Standard name
Human Ortholog
Description Nuclear protein; possibly involved in regulation of cation stress responses and/or in the establishment of bipolar budding pattern; relative distribution to the nucleus decreases upon DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Cytoplasm 0.47 0.38 0.53 0.76 0.98 0.95 0.93 0.93 0.76 0.81 0.73 0.77 0.79 1.0 1.0 – – 0.54 0.25 0.29 0.25 0.23 0.81 0.74
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Endosome 0 0 0.05 0.05 0 0 0 0 0 0 0 0 0.07 0 0 – – 0.11 0.08 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Mitochondria 0.12 0.52 0 0.1 0 0.05 0.1 0.07 0.34 0.23 0.37 0.33 0 0 0 – – 0.08 0.11 0.07 0.11 0 0 0
Nucleus 0.12 0.11 0.23 0 0 0 0 0 0 0 0 0 0 0 0 – – 0.16 0.17 0.18 0.18 0.26 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
SpindlePole 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0.11 0.13 0.12 0.18 0.05 0.07
Vac/Vac Membrane 0.35 0.13 0.09 0.1 0 0 0 0 0 0 0 0 0 0 0 – – 0.21 0.17 0.19 0.16 0.14 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 3 0 0 0 2
Bud 0 0 1 0 0 2 0 1 0 2 5 3 0 0 0 – – 0 1 8 2 2 4 9
Bud Neck 0 1 4 1 4 9 3 14 3 12 7 6 1 0 1 – – 0 1 3 0 3 0 2
Bud Site 0 0 0 0 0 0 0 0 0 0 2 2 0 0 0 – – 0 – – – – – –
Cell Periphery 0 1 0 0 2 1 2 0 0 1 0 0 0 0 0 – – 0 0 0 0 0 0 0
Cytoplasm 8 81 52 76 199 278 342 380 210 242 273 291 22 269 250 – – 79 28 82 50 34 235 213
Endoplasmic Reticulum 0 3 2 0 0 0 1 0 0 0 1 0 0 0 0 – – 5 0 1 1 0 0 0
Endosome 0 0 5 5 0 0 0 1 0 0 1 0 2 0 0 – – 16 9 8 5 5 4 4
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 – – 2 0 1 0 0 2 0
Mitochondria 2 110 3 10 1 14 38 27 94 67 140 124 1 0 1 – – 11 12 19 22 4 6 6
Nucleus 2 24 23 3 1 4 4 0 1 1 2 2 1 0 0 – – 24 19 50 37 40 2 7
Nuclear Periphery 0 1 0 0 0 0 0 0 2 0 0 0 0 0 0 – – 0 0 0 1 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 1 4 4 5 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 1 0 0 0 0 0 0
SpindlePole 0 6 6 1 2 0 3 7 1 6 3 14 1 0 0 – – 5 12 36 25 27 13 20
Vac/Vac Membrane 6 27 9 10 4 1 1 3 5 4 3 2 0 4 0 – – 31 18 53 33 22 11 9
Unique Cell Count 17 213 98 100 204 292 366 409 276 297 376 379 28 270 251 146 113 287 206 154 291 290
Labelled Cell Count 18 254 105 106 213 309 394 433 316 335 437 444 28 273 253 174 113 287 206 154 291 290


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.2 3.3 5.1 4.7 4.8 4.0 3.9 4.0 3.2 3.5 3.3 3.4 4.6 4.5 4.4 4.1 4.9 5.3 5.4 5.1 5.3
Std Deviation (1e-4) 0.4 0.5 1.3 1.9 1.4 1.7 1.4 1.0 1.2 1.0 1.0 0.9 0.7 1.0 1.2 1.2 1.7 1.8 1.8 1.6 1.9
Intensity Change (Log2) – – – -0.1 -0.08 -0.34 -0.36 -0.33 -0.67 -0.53 -0.6 -0.59 -0.14 -0.18 -0.21 -0.32 -0.06 0.06 0.1 0.02 0.05


