Standard name
Human Ortholog
Description Subunit of RAVE complex (Rav1p, Rav2p, Skp1p); the RAVE complex associates with the V1 domain of the vacuolar membrane (H+)-ATPase (V-ATPase) and promotes assembly and reassembly of the holoenzyme
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0.05 0 0.05 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm 0.73 0.84 0.75 0.87 0.83 0.83 0.69 0.65 0.68 0.71 0.68 0.67 0.88 0.79 0.71 – 0.81 0.78 0.22 0.35 0.25 0.19 0.14 0.15
Endoplasmic Reticulum 0.06 0.06 0 0 0 0 0 0 0 0 0 0 0.06 0 0 – 0.14 0 0 0 0 0.05 0.05 0.06
Endosome 0.1 0 0.09 0.05 0 0 0 0 0 0 0 0 0 0.08 0.12 – 0.1 0 0.23 0.16 0.23 0.11 0.16 0.13
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 0 0 0.16 0.17 0.26 0.32 0.49 0.43 0.53 0.38 0.49 0.55 0 0 0 – 0 0 0.07 0.05 0.15 0.14 0.11 0.11
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.15 0.08 0.06 0 0.06 0 0.05 0 0 0.06 0 0 0.05 0.17 0.24 – 0.14 0.22 0.38 0.36 0.28 0.45 0.49 0.49
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 2 4 0 0 0 0 0 1 3 2 3 0 1 4 4 – 0 0 1 2 4 1 2 2
Bud 0 1 3 5 11 17 24 34 33 26 35 35 2 1 2 – 0 0 2 1 0 0 0 1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 – 0 0 1 1 0 1 1 1
Bud Site 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 – 0 0 – – – – – –
Cell Periphery 0 1 0 0 2 0 1 0 6 7 6 12 0 0 1 – 0 0 0 0 0 0 0 0
Cytoplasm 173 169 192 303 408 513 562 555 469 618 435 576 218 376 367 – 17 14 58 77 76 45 49 56
Endoplasmic Reticulum 15 13 6 1 1 2 4 9 1 7 8 8 15 13 3 – 3 0 8 4 10 11 16 21
Endosome 23 5 22 19 13 6 11 19 9 18 5 4 4 36 60 – 2 0 61 36 70 25 55 46
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 – 0 0 7 2 2 5 6 7
Mitochondria 5 0 41 60 126 195 401 371 362 328 313 477 0 1 0 – 0 0 20 10 48 34 39 39
Nucleus 1 0 1 0 0 7 7 16 4 3 3 0 4 2 1 – 0 0 0 1 0 1 0 1
Nuclear Periphery 1 0 0 0 1 1 10 3 1 1 1 1 0 0 0 – 0 0 1 0 3 0 1 1
Nucleolus 0 0 0 0 0 0 1 4 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1
Peroxisomes 0 0 1 1 1 0 0 1 1 1 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 1 0 2 2 2 1 3 2 0 7 2 2 0 2 5 – 0 0 2 0 3 0 2 1
Vac/Vac Membrane 36 16 16 8 31 23 37 35 29 50 25 23 12 82 126 – 3 4 102 80 86 107 172 181
Unique Cell Count 237 201 257 350 494 619 813 855 689 867 643 865 248 477 519 21 18 270 223 313 240 351 368
Labelled Cell Count 257 209 284 399 596 766 1061 1050 919 1068 836 1138 258 517 570 25 18 270 223 313 240 351 368


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.3 6.7 4.7 4.6 4.3 4.5 4.1 4.4 4.1 4.4 4.1 4.2 6.5 6.8 7.0 – 8.3 8.1 7.4 7.2 7.6
Std Deviation (1e-4) 0.9 1.0 0.8 1.2 1.2 1.2 1.2 1.2 1.0 1.2 1.1 0.9 0.8 1.1 1.0 – 1.6 1.4 1.6 1.2 1.4
Intensity Change (Log2) – – – -0.02 -0.12 -0.05 -0.19 -0.07 -0.19 -0.07 -0.17 -0.15 0.47 0.55 0.6 – 0.83 0.79 0.67 0.63 0.7


