Standard name
Human Ortholog
Description Cytoplasmic RNA-binding protein; shuttles between nucleus and cytoplasm and is exported from the nucleus in an mRNA export-dependent manner; associates with translating ribosomes; involved in heme regulation of Hap1p as a component of the HMC complex, also involved in the organization of actin filaments; contains a La motif; SRO9 has a paralog, SLF1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 0.98 0.97 0.98 0.97 0.94 0.92 0.82 0.82 0.75 0.72 0.75 0.96 1.0 0.99 0.93 1.0 0.99 0.93 0.95 0.81 0.93 0.95 0.83
Endoplasmic Reticulum 0 0 0 0 0 0 0.05 0.07 0.07 0.1 0.11 0.07 0 0 0 0 0.07 0.08 0 0 0.08 0 0 0.09
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0.09 0.13 0.13 0.15 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0.05 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 1 2 7 5 3 3 8 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 1 0 0 3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 0 0 0 6 4 8 10 3 9 6 20 0 6 2 11 7 6 0 0 0 0 0 0
Cytoplasm 101 188 130 165 204 208 261 216 111 158 123 159 94 238 218 315 208 206 91 178 106 89 149 162
Endoplasmic Reticulum 1 4 3 3 4 7 13 19 9 20 19 15 4 1 2 14 15 16 0 2 10 2 4 17
Endosome 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 2 4 3 1 4 0 0 0 0 5 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 1 4 5 12 27 23 32 0 0 0 9 1 1 0 0 1 0 0 1
Nucleus 0 0 0 0 0 0 1 0 1 1 0 0 0 0 0 1 0 0 1 1 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 1 1 1 4 7 14 3 9 11 3 0 1 0 5 0 2 0 1 3 1 0 6
Unique Cell Count 102 191 134 169 211 221 285 264 136 210 172 213 98 239 220 337 209 208 99 189 131 96 158 197
Labelled Cell Count 104 192 134 169 215 225 298 275 147 228 191 238 98 246 222 365 231 231 99 189 131 96 158 197


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 66.0 84.4 57.4 59.9 46.2 32.1 26.7 25.3 20.9 18.6 17.5 16.5 70.4 66.8 60.6 69.0 90.4 106.3 65.1 69.8 75.3
Std Deviation (1e-4) 18.3 19.0 18.2 14.0 10.0 8.0 6.0 5.9 5.5 4.8 4.6 3.6 20.2 13.9 15.2 26.2 29.4 28.4 23.1 16.7 20.4
Intensity Change (Log2) – – – 0.06 -0.31 -0.84 -1.1 -1.18 -1.46 -1.63 -1.71 -1.8 0.29 0.22 0.08 0.27 0.66 0.89 0.18 0.28 0.39

