Standard name
Human Ortholog
Description Chromatin associated high mobility group (HMG) family member; involved in compacting, bending, bridging and looping DNA; rDNA-binding component that regulates transcription from RNA polymerase I promoters; regulates start site selection of ribosomal protein genes via RNA polymerase II promoters; role in genome maintenance; associates with a 5'-3' DNA helicase and Fpr1p, a prolyl isomerase; relocalizes to the cytosol in response to hypoxia
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.11 0.07 0.05 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.37 0.33 0.27 0.25 0.21 0.24 0.22 0.15 0.33 0.2 0.28 0.29 0.25 0.21 0.2 0.07 0.06 0 0 0 0 0 0 0
Nucleus 0.13 0.09 0.06 0 0 0 0 0 0 0 0 0 0.05 0 0 0.05 0 0 0.06 0.13 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.92 0.94 0.95 0.94 0.94 0.92 0.93 0.93 0.91 0.94 0.95 0.94 0.94 0.9 0.84 0.88 0.92 0.95 0.85 0.79 0.88 0.85 0.87 0.79
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0.05 0.07 0.09 0.06 0 0.06 0.05 0.08 0 0 0 0 0 0 0.05 0 0 0.06 0 0.08
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 1 0 0 0 1 6
Bud Neck 0 0 1 3 2 0 6 4 2 2 6 2 2 7 5 0 0 0 0 0 2 0 6 5
Bud Site 3 0 0 0 1 1 4 0 3 1 0 2 0 1 0 0 0 0 – – – – – –
Cell Periphery 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 10 6 10 4 4 8 6 8 2 7 35 66 10 8 3 0 0 0 0 0 2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 2 2 0 0 0 0 0 1
Endosome 0 0 0 0 1 4 1 2 1 0 0 2 0 1 7 1 1 1 2 0 0 2 3 4
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Mitochondria 86 18 47 60 57 75 98 82 143 69 113 139 70 115 120 10 10 3 1 0 0 2 4 7
Nucleus 30 5 11 7 7 6 10 17 10 8 8 13 13 14 13 8 6 5 13 9 6 3 14 5
Nuclear Periphery 1 0 0 0 0 0 0 0 0 0 1 1 0 0 1 0 0 0 0 0 0 0 1 2
Nucleolus 212 51 162 221 259 291 409 514 395 318 386 457 259 497 502 133 144 110 197 56 162 154 416 320
Peroxisomes 1 0 0 0 3 14 6 11 2 5 1 9 3 6 12 2 2 0 0 0 0 0 0 1
SpindlePole 2 0 3 9 14 22 38 32 19 22 21 40 4 21 9 1 2 0 11 2 5 10 19 32
Vac/Vac Membrane 0 0 0 1 0 2 2 5 3 1 2 0 0 3 3 1 0 1 2 0 2 2 5 9
Unique Cell Count 231 54 171 236 276 316 441 555 435 339 407 486 277 550 598 151 156 116 233 71 184 182 481 408
Labelled Cell Count 336 74 224 311 350 425 578 672 586 432 547 667 358 700 738 169 175 125 233 71 184 182 481 408


Nucleolus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 32.7 22.3 31.0 31.4 30.2 25.5 23.9 23.7 24.3 21.4 22.2 22.4 32.0 31.5 29.9 28.2 36.8 44.9 30.7 35.8 32.5
Std Deviation (1e-4) 14.5 10.4 11.9 14.2 12.1 11.3 9.9 8.9 11.7 8.3 9.7 9.6 14.7 14.7 16.0 13.7 18.2 21.7 12.9 15.4 14.4
Intensity Change (Log2) – – – 0.02 -0.04 -0.28 -0.38 -0.39 -0.35 -0.54 -0.48 -0.47 0.04 0.02 -0.06 -0.14 0.25 0.53 -0.02 0.21 0.07


