 0.002162 0.000686 0.015514 0.001534 0.000594 0.001609 0.001888 0.001210 0.000727 0.001225 0.003147 0.001333
Nucleus 0.016908 0.001581 0.036165 0.006084 0.002727 0.002802 0.008962 0.004734 0.003936 0.002294 0.011476 0.005247
Peroxisomes 0.001657 0.000282 0.002373 0.000983 0.000376 0.000407 0.000382 0.000648 0.000485 0.000355 0.000566 0.000775
Vacuole 0.651816* 0.367539* 0.429996* 0.624526* 0.569515* 0.494518* 0.630349* 0.632263* 0.576528* 0.441624* 0.611833* 0.629323*
Vacuole Periphery 0.116424* 0.551124* 0.437946* 0.189993* 0.253207* 0.442048* 0.251763* 0.203569* 0.241551* 0.487484* 0.268969* 0.198409*

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.57 1.14 1.22 -3.03 0.56 1.66 1.94 -2.35 -4.28 -4.81 1.77 1.50 -0.45 -4.31 -3.79
Bud Neck 4.37 -2.14 -0.15 -6.96 2.24 3.19 -4.63 -3.56 -7.23 0.91 4.51 -5.12 -4.30 -10.10 0.94
Bud Site 1.96 1.57 -4.98 -7.96 -7.35 7.00 -1.30 -4.82 -10.90 -4.39 6.09 -0.96 -7.14 -13.05 -7.27
Cell Periphery -1.21 -2.57 -2.07 -0.89 2.05 1.89 6.23 0.12 -0.89 -2.57 2.18 3.95 0.30 -1.15 -2.33
Cytoplasm 2.48 3.10 -2.82 -11.30 -12.42 15.20 -0.57 -0.14 -14.67 0.41 14.04 0.24 -2.24 -18.18 -2.66
Cytoplasmic Foci 2.53 4.30 0.33 -4.02 -7.02 15.97 14.59 9.99 -9.11 -6.64 14.96 15.07 9.62 -9.02 -9.32
Eisosomes 4.06 -2.66 3.04 -7.40 4.31 3.21 3.63 2.30 -2.66 -5.28 4.32 1.98 2.81 -5.81 1.28
Endoplasmic Reticulum 0.92 -0.05 0.35 -1.08 0.69 7.98 11.48 9.99 4.42 -3.60 8.86 11.33 9.70 2.28 -3.86
Endosome 6.73 6.86 5.64 -3.53 -3.48 9.20 12.13 -0.33 -9.38 -12.23 11.18 13.74 2.97 -9.69 -12.97
Golgi 1.21 1.85 0.95 -0.95 -3.30 -1.23 -3.34 -5.63 -3.39 -3.93 -2.26 -0.58 -5.27 -2.96 -5.89
Lipid Particles 1.79 -0.33 1.37 -3.05 2.54 4.82 6.12 3.98 -0.79 -2.94 5.40 5.71 4.43 -1.84 -2.57
Mitochondria 1.28 1.48 0.86 -0.56 -0.92 0.55 4.39 1.97 1.32 -2.22 2.05 4.64 2.36 0.54 -1.85
Mitotic Spindle 1.38 1.58 -1.73 -4.12 -4.35 -0.17 -2.81 -4.01 -4.26 -2.01 -0.35 -2.08 -5.51 -5.68 -4.29
None -2.20 -2.28 -3.03 0.44 -0.68 1.59 0.69 0.57 -1.81 -0.12 0.44 0.54 0.21 -0.38 -0.64
Nuclear Periphery 1.16 -1.20 0.75 -1.65 4.25 -6.06 -4.57 -2.69 -0.46 -1.15 -3.55 -4.08 -3.06 -1.18 -0.64
Nuclear Periphery Foci 1.18 -1.00 0.68 -2.23 2.47 -1.56 -0.39 -2.04 0.69 -2.11 -1.07 -1.20 -2.01 -0.76 -1.01
Nucleolus 2.25 -5.26 0.81 -2.89 5.62 -3.51 -6.27 -2.82 1.35 3.59 -2.24 -7.89 -2.97 -0.70 6.10
Nucleus 3.25 -2.27 1.93 -6.82 3.88 -0.10 -7.45 -2.86 -3.33 4.90 2.19 -7.06 -2.58 -6.89 5.72
Peroxisomes 2.87 -1.06 1.32 -2.75 2.60 -0.31 -0.17 -3.05 -2.35 -2.51 1.56 -0.85 -2.32 -3.67 -1.45
Vacuole 13.62 8.52 1.36 -26.86 -10.63 9.19 -7.97 -7.51 -17.66 -0.23 18.83 -4.72 -6.97 -30.70 -2.65
Vacuole Periphery -29.43* -13.38 -4.44 39.63* 12.20 -23.77* 1.04 7.53 32.37* 7.32 -35.52 -3.16 7.84 49.88* 12.29
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative transporter, member of the sugar porter family; green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane; YBR241C is not an essential gene; YBR241C has a paralog, VPS73, that arose from the whole genome duplication
Localization
Cell Percentages vacuolar membrane (60%)
Cell Cycle Regulation No
Subcompartmental Group vac memb-1

Vvs1

Vvs1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Vvs1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available