Standard name
Human Ortholog
Description Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA; relocalizes to the cytosol in response to hypoxia
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0.06 0 0.05 0.05 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0.07 0.07 0.05 0 0 0.05 0 0 0 0 0.06 0.07 0.14 0 0.08 0.11 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.33 0 0 0 0.09 0.13 0.09 0.37 0.3 0.34 0.36 0 0 0 0.11 0.09 0 0 0 0 0 0 0
Nucleus 0.97 0.93 0.87 0.9 0.92 0.89 0.89 0.9 0.79 0.84 0.84 0.84 0.94 0.93 0.84 0.89 0.82 0.88 0.89 0.88 0.77 0.92 0.83 0.75
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0.06 0 0 0 0 0 0 0.14 0.12 0.12 0.13 0.12 0 0 0 0 0 0 0 0.06 0 0 0.09
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0.05 0 0 0 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0
Bud 0 0 0 0 0 0 1 1 2 4 2 5 0 0 0 2 0 0 1 1 0 0 0 0
Bud Neck 0 0 0 0 0 0 1 1 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0
Bud Site 0 0 0 1 1 2 6 3 15 11 18 24 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 4 1 16 17 17 12 16 19 10 8 8 8 1 10 19 4 8 7 1 0 7 0 2 2
Endoplasmic Reticulum 0 0 0 0 0 1 0 0 2 1 0 1 0 0 0 2 3 0 0 0 0 0 0 1
Endosome 0 0 6 2 2 2 3 1 1 0 1 0 0 0 1 1 0 0 1 1 3 0 1 2
Golgi 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 1
Mitochondria 4 60 4 5 3 25 49 36 98 90 125 181 0 3 0 14 9 0 0 1 5 0 2 1
Nucleus 196 169 203 210 291 258 343 348 209 256 308 424 15 138 117 111 80 57 184 168 187 36 102 116
Nuclear Periphery 0 0 1 1 1 4 2 1 1 4 3 1 0 0 1 1 2 0 0 0 0 0 0 0
Nucleolus 4 10 9 3 4 10 16 7 36 36 45 65 2 4 2 3 3 2 5 2 14 0 4 13
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 1 12 0 5 3 6 6 4 4 5 4 0 0 0 0 0 1 1 1 4 0 0 1
Vac/Vac Membrane 2 2 4 1 6 3 4 3 2 2 3 1 0 1 2 3 7 1 7 10 8 1 2 9
Unique Cell Count 203 181 234 233 317 289 385 386 263 303 366 502 16 149 139 125 97 65 207 190 244 40 124 156
Labelled Cell Count 210 243 255 241 330 320 447 426 380 416 518 715 18 156 142 142 112 68 207 190 244 40 124 156


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.4 4.6 7.2 6.4 6.7 6.1 5.6 5.9 4.9 5.1 4.6 4.8 5.4 6.6 6.0 5.5 7.9 7.6 5.4 7.6 7.8
Std Deviation (1e-4) 1.3 0.8 2.1 1.8 1.8 2.9 1.4 1.7 1.6 1.6 0.9 0.9 0.8 1.3 1.5 1.1 4.3 2.0 0.5 1.9 1.9
Intensity Change (Log2) – – – -0.17 -0.11 -0.25 -0.38 -0.3 -0.57 -0.52 -0.64 -0.61 -0.43 -0.13 -0.27 -0.39 0.12 0.06 -0.42 0.06 0.1


