Standard name
Human Ortholog
Description Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport and NPC biogenesis; also plays roles in several processes that may require localization of genes or chromosomes at the nuclear periphery, including double-strand break repair, transcription and chromatin silencing; homologous to human NUP107
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 – 0 0 0 0 0.06 0.14 0.07 0.07 0.12 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.14 0.12 0.14 0.12 0.33 0.34 0.36 – 0.48 0.55 0.4 0 0 0 0.08 0.1 0.05 0 0 0 0.07 0.15 0.17
Nucleus 0 0.1 0 0 0 0 0 0 – 0.05 0 0 0.08 0 0.06 0.15 0.15 0.13 0 0 0 0 0 0
Nuclear Periphery 0.83 0.81 0.84 0.77 0.76 0.65 0.64 0.61 – 0.6 0.49 0.57 0.88 0.85 0.67 0.61 0.57 0.54 0.87 0.82 0.87 0.82 0.71 0.61
Nucleolus 0.11 0.07 0.19 0.26 0.19 0.31 0.3 0.31 – 0.35 0.39 0.35 0.09 0.08 0.06 0.11 0.14 0.14 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.28 0.23 0.17 0.08 0.16 0.06 0.06 0.05 – 0 0 0.06 0.16 0.17 0.29 0.28 0.25 0.26 0 0.07 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 1 0 0 0 – 0 0 0 0 1 0 0 0 0 0 0 4 0 1 2
Bud 0 0 0 0 0 0 1 4 – 1 8 1 0 0 0 0 1 0 1 1 3 0 1 2
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 1 2 1 – 6 8 5 0 0 2 0 1 0 – – – – – –
Cell Periphery 1 0 0 0 1 0 0 0 – 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
Cytoplasm 5 3 8 9 10 14 10 10 – 8 8 1 1 8 30 20 17 18 0 0 1 0 0 0
Endoplasmic Reticulum 6 0 2 2 1 1 0 4 – 3 0 2 2 1 0 10 8 6 0 0 1 0 1 2
Endosome 3 0 13 4 10 14 21 21 – 10 6 16 1 1 5 5 10 3 1 5 8 1 12 14
Golgi 1 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 1 4 1 7 11
Mitochondria 11 37 51 39 31 152 177 236 – 334 300 230 0 1 0 23 24 7 8 9 9 8 47 45
Nucleus 11 26 6 12 7 13 9 21 – 35 15 16 7 5 12 42 36 19 6 2 3 1 0 0
Nuclear Periphery 204 216 347 214 204 298 334 405 – 414 264 325 75 112 143 169 135 78 236 250 407 100 229 167
Nucleolus 26 18 78 72 52 142 157 202 – 243 211 203 8 10 13 31 32 21 2 8 4 2 3 3
Peroxisomes 0 0 0 0 0 1 3 1 – 2 1 2 0 0 0 0 1 0 0 0 0 0 4 5
SpindlePole 0 0 1 0 1 2 4 2 – 4 3 2 1 1 8 0 2 0 0 1 3 0 1 0
Vac/Vac Membrane 68 61 69 23 44 29 30 35 – 16 17 36 14 23 63 78 59 37 11 20 8 2 6 12
Unique Cell Count 246 268 412 279 269 459 520 659 692 544 573 85 132 214 275 236 145 272 305 467 122 323 273
Labelled Cell Count 336 361 575 375 362 667 748 942 1076 841 839 109 164 276 378 326 189 272 305 467 122 323 273


Nuclear Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 12.9 12.7 12.3 11.5 10.7 9.0 8.5 8.5 – 7.5 7.4 8.0 12.2 11.1 11.5 8.2 8.8 10.6 13.0 13.9 14.7
Std Deviation (1e-4) 3.8 3.3 3.0 3.4 3.4 2.8 2.1 2.5 – 2.3 2.3 2.3 2.9 2.8 3.5 2.3 3.1 3.6 2.8 2.7 2.8
Intensity Change (Log2) – – – -0.09 -0.2 -0.44 -0.53 -0.54 – -0.72 -0.73 -0.63 -0.01 -0.15 -0.1 -0.59 -0.48 -0.21 0.08 0.17 0.26