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700050100WT3HU80HU120HU160050100WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3050100WT1AF100AF140AF180050100
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 3.7 0 0 0 0 0 0
Cytoplasm 0.3 -0.2 -1.2 -2.1 -4.3 -4.1 -5.3 -5.8 -5.4 -0.5 2.1 1.5 -1.5 1.9 1.4
Endoplasmic Reticulum 0 0 0 1.2 2.0 1.7 2.6 3.0 2.0 0 0 0 0 2.0 2.1
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 3.5 4.3 4.4 4.7 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 2.3 0 0 2.5 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 49.0289 73.1651 62.2989 52.5297 66.0472 58.5268 54.1717 70.8643 64.1647 57.485 52.8161 65.1723 59.9468 78.637 70.0496 71.616 59.0514 70.6933
Actin 0.0017 0.0004 0.0045 0.0001 0.0001 0.0004 0.0207 0.0004 0.0109 0.0005 0.004 0.0009 0.0049 0.0005 0.0237 0.0005 0.0016 0.0029
Bud 0.001 0.0007 0.0012 0.0008 0.0003 0.0009 0.001 0.0008 0.0017 0.0007 0.0015 0.0013 0.001 0.0003 0.0009 0.001 0.0132 0.0014
Bud Neck 0.0006 0.0008 0.0007 0.0006 0.0008 0.0007 0.0006 0.0002 0.0004 0.0005 0.0049 0.0008 0.0006 0.0003 0.0006 0.0008 0.0004 0.001
Bud Periphery 0.001 0.0007 0.0009 0.0003 0.0001 0.0006 0.0011 0.0005 0.0007 0.0003 0.0009 0.0008 0.0007 0.0001 0.0004 0.0005 0.0048 0.0004
Bud Site 0.0008 0.0004 0.001 0.0001 0 0.0002 0.0021 0.0005 0.0037 0.0037 0.0495 0.0002 0.0006 0.0008 0.0015 0.0004 0.0025 0.0001
Cell Periphery 0.008 0.0036 0.0052 0.001 0.0005 0.0005 0.0033 0.0012 0.0005 0.0003 0.0006 0.0001 0.0039 0.0013 0.0004 0.0016 0.0009 0.0001
Cytoplasm 0.696 0.8814 0.7936 0.7187 0.8712 0.6431 0.8056 0.9735 0.9158 0.8015 0.7308 0.9114 0.8161 0.9774 0.895 0.9313 0.8351 0.9462
Cytoplasmic Foci 0.0184 0.0011 0.0037 0.0021 0.0019 0.0089 0.0143 0.0017 0.0096 0.0195 0.0267 0.0049 0.0144 0.0009 0.0153 0.0036 0.017 0.0049
Eisosomes 0.0001 0 0 0 0 0.0001 0.0024 0 0.0002 0 0 0 0.0001 0.0001 0.0002 0 0.0003 0
Endoplasmic Reticulum 0.0828 0.0325 0.0256 0.0045 0.0346 0.0798 0.0537 0.0112 0.0035 0.028 0.0042 0.028 0.0342 0.0018 0.0025 0.0025 0.0085 0.0077
Endosome 0.0178 0.0048 0.0091 0.0121 0.0117 0.0293 0.0129 0.0015 0.0131 0.0272 0.0544 0.0228 0.0185 0.0009 0.0088 0.0068 0.0171 0.0136
Golgi 0.003 0.0004 0.0009 0.0001 0.0002 0.0014 0.0052 0.0003 0.005 0.0029 0.006 0.0045 0.0032 0.0003 0.0116 0.0003 0.0018 0.0012
Lipid Particles 0.0117 0.0002 0.003 0.0003 0.0001 0.0069 0.0065 0.0002 0.001 0.0037 0.0054 0.0006 0.0057 0.0002 0.0019 0.001 0.0122 0
Mitochondria 0.0047 0.0006 0.0031 0.0002 0.0002 0.0086 0.0179 0.0003 0.007 0.0784 0.063 0.0024 0.0049 0.0005 0.0034 0.0003 0.0333 0.0013
None 0.0036 0.0002 0.0007 0.0003 0.0001 0.0039 0.0035 0.0014 0.0011 0.0012 0.0012 0.0005 0.0043 0.0002 0.0044 0.0002 0.0144 0.0004
Nuclear Periphery 0.022 0.0068 0.0088 0.0085 0.0036 0.0139 0.013 0.0006 0.0013 0.0019 0.0021 0.0035 0.0225 0.0012 0.0018 0.0038 0.0046 0.0071
Nucleolus 0.0034 0.0001 0.0004 0.0004 0 0.006 0.0003 0.0001 0.0012 0.0011 0.0005 0 0.0011 0.0037 0.0006 0.0001 0.0013 0
Nucleus 0.0057 0.0033 0.0036 0.0058 0.0026 0.005 0.0033 0.0007 0.0016 0.0024 0.0022 0.0023 0.0104 0.0022 0.0016 0.0037 0.0051 0.0052
Peroxisomes 0.003 0 0.0043 0 0 0.0014 0.0018 0 0.0007 0.0007 0.0007 0.0001 0.0014 0 0.0034 0.0001 0.0018 0.0001
Punctate Nuclear 0.0047 0 0.0001 0.0001 0 0.005 0.0033 0 0.0002 0.001 0.0005 0.0002 0.0036 0.0001 0.0003 0.0001 0.0007 0.0001
Vacuole 0.0888 0.0551 0.1101 0.1907 0.0512 0.1297 0.0206 0.0044 0.0159 0.02 0.0272 0.0102 0.0405 0.0062 0.0178 0.0341 0.0167 0.0038
Vacuole Periphery 0.0211 0.0069 0.0194 0.053 0.0208 0.0536 0.0069 0.0007 0.005 0.0043 0.0136 0.0048 0.0074 0.0008 0.004 0.0072 0.0068 0.0024