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Cytoplasm 3.7 2.6 2.8 -1.7 -2.9 -2.0 -1.1 -2.1 -2.5 3.8 1.3 -1.2 – 0.6 0.3
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 2.1 0.3 0 – 0 0
Endosome 0 0 0 0 0 0 0 0 0 -3.5 -0.5 1.3 – 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 -6.6 -8.8 -9.3 – 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Vacuole -2.5 0 -1.6 -1.1 -1.4 -1.3 -0.3 -1.5 -2.7 -0.7 4.2 6.1 – 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.8683 1.2628 1.1446 0.3427 0.8781 1.1624 2.0795 2.9805 2.2617 2.1559 2.4278 2.3666 0.2675 0.5325 0.3617 0.5408 0.0787 0.3353
Actin 0.0208 0.0009 0.0114 0 0.0039 0.0003 0.0085 0.0002 0.0064 0.0001 0 0.0002 0.0012 0.0001 0.0001 0 0.0001 0.004
Bud 0.0014 0.0059 0.0236 0.0002 0.006 0.0008 0.0003 0.0006 0.0005 0.0021 0.0003 0.0002 0.0003 0.0002 0.0003 0.0003 0.0002 0.0005
Bud Neck 0.0011 0.0003 0.0019 0.0002 0.002 0.0018 0.0004 0.0002 0.0006 0.0003 0.0002 0.0013 0.0005 0.0002 0.0003 0.0005 0.0002 0.0009
Bud Periphery 0.0017 0.0015 0.0062 0.0001 0.0032 0.0009 0.0002 0.0002 0.0005 0.0008 0.0001 0.0002 0.0002 0.0001 0.0002 0.0001 0 0.0005
Bud Site 0.0023 0.0209 0.0113 0.0002 0.0018 0.0021 0.0016 0.0011 0.0055 0.0014 0.0003 0.0002 0.0007 0.0005 0.0005 0.0003 0.0002 0.0004
Cell Periphery 0.0002 0.0007 0.0005 0 0.0001 0.0002 0.0005 0.0002 0.0003 0.0002 0 0.0001 0.0003 0.0001 0.0001 0 0 0
Cytoplasm 0.2227 0.4398 0.2567 0.2334 0.1551 0.3593 0.3204 0.3082 0.2678 0.2986 0.3105 0.3498 0.2661 0.3699 0.2868 0.2009 0.285 0.3012
Cytoplasmic Foci 0.119 0.0989 0.1163 0.1159 0.1595 0.1226 0.101 0.1102 0.0835 0.0959 0.0813 0.0999 0.1026 0.1125 0.0934 0.1179 0.0858 0.1252
Eisosomes 0.0004 0.0001 0.0001 0 0.0001 0 0.0003 0 0.0005 0 0 0 0.0002 0 0 0 0 0
Endoplasmic Reticulum 0.0092 0.0043 0.0053 0.0032 0.0017 0.0025 0.0096 0.0059 0.0051 0.0026 0.0035 0.0051 0.0087 0.0045 0.0046 0.0024 0.0017 0.003
Endosome 0.2993 0.186 0.3146 0.5353 0.3135 0.3298 0.3042 0.2734 0.3772 0.3218 0.4754 0.3545 0.3911 0.3393 0.4318 0.5163 0.4985 0.4424
Golgi 0.0155 0.0062 0.022 0.0048 0.0218 0.0079 0.0236 0.0054 0.0226 0.0098 0.0055 0.0182 0.0124 0.0113 0.0113 0.0072 0.0057 0.0105
Lipid Particles 0.0094 0.0031 0.0058 0.0008 0.033 0.0082 0.0189 0.0054 0.0063 0.0023 0.0004 0.0011 0.0063 0.001 0.0025 0.0014 0.0004 0.0012
Mitochondria 0.0089 0.0019 0.0145 0.0019 0.0439 0.0072 0.0062 0.0013 0.0117 0.0034 0.0021 0.0075 0.0063 0.0068 0.0041 0.0017 0.0011 0.0074
None 0.2223 0.183 0.1283 0.0206 0.1751 0.0984 0.1163 0.2226 0.117 0.1404 0.0489 0.1058 0.1243 0.1074 0.0873 0.0329 0.0467 0.0604
Nuclear Periphery 0.0082 0.0023 0.0088 0.0015 0.0035 0.0022 0.0292 0.0021 0.003 0.0022 0.0018 0.0015 0.0052 0.0021 0.0024 0.0017 0.001 0.0014
Nucleolus 0.0007 0.0006 0.0009 0.0001 0.0006 0.0033 0.0004 0.0003 0.0005 0.0008 0.0001 0.0001 0.0005 0.0002 0.0002 0.0003 0 0.0002
Nucleus 0.004 0.0037 0.0058 0.0011 0.0022 0.0047 0.0063 0.0012 0.0016 0.0024 0.001 0.0013 0.0018 0.0026 0.0017 0.0016 0.0009 0.0012
Peroxisomes 0.007 0.0052 0.0125 0.0005 0.044 0.0026 0.0037 0.0007 0.0193 0.0008 0.0003 0.0027 0.0014 0.0011 0.0007 0.0007 0.0003 0.0016
Punctate Nuclear 0.0078 0.0017 0.0051 0.0005 0.0096 0.0029 0.0018 0.0009 0.0008 0.0006 0.0002 0.0006 0.0026 0.0009 0.0007 0.0022 0.0006 0.0011
Vacuole 0.0319 0.0279 0.0369 0.0598 0.0133 0.0329 0.0371 0.0525 0.0551 0.0923 0.0531 0.04 0.0551 0.0304 0.0548 0.0849 0.048 0.027
Vacuole Periphery 0.0061 0.0052 0.0114 0.0199 0.0059 0.0092 0.0096 0.0075 0.0142 0.021 0.0149 0.0099 0.0121 0.0087 0.0162 0.0266 0.0235 0.0097

