ORF
Human Ortholog
Description Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; YDR222W has a paralog, YLR225C, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.96 0.97 0.97 0.99 0.93 0.83 0.79 0.78 0.74 0.7 0.54 0.6 0.99 1.0 1.0 0.96 0.94 0.94 0.82 0.87 0.67 0.87 0.89 0.83
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.06 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.09 0 0 0.09 0.09 0.34 0.38 0.36 0.41 0.52 0.64 0.57 0 0 0 0 0 0.05 0.07 0 0.14 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 5 9 2 2 2
Bud 1 1 0 0 3 1 6 6 6 11 4 11 0 0 0 0 0 0 0 2 7 4 3 7
Bud Neck 0 1 2 0 4 2 2 0 1 6 0 3 1 6 4 0 2 2 2 0 2 2 0 3
Bud Site 0 0 0 0 0 0 0 2 2 1 2 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 3 0 0 1 3 1 0 1 2 1 0 5 1 7 4 9 4 1 4 0 2 1
Cytoplasm 408 223 293 159 237 241 311 260 304 304 128 196 321 522 506 184 269 208 333 208 211 207 302 264
Endoplasmic Reticulum 2 3 2 0 1 2 0 0 0 1 1 1 1 2 1 6 14 14 2 1 5 0 0 2
Endosome 0 0 0 1 0 0 1 0 0 1 0 0 1 0 1 3 3 2 4 2 5 1 1 2
Golgi 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 3 1 0 2 0 3 1 0 0
Mitochondria 37 6 6 14 24 100 149 119 169 228 153 188 0 0 0 0 9 12 27 10 43 5 8 12
Nucleus 0 0 1 1 2 0 0 1 2 0 2 3 2 0 1 1 1 0 0 0 1 0 1 0
Nuclear Periphery 1 0 0 0 0 1 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 0 1
Nucleolus 0 0 1 0 0 0 1 3 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0
Peroxisomes 0 0 0 1 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 2 0 0 0 2 2 12 12 17 6 2 7 0 0 0 0 5 1 2 1 5 3 4 7
Vac/Vac Membrane 0 2 0 0 2 2 2 1 2 5 2 6 0 0 0 2 5 5 3 2 3 1 3 4
Unique Cell Count 427 230 302 160 256 291 396 334 413 437 238 327 323 524 508 191 285 222 406 238 315 238 339 320
Labelled Cell Count 451 237 310 176 275 352 488 405 504 564 297 418 327 535 514 206 315 253 406 238 315 238 339 320


Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.2 3.9 3.8 3.6 3.3 2.8 2.9 2.8 2.8 2.6 2.4 2.5 5.5 5.1 5.0 5.7 4.9 5.0 5.7 5.5 5.9
Std Deviation (1e-4) 0.6 0.7 1.5 1.9 1.3 1.7 2.1 1.5 1.4 1.2 0.9 1.0 1.2 0.9 1.0 2.2 1.6 1.5 1.7 1.2 1.5
Intensity Change (Log2) – – – -0.07 -0.19 -0.4 -0.36 -0.4 -0.42 -0.53 -0.66 -0.59 0.54 0.44 0.41 0.61 0.39 0.41 0.59 0.56 0.65


