Standard name
Human Ortholog
Description Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction with Pho4p; relocalizes to the cytosol in response to hypoxia
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.1 0.11 0 0 0.05 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.09 0 0 0 0 0 0 0 0.15 0.09 0.34 0.12 0 0 0 0 0.06 0 0 0 0 0 0 0
Nucleus 0.94 0.93 0.97 0.96 0.95 0.92 0.93 0.92 0.87 0.89 0.78 0.85 0.92 0.88 0.83 0.93 0.9 0.86 0.9 0.91 0.9 0.83 0.78 0.68
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.08 0 0 0 0 0 0 0.06 0.11 0.07 0.13 0.12 0 0 0 0 0 0 0 0 0 0 0 0.07
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.07 0 0 0 0.05 0.1 0.15
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 1 0 1 2 1 0 0 0 0 1 1 1 2 1 0 1 2
Bud Neck 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 2 0 2 10 6 4 0 0 0 0 1 1 – – – – – –
Cell Periphery 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 5 12 2 8 14 11 20 13 10 8 14 4 10 24 35 5 5 19 1 1 0 0 5 2
Endoplasmic Reticulum 0 0 0 1 0 0 1 0 0 0 0 0 0 1 0 2 4 3 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 1 2 1 0 0 0 2 1 8 1 2 6 0 1 0 0 0 0
Golgi 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 2 1 1 1 0 0 0 0 0
Mitochondria 20 5 1 1 1 12 15 21 41 32 112 58 0 2 2 10 17 11 3 4 1 0 1 4
Nucleus 210 316 138 247 326 332 528 459 240 311 252 413 141 217 263 250 266 321 203 314 135 44 120 151
Nuclear Periphery 1 1 0 0 0 1 5 1 3 3 1 2 2 4 6 4 2 2 0 0 0 0 0 0
Nucleolus 18 7 0 1 3 10 12 32 31 26 41 56 4 4 9 6 10 6 7 6 2 1 5 16
Peroxisomes 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 0 0 0 0 0
SpindlePole 1 1 1 0 1 1 1 4 0 3 1 3 0 2 1 3 0 3 1 0 1 0 0 5
Vac/Vac Membrane 1 9 1 1 4 7 10 3 3 4 3 15 0 2 8 13 10 25 5 8 5 2 15 33
Unique Cell Count 224 338 142 258 344 359 565 498 277 350 325 486 154 246 318 269 296 372 227 344 151 54 155 222
Labelled Cell Count 256 353 143 260 349 374 596 536 331 398 433 557 159 257 334 296 319 400 227 344 151 54 155 222


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.7 7.0 7.3 7.2 8.0 6.7 6.7 6.7 5.8 6.1 5.1 5.9 8.2 8.0 7.8 8.8 8.6 8.3 7.4 7.7 8.3
Std Deviation (1e-4) 0.8 1.2 1.0 1.5 1.4 1.4 1.3 1.2 1.3 1.3 1.3 1.3 2.4 2.1 2.9 2.1 2.1 1.9 1.1 2.3 3.1
Intensity Change (Log2) – – – -0.02 0.13 -0.14 -0.13 -0.13 -0.34 -0.26 -0.54 -0.32 0.15 0.12 0.08 0.26 0.23 0.18 0.0 0.06 0.19

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 2.2 3.2 3.5 0 0 1.9
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 4.5 3.4 7.8 4.0 0 0 0 0 2.5 0
Nucleus -0.7 -1.2 -2.0 -1.7 -2.1 -3.4 -3.0 -5.3 -3.9 -2.1 -3.1 -4.3 -1.8 -2.7 -3.6
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 3.1 4.1 3.3 4.4 4.2 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.8