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 3.4 4.5 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -0.5 -1.7 -0.9 -1.4 -3.8 1.3 -1.8 0.1 0.3 -0.5 -1.8 -2.1 -4.9 -5.0 -5.5
Nucleus -1.7 -2.0 -2.6 -2.5 -2.0 -2.5 -2.3 -2.7 -2.3 -0.8 -2.4 -2.8 -0.4 -1.1 -0.8
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus -0.5 -0.4 -1.1 -0.9 -1.0 -1.6 -0.4 0.1 -0.3 -0.5 -1.8 -3.6 -2.2 -0.9 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 1.2 1.8 2.5 3.0 2.1 1.5 2.3 1.9 2.9 0 1.3 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 49.5975 36.7066 37.5399 36.1626 29.3849 35.5295 54.4762 37.2504 40.2383 44.0627 38.127 38.508 60.0207 42.3803 44.4236 41.8563 42.2533 41.0286
Actin 0.0196 0 0.0043 0.0021 0.0027 0 0.0029 0 0.0023 0 0.0042 0.004 0.0079 0 0.0068 0 0.0018 0
Bud 0.0003 0 0.0003 0 0.0002 0 0 0 0 0 0 0 0.0001 0 0 0 0.0001 0
Bud Neck 0.0009 0 0.0002 0 0.0002 0.0001 0.0001 0.0001 0.0001 0 0.0001 0 0.0013 0 0.0001 0 0.0001 0
Bud Periphery 0.0005 0 0.0003 0 0.0006 0 0 0 0 0 0.0001 0.0001 0.0001 0 0 0 0.0001 0
Bud Site 0.001 0 0.0038 0.0001 0.001 0 0.0001 0.0002 0.0002 0 0.0002 0.0001 0.0018 0.0001 0 0 0.0002 0
Cell Periphery 0.0003 0.0001 0.0003 0 0.0002 0.0001 0.0002 0.0001 0.0002 0.0002 0.0003 0.0001 0.0003 0.0001 0.0001 0.0001 0.0003 0.0001
Cytoplasm 0.0005 0 0.0014 0 0.0001 0.0001 0.0015 0 0.0015 0 0.0001 0.0001 0.0008 0 0 0 0.0001 0
Cytoplasmic Foci 0.0163 0.0011 0.0115 0.0036 0.0098 0.0146 0.0139 0.01 0.0029 0.0032 0.0206 0.0014 0.0091 0.0003 0.0008 0.0003 0.0023 0.0012
Eisosomes 0.0002 0 0.0006 0 0.0002 0 0.0002 0 0.0001 0 0.0003 0 0.0002 0 0.0001 0 0.0002 0
Endoplasmic Reticulum 0.0007 0 0.0008 0 0.0001 0 0.0003 0 0.0003 0 0 0 0.0003 0 0 0 0.0009 0
Endosome 0.0246 0 0.0039 0.0007 0.0055 0 0.0016 0 0.0021 0 0.0014 0.0003 0.0017 0 0.0001 0 0.01 0
Golgi 0.0139 0 0.002 0.0015 0.0053 0 0.0011 0 0.0013 0 0.0024 0.0004 0.0006 0 0.0002 0 0.0024 0
Lipid Particles 0.0125 0.0005 0.0108 0.0171 0.0312 0.0061 0.0076 0.0017 0.0043 0.0011 0.022 0.0024 0.0042 0.0003 0.0007 0.0003 0.0111 0.004
Mitochondria 0.011 0.0007 0.0069 0.0011 0.0818 0.0087 0.0061 0.0002 0.0018 0.0018 0.0541 0.0065 0.0076 0.0008 0.0023 0.0004 0.0544 0.0011
None 0.0008 0 0.0047 0.0001 0.0002 0.0005 0.0045 0 0.0131 0 0.0003 0 0.0011 0 0 0 0.0004 0
Nuclear Periphery 0.0036 0 0.002 0 0.0005 0 0.0007 0.0001 0.0006 0 0.0002 0 0.0003 0 0 0 0.008 0
Nucleolus 0.842 0.9415 0.8982 0.9225 0.8088 0.9351 0.9213 0.926 0.9357 0.9623 0.8533 0.9472 0.923 0.9384 0.9494 0.941 0.8687 0.9538
Nucleus 0.0254 0.0457 0.0426 0.0305 0.0255 0.0318 0.0267 0.0527 0.0303 0.0298 0.0229 0.0337 0.0318 0.0596 0.0382 0.0547 0.0317 0.0388
Peroxisomes 0.0072 0 0.0019 0.0198 0.0138 0.0008 0.0089 0.0001 0.001 0.0002 0.0115 0.0002 0.0041 0 0.0002 0 0.002 0.0001
Punctate Nuclear 0.0054 0.0099 0.0018 0.0007 0.0103 0.0017 0.0017 0.0087 0.002 0.0011 0.0042 0.0032 0.0028 0.0001 0.0004 0.003 0.0014 0.0006
Vacuole 0.0089 0.0001 0.0007 0.0001 0.0009 0.0002 0.0002 0.0001 0.0003 0.0002 0.0003 0.0001 0.0004 0.0001 0.0001 0.0001 0.0009 0.0001
Vacuole Periphery 0.0045 0.0001 0.0012 0 0.0011 0.0003 0.0004 0 0.0002 0.0002 0.0014 0.0001 0.0005 0.0001 0.0002 0 0.0029 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 93.8117 89.1865 131.3727 85.9538 111.9777 132.4543 95.2236 105.8289 114.5142 99.8291
Translational Efficiency 0.7007 0.6534 0.6713 1.251 0.746 0.8449 0.768 0.862 1.0298 1.3503