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.8186 1.8022 1.5453 1.4534 1.2877 1.6229 4.5003 4.579 4.5801 4.1532 4.3059 4.7485 1.9691 2.3373 1.8562 1.7766 2.234 1.9098
Actin 0.0178 0 0.0082 0 0.0037 0.0002 0.0041 0 0.0013 0 0 0 0.0008 0 0.0117 0.0017 0.0171 0.0113
Bud 0.0002 0 0.0004 0 0.0001 0 0.0003 0 0 0 0 0 0.0002 0 0.0003 0.0001 0.0007 0.0001
Bud Neck 0.0006 0.0001 0.0036 0.0001 0.0005 0.0016 0.0009 0.0001 0.0004 0.0001 0.0003 0.0005 0.0023 0.0001 0.0003 0.0001 0.0012 0.0011
Bud Periphery 0.0005 0 0.001 0 0.0004 0.0001 0.0004 0 0.0001 0 0 0 0.0005 0 0.0003 0.0001 0.0012 0.0004
Bud Site 0.0007 0 0.004 0 0.0002 0.0001 0.0021 0 0.0001 0 0.0001 0.0001 0.0007 0.0006 0.007 0.0005 0.0038 0.0002
Cell Periphery 0.0002 0 0.0003 0 0.0001 0 0.0002 0 0 0 0 0 0.0001 0 0.0001 0 0.0002 0.0001
Cytoplasm 0.0013 0.0005 0.0002 0 0.0003 0.0004 0.0036 0.0008 0.0002 0.0001 0.0001 0 0.0102 0.0016 0.0016 0.0003 0.0012 0.0004
Cytoplasmic Foci 0.0089 0 0.003 0 0.0061 0.0001 0.0083 0 0.0004 0 0 0.0005 0.0035 0.0001 0.0064 0.0089 0.0007 0.0064
Eisosomes 0.0001 0 0.0002 0 0.0003 0 0 0 0 0 0 0 0 0 0.0001 0.0001 0.0003 0
Endoplasmic Reticulum 0.0011 0 0.0004 0 0.0021 0.0003 0.0031 0.0002 0.0002 0 0 0 0.0015 0.0001 0.0003 0.0007 0.0026 0.0004
Endosome 0.021 0 0.0046 0 0.006 0.0005 0.0111 0.0001 0.0013 0 0.0001 0.0004 0.0068 0.0001 0.0028 0.0025 0.005 0.0046
Golgi 0.0068 0 0.0035 0 0.0077 0 0.0035 0 0.0004 0 0 0.0004 0.0005 0 0.0017 0.0012 0.0011 0.0015
Lipid Particles 0.0123 0 0.0056 0 0.0443 0.0001 0.0145 0 0.0012 0 0 0.0052 0.0019 0 0.0037 0.0196 0.0012 0.0046
Mitochondria 0.0271 0.0001 0.0034 0.0001 0.038 0.0003 0.0024 0 0.0005 0 0.0002 0.0011 0.0014 0.0002 0.0089 0.0042 0.0099 0.0041
None 0.0011 0 0.0002 0 0.0002 0.0002 0.0014 0.0001 0.0005 0 0.0007 0 0.0059 0.0069 0.0003 0.001 0.0012 0.0004
Nuclear Periphery 0.0063 0.0035 0.0035 0.0005 0.007 0.0062 0.0125 0.0047 0.0024 0.0005 0.0015 0.0004 0.0184 0.0006 0.0013 0.0012 0.0169 0.0046
Nucleolus 0.0273 0.0165 0.0174 0.0133 0.0614 0.0537 0.0166 0.0111 0.0107 0.0107 0.0421 0.0437 0.023 0.016 0.0165 0.0121 0.0304 0.0329
Nucleus 0.8558 0.9736 0.9336 0.9641 0.8065 0.9329 0.8832 0.9791 0.9783 0.9876 0.949 0.944 0.8911 0.9713 0.9239 0.9401 0.8956 0.9133
Peroxisomes 0.0033 0 0.0031 0 0.0025 0 0.0097 0 0.0003 0 0 0.0018 0.0003 0 0.0009 0.003 0.0007 0.0014
Punctate Nuclear 0.0056 0.0055 0.0019 0.0219 0.0097 0.0027 0.0179 0.0037 0.0013 0.0008 0.0055 0.0014 0.0278 0.0019 0.0112 0.0019 0.007 0.0112
Vacuole 0.0012 0 0.0012 0 0.0006 0.0005 0.0031 0 0.0002 0 0.0001 0.0001 0.002 0.0002 0.0004 0.0003 0.001 0.0004
Vacuole Periphery 0.0008 0 0.0007 0 0.0021 0.0002 0.0011 0 0.0002 0 0.0001 0.0001 0.001 0 0.0002 0.0004 0.0009 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 9.1248 5.0197 9.3121 9.1438 11.8308 15.4335 13.323 10.2767 10.0582 12.6132
Translational Efficiency 1.1562 2.9735 1.1492 1.2971 0.89 0.798 0.8803 1.266 1.489 0.7602