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 178.4049 218.4389 181.7215 171.1437 190.7483 145.349 159.5336 125.3408 118.7377 158.8158
Translational Efficiency 2.5771 1.9911 1.7842 1.1822 1.7322 2.2798 1.5463 1.6651 1.5888 1.7006

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1563 1180 2117 354 2324 1561 2467 365 3887 2741 4584 719

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 4042.06 4494.01 5840.22 5801.91 4163.23 4279.52 6377.69 6233.11 4114.51 4371.86 6129.47 6020.81
Standard Deviation 749.72 1039.43 1331.20 1451.16 805.52 914.94 1130.67 1457.94 785.81 976.29 1256.27 1470.49
Intensity Change Log 2 — 0.152913 0.530932 0.521437 — 0.039746 0.615331 0.582249 — 0.096603 0.574371 0.552612

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000046 0.000090 0.000079 0.000414 0.000024 0.000081 0.000056 0.000164 0.000033 0.000085 0.000067 0.000287
Bud Neck 0.000277 0.000648 0.000861 0.003780 0.000090 0.000371 0.000547 0.001883 0.000165 0.000490 0.000692 0.002817
Bud Site 0.001956 0.004177 0.003414 0.021354 0.001822 0.004043 0.003216 0.008427 0.001876 0.004100 0.003308 0.014792
Cell Periphery 0.005009 0.015861 0.015479 0.040417 0.005467 0.007765 0.008216 0.057245 0.005283 0.011250 0.011570 0.048960
Cytoplasm 0.716531 0.667681 0.617578 0.629225 0.775337 0.746127 0.702985 0.631883 0.751691 0.712356 0.663542 0.630574
Cytoplasmic Foci 0.013217 0.012974 0.007770 0.006988 0.015294 0.011975 0.004492 0.006237 0.014459 0.012405 0.006006 0.006607
Eisosomes 0.000001 0.000002 0.000002 0.000007 0.000001 0.000001 0.000001 0.000004 0.000001 0.000001 0.000001 0.000006
Endoplasmic Reticulum 0.000624 0.001135 0.001083 0.000137 0.001305 0.000771 0.000483 0.000161 0.001031 0.000928 0.000760 0.000149
Endosome 0.000844 0.001152 0.000737 0.000487 0.000623 0.000862 0.000513 0.001723 0.000711 0.000987 0.000616 0.001114
Golgi 0.090682 0.088427 0.047816 0.009369 0.059937 0.074071 0.018544 0.008629 0.072300 0.080251 0.032063 0.008993
Lipid Particles 0.005859 0.014497 0.009295 0.024225 0.005507 0.006411 0.007909 0.014869 0.005649 0.009892 0.008549 0.019475
Mitochondria 0.000124 0.000206 0.000250 0.000330 0.000256 0.000250 0.000219 0.000649 0.000203 0.000231 0.000233 0.000492
Mitotic Spindle 0.001146 0.001075 0.001453 0.000944 0.000722 0.001522 0.000615 0.001098 0.000892 0.001330 0.001002 0.001022
None 0.001722 0.001884 0.001084 0.004457 0.001173 0.001971 0.000612 0.002667 0.001394 0.001934 0.000830 0.003548
Nuclear Periphery 0.000418 0.000578 0.000940 0.000355 0.000259 0.000358 0.000291 0.000321 0.000323 0.000453 0.000591 0.000338
Nuclear Periphery Foci 0.012846 0.015476 0.010234 0.003210 0.008444 0.010057 0.004658 0.002796 0.010214 0.012390 0.007233 0.003000
Nucleolus 0.000053 0.000088 0.000097 0.000318 0.000031 0.000075 0.000117 0.000201 0.000040 0.000081 0.000108 0.000258
Nucleus 0.005246 0.005699 0.007063 0.079968 0.001758 0.004286 0.006882 0.069772 0.003161 0.004894 0.006965 0.074792
Peroxisomes 0.000008 0.000033 0.000036 0.000092 0.000019 0.000472 0.000045 0.002110 0.000015 0.000283 0.000041 0.001116
Vacuole 0.043619 0.091773 0.162412 0.162473 0.035061 0.056833 0.176601 0.174711 0.038502 0.071875 0.170048 0.168686
Vacuole Periphery 0.099774 0.076544 0.112316 0.011450 0.086870 0.071700 0.062999 0.014451 0.092059 0.073785 0.085774 0.012973