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1926 1547 2291 1492 1855 1412 311 1579 3781 2959 2602 3071

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1705.74 2117.78 2731.39 2341.77 1910.25 2313.57 2668.83 2585.29 1806.07 2211.21 2723.91 2466.98
Standard Deviation 593.58 824.76 855.74 805.38 700.00 830.82 738.24 852.70 656.00 833.41 842.80 838.92
Intensity Change Log 2 — 0.312155 0.679238 0.457202 — 0.276359 0.482446 0.436565 — 0.293356 0.578627 0.446336

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000284 0.000293 0.000490 0.000654 0.000219 0.000286 0.000355 0.000591 0.000252 0.000289 0.000474 0.000622
Bud Neck 0.000958 0.000817 0.001979 0.007525 0.000625 0.000830 0.003131 0.003752 0.000795 0.000823 0.002117 0.005586
Bud Site 0.000431 0.000558 0.000507 0.003060 0.000584 0.000407 0.000987 0.001552 0.000506 0.000486 0.000565 0.002285
Cell Periphery 0.000044 0.000043 0.000027 0.000203 0.000023 0.000033 0.000027 0.000085 0.000034 0.000038 0.000027 0.000143
Cytoplasm 0.000605 0.000634 0.000115 0.001979 0.000881 0.000444 0.000116 0.000874 0.000741 0.000544 0.000115 0.001411
Cytoplasmic Foci 0.012547 0.023216 0.003727 0.022441 0.018271 0.014110 0.013309 0.010296 0.015355 0.018871 0.004872 0.016197
Eisosomes 0.000266 0.000523 0.000271 0.000197 0.000432 0.000379 0.000216 0.000234 0.000348 0.000454 0.000265 0.000216
Endoplasmic Reticulum 0.000120 0.000079 0.000078 0.000207 0.000072 0.000135 0.000078 0.000109 0.000096 0.000106 0.000078 0.000157
Endosome 0.000023 0.000019 0.000014 0.002346 0.000012 0.000122 0.000017 0.000500 0.000018 0.000068 0.000015 0.001397
Golgi 0.000188 0.000158 0.000218 0.002212 0.000136 0.000239 0.000344 0.001118 0.000163 0.000197 0.000233 0.001649
Lipid Particles 0.000026 0.000035 0.000007 0.000299 0.000022 0.000238 0.000011 0.000037 0.000024 0.000131 0.000007 0.000164
Mitochondria 0.000912 0.001994 0.001822 0.004063 0.000972 0.001193 0.001511 0.002564 0.000941 0.001612 0.001785 0.003293
Mitotic Spindle 0.007193 0.004254 0.020872 0.037352 0.006366 0.006163 0.018656 0.013219 0.006787 0.005165 0.020607 0.024943
None 0.000680 0.000854 0.000402 0.001408 0.000581 0.000654 0.000633 0.001317 0.000631 0.000759 0.000430 0.001361
Nuclear Periphery 0.000168 0.000051 0.000187 0.001062 0.000048 0.000061 0.000115 0.000267 0.000109 0.000056 0.000179 0.000654
Nuclear Periphery Foci 0.000152 0.000080 0.000062 0.000673 0.000102 0.000220 0.000045 0.000186 0.000128 0.000147 0.000060 0.000422
Nucleolus 0.571082* 0.479819* 0.606425* 0.584197* 0.444982* 0.507713* 0.537057* 0.582393* 0.509216* 0.493130* 0.598134* 0.583270*
Nucleus 0.152431* 0.129435 0.192801* 0.204117* 0.102745 0.134541* 0.151893* 0.231917* 0.128054 0.131871* 0.187912* 0.218411*
Peroxisomes 0.251367* 0.355736* 0.169245* 0.117004* 0.422256* 0.331517* 0.270663* 0.145428* 0.335207* 0.344179* 0.181367* 0.131618*
Vacuole 0.000209 0.000783 0.000177 0.005260 0.000325 0.000318 0.000307 0.001903 0.000266 0.000561 0.000192 0.003534
Vacuole Periphery 0.000314 0.000617 0.000573 0.003740 0.000346 0.000397 0.000530 0.001656 0.000330 0.000512 0.000567 0.002669