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – 0
Bud Neck – – – – – – – – – – – – – – 0
Bud Site – – – – – – – – – – – – – – 0
Cell Periphery – – – – – – – – – – – – – – 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – 0
Endosome – – – – – – – – – – – – – – 0
Golgi – – – – – – – – – – – – – – 0
Mitochondria – – – – – – – – – – – – – – 0
Nuclear Periphery – – – – – – – – – – – – – – 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – 0
Peroxisomes – – – – – – – – – – – – – – 0
SpindlePole – – – – – – – – – – – – – – 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – 0
Cytoplasm – – – – – – – – – – – – – – 0
Nucleus – – – – – – – – – – – – – – 0
Vacuole – – – – – – – – – – – – – – 2.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.5597 3.0939 3.5211 2.7424 2.7973 3.2307 1.7164 1.7271 1.6402 1.5455 1.654 1.5828 -1.3332 -0.9668 -1.199 -1.2311 -1.0509 -1.3406
Actin 0.0623 0.0016 0.0186 0.0012 0.0098 0.0019 0.0256 0.0004 0.009 0.0132 0.0122 0.0099 0.0286 0.0014 0.0095 0.0003 0.0042 0.007
Bud 0.001 0.0005 0.0005 0.0001 0.0003 0.0006 0.0009 0.0001 0.0034 0.0016 0.0009 0.0002 0.0007 0.0004 0.0002 0.0001 0.0002 0.0011
Bud Neck 0.0126 0.0013 0.0009 0.0005 0.0018 0.0074 0.0083 0.0005 0.0008 0.0024 0.001 0.0027 0.0015 0.0024 0.0062 0.001 0.0008 0.0031
Bud Periphery 0.0017 0.0004 0.0011 0.0006 0.0006 0.0051 0.0015 0.0001 0.0069 0.004 0.001 0.0005 0.0009 0.0002 0.0002 0.0001 0.0002 0.0024
Bud Site 0.0153 0.0088 0.0072 0.0001 0.0015 0.0003 0.0105 0.0028 0.0016 0.0098 0.0094 0.0003 0.0025 0.0049 0.0043 0.0002 0.0004 0.0005
Cell Periphery 0.0006 0.0002 0.001 0.0001 0.0006 0.0002 0.0003 0.0001 0.0002 0.0018 0.0003 0.0001 0.0002 0.0001 0.0001 0 0.0001 0.0001
Cytoplasm 0.1701 0.2565 0.1547 0.2276 0.1677 0.219 0.0712 0.2181 0.1673 0.1225 0.1683 0.2019 0.2141 0.2558 0.2056 0.1971 0.2062 0.2932
Cytoplasmic Foci 0.0539 0.0149 0.0147 0.007 0.0203 0.0166 0.049 0.0057 0.0066 0.06 0.0232 0.0125 0.0364 0.0132 0.018 0.0087 0.0109 0.0102
Eisosomes 0.0005 0.0002 0.0007 0.0002 0.0006 0.0001 0.0006 0.0002 0.0003 0.0002 0.0003 0.0003 0.0003 0.0001 0.0002 0 0.0001 0.0002
Endoplasmic Reticulum 0.0109 0.0036 0.0076 0.0035 0.0039 0.0033 0.0059 0.0037 0.0102 0.0016 0.0026 0.0079 0.0092 0.0073 0.0065 0.003 0.0094 0.0035
Endosome 0.0335 0.0025 0.0119 0.0036 0.0246 0.0048 0.0354 0.004 0.0102 0.025 0.025 0.0087 0.0231 0.0076 0.0078 0.0046 0.0312 0.0057
Golgi 0.0148 0.0004 0.0053 0.0001 0.0272 0.0004 0.0075 0.0002 0.0019 0.0046 0.0181 0.0136 0.0062 0.0003 0.0019 0.0001 0.008 0.0012
Lipid Particles 0.0245 0.0015 0.0063 0.0004 0.0477 0.001 0.0245 0.0008 0.0016 0.0103 0.004 0.0026 0.0163 0.0023 0.003 0.0002 0.0105 0.0012
Mitochondria 0.0063 0.0065 0.0251 0.0013 0.0081 0.0017 0.0194 0.0005 0.0191 0.0061 0.0988 0.0418 0.0044 0.0006 0.0011 0.001 0.0008 0.002
None 0.3443 0.3607 0.4068 0.456 0.4453 0.3858 0.5857 0.5272 0.4367 0.564 0.4702 0.3362 0.3877 0.4177 0.343 0.3014 0.4983 0.2699
Nuclear Periphery 0.0213 0.0088 0.0253 0.017 0.0184 0.0088 0.0308 0.0077 0.0094 0.0028 0.0082 0.0076 0.0326 0.0189 0.0269 0.0137 0.0183 0.0105
Nucleolus 0.0033 0.0066 0.0044 0.0024 0.0028 0.006 0.004 0.0031 0.0034 0.0027 0.0012 0.0036 0.0032 0.0031 0.0031 0.0027 0.0015 0.0049
Nucleus 0.1339 0.2808 0.249 0.2083 0.1714 0.2801 0.0387 0.1641 0.2615 0.0363 0.1046 0.276 0.1719 0.1991 0.289 0.3991 0.1842 0.3222
Peroxisomes 0.0299 0.0033 0.0025 0.0002 0.0072 0.0004 0.0214 0.0003 0.0008 0.0494 0.0128 0.0197 0.0116 0.0004 0.0076 0.0001 0.0025 0.0012
Punctate Nuclear 0.0524 0.039 0.0521 0.0687 0.0362 0.0533 0.0475 0.0584 0.0469 0.04 0.0354 0.0516 0.0429 0.0617 0.0629 0.064 0.0069 0.0577
Vacuole 0.0054 0.0017 0.0029 0.0007 0.0025 0.0024 0.0072 0.0017 0.0017 0.037 0.0017 0.0018 0.0041 0.0022 0.0024 0.002 0.0043 0.0018
Vacuole Periphery 0.0014 0.0002 0.0014 0.0003 0.0014 0.0007 0.004 0.0002 0.0005 0.0046 0.0008 0.0006 0.0017 0.0004 0.0006 0.0005 0.001 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 32.4164 20.0619 18.195 23.2986 20.2064 13.707 15.2134 21.2967 10.7197 23.1336
Translational Efficiency 1.4632 1.5818 1.8619 0.9216 1.563 2.3916 1.3864 0.5548 1.4157 1.3786