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.098 1.6956 1.8165 1.6943 0.6772 1.4583 1.5988 0.5174 0.6598 0.6253 0.5499 0.273 -0.3283 -0.4118 -0.0901 0.1474 -0.102 -0.3135
Actin 0.0184 0.0018 0.0103 0.0048 0.0013 0.0061 0.052 0.0078 0.0255 0.007 0.0186 0.0018 0.0566 0.0013 0.0029 0.0038 0.054 0.0021
Bud 0.0009 0.0006 0.0008 0.0013 0.0009 0.0007 0.0063 0.0037 0.0003 0.0008 0.0027 0.0002 0.0037 0.0007 0.0092 0.0031 0.0004 0.0002
Bud Neck 0.0012 0.0003 0.0015 0.0004 0.0006 0.0057 0.0025 0.0003 0.001 0.0275 0.0007 0.0004 0.0029 0.0001 0.0003 0.0006 0.0008 0.0005
Bud Periphery 0.0026 0.0014 0.001 0.0031 0.0014 0.0017 0.0143 0.0019 0.0003 0.0027 0.01 0.0005 0.0042 0.0016 0.004 0.0039 0.0007 0.0006
Bud Site 0.0031 0.002 0.0062 0.0007 0.0012 0.0004 0.01 0.011 0.0066 0.0079 0.0067 0.0001 0.0072 0.0009 0.0108 0.0055 0.0014 0.0002
Cell Periphery 0.0002 0.0002 0.0002 0.0002 0.0001 0.0001 0.0046 0.0004 0.0001 0.0003 0.0003 0 0.0005 0.0002 0.0004 0.0003 0.0002 0
Cytoplasm 0.081 0.1952 0.2071 0.2356 0.1898 0.1296 0.0942 0.1973 0.281 0.2629 0.1554 0.2418 0.104 0.1766 0.2557 0.0965 0.1849 0.237
Cytoplasmic Foci 0.0274 0.0055 0.0095 0.0067 0.0045 0.0131 0.0206 0.0062 0.0119 0.0129 0.0093 0.0174 0.0226 0.0034 0.0076 0.0105 0.0092 0.0054
Eisosomes 0.0004 0.0001 0.0002 0.0002 0.0001 0.0001 0.001 0.0001 0.0002 0.0002 0.0005 0.0001 0.0005 0.0001 0.0002 0.0002 0.0004 0.0001
Endoplasmic Reticulum 0.0033 0.0012 0.0023 0.0031 0.0011 0.0015 0.0167 0.0019 0.003 0.0022 0.0034 0.0023 0.003 0.0013 0.0025 0.0011 0.0038 0.0035
Endosome 0.0083 0.0021 0.0047 0.0029 0.0006 0.0032 0.0501 0.0012 0.006 0.0148 0.0201 0.006 0.0194 0.0006 0.0043 0.0009 0.0198 0.0113
Golgi 0.0028 0.0001 0.0016 0.0002 0.0001 0.0009 0.0189 0.0002 0.007 0.0072 0.0028 0.0011 0.008 0.0001 0.0019 0.0002 0.0033 0.0049
Lipid Particles 0.007 0.0001 0.0017 0.0003 0.0002 0.0004 0.0257 0.0004 0.0077 0.0175 0.0187 0.0009 0.0147 0.0002 0.004 0.0007 0.0039 0.0041
Mitochondria 0.0105 0.0003 0.0044 0.0007 0.0005 0.001 0.0189 0.0004 0.0022 0.0095 0.0115 0.001 0.0082 0.0003 0.008 0.0013 0.0011 0.0031
None 0.7913 0.7682 0.7227 0.7083 0.7822 0.8197 0.5476 0.7575 0.6278 0.5785 0.7083 0.716 0.7076 0.8101 0.6733 0.8528 0.7008 0.7087
Nuclear Periphery 0.0082 0.0047 0.002 0.0024 0.0016 0.0006 0.0331 0.0012 0.0012 0.0039 0.0091 0.0034 0.0112 0.0005 0.0021 0.0005 0.0066 0.006
Nucleolus 0.001 0.0005 0.0007 0.0003 0.001 0.0003 0.0015 0.0004 0.0002 0.0093 0.0007 0.0002 0.0007 0.0001 0.0006 0.0019 0.0002 0.0002
Nucleus 0.0048 0.008 0.0115 0.0245 0.0074 0.0015 0.0389 0.0027 0.0075 0.0085 0.008 0.0013 0.0017 0.0007 0.0059 0.0039 0.0016 0.0013
Peroxisomes 0.0199 0.002 0.0025 0.0007 0.0003 0.0062 0.0184 0.0002 0.0074 0.0127 0.0053 0.0005 0.0063 0.0001 0.0013 0.0047 0.0015 0.008
Punctate Nuclear 0.0052 0.0019 0.0077 0.002 0.0043 0.0069 0.0072 0.0033 0.0018 0.0086 0.0052 0.0035 0.0127 0.0005 0.0031 0.005 0.0036 0.0013
Vacuole 0.0015 0.0024 0.0013 0.0017 0.0006 0.0003 0.0141 0.0017 0.001 0.003 0.0018 0.0009 0.0023 0.0006 0.0014 0.0024 0.0013 0.0006
Vacuole Periphery 0.001 0.0012 0.0003 0.0001 0.0002 0.0001 0.0036 0.0002 0.0001 0.0021 0.0008 0.0004 0.0019 0.0001 0.0005 0.0002 0.0006 0.0009