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
43 528 2567 1468 1959 2460 156 1751 2002 2988 2723 3219

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 739.19 817.73 974.14 928.83 764.20 910.59 1044.90 965.92 763.66 894.18 978.19 949.01
Standard Deviation 137.08 157.64 129.12 132.73 101.18 111.85 123.31 139.47 102.15 126.28 129.84 137.68
Intensity Change Log 2 — 0.145679 0.398184 0.329469 — 0.252851 0.451343 0.337953 — 0.201151 0.425450 0.333788

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002646 0.001297 0.000567 0.001108 0.000306 0.000275 0.001735 0.000736 0.000357 0.000455 0.000634 0.000906
Bud Neck 0.008505 0.011358 0.030896 0.030549 0.005206 0.009593 0.011836 0.027646 0.005277 0.009905 0.029804 0.028970
Bud Site 0.007155 0.002662 0.001321 0.006148 0.000732 0.001193 0.001627 0.002069 0.000870 0.001453 0.001339 0.003929
Cell Periphery 0.000409 0.000242 0.000061 0.000183 0.000106 0.000093 0.000064 0.000087 0.000113 0.000119 0.000062 0.000131
Cytoplasm 0.004095 0.006360 0.001125 0.012196 0.002470 0.003093 0.001013 0.003908 0.002505 0.003670 0.001119 0.007688
Cytoplasmic Foci 0.032889 0.001808 0.000013 0.002434 0.000130 0.000492 0.000056 0.000200 0.000834 0.000724 0.000015 0.001219
Eisosomes 0.000154 0.000042 0.000029 0.000033 0.000017 0.000022 0.000056 0.000025 0.000020 0.000025 0.000030 0.000029
Endoplasmic Reticulum 0.020503 0.006785 0.002520 0.005636 0.002227 0.003360 0.006976 0.004324 0.002620 0.003965 0.002775 0.004922
Endosome 0.008795 0.000702 0.000173 0.003468 0.000142 0.000857 0.000236 0.000515 0.000327 0.000830 0.000176 0.001862
Golgi 0.015588 0.000430 0.000101 0.002190 0.000070 0.000196 0.000151 0.000363 0.000404 0.000237 0.000104 0.001196
Lipid Particles 0.061328 0.000714 0.000030 0.001501 0.000079 0.000365 0.000227 0.000071 0.001394 0.000426 0.000041 0.000723
Mitochondria 0.048926 0.001927 0.001168 0.006014 0.000478 0.003418 0.001201 0.001787 0.001518 0.003155 0.001170 0.003715
Mitotic Spindle 0.028533 0.001599 0.001674 0.035052 0.001082 0.003847 0.000544 0.002303 0.001672 0.003449 0.001609 0.017238
None 0.014026 0.019744 0.001973 0.009100 0.005575 0.003508 0.002805 0.004086 0.005757 0.006377 0.002020 0.006373
Nuclear Periphery 0.001136 0.000309 0.000388 0.002509 0.000210 0.000832 0.000334 0.000745 0.000230 0.000740 0.000385 0.001550
Nuclear Periphery Foci 0.006185 0.001537 0.000055 0.001434 0.000249 0.000313 0.000184 0.000198 0.000376 0.000529 0.000062 0.000762
Nucleolus 0.067979 0.051149 0.022300 0.017403 0.032049 0.034700 0.027567 0.012623 0.032821 0.037607 0.022602 0.014803
Nucleus 0.613970* 0.887148* 0.934903* 0.851128* 0.948399* 0.930297* 0.939461* 0.935462* 0.941216* 0.922673* 0.935164* 0.897003*
Peroxisomes 0.044245 0.002715 0.000158 0.001468 0.000192 0.000560 0.000821 0.000161 0.001138 0.000940 0.000196 0.000757
Vacuole 0.006070 0.001000 0.000401 0.006975 0.000166 0.002094 0.002949 0.002107 0.000293 0.001901 0.000547 0.004327
Vacuole Periphery 0.006862 0.000472 0.000145 0.003471 0.000116 0.000892 0.000157 0.000581 0.000261 0.000818 0.000146 0.001899