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.6772 3.7881 3.4542 3.3398 2.8167 3.2672 2.4285 3.1534 2.6463 1.9257 2.4146 2.3573 2.3146 2.219 1.9811 1.9717 2.3353 1.8314
Actin 0 0 0 0 0 0 0.0114 0 0.0109 0.0006 0.006 0.0014 0.0167 0 0.0052 0.0063 0.0284 0.0022
Bud 0 0 0 0 0 0 0.0004 0 0.0003 0 0.0034 0.0001 0.0003 0 0.0004 0.0006 0.0005 0.0001
Bud Neck 0 0 0 0 0.0002 0.0005 0.0008 0 0.0005 0.0002 0.0022 0.0032 0.0005 0 0.0002 0.0002 0.0006 0.0008
Bud Periphery 0 0 0 0 0 0 0.0006 0 0.0007 0.0001 0.0063 0.0004 0.0006 0 0.0004 0.0013 0.0014 0.0003
Bud Site 0 0 0 0 0 0 0.0031 0 0.0027 0.0001 0.0215 0.0002 0.0014 0 0.0029 0.0008 0.0013 0.0002
Cell Periphery 0 0 0 0 0 0 0.0003 0 0.0002 0 0.0023 0.0001 0.0002 0 0.0002 0.0002 0.0005 0.0001
Cytoplasm 0 0 0 0 0 0 0.0028 0 0.0007 0.0009 0.0019 0.0004 0.0157 0 0.0089 0.0051 0.0005 0.0003
Cytoplasmic Foci 0 0 0 0 0 0 0.0172 0 0.0065 0.03 0.0124 0.0024 0.0082 0 0.0062 0.0028 0.0092 0.0062
Eisosomes 0 0 0 0 0 0 0.0002 0 0.0001 0 0.0001 0 0.0002 0 0.0001 0.0004 0.0004 0
Endoplasmic Reticulum 0 0 0 0 0 0 0.0009 0 0.0005 0.0002 0.0008 0.0005 0.0003 0 0.0015 0.0013 0.001 0.0002
Endosome 0 0 0 0 0 0 0.0137 0 0.0062 0.0051 0.0174 0.0106 0.0066 0 0.0073 0.0047 0.0084 0.0079
Golgi 0 0 0 0 0 0 0.0054 0 0.0036 0.002 0.0153 0.0069 0.0061 0 0.0031 0.0051 0.0165 0.0047
Lipid Particles 0 0 0 0 0 0 0.0205 0 0.0069 0.0168 0.0278 0.0025 0.018 0 0.0016 0.0068 0.0308 0.0021
Mitochondria 0.0001 0 0 0 0.0001 0 0.0042 0.0001 0.0058 0.0004 0.0272 0.0057 0.0062 0.0001 0.005 0.1479 0.0773 0.0041
None 0 0 0 0 0 0 0.0197 0 0.0003 0.0003 0.0009 0.0003 0.0015 0 0.0005 0.0445 0.0005 0.0001
Nuclear Periphery 0.0001 0.0002 0.0003 0.0002 0.0002 0.0001 0.0059 0.0002 0.0054 0.0006 0.0044 0.0058 0.0021 0.0002 0.0006 0.0011 0.0248 0.0033
Nucleolus 0.0108 0.0129 0.0087 0.0054 0.0424 0.0346 0.0144 0.0055 0.0131 0.0038 0.0746 0.0407 0.0141 0.0094 0.0094 0.0042 0.0667 0.0346
Nucleus 0.9888 0.9867 0.9909 0.9943 0.956 0.9645 0.8541 0.994 0.9196 0.9052 0.7406 0.9134 0.882 0.9901 0.9435 0.7606 0.6979 0.9294
Peroxisomes 0 0 0 0 0 0 0.0047 0 0.0107 0.0241 0.0071 0.0012 0.0152 0 0.0014 0.0021 0.0217 0.0005
Punctate Nuclear 0.0001 0.0002 0.0001 0.0001 0.0008 0.0001 0.0162 0.0001 0.0032 0.0096 0.0026 0.0021 0.0026 0.0001 0.0006 0.0011 0.0012 0.0005
Vacuole 0 0 0 0 0 0 0.0022 0 0.0016 0.0001 0.0198 0.0013 0.0008 0 0.0008 0.0011 0.0033 0.001
Vacuole Periphery 0 0 0 0 0 0 0.0012 0 0.0008 0 0.0055 0.0005 0.0005 0 0.0003 0.002 0.0072 0.0011