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 35.3655 21.3399 6.4513 7.0297 23.4996 22.9749 22.5756 12.1357 7.1794 22.9855
Translational Efficiency 1.5361 1.7664 0.7446 0.8338 1.5489 2.1914 1.2133 0.6834 1.2458 1.1425

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
256 161 335 1216 1547 1817 917 1096 1803 1978 1252 2312

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 646.75 751.30 891.46 1265.38 638.28 698.75 931.75 1190.11 639.48 703.03 920.97 1229.70
Standard Deviation 68.58 95.08 103.18 304.54 79.70 78.66 161.32 292.74 78.28 81.40 149.09 301.35
Intensity Change Log 2 — 0.216181 0.462962 0.968291 — 0.130587 0.545753 0.898834 — 0.174301 0.504679 0.934209

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000114 0.001371 0.000657 0.023091 0.000096 0.000602 0.001566 0.014126 0.000098 0.000664 0.001323 0.018841
Bud Neck 0.011905 0.035912 0.005336 0.040997 0.008716 0.036151 0.006488 0.027677 0.009169 0.036132 0.006180 0.034683
Bud Site 0.001822 0.016166 0.007821 0.096854 0.003130 0.016467 0.010518 0.060225 0.002944 0.016442 0.009796 0.079490
Cell Periphery 0.000140 0.000283 0.000219 0.000666 0.000125 0.000196 0.000368 0.000332 0.000127 0.000203 0.000328 0.000508
Cytoplasm 0.389939* 0.270833* 0.134217* 0.108718* 0.568391* 0.400295* 0.350253* 0.149021* 0.543054* 0.389757* 0.292448* 0.127824*
Cytoplasmic Foci 0.311410* 0.347251* 0.007995 0.072246 0.167289 0.260237* 0.033941 0.076236 0.187752* 0.267319* 0.026999 0.074137
Eisosomes 0.000193 0.000317 0.000094 0.000086 0.000103 0.000217 0.000104 0.000058 0.000115 0.000225 0.000101 0.000073
Endoplasmic Reticulum 0.000383 0.002851 0.009241 0.006030 0.000428 0.000886 0.006632 0.004189 0.000421 0.001046 0.007330 0.005157
Endosome 0.008353 0.029746 0.003309 0.043921 0.004316 0.019206 0.011133 0.044910 0.004889 0.020064 0.009039 0.044390
Golgi 0.000783 0.005439 0.000105 0.017109 0.001098 0.006487 0.000361 0.011427 0.001053 0.006402 0.000292 0.014415
Lipid Particles 0.010311 0.013429 0.003601 0.038870 0.004582 0.006964 0.007059 0.049501 0.005396 0.007490 0.006134 0.043909
Mitochondria 0.008213 0.005631 0.000890 0.006548 0.002414 0.013094 0.000617 0.006637 0.003237 0.012487 0.000690 0.006590
Mitotic Spindle 0.000592 0.004727 0.001250 0.300768* 0.001357 0.011596 0.017279 0.314599* 0.001249 0.011037 0.012990 0.307324*
None 0.002296 0.001136 0.005680 0.002669 0.007816 0.002251 0.015280 0.008424 0.007032 0.002160 0.012711 0.005397
Nuclear Periphery 0.000542 0.000907 0.002682 0.003374 0.000731 0.000377 0.002141 0.002572 0.000704 0.000420 0.002285 0.002994
Nuclear Periphery Foci 0.000794 0.001048 0.006073 0.035692 0.000300 0.000354 0.010799 0.030265 0.000370 0.000411 0.009534 0.033119
Nucleolus 0.001931 0.002468 0.001985 0.001266 0.001049 0.001401 0.002068 0.001830 0.001174 0.001488 0.002046 0.001533
Nucleus 0.190881* 0.131677* 0.725994* 0.059750 0.203075* 0.129863 0.394845* 0.071085 0.201344* 0.130011* 0.483451* 0.065123
Peroxisomes 0.009420 0.038503 0.000473 0.018420 0.002765 0.022155 0.004245 0.026222 0.003710 0.023486 0.003236 0.022119
Vacuole 0.049463 0.088797 0.082175 0.116415 0.021656 0.069541 0.124024 0.093151 0.025604 0.071109 0.112827 0.105387
Vacuole Periphery 0.000517 0.001508 0.000208 0.006510 0.000564 0.001659 0.000277 0.007514 0.000558 0.001647 0.000259 0.006986