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 7.8367 7.4725 6.9312 12.2506 15.5796 6.2659 13.4582 14.3422 13.8084 13.3324
Translational Efficiency 0.992 1.146 1.4525 0.8892 0.5823 1.8727 0.7945 0.9846 1.1448 0.7822

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2093 1404 392 1316 1450 1383 2755 1594 3543 2787 3147 2910

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 731.21 796.65 1170.27 1006.53 677.05 808.77 1006.04 1052.60 709.04 802.66 1026.50 1031.77
Standard Deviation 91.56 114.85 156.57 158.52 98.08 108.21 121.71 160.90 97.97 111.77 137.70 161.47
Intensity Change Log 2 — 0.123660 0.678484 0.461032 — 0.256467 0.571353 0.636623 — 0.189037 0.627970 0.548121

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000394 0.000515 0.000326 0.000239 0.000186 0.000232 0.000067 0.000773 0.000309 0.000374 0.000099 0.000531
Bud Neck 0.012215 0.008673 0.001944 0.008277 0.014366 0.007506 0.010222 0.007126 0.013095 0.008094 0.009191 0.007647
Bud Site 0.019365 0.018582 0.018512 0.031684 0.009758 0.011304 0.009969 0.038248 0.015433 0.014970 0.011033 0.035279
Cell Periphery 0.000117 0.000099 0.000076 0.000061 0.000087 0.000091 0.000021 0.000050 0.000105 0.000095 0.000028 0.000055
Cytoplasm 0.193663* 0.134501* 0.070688 0.167132* 0.158906* 0.106896* 0.188834* 0.194059* 0.179438* 0.120803* 0.174117* 0.181882*
Cytoplasmic Foci 0.400695* 0.412099* 0.180923* 0.084436 0.401075* 0.405780* 0.067611 0.136657 0.400850* 0.408963* 0.081726 0.113041
Eisosomes 0.000136 0.000075 0.000009 0.000011 0.000107 0.000096 0.000008 0.000014 0.000124 0.000086 0.000008 0.000012
Endoplasmic Reticulum 0.002652 0.001830 0.001943 0.001967 0.002621 0.002502 0.001298 0.000539 0.002639 0.002163 0.001378 0.001185
Endosome 0.140699 0.180512 0.137444 0.102433 0.191004 0.207392* 0.076351 0.138008 0.161287 0.193851 0.083961 0.121920
Golgi 0.046491 0.061118 0.074713 0.007251 0.037944 0.060684 0.003338 0.012623 0.042993 0.060902 0.012229 0.010194
Lipid Particles 0.013372 0.008361 0.002199 0.002790 0.021530 0.010538 0.001560 0.001670 0.016710 0.009441 0.001639 0.002177
Mitochondria 0.012718 0.014366 0.000779 0.002091 0.011193 0.020298 0.002925 0.002669 0.012094 0.017310 0.002658 0.002408
Mitotic Spindle 0.001675 0.007959 0.036989 0.015858 0.002808 0.007245 0.015365 0.011660 0.002139 0.007604 0.018058 0.013558
None 0.000604 0.000329 0.000094 0.000217 0.002948 0.000445 0.000662 0.000123 0.001563 0.000387 0.000591 0.000166
Nuclear Periphery 0.000189 0.000441 0.001358 0.001821 0.000713 0.000250 0.001780 0.000502 0.000403 0.000346 0.001727 0.001099
Nuclear Periphery Foci 0.000365 0.000451 0.008963 0.002252 0.001115 0.000289 0.000963 0.000634 0.000672 0.000371 0.001960 0.001366
Nucleolus 0.000581 0.000417 0.000395 0.001712 0.003042 0.000644 0.002706 0.000510 0.001588 0.000530 0.002418 0.001054
Nucleus 0.006221 0.003160 0.001332 0.008983 0.016229 0.004101 0.021260 0.003923 0.010317 0.003627 0.018777 0.006211
Peroxisomes 0.006530 0.009207 0.001470 0.003527 0.009302 0.007183 0.003063 0.006861 0.007664 0.008203 0.002865 0.005353
Vacuole 0.122000 0.112583 0.351564* 0.520749* 0.102975 0.113350 0.562502* 0.418505* 0.114214 0.112964 0.536227* 0.464743*
Vacuole Periphery 0.019320 0.024722 0.108278* 0.036506 0.012091 0.033177 0.029495 0.024847 0.016361 0.028918 0.039309 0.030120

