Standard name
Human Ortholog
Description Low complexity protein; mediates inhibition of Mep1p and Mep3p activity; hyperphosphorylated upon rapamycin treatment in a Tap42p-dependent manner; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; phosphorylation and localization regulated by TORC1-effector kinase, Npr1p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.05 0 0.12 – 0 0 0 0 0 0 0 0 0.2 0.12 0.07 0 0.12 0.07 0 0 0 0 0 0
Bud 0 0.1 0 – 0 0 0 0 0 0 0.08 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.82 0.82 0.75 – 0.58 0.49 0.37 0.33 0.42 0.4 0.38 0.41 0.77 0.91 0.92 0.86 0.93 0.9 0.74 0.57 0.8 0.68 0.55 0.6
Cytoplasm 0.45 0.59 0.46 – 0.85 0.83 0.89 0.88 0.84 0.84 0.87 0.79 0.21 0.15 0.17 0.16 0.14 0.21 0.16 0.31 0 0.16 0.28 0.27
Endoplasmic Reticulum 0 0 0.07 – 0.05 0 0 0 0 0 0 0 0 0 0 0.05 0 0.07 0 0 0 0 0 0.05
Endosome 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 – 0 0 0 0 0.1 0.1 0.09 0.14 0 0 0 0.12 0.05 0 0 0 0 0 0 0
Nucleus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 – 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 11 10 7 – 1 1 4 3 3 5 3 6 11 18 13 4 5 6 6 6 1 1 4 4
Bud 9 33 1 – 1 2 8 3 8 7 9 6 2 2 1 0 1 0 1 2 0 0 0 1
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 24 2 1 6 4
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 181 269 44 – 42 83 89 97 76 71 44 64 43 132 160 111 39 80 176 209 66 25 97 109
Cytoplasm 100 194 27 – 62 141 213 260 154 149 101 124 12 22 29 20 6 19 37 114 2 5 48 49
Endoplasmic Reticulum 3 1 4 – 4 3 2 12 2 1 0 4 0 1 2 6 0 6 5 5 2 0 4 8
Endosome 1 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 0
Golgi 1 0 0 – 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0
Mitochondria 0 2 1 – 0 0 2 4 18 18 10 22 1 0 0 15 2 2 0 1 2 0 3 0
Nucleus 1 1 0 – 0 2 2 2 1 1 0 1 2 1 0 5 3 1 0 0 1 0 1 0
Nuclear Periphery 2 1 0 – 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0
Nucleolus 1 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 – 0 0 0 0 0 0 0 0 0 2 1 1 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 – 1 0 4 6 1 2 0 0 3 0 0 1 0 0 1 4 0 0 1 0
Unique Cell Count 221 330 59 73 169 240 295 183 178 116 157 56 145 174 129 42 89 239 370 84 37 177 183
Labelled Cell Count 310 511 84 111 232 324 388 263 254 167 227 74 178 206 165 56 114 239 370 84 37 177 183


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 13.1 11.0 11.5 – 12.6 10.9 10.1 10.1 8.6 8.7 8.1 8.2 11.6 11.5 11.0 11.8 15.2 16.1 – 12.2 13.0
Std Deviation (1e-4) 2.0 1.6 2.0 – 1.9 1.6 1.4 1.5 1.3 1.4 1.2 1.3 2.1 1.9 1.9 2.5 2.5 3.4 – 2.4 2.5
Intensity Change (Log2) – – – – 0.13 -0.08 -0.19 -0.19 -0.42 -0.4 -0.51 -0.5 0.02 -0.0 -0.06 0.04 0.4 0.48 – 0.08 0.18