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.91 -5.41 -8.07 -7.04 -7.04 -5.71 -6.79 -7.90 -5.24 -5.76 -7.63 -9.09 -10.96 -8.68 -8.95
Bud Neck -4.40 -8.20 -9.47 -8.81 -8.28 -6.35 -8.07 -9.38 -8.57 -7.27 -7.38 -11.73 -12.94 -11.97 -10.81
Bud Site -5.24 -4.80 -4.55 -3.78 -3.99 -5.30 -6.34 -7.19 -3.72 -4.47 -7.42 -8.05 -6.23 -4.66 -5.01
Cell Periphery -9.74 -11.60 -5.78 -2.15 -2.33 -3.14 -3.99 -5.12 -4.63 -4.60 -9.24 -11.19 -7.34 -5.24 -5.21
Cytoplasm 4.00 9.69 9.12 6.06 3.26 3.24 9.65 11.75 9.56 6.89 5.33 14.26 15.25 11.42 7.38
Cytoplasmic Foci 0.14 5.29 -0.90 -0.95 -3.89 2.79 10.91 0.33 -1.39 -5.68 2.22 11.65 -0.24 -1.71 -6.89
Eisosomes -6.32 -6.55 -7.86 -7.05 -6.69 -3.98 -6.34 -7.28 -6.13 -6.20 -6.70 -9.24 -10.59 -9.27 -9.02
Endoplasmic Reticulum -3.64 -3.49 9.21 7.89 8.33 2.54 6.64 9.64 3.72 6.76 0.78 3.10 11.95 7.09 10.53
Endosome -2.85 1.11 5.43 7.84 5.93 -2.98 2.02 -0.44 -0.10 -0.54 -4.26 1.76 0.16 0.89 -0.02
Golgi 0.53 11.96 24.17 22.03 22.16 -3.84 18.49 24.02 22.46 11.76 -2.63 20.04 33.59 31.29 24.21
Lipid Particles -6.79 -5.35 -4.13 -1.07 -2.87 -1.69 -3.68 -3.17 -2.55 -1.50 -6.65 -6.33 -5.18 -2.47 -3.25
Mitochondria -2.75 -5.59 -3.27 -2.18 -1.43 -0.07 0.51 -1.03 -1.01 -1.13 -0.95 -1.65 -1.89 -1.62 -1.54
Mitotic Spindle 0.38 -1.47 -1.38 -1.51 -0.51 -3.86 -0.41 -1.59 -0.38 -1.42 -3.21 -1.61 -2.20 -1.21 -1.43
None -0.86 4.20 -4.11 -3.87 -5.11 -2.22 9.02 -5.07 -2.65 -6.17 -2.46 7.80 -6.45 -4.53 -7.81
Nuclear Periphery -2.23 -7.30 -4.39 -3.24 0.10 -1.73 -3.03 -5.95 -3.70 -4.89 -2.94 -8.58 -7.17 -4.96 -2.80
Nuclear Periphery Foci -2.36 2.45 11.05 13.17 13.20 -2.00 6.96 11.23 9.57 5.86 -3.28 5.54 15.47 15.75 13.70
Nucleolus -3.08 -5.41 -4.51 -3.87 -3.68 -4.07 -10.61 -9.64 -6.24 -4.37 -5.23 -12.24 -7.41 -5.87 -4.94
Nucleus -0.81 -3.56 -14.03 -13.98 -13.72 -3.81 -10.69 -13.50 -13.26 -12.70 -3.43 -10.62 -19.51 -19.27 -18.67
Peroxisomes -4.94 -4.98 -5.94 -3.21 -2.88 -1.01 -5.58 -1.04 -0.50 -1.02 -1.04 -7.25 -1.09 -0.47 -1.05
Vacuole -10.02 -25.07 -10.90 -6.11 0.30 -7.21 -31.18 -11.45 -9.23 1.60 -12.33 -40.26 -15.94 -11.17 1.42
Vacuole Periphery 4.49 -2.09 21.99 20.01 32.07 3.60 7.55 24.55 18.92 20.73 5.60 3.02 33.09 27.34 37.16
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Cytoplasmic RNA-binding protein; shuttles between nucleus and cytoplasm and is exported from the nucleus in an mRNA export-dependent manner; associates with translating ribosomes; involved in heme regulation of Hap1p as a component of the HMC complex, also involved in the organization of actin filaments; contains a La motif; SRO9 has a paralog, SLF1, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-2

Sro9

Sro9


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sro9-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available