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.20 -10.72 -12.12 -12.18 -5.84 -2.14 -4.24 -4.98 -4.08 -3.01 -1.91 -13.44 -9.10 -8.21 -3.83
Bud Neck 2.04 -7.69 -10.39 -10.59 -8.92 -3.69 -5.84 -9.87 -9.24 -1.77 -0.58 -10.72 -13.54 -13.48 -9.92
Bud Site -0.98 -1.32 -8.64 -8.31 -8.49 1.02 -2.19 -3.02 -4.06 -2.03 0.38 -0.82 -8.32 -8.90 -8.53
Cell Periphery 0.15 1.58 -7.08 -6.72 -8.18 -0.92 -0.56 -4.61 -3.44 -4.73 -0.40 0.83 -8.34 -7.44 -9.41
Cytoplasm 0.19 1.54 -2.26 -2.74 -4.96 0.69 1.59 -0.09 -0.95 -2.20 0.58 2.20 -1.69 -2.66 -5.17
Cytoplasmic Foci -5.13 8.13 -5.50 -0.99 -10.02 2.16 1.86 4.40 1.66 1.42 -2.50 11.64 -2.07 0.31 -10.45
Eisosomes -5.05 -0.34 4.25 6.31 4.56 2.02 9.89 9.25 5.83 -0.70 -3.61 6.92 9.74 8.06 3.99
Endoplasmic Reticulum 1.69 1.80 -2.41 -3.86 -3.98 -1.68 -1.25 -3.21 0.73 -2.38 -0.63 1.38 -3.21 -1.86 -4.65
Endosome 0.73 1.88 -4.32 -4.33 -4.34 -1.21 -2.41 -2.51 -1.72 -2.47 -1.16 0.99 -4.94 -4.67 -4.95
Golgi 1.52 -3.02 -3.84 -3.90 -3.77 -1.95 -11.63 -1.99 -1.74 -1.53 -1.34 -10.14 -4.09 -3.96 -3.86
Lipid Particles -0.38 1.54 -2.72 -2.68 -2.97 -1.53 3.25 -1.68 1.40 -2.67 -1.57 2.44 -2.90 -0.28 -3.31
Mitochondria -2.76 -9.79 -12.92 -4.96 -9.00 -2.18 -3.66 -8.73 -7.09 -4.48 -3.19 -10.65 -15.51 -7.04 -9.24
Mitotic Spindle 3.62 -8.87 -9.94 -11.06 -4.99 -0.04 -3.20 -4.26 -4.02 1.17 2.23 -9.98 -10.62 -11.47 -2.10
None -1.54 4.15 -3.19 -2.36 -4.34 -0.64 -0.37 -3.54 -3.15 -2.65 -1.54 2.98 -4.74 -3.79 -6.14
Nuclear Periphery 2.11 -0.48 -4.29 -4.96 -4.29 -1.83 -3.75 -8.53 -8.04 -5.06 1.86 -2.49 -5.29 -5.97 -4.72
Nuclear Periphery Foci 1.91 2.42 -3.24 -3.78 -3.90 -1.59 3.61 -1.65 -0.24 -2.21 -0.63 3.28 -3.59 -3.07 -4.39
Nucleolus 12.24 -5.18 0.16 -9.65 4.13 -8.28 -6.93 -16.26 -8.16 -3.28 2.96 -15.76 -10.58 -12.76 3.53
Nucleus 3.94 -6.85 -7.70 -10.77 -2.35 -5.58 -4.22 -17.75 -12.33 -6.28 -0.97 -12.40 -17.71 -16.45 -5.64
Peroxisomes -13.74 14.66 23.86 35.07* 11.70 11.18 11.55 40.65* 26.80 10.36 -1.53 30.49 43.92* 43.51* 12.47
Vacuole -3.69 2.23 -4.89 -4.31 -4.93 -0.03 0.22 -2.54 -2.54 -2.56 -3.48 3.19 -5.48 -4.96 -5.60
Vacuole Periphery -4.72 -11.77 -6.04 -5.46 -5.57 -0.81 -2.48 -4.02 -3.93 -3.50 -3.95 -6.91 -7.25 -6.67 -6.52
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Chromatin associated high mobility group (HMG) family member; involved in compacting, bending, bridging and looping DNA; rDNA-binding component that regulates transcription from RNA polymerase I promoters; regulates start site selection of ribosomal protein genes via RNA polymerase II promoters; role in genome maintenance; associates with a 5'-3' DNA helicase and Fpr1p, a prolyl isomerase; relocalizes to the cytosol in response to hypoxia
Localization
Cell Percentages nucleolus (93%)
Cell Cycle Regulation No
Subcompartmental Group nucleolus-2

Hmo1

Hmo1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Hmo1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available