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 9.195 7.0455 1.7427 11.4178 8.5155 7.2207 10.6856 11.0184 11.0848 14.2466
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
442 1559 207 1189 1604 2131 300 2814 2046 3690 507 4003

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 731.76 745.53 1211.49 1175.33 819.06 823.62 1101.61 1206.22 800.20 790.63 1146.47 1197.04
Standard Deviation 92.02 163.05 134.76 170.60 106.48 120.46 113.08 168.07 109.59 145.26 133.78 169.41
Intensity Change Log 2 — 0.026896 0.727340 0.683623 — 0.008010 0.427573 0.558452 — 0.016952 0.576796 0.618870

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000133 0.000521 0.002153 0.000960 0.000317 0.000311 0.001222 0.000404 0.000277 0.000400 0.001602 0.000569
Bud Neck 0.001149 0.006470 0.016222 0.022113 0.004337 0.007931 0.005791 0.033268 0.003648 0.007314 0.010050 0.029955
Bud Site 0.000175 0.001019 0.002149 0.004634 0.000695 0.000970 0.001156 0.002349 0.000582 0.000991 0.001561 0.003028
Cell Periphery 0.000062 0.000250 0.000079 0.000074 0.000066 0.000142 0.000088 0.000066 0.000065 0.000188 0.000085 0.000069
Cytoplasm 0.003649 0.004720 0.000373 0.001836 0.002207 0.000988 0.001443 0.001578 0.002519 0.002565 0.001006 0.001655
Cytoplasmic Foci 0.000185 0.000250 0.000066 0.001035 0.000533 0.000378 0.000195 0.000170 0.000458 0.000324 0.000142 0.000427
Eisosomes 0.000012 0.000021 0.000080 0.000035 0.000018 0.000020 0.000053 0.000029 0.000016 0.000020 0.000064 0.000030
Endoplasmic Reticulum 0.001337 0.004059 0.005950 0.003355 0.002905 0.003560 0.007215 0.002365 0.002566 0.003771 0.006699 0.002659
Endosome 0.000206 0.000403 0.000197 0.002342 0.000312 0.000853 0.000212 0.000430 0.000289 0.000663 0.000206 0.000998
Golgi 0.000056 0.000096 0.000155 0.002873 0.000349 0.000316 0.000095 0.000466 0.000286 0.000223 0.000120 0.001181
Lipid Particles 0.000204 0.000114 0.000199 0.000132 0.000272 0.000196 0.000254 0.000023 0.000257 0.000161 0.000232 0.000056
Mitochondria 0.000336 0.001022 0.002152 0.002976 0.001912 0.002320 0.000912 0.002186 0.001571 0.001771 0.001419 0.002421
Mitotic Spindle 0.002024 0.000972 0.000247 0.016672 0.002684 0.003143 0.001003 0.006062 0.002541 0.002226 0.000695 0.009213
None 0.006468 0.018232 0.000881 0.001571 0.002542 0.001872 0.002979 0.001401 0.003390 0.008784 0.002122 0.001452
Nuclear Periphery 0.000165 0.000330 0.000362 0.001476 0.000417 0.001094 0.000334 0.001254 0.000363 0.000771 0.000346 0.001320
Nuclear Periphery Foci 0.000620 0.000337 0.000091 0.001662 0.000233 0.000738 0.000180 0.000158 0.000317 0.000568 0.000144 0.000605
Nucleolus 0.026901 0.017612 0.014851 0.010081 0.020195 0.016465 0.011867 0.005311 0.021643 0.016950 0.013085 0.006728
Nucleus 0.955869 0.942278 0.949536 0.918826 0.958824 0.955164 0.961885 0.940780 0.958186 0.949719 0.956843 0.934259
Peroxisomes 0.000170 0.000229 0.001167 0.000279 0.000664 0.000271 0.000432 0.000056 0.000557 0.000253 0.000732 0.000122
Vacuole 0.000183 0.000612 0.002889 0.005541 0.000335 0.001777 0.002566 0.001239 0.000302 0.001285 0.002698 0.002517
Vacuole Periphery 0.000097 0.000453 0.000201 0.001527 0.000183 0.001490 0.000116 0.000407 0.000164 0.001052 0.000151 0.000739