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cytoplasm 1.1 1.4 1.0 0 -0.5 – -1.1 -0.6 0 0 0 6.0 3.5 3.3 5.1
Endoplasmic Reticulum 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Endosome -1.4 0.4 -0.1 0.7 0 – -1.9 -2.3 -0.3 0 0 -0.6 -1.1 0.7 0
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Mitochondria 0.6 -0.3 7.2 7.6 8.4 – 12.1 13.6 9.5 -3.4 -4.0 -5.4 -1.7 -0.8 -2.6
Nucleus 2.3 1.1 1.4 0.3 1.8 – 3.1 1.4 1.4 0 0 2.9 7.0 6.9 5.8
Nuclear Periphery -2.5 -2.7 -6.5 -6.8 -7.9 – -8.5 -11.4 -9.1 0.9 0.2 -5.0 -6.8 -7.6 -7.4
Nucleolus 2.2 0.1 4.1 3.9 4.2 – 5.7 6.6 5.7 -2.1 -3.1 -4.3 -2.7 -1.8 -1.2
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Vacuole -3.2 -0.1 -4.9 -5.4 -6.1 – -8.7 -7.3 -5.2 -0.1 0.2 3.7 3.6 2.5 2.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 10.6512 9.6575 9.3608 8.8665 9.0529 9.1773 11.2245 12.0531 10.5861 9.7671 9.7166 9.9282 13.2286 12.0901 11.7687 11.0826 11.2475 11.2944
Actin 0.0129 0.0001 0.0044 0.0094 0.0007 0.0012 0.0004 0.0001 0.0168 0.0007 0.0005 0.0001 0.0003 0 0.0002 0.0001 0.0002 0
Bud 0.0001 0 0.0001 0.0001 0 0 0.0001 0 0.0001 0 0 0 0 0 0 0 0 0
Bud Neck 0.0012 0 0.0001 0.0003 0.0002 0 0.0002 0 0.0009 0 0 0 0.0001 0 0 0 0 0
Bud Periphery 0.0002 0 0.0001 0.0006 0.0002 0 0.0001 0 0.0003 0.0002 0.0001 0.0001 0.0001 0 0.0001 0.0001 0 0
Bud Site 0.0007 0 0.0001 0.0005 0.0001 0 0.0009 0 0.0007 0 0 0 0.0001 0 0 0 0 0
Cell Periphery 0.0001 0 0 0.0001 0.0001 0 0 0 0.0001 0 0 0 0 0 0 0 0 0
Cytoplasm 0.0026 0.0001 0.0004 0.0002 0.0001 0 0.0016 0 0.0012 0 0.0001 0 0.0001 0 0 0 0 0
Cytoplasmic Foci 0.0019 0 0.0004 0.0031 0.0001 0.0003 0.0251 0 0.0009 0 0.0007 0 0.0004 0 0.0002 0 0.0001 0.0001
Eisosomes 0.0002 0 0 0.0002 0 0 0 0 0.0001 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0024 0.0002 0.0005 0.0011 0.0015 0.0002 0.0005 0.0011 0.0056 0.0017 0.0005 0.0003 0.0005 0.0005 0.0004 0.0005 0.0002 0.0001
Endosome 0.0031 0.0002 0.0004 0.0022 0.0049 0.0012 0.0181 0.0002 0.0027 0.0004 0.0007 0.0002 0.0011 0.0003 0.0002 0.0001 0.0002 0.0001
Golgi 0.0011 0 0.0006 0.0017 0.0012 0.0008 0.0056 0.0001 0.0006 0.0003 0.0009 0.0001 0.0003 0.0001 0.0002 0.0001 0.0006 0.0001
Lipid Particles 0.0021 0.0002 0.0009 0.0069 0.0038 0.0012 0.0027 0.0008 0.0025 0.0014 0.0176 0.0005 0.0034 0.001 0.0091 0.0008 0.0197 0.002
Mitochondria 0.0014 0.0006 0.0007 0.0045 0.002 0.0005 0.0007 0.0011 0.0019 0.0015 0.0028 0.0014 0.0011 0.0132 0.0051 0.0005 0.0005 0.0013
None 0.0051 0 0.0002 0.0006 0.0002 0.0001 0.0002 0.0001 0.0005 0.0003 0.0002 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0
Nuclear Periphery 0.9142 0.9085 0.9412 0.9202 0.8707 0.9703 0.9057 0.926 0.8998 0.9457 0.9074 0.978 0.9515 0.9455 0.9454 0.9647 0.94 0.9793
Nucleolus 0.002 0.0018 0.0012 0.0009 0.0602 0.001 0.0002 0.0003 0.0006 0.0006 0.0041 0.0003 0.0041 0.0001 0.0004 0.0002 0.0069 0.0006
Nucleus 0.018 0.0644 0.021 0.0189 0.0256 0.0089 0.0011 0.0202 0.0167 0.0037 0.0081 0.0026 0.004 0.0015 0.0021 0.002 0.0023 0.0018
Peroxisomes 0.0017 0 0.0005 0.0068 0.0001 0.0004 0.0035 0 0.0001 0 0.0002 0 0.0001 0 0.0001 0 0 0
Punctate Nuclear 0.0046 0.0004 0.0028 0.0009 0.0013 0.0009 0.0008 0.0003 0.0009 0.0009 0.0301 0.0004 0.0025 0.0001 0.0003 0.0004 0.0017 0.0009
Vacuole 0.0008 0.001 0.0002 0.0005 0.0017 0.0002 0.0004 0.0004 0.0007 0.0005 0.0004 0.0003 0.0005 0.0007 0.0003 0.0002 0.0004 0.0002
Vacuole Periphery 0.0234 0.0223 0.0243 0.0205 0.0252 0.0128 0.0321 0.0492 0.0462 0.0419 0.0254 0.0157 0.0295 0.0367 0.0357 0.0302 0.0267 0.0133