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1335 112 2367 387 1107 2125 203 1294 2442 2237 2570 1681

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 656.51 808.52 797.73 901.84 584.29 780.39 894.16 895.47 623.77 781.80 805.35 896.94
Standard Deviation 67.44 98.01 87.15 109.36 69.68 89.43 93.82 113.66 77.33 90.09 91.47 112.72
Intensity Change Log 2 — 0.300466 0.281084 0.458055 — 0.417511 0.613848 0.615961 — 0.356767 0.447365 0.534569

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000069 0.001336 0.000280 0.003000 0.000060 0.000137 0.000856 0.001581 0.000065 0.000197 0.000326 0.001908
Bud Neck 0.006181 0.007274 0.014667 0.013065 0.002601 0.010270 0.002665 0.014932 0.004558 0.010120 0.013719 0.014502
Bud Site 0.001225 0.008754 0.010937 0.021288 0.000824 0.004075 0.002615 0.010968 0.001043 0.004309 0.010280 0.013344
Cell Periphery 0.000111 0.000373 0.000146 0.000232 0.000129 0.000156 0.000220 0.000153 0.000119 0.000166 0.000151 0.000172
Cytoplasm 0.356589* 0.155440* 0.157984* 0.089035 0.463855* 0.242130* 0.085346 0.093067 0.405214* 0.237790* 0.152246* 0.092139
Cytoplasmic Foci 0.129633 0.149503 0.002101 0.006939 0.094735 0.066748 0.007193 0.005408 0.113813 0.070891 0.002503 0.005761
Eisosomes 0.000080 0.000178 0.000023 0.000059 0.000060 0.000058 0.000109 0.000041 0.000071 0.000064 0.000030 0.000045
Endoplasmic Reticulum 0.001228 0.006181 0.002765 0.012222 0.000924 0.001390 0.009288 0.008972 0.001090 0.001630 0.003280 0.009720
Endosome 0.003467 0.015229 0.001210 0.004196 0.003033 0.003103 0.002989 0.004448 0.003270 0.003710 0.001350 0.004390
Golgi 0.000628 0.007247 0.000093 0.002563 0.000402 0.000646 0.000139 0.004548 0.000526 0.000976 0.000096 0.004091
Lipid Particles 0.014765 0.023669 0.000653 0.002846 0.006863 0.010149 0.003930 0.002319 0.011183 0.010826 0.000912 0.002440
Mitochondria 0.007738 0.006945 0.002459 0.004723 0.001560 0.009461 0.000639 0.006392 0.004938 0.009335 0.002316 0.006008
Mitotic Spindle 0.002966 0.014193 0.009619 0.037673 0.000263 0.005624 0.001127 0.016316 0.001741 0.006053 0.008948 0.021233
None 0.007583 0.007821 0.006023 0.023392 0.023278 0.012462 0.007597 0.007852 0.014698 0.012230 0.006148 0.011430
Nuclear Periphery 0.001756 0.001755 0.002546 0.003925 0.001029 0.003171 0.002180 0.004169 0.001427 0.003100 0.002517 0.004113
Nuclear Periphery Foci 0.000971 0.004293 0.000545 0.004069 0.001342 0.001009 0.003389 0.001918 0.001139 0.001173 0.000770 0.002414
Nucleolus 0.003263 0.011212 0.001811 0.005600 0.004175 0.009104 0.004418 0.003089 0.003676 0.009209 0.002017 0.003667
Nucleus 0.444931* 0.528771* 0.773354* 0.708296* 0.381447* 0.607666* 0.823588* 0.782213* 0.416152* 0.603716* 0.777322* 0.765196*
Peroxisomes 0.005907 0.021390 0.000203 0.003926 0.001634 0.004870 0.000641 0.000555 0.003970 0.005698 0.000238 0.001331
Vacuole 0.010387 0.026533 0.012204 0.052568 0.011404 0.006837 0.040823 0.028796 0.010848 0.007823 0.014465 0.034269
Vacuole Periphery 0.000518 0.001903 0.000376 0.000383 0.000382 0.000935 0.000248 0.002261 0.000456 0.000983 0.000365 0.001828