WT3RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches – 0 0 0 0 0 0 0 0 1.1 0.1 -1.0 0 0 -1.1
Bud – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery – -2.0 -3.4 -5.2 -6.0 -4.4 -4.6 -4.6 -4.4 0.3 3.1 3.5 1.9 2.4 2.5
Cytoplasm – 4.8 5.7 7.4 7.6 5.9 5.8 5.8 4.7 -2.8 -4.6 -4.5 -4.4 -3.3 -3.1
Endoplasmic Reticulum – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria – 0 0 0 0 0 0 0 2.6 0 0 0 2.3 0 0
Nucleus – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole – 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 9.3124 11.3668 10.1586 9.6957 8.094 10.2211 9.1148 11.1185 10.0239 10.9583 9.1464 10.9835 6.5101 9.6793 8.8251 8.4716 8.7636 8.9305
Actin 0.0412 0.0007 0.0086 0.0129 0.05 0.0001 0.0067 0.0078 0.0103 0.006 0.0379 0.0024 0.0748 0.0004 0.0092 0.0001 0.0166 0.0036
Bud 0.0013 0 0.0002 0.0007 0.0019 0.0001 0.0019 0.0002 0.0013 0.0005 0.0042 0.0004 0.0026 0.0001 0.0003 0.0002 0.0005 0.0001
Bud Neck 0.0053 0.0005 0.003 0.0019 0.0013 0.0035 0.0011 0.002 0.0085 0.0139 0.0035 0.0186 0.0172 0.0013 0.0036 0.0029 0.0019 0.0078
Bud Periphery 0.0078 0.0003 0.0027 0.0055 0.0113 0.0024 0.0105 0.0008 0.0037 0.0076 0.0194 0.0043 0.0142 0.0015 0.0019 0.005 0.0058 0.0024
Bud Site 0.0093 0.0125 0.014 0.0055 0.0038 0.0005 0.0106 0.0304 0.0392 0.0017 0.0103 0.0006 0.017 0.0192 0.0193 0.0005 0.0034 0.0004
Cell Periphery 0.7089 0.727 0.7747 0.8526 0.704 0.8868 0.686 0.7278 0.6132 0.708 0.6373 0.7561 0.5071 0.7074 0.6939 0.8157 0.7686 0.7794
Cytoplasm 0.1215 0.2504 0.1577 0.0822 0.0969 0.0948 0.2158 0.1756 0.287 0.1482 0.1456 0.1913 0.1557 0.2596 0.2328 0.154 0.1616 0.172
Cytoplasmic Foci 0.0145 0 0.0019 0.0025 0.0084 0 0.0023 0.0005 0.0034 0.0274 0.0186 0.0001 0.0254 0.0001 0.0035 0 0.0015 0.0005
Eisosomes 0.0036 0.0001 0.0005 0.0004 0.0026 0 0.0009 0.0003 0.0005 0.0001 0.0031 0.0001 0.0018 0.0002 0.0008 0.0001 0.0022 0.0001
Endoplasmic Reticulum 0.0212 0.0058 0.0094 0.0087 0.0117 0.0079 0.0105 0.0056 0.0065 0.0115 0.0066 0.008 0.017 0.0055 0.012 0.0129 0.0144 0.0137
Endosome 0.008 0 0.0034 0.0068 0.01 0 0.0093 0.0073 0.0041 0.0064 0.0027 0.0002 0.0369 0 0.0029 0 0.0014 0.001
Golgi 0.005 0.0001 0.0018 0.0065 0.0204 0 0.0006 0.0116 0.002 0.0137 0.0034 0.0003 0.0169 0.0001 0.0021 0 0.0016 0.0011
Lipid Particles 0.0084 0.0003 0.0075 0.0014 0.0072 0.0003 0.0009 0.0006 0.0092 0.0119 0.0042 0.0005 0.0438 0.0006 0.0027 0.0009 0.0037 0.0059
Mitochondria 0.0064 0 0.0018 0.0042 0.0222 0 0.0006 0.0248 0.0006 0.0008 0.015 0.0138 0.0096 0 0.0015 0 0.0005 0.0037
None 0.0145 0.0001 0.0007 0.0006 0.0003 0 0.0157 0.0002 0.0009 0.0008 0.0344 0.0001 0.0089 0.0001 0.0007 0 0.0094 0.0001
Nuclear Periphery 0.0033 0.0003 0.0009 0.0006 0.0007 0.0003 0.0048 0.0008 0.0005 0.0006 0.001 0.0002 0.0048 0.0004 0.001 0.0005 0.0011 0.0008
Nucleolus 0.0007 0 0.0005 0.0001 0.0001 0 0.0006 0 0.0003 0.0001 0.0019 0 0.0054 0 0.0002 0 0.0001 0.0001
Nucleus 0.0011 0.0001 0.0003 0.0002 0.0002 0.0001 0.0108 0.0002 0.0005 0.0005 0.0013 0.0001 0.0035 0.0001 0.0005 0.0001 0.0003 0.0002
Peroxisomes 0.0074 0 0.0047 0.0007 0.0396 0 0.0001 0.0001 0.0003 0.0346 0.0034 0 0.0194 0 0.0045 0 0.0002 0.0015
Punctate Nuclear 0.0029 0 0.0002 0.0001 0.0003 0 0.0034 0 0.0002 0.0005 0.0435 0 0.0055 0 0.0003 0 0.0002 0.0003
Vacuole 0.0071 0.0018 0.0053 0.0059 0.0064 0.003 0.0065 0.0028 0.0075 0.0053 0.0024 0.0027 0.0108 0.0033 0.0064 0.0069 0.0049 0.0051
Vacuole Periphery 0.0006 0 0.0002 0.0002 0.0006 0 0.0004 0.0005 0.0002 0.0001 0.0002 0.0001 0.0016 0 0.0001 0 0.0002 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 70.8266 63.3147 46.9822 56.5985 58.8033 95.6251 65.1405 64.0531 72.6078 61.3049
Translational Efficiency 1.5547 1.5095 1.8027 1.8106 1.6421 1.3493 1.374 1.6639 1.4157 1.3737