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 26.0547 31.2058 27.5188 31.4529 25.2538 19.7198 33.0384 30.2459 27.7098 34.8855
Translational Efficiency 0.904 0.8521 0.8213 0.7676 0.8443 1.0067 0.7845 0.711 0.6808 0.6133

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
211 1275 248 342 2580 2116 2485 1125 2791 3391 2733 1467

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1419.61 1066.35 1515.47 1329.34 1107.01 1205.17 1436.27 1225.39 1130.64 1152.97 1443.46 1249.62
Standard Deviation 201.90 260.75 208.23 218.63 191.67 203.30 226.98 198.71 209.45 236.38 226.49 208.22
Intensity Change Log 2 — -0.412814 0.094271 -0.094784 — 0.122568 0.375659 0.146573 — -0.153551 0.224357 0.015962

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000471 0.001446 0.000647 0.000325 0.000313 0.000361 0.000449 0.000926 0.000325 0.000769 0.000467 0.000786
Bud Neck 0.003329 0.001439 0.002005 0.000950 0.000377 0.000435 0.000572 0.001950 0.000600 0.000812 0.000702 0.001717
Bud Site 0.002535 0.000646 0.000153 0.000060 0.000051 0.000103 0.000032 0.000269 0.000239 0.000307 0.000043 0.000220
Cell Periphery 0.000076 0.000210 0.000030 0.000017 0.000025 0.000029 0.000023 0.000049 0.000029 0.000097 0.000024 0.000042
Cytoplasm 0.000191 0.002707 0.000185 0.000061 0.000062 0.000189 0.000218 0.001034 0.000072 0.001136 0.000215 0.000807
Cytoplasmic Foci 0.002769 0.003280 0.000393 0.000862 0.000389 0.000761 0.000129 0.000895 0.000569 0.001708 0.000153 0.000887
Eisosomes 0.000011 0.000025 0.000010 0.000006 0.000008 0.000006 0.000005 0.000012 0.000008 0.000013 0.000005 0.000011
Endoplasmic Reticulum 0.002486 0.007760 0.002884 0.001893 0.001965 0.002052 0.000727 0.004465 0.002004 0.004198 0.000923 0.003865
Endosome 0.003848 0.003475 0.000428 0.000364 0.000482 0.000697 0.000114 0.001772 0.000736 0.001741 0.000142 0.001444
Golgi 0.005739 0.002609 0.000253 0.001042 0.000189 0.000332 0.000090 0.000695 0.000608 0.001188 0.000105 0.000776
Lipid Particles 0.001409 0.003850 0.000253 0.000556 0.001392 0.002054 0.000153 0.000579 0.001393 0.002729 0.000162 0.000574
Mitochondria 0.004275 0.009327 0.001979 0.001726 0.004888 0.005250 0.002614 0.004351 0.004842 0.006783 0.002557 0.003739
Mitotic Spindle 0.112816* 0.003971 0.023404 0.004178 0.001420 0.001286 0.002646 0.026166 0.009841 0.002296 0.004530 0.021040
None 0.000169 0.006364 0.000209 0.000159 0.000434 0.000367 0.000236 0.000851 0.000414 0.002622 0.000233 0.000690
Nuclear Periphery 0.559064* 0.485689* 0.648042* 0.637597* 0.641515* 0.692055* 0.763257* 0.473885* 0.635282* 0.614462* 0.752802* 0.512051*
Nuclear Periphery Foci 0.225407* 0.288431* 0.189970 0.290732* 0.301628* 0.249015* 0.158854 0.250290* 0.295865* 0.263835* 0.161678 0.259718*
Nucleolus 0.021812 0.074623 0.063485 0.027728 0.020878 0.016539 0.032622 0.100120 0.020949 0.038379 0.035422 0.083243
Nucleus 0.022404 0.073724 0.060805 0.017295 0.011816 0.011735 0.026913 0.125982 0.012616 0.035042 0.029988 0.100644
Peroxisomes 0.000904 0.001539 0.001218 0.000632 0.000583 0.000488 0.000566 0.001118 0.000608 0.000883 0.000625 0.001005
Vacuole 0.011117 0.010133 0.001361 0.002831 0.002537 0.004405 0.001487 0.001908 0.003185 0.006559 0.001476 0.002123
Vacuole Periphery 0.019167 0.018754 0.002286 0.010985 0.009050 0.011842 0.008293 0.002683 0.009815 0.014441 0.007748 0.004618