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.51 -10.78 -5.52 -0.98 -4.81 -4.22 -8.18 -9.43 -8.81 0.06 -5.81 -13.48 -10.76 -9.53 -8.07
Bud Neck -0.80 -5.57 -5.48 -3.98 -0.13 -7.70 -3.47 -13.33 -5.68 -10.84 -5.18 -7.75 -12.10 -5.93 -2.99
Bud Site -2.92 -6.66 -4.32 -0.44 -1.07 -4.15 -3.97 -7.34 -3.69 -3.47 -4.29 -7.23 -8.26 -4.24 -0.57
Cell Periphery -4.65 -1.64 -5.91 3.02 -3.85 -1.71 -5.43 -1.41 0.71 4.87 -3.50 -2.07 -4.82 0.57 -1.09
Cytoplasm 10.86 27.08 31.33 4.34 9.42 22.59 31.90 42.90 26.60 0.51 22.68 40.80 52.69 27.82 12.89
Cytoplasmic Foci -0.93 27.69 26.82 8.68 -1.07 5.54 20.72 23.20 24.24 3.36 9.84 35.78 35.49 25.53 0.07
Eisosomes -4.86 15.47 -1.78 4.31 -11.38 0.52 -6.86 0.55 0.09 6.99 1.68 11.98 1.57 -0.10 -9.22
Endoplasmic Reticulum -6.51 -9.52 -14.20 -7.82 -11.90 -3.32 -11.45 -23.63 -22.20 2.00 -3.25 -16.10 -26.53 -25.32 -17.88
Endosome -3.20 5.07 -0.28 3.15 -5.27 0.32 -2.08 1.52 1.05 2.97 -0.53 6.55 1.46 1.70 -3.95
Golgi -1.49 8.03 -0.16 1.47 -1.39 -2.11 3.03 -1.55 -1.15 -1.97 -1.86 8.73 -1.40 -0.47 -2.40
Lipid Particles -1.45 12.68 10.68 3.64 -5.26 -4.15 1.68 8.86 12.68 5.26 0.11 15.14 13.78 12.94 -2.99
Mitochondria 0.56 4.06 3.56 2.28 -1.08 -9.25 3.81 -4.07 5.33 -5.48 -4.02 3.60 1.40 6.04 -3.02
Mitotic Spindle -2.05 -4.31 -5.09 -1.58 -3.89 -4.95 -1.93 -8.58 -6.14 -6.36 -3.68 -5.82 -9.40 -7.21 -5.76
None -0.24 2.74 -1.62 -1.22 -2.54 4.26 7.19 7.72 6.07 -0.27 1.44 8.15 6.14 4.63 -2.19
Nuclear Periphery -0.18 -5.30 -6.50 -6.27 -4.68 -5.52 -6.49 -11.45 -6.62 -6.65 -5.06 -8.63 -12.92 -7.77 -8.52
Nuclear Periphery Foci -2.83 1.45 -4.60 -0.39 -5.05 1.42 -3.45 -2.17 -3.65 2.48 0.06 1.04 -5.00 -4.94 -5.80
Nucleolus -3.25 2.78 0.18 3.24 -1.76 -5.02 0.70 1.28 7.68 0.23 -7.68 3.90 0.64 8.44 -3.68
Nucleus -2.24 -36.82 -13.87 -4.59 6.53 -20.88 -19.81 -35.28 -17.00 -0.65 -21.19 -49.00 -38.08 -16.20 4.11
Peroxisomes -3.23 7.30 4.82 4.17 -2.09 -7.12 4.20 6.42 11.89 3.76 -2.81 8.59 7.57 11.25 -2.38
Vacuole -4.04 -5.46 -10.51 -8.31 -9.80 5.15 -7.28 -12.80 -14.13 2.96 4.04 -8.52 -16.51 -17.28 -12.41
Vacuole Periphery -3.62 2.22 2.56 4.40 0.38 -2.42 1.51 -1.72 0.30 -2.04 -2.35 2.39 -1.18 0.95 -1.98
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Nuclear protein; possibly involved in regulation of cation stress responses and/or in the establishment of bipolar budding pattern; relative distribution to the nucleus decreases upon DNA replication stress
Localization
Cell Percentages nucleus (37%), cytoplasm (14%), mixed (36%)
Cell Cycle Regulation Yes
cytoplasm - MA (9.2e-05)
Subcompartmental Group N/A

Atc1

Atc1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Atc1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available