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✔

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2182 1129 1489 120 1493 1703 207 808 3675 2832 1696 928

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1092.08 1248.56 1331.32 1674.55 1040.60 1247.44 1482.34 1504.85 1071.17 1247.89 1349.75 1526.79
Standard Deviation 141.45 185.52 177.65 246.09 150.65 158.87 176.18 221.78 147.44 170.00 184.23 232.16
Intensity Change Log 2 — 0.193187 0.285779 0.616695 — 0.261555 0.510461 0.532204 — 0.226950 0.399780 0.576087

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001469 0.003082 0.013214 0.018812 0.002143 0.005185 0.042055 0.009345 0.001743 0.004346 0.016734 0.010570
Bud Neck 0.004537 0.005783 0.011144 0.023380 0.006568 0.010682 0.023437 0.010919 0.005363 0.008729 0.012645 0.012530
Bud Site 0.022693 0.065786 0.067013 0.164148 0.049616 0.060889 0.166092 0.085277 0.033630 0.062841 0.079106 0.095476
Cell Periphery 0.310035 0.442922 0.502984 0.275201 0.301444 0.314989 0.329411 0.186826 0.306545 0.365991 0.481799 0.198254
Cytoplasm 0.645404 0.451826 0.357603 0.366931 0.614390 0.570533 0.277694 0.641190 0.632805 0.523210 0.347850 0.605726
Cytoplasmic Foci 0.002302 0.004844 0.001300 0.001287 0.005427 0.008007 0.018616 0.001546 0.003572 0.006746 0.003413 0.001513
Eisosomes 0.000365 0.000223 0.003306 0.001555 0.000524 0.001186 0.004095 0.000471 0.000430 0.000802 0.003403 0.000611
Endoplasmic Reticulum 0.000646 0.004002 0.005779 0.000788 0.004557 0.002705 0.005909 0.000432 0.002235 0.003222 0.005795 0.000478
Endosome 0.000219 0.000914 0.000497 0.001082 0.000647 0.001875 0.002355 0.000437 0.000393 0.001492 0.000724 0.000521
Golgi 0.000602 0.001231 0.000647 0.000536 0.001027 0.002297 0.001855 0.000329 0.000775 0.001872 0.000795 0.000356
Lipid Particles 0.000718 0.001601 0.005057 0.020245 0.000904 0.002045 0.009019 0.006895 0.000794 0.001868 0.005541 0.008622
Mitochondria 0.000351 0.000946 0.000380 0.000243 0.000760 0.000468 0.000018 0.000118 0.000517 0.000659 0.000336 0.000134
Mitotic Spindle 0.000304 0.000227 0.000328 0.000349 0.000176 0.000287 0.000233 0.000204 0.000252 0.000263 0.000316 0.000223
None 0.000039 0.000035 0.000084 0.000029 0.000074 0.000085 0.000016 0.000077 0.000054 0.000065 0.000075 0.000071
Nuclear Periphery 0.000166 0.000199 0.000509 0.000197 0.000145 0.000153 0.000142 0.000128 0.000157 0.000172 0.000464 0.000137
Nuclear Periphery Foci 0.000160 0.000584 0.000720 0.003121 0.000434 0.000440 0.003914 0.000904 0.000271 0.000497 0.001110 0.001191
Nucleolus 0.000034 0.000031 0.000043 0.000076 0.000026 0.000049 0.000011 0.000030 0.000031 0.000042 0.000039 0.000036
Nucleus 0.000558 0.000528 0.003265 0.002165 0.000681 0.001133 0.002962 0.001993 0.000608 0.000892 0.003228 0.002015
Peroxisomes 0.002241 0.001183 0.001348 0.000399 0.001487 0.002354 0.000855 0.000485 0.001935 0.001887 0.001288 0.000474
Vacuole 0.006823 0.013248 0.024314 0.117426 0.008360 0.014017 0.111157 0.051171 0.007447 0.013710 0.034913 0.059738
Vacuole Periphery 0.000333 0.000805 0.000463 0.002027 0.000608 0.000621 0.000155 0.001222 0.000444 0.000694 0.000425 0.001326