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.52 -0.74 1.87 10.08 2.73 -0.79 -3.27 -10.31 -5.52 -7.38 -6.46 -3.41 -9.10 -0.30 -5.71
Bud Neck 3.96 2.79 3.77 0.46 1.87 -0.42 -1.88 -8.39 -7.94 -8.17 -1.04 -0.64 -6.30 -6.08 -6.85
Bud Site 1.78 2.10 2.14 3.44 0.55 -1.45 0.21 -4.90 -3.05 -5.09 -0.22 2.06 0.16 0.67 -4.63
Cell Periphery -4.30 2.19 2.96 9.46 2.08 -0.70 0.25 -4.19 -3.21 -3.21 -7.60 0.75 -2.56 5.94 -2.55
Cytoplasm -4.83 0.66 1.94 5.42 1.41 -1.45 -1.62 -2.12 -1.76 -1.73 -5.51 -1.56 -2.08 0.74 -1.62
Cytoplasmic Foci -0.58 3.12 2.39 3.61 -1.96 -1.86 2.88 -1.80 -0.39 -2.73 -4.10 4.11 -1.39 2.40 -3.31
Eisosomes -2.94 0.42 2.14 6.28 1.92 2.13 3.36 -3.45 -5.65 -6.73 -3.57 3.17 -2.32 1.50 -5.72
Endoplasmic Reticulum -7.27 -0.82 1.30 10.29 2.27 -0.41 9.12 -8.56 -7.50 -13.46 -8.70 7.54 -7.53 0.84 -12.52
Endosome 0.24 2.94 3.03 6.01 0.61 -1.29 4.08 -2.57 -2.08 -3.34 -4.18 4.85 -1.81 0.67 -3.40
Golgi 0.97 1.79 1.47 1.63 -1.03 -1.31 1.38 -1.70 -1.14 -2.08 -1.83 2.08 -0.49 1.15 -2.35
Lipid Particles -3.21 3.24 2.41 4.78 -2.30 -1.80 7.68 4.22 4.13 -4.09 -3.70 8.11 4.74 6.26 -4.85
Mitochondria -2.53 1.22 1.39 7.58 0.40 -0.37 2.90 0.52 0.88 -2.53 -2.29 3.10 1.33 4.09 -2.07
Mitotic Spindle 6.64 5.21 6.52 -0.55 2.61 0.24 -2.43 -8.39 -8.47 -7.58 5.03 2.92 -4.23 -8.06 -6.62
None -6.27 0.84 1.10 6.77 1.27 1.07 3.33 -3.04 -3.49 -4.35 -6.24 3.44 -2.42 5.19 -4.14
Nuclear Periphery 2.38 -3.44 -3.74 -10.28 0.22 -8.15 -20.04 17.13 21.87* 29.05* 3.17 -19.32 14.22 11.75 27.45
Nuclear Periphery Foci -4.92 1.99 -4.56 -0.17 -8.16 10.26 32.38* 7.44 -0.01 -13.97 6.61 31.40 5.91 0.85 -17.39
Nucleolus -6.79 -3.74 -0.38 7.78 3.76 2.34 -5.07 -15.77 -16.65 -12.83 -7.77 -6.19 -14.96 -10.39 -10.75
Nucleus -4.63 -2.74 1.62 10.30 4.77 0.05 -7.06 -17.94 -17.84 -14.95 -9.92 -7.70 -16.99 -12.36 -12.92
Peroxisomes -1.31 -0.35 1.26 4.60 2.34 1.95 -0.07 -7.21 -9.06 -7.24 -3.69 -0.40 -5.28 -1.31 -5.15
Vacuole 0.27 2.87 2.47 5.24 -1.03 -3.03 2.76 1.20 3.49 -0.96 -5.42 3.89 1.96 6.72 -1.49
Vacuole Periphery -0.03 3.31 1.38 2.65 -3.36 -2.49 0.90 9.80 8.90 7.74 -4.51 2.34 5.65 9.39 3.57
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport and NPC biogenesis; also plays roles in several processes that may require localization of genes or chromosomes at the nuclear periphery, including double-strand break repair, transcription and chromatin silencing; homologous to human NUP107
Localization
Cell Percentages nuclear periphery (90%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Nup84

Nup84


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Nup84-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available