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -11.38 -15.30 -18.70 -11.21 8.18 0.14 -13.30 -7.92 -8.77 10.76 -4.45 -18.94 -16.33 -12.95 13.49
Bud Neck -7.94 -11.84 -19.50 -14.52 -5.53 -5.38 -4.24 -28.30 -23.77 -20.46 -7.36 -10.14 -33.36 -28.00 -19.40
Bud Site -5.27 -12.09 -4.52 -3.57 -1.52 -0.69 -2.44 -3.75 -3.50 -2.27 -1.31 -5.11 -5.44 -5.13 -2.34
Cell Periphery -2.80 -1.45 -1.08 2.56 1.05 -0.81 -0.74 0.04 0.84 0.97 -2.00 -1.25 -0.41 1.95 1.36
Cytoplasm -0.67 1.93 1.04 4.54 -4.39 1.47 0.05 0.82 -1.13 0.50 -0.26 1.36 1.27 2.52 -0.52
Cytoplasmic Foci -0.96 1.13 -1.59 -1.08 -2.20 0.77 1.72 2.34 2.29 1.00 0.75 2.08 1.47 1.13 -0.82
Eisosomes -5.16 -14.82 -16.43 -8.27 9.02 -1.11 -12.09 -8.34 -6.61 9.26 -2.82 -18.03 -13.87 -9.89 13.17
Endoplasmic Reticulum -10.04 -10.73 -10.25 0.97 6.00 -2.57 -11.13 2.37 4.55 12.29 -6.12 -14.31 -2.30 4.91 13.76
Endosome -1.52 -0.84 -2.78 -2.28 -2.64 -2.32 -0.11 -0.02 2.27 0.07 -2.54 -0.26 -2.23 0.20 -2.30
Golgi -2.04 -6.42 -1.99 -1.94 -1.79 0.10 0.92 0.09 0.01 -0.89 0.30 0.65 -1.26 -1.68 -1.95
Lipid Particles 1.08 -1.14 0.69 -1.13 3.30 0.71 -0.69 3.33 3.05 7.18 1.30 -0.90 3.23 3.00 8.26
Mitochondria -4.91 -15.43 -7.49 -5.46 -1.91 -0.51 1.11 -0.79 -0.30 -4.52 -0.35 -0.21 -1.95 -2.56 -4.20
Mitotic Spindle 0.52 0.77 -4.67 -5.78 -6.00 -0.33 0.52 -2.92 -2.91 -3.82 0.27 1.07 -5.31 -6.40 -7.17
None -5.04 4.31 3.29 8.15 -5.66 1.74 -0.57 2.21 -0.11 1.05 -5.84 1.16 3.86 7.90 0.45
Nuclear Periphery -4.71 -7.19 -5.92 -5.20 -4.45 -1.87 -1.05 -4.43 -0.67 -4.15 -1.93 -2.32 -6.39 -2.57 -5.72
Nuclear Periphery Foci 0.56 0.91 -0.83 -2.25 -2.75 -1.91 -0.80 1.53 2.30 1.24 -1.35 0.01 -0.70 0.81 -0.64
Nucleolus 3.14 3.00 3.45 0.84 0.17 2.67 2.67 6.10 3.64 0.78 3.77 3.65 6.73 3.75 1.01
Nucleus 2.48 2.71 7.06 5.96 5.42 1.00 1.86 9.76 8.34 4.01 2.84 3.26 12.18 9.92 6.18
Peroxisomes -1.49 -8.41 -4.03 -2.68 6.98 1.51 0.73 2.43 2.11 8.57 1.54 -1.29 2.10 1.67 10.28
Vacuole -3.59 -6.51 -4.95 -4.44 -0.06 -3.19 -2.79 -4.96 0.58 2.35 -3.72 -3.92 -6.71 -2.87 2.49
Vacuole Periphery -1.39 -4.59 -2.92 -1.25 -2.42 -2.85 1.00 -1.37 2.56 -2.08 -3.09 -0.52 -3.08 1.86 -3.05
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction with Pho4p; relocalizes to the cytosol in response to hypoxia
Localization
Cell Percentages nucleus (99%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Pho2

Pho2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pho2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available