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.87 -12.23 -6.70 -6.07 -2.10 -5.15 -8.23 -9.30 -4.43 6.63 -6.78 -14.31 -11.61 -7.55 4.69
Bud Neck -1.73 -9.07 -6.40 -5.91 -4.12 -4.66 -8.85 -5.03 -0.29 6.32 -5.72 -10.88 -9.01 -4.33 0.05
Bud Site -10.04 -11.74 -7.52 -5.15 -5.11 -2.69 -9.12 -6.54 -4.43 5.94 -10.27 -11.93 -12.19 -6.10 -2.88
Cell Periphery -10.73 -18.70 1.71 7.15 10.08 -1.21 -1.03 10.85 12.07 6.35 -7.32 -19.08 12.83 17.75 27.23
Cytoplasm 16.70 28.90 11.74 3.47 -0.29 4.07 20.77 -2.12 -5.86 -21.38 14.10 33.26 2.76 -7.45 -22.35
Cytoplasmic Foci -3.10 3.51 1.77 3.89 -0.37 -2.39 -4.35 4.90 6.83 5.50 -4.69 -0.12 4.28 7.52 3.60
Eisosomes 5.05 -10.99 -4.00 -4.48 4.26 -4.80 -9.37 0.55 6.42 9.74 -4.95 -12.30 -2.88 2.27 11.42
Endoplasmic Reticulum -3.57 -7.57 -0.69 3.39 7.22 2.13 -1.05 5.48 4.81 5.40 -1.78 -5.26 5.33 5.77 8.67
Endosome -3.15 -6.08 -0.99 -0.18 -0.67 -2.92 -3.88 0.96 3.16 4.05 -4.14 -4.45 -0.67 2.93 0.97
Golgi -1.63 -0.21 0.29 1.92 0.70 -3.16 -2.84 4.39 4.90 5.33 -3.71 -0.12 2.62 5.35 3.96
Lipid Particles -3.06 -7.10 -3.85 -3.68 -2.99 -3.03 -6.79 -4.75 -3.74 1.46 -4.11 -8.83 -6.08 -5.21 -2.23
Mitochondria -1.25 -0.26 0.45 1.37 0.62 0.93 2.45 2.10 3.92 -2.68 -0.60 1.25 2.66 2.67 3.35
Mitotic Spindle 0.57 -0.16 -0.18 -0.69 -0.10 -1.29 -1.68 -0.27 0.63 0.52 -0.12 -0.82 0.25 0.39 1.04
None 0.67 -5.75 1.69 0.86 6.86 -0.26 2.49 -0.13 0.19 -4.01 -0.52 -1.94 -1.09 -0.28 0.27
Nuclear Periphery -1.93 -11.59 -0.67 0.09 6.03 -0.59 0.18 1.42 1.75 0.79 -1.30 -11.88 1.84 2.66 12.23
Nuclear Periphery Foci -8.04 -17.58 -6.30 -5.40 -5.13 -0.14 -7.46 -7.13 -5.00 6.48 -4.65 -11.79 -10.83 -7.24 -0.53
Nucleolus 1.72 -4.48 -0.62 -0.67 -0.49 -2.34 9.00 -0.82 1.79 -4.28 -1.87 -4.62 -0.53 0.56 0.31
Nucleus 0.85 -16.00 -5.80 -5.90 2.91 -6.60 -9.03 -8.73 -5.59 3.18 -6.70 -17.30 -10.51 -8.28 5.66
Peroxisomes 2.71 2.27 4.78 7.37 8.52 -4.00 5.20 9.90 9.28 4.44 0.16 2.64 6.28 10.91 8.79
Vacuole -7.21 -17.43 -8.69 -8.18 -7.33 -7.01 -11.23 -15.65 -13.39 6.22 -10.74 -17.29 -17.62 -15.37 -7.62
Vacuole Periphery -3.47 -2.70 -0.91 -0.65 -0.84 -0.13 6.49 -0.80 -0.78 -1.41 -3.21 0.39 -1.25 -0.88 -1.27
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Low complexity protein; mediates inhibition of Mep1p and Mep3p activity; hyperphosphorylated upon rapamycin treatment in a Tap42p-dependent manner; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; phosphorylation and localization regulated by TORC1-effector kinase, Npr1p
Localization
Cell Percentages cell periphery (17%), cytoplasm (11%), mixed (73%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Par32

Par32


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Par32-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available