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.74 0.10 1.05 2.46 1.20 -1.48 6.02 -3.41 -3.09 -4.15 -0.71 2.45 -1.64 -1.24 -4.44
Bud Neck 3.86 14.87 3.61 -0.09 -8.99 5.69 2.48 6.36 0.18 5.81 6.88 3.67 7.42 0.16 3.62
Bud Site 0.42 0.12 -3.93 -4.59 -3.58 -1.86 -0.13 -11.73 -11.03 -11.63 0.40 3.86 -9.69 -10.81 -13.15
Cell Periphery 0.86 1.97 2.39 1.75 0.99 -0.06 7.27 4.07 5.04 -5.41 0.88 6.12 3.76 3.75 -4.19
Cytoplasm 8.64 13.12 0.68 -6.49 -11.12 7.81 -6.74 -7.03 -14.50 -1.33 12.29 -1.96 -4.28 -14.78 -2.19
Cytoplasmic Foci -1.50 22.23 55.59 50.47 10.28 -0.62 56.36 39.76 40.37 -14.12 -1.49 76.32 65.54 62.92 -7.86
Eisosomes 5.80 13.79 13.64 12.40 -1.60 1.47 19.53 18.15 13.23 -4.57 5.52 20.10 19.28 18.04 -5.83
Endoplasmic Reticulum 2.22 1.72 1.82 0.10 0.35 0.19 2.99 4.83 5.44 5.18 1.44 4.70 5.15 3.92 1.24
Endosome -7.29 0.92 10.18 15.75 6.22 -2.50 22.76 10.96 14.18 -12.32 -7.71 24.19 13.60 20.57 -9.26
Golgi -4.63 -4.27 22.10 19.66 11.24 -7.22 18.25 12.67 18.34 -8.08 -8.07 20.87 24.52 26.70 2.65
Lipid Particles 4.70 14.34 12.04 6.04 -1.26 5.91 12.16 12.08 9.59 -0.54 7.31 18.64 17.39 11.27 -2.29
Mitochondria -1.16 14.87 12.82 10.48 -3.14 -4.81 8.41 8.04 10.56 0.94 -4.45 15.02 14.49 14.58 1.38
Mitotic Spindle -4.04 -6.42 -6.80 -3.30 3.50 -2.84 -8.41 -5.10 -2.34 2.34 -5.05 -11.36 -8.67 -3.96 2.82
None 1.40 2.83 2.09 1.14 -3.00 3.41 3.10 3.95 1.49 1.76 3.60 2.63 4.45 1.87 1.57
Nuclear Periphery -1.61 -4.14 -2.83 -2.28 -0.46 2.53 -5.23 0.84 -1.38 6.09 0.52 -9.01 -2.38 -2.57 2.81
Nuclear Periphery Foci -0.66 -4.22 -3.97 -3.85 3.13 5.21 -0.39 2.19 -2.60 2.29 2.96 -4.65 -2.99 -4.45 1.90
Nucleolus 1.78 1.62 -4.01 -4.63 -4.57 4.11 0.25 4.71 0.39 13.99 4.15 -3.86 2.17 -2.88 8.39
Nucleus 5.85 8.96 -3.27 -6.13 -7.49 6.37 -4.19 6.20 -0.62 16.34 7.68 -9.82 3.29 -4.63 13.55
Peroxisomes -3.05 7.93 6.28 6.79 -2.85 2.54 9.22 3.48 0.94 -5.85 -0.90 11.38 5.48 5.35 -5.49
Vacuole 1.76 -17.68 -46.33 -46.16 -11.06 -1.90 -68.87* -40.45 -37.91 13.92 0.27 -72.56* -60.01 -58.53 7.69
Vacuole Periphery -3.38 -12.40 -5.81 -2.81 10.40 -12.34 -12.15 -7.03 5.76 2.81 -10.62 -14.02 -7.97 1.96 5.96
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of RAVE complex (Rav1p, Rav2p, Skp1p); the RAVE complex associates with the V1 domain of the vacuolar membrane (H+)-ATPase (V-ATPase) and promotes assembly and reassembly of the holoenzyme
Localization
Cell Percentages cytoplasm (30%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-3

Rav2

Rav2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rav2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available