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.08 3.23 1.98 -0.62 -13.91 0.60 -9.56 -9.58 -18.18 6.94 -1.77 -7.42 -12.82 -16.99 -9.87
Bud Neck -0.98 -6.95 -6.45 -10.52 0.22 -5.67 -6.78 -19.80 -15.85 -9.64 -6.67 -25.90 -24.79 -19.53 -0.31
Bud Site 0.97 1.27 0.25 -3.89 -6.82 -1.27 -4.53 -4.84 -4.28 -0.70 -1.74 -2.61 -7.42 -7.07 -7.45
Cell Periphery 1.29 2.96 2.25 2.27 -6.25 0.40 0.81 0.56 0.36 -0.87 -0.17 1.58 0.04 0.53 -6.64
Cytoplasm -1.51 2.70 -3.48 -1.69 -6.33 -0.85 2.50 -2.25 -1.35 -4.55 -1.66 3.00 -4.96 -3.41 -7.87
Cytoplasmic Foci 3.20 3.40 3.29 1.16 -3.42 -3.18 1.75 -0.33 2.57 -1.18 0.30 3.54 1.07 1.03 -3.84
Eisosomes 3.77 4.15 3.85 0.54 -6.39 -4.06 -8.85 -9.97 -4.84 6.97 -3.85 -10.10 -10.43 -6.68 -0.17
Endoplasmic Reticulum 2.66 3.50 2.69 0.26 -16.60 -5.02 -7.92 -13.75 -5.30 4.92 -5.73 -3.18 -14.91 -7.35 -15.40
Endosome 1.96 2.09 1.69 -3.10 -5.25 -4.76 -3.92 -2.61 1.61 -1.24 -3.27 1.39 -4.21 -1.27 -5.60
Golgi 2.93 2.99 2.82 -1.55 -2.51 -2.25 -5.58 -1.34 -0.58 -0.74 1.33 2.31 -0.92 -2.01 -2.68
Lipid Particles 3.80 3.84 3.79 -0.04 -1.44 -2.79 -3.23 -0.48 2.71 3.15 2.37 3.43 2.23 0.19 -1.50
Mitochondria 3.36 3.40 3.19 -3.41 -4.36 -5.11 -10.27 -13.26 2.13 -4.56 -2.85 0.34 -3.56 0.07 -5.57
Mitotic Spindle 1.70 1.64 0.03 -7.87 -7.65 -2.49 0.59 -3.16 -0.56 -4.31 -1.78 -0.86 -7.76 -6.55 -7.63
None -0.95 2.10 1.27 3.85 -5.69 2.30 3.50 1.96 -0.50 -1.96 -0.69 5.19 0.75 1.52 -6.56
Nuclear Periphery 1.84 1.40 -3.07 -7.35 -6.79 -4.52 -4.50 -6.04 -2.03 -4.29 -4.43 -6.17 -9.49 -5.80 -8.01
Nuclear Periphery Foci 1.51 2.17 1.74 0.76 -4.39 0.02 0.25 0.25 0.39 -0.02 -0.65 2.43 -1.36 -0.77 -5.06
Nucleolus 1.30 2.68 3.28 8.68 5.95 -1.31 1.91 9.40 10.80 2.55 -2.34 3.14 10.36 13.75 7.41
Nucleus -4.72 -5.40 -4.42 2.04 9.61 5.11 3.14 7.62 2.24 2.23 4.94 4.99 11.05 6.34 7.85
Peroxisomes 2.76 2.92 2.88 1.38 -1.69 -2.12 -5.97 0.30 2.15 6.03 0.43 2.59 1.84 1.64 -1.41
Vacuole 1.83 2.06 -0.85 -6.08 -6.72 -4.55 -4.49 -4.74 -0.78 2.23 -4.55 -4.41 -8.15 -4.71 -7.28
Vacuole Periphery 1.76 1.86 1.44 -2.15 -2.87 -3.21 -3.99 -2.20 1.33 -1.81 -2.60 1.33 -2.84 -0.54 -3.40
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA; relocalizes to the cytosol in response to hypoxia
Localization
Cell Percentages nucleus (98%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Luc7

Luc7


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Luc7-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available