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.79 -4.71 -6.67 -5.16 -5.89 -6.77 -5.73 -5.39 -4.92 -3.65 -6.36 -6.71 -8.56 -7.90 -6.61
Bud Neck -3.52 0.54 -16.06 -5.31 -17.03 -12.54 -0.70 -15.13 -4.96 -14.36 -12.96 -0.58 -23.77 -9.38 -22.79
Bud Site -4.50 -2.71 -22.12 -13.91 -17.91 -9.60 -7.69 -18.13 -12.75 -13.95 -10.41 -7.75 -28.11 -20.23 -22.71
Cell Periphery -1.92 -5.79 -12.99 -6.62 -10.61 -4.62 -13.50 -11.18 -8.42 -3.34 -4.96 -14.75 -16.90 -13.63 -9.84
Cytoplasm 5.02 15.38 16.45 7.11 -0.37 18.06 28.55 43.93 25.24 9.73 17.36 34.41 53.50 31.98 10.57
Cytoplasmic Foci -1.65 21.39 19.01 16.52 -11.08 -12.71 25.19 24.47 37.59 -1.19 -11.22 32.04 30.03 41.74 -4.61
Eisosomes -1.76 4.12 6.32 3.38 3.30 -5.72 -1.60 1.48 11.88 8.20 -5.90 -0.86 2.02 11.67 8.04
Endoplasmic Reticulum -1.57 -14.76 -15.02 -2.12 7.35 -1.32 -18.67 -12.82 -8.51 7.38 -1.81 -23.57 -20.03 -10.90 9.70
Endosome -4.41 2.98 -5.70 2.48 -9.69 -13.84 -6.48 -8.41 1.89 -2.30 -14.24 -5.67 -12.37 2.38 -5.51
Golgi -3.24 3.88 -3.59 0.57 -4.31 -8.23 4.79 -2.51 3.52 -3.53 -8.74 5.73 -4.16 3.13 -5.44
Lipid Particles -0.80 2.98 -4.96 -2.72 -11.58 -4.29 -4.00 -6.99 -5.89 -5.32 -3.26 -1.99 -11.64 -10.13 -10.44
Mitochondria 0.61 1.81 1.26 1.29 -4.44 -8.05 4.76 -0.53 7.02 -2.98 -6.84 3.81 0.39 7.59 -5.15
Mitotic Spindle -1.79 -2.24 -21.62 -19.88 -21.04 -5.27 -6.92 -19.96 -18.52 -15.95 -5.52 -7.04 -29.30 -26.84 -24.08
None 1.85 -2.23 -2.65 -7.47 0.59 5.06 -0.65 0.80 -6.09 1.35 5.11 -0.52 1.76 -7.25 2.14
Nuclear Periphery -0.71 -15.46 -13.77 -7.47 -3.96 0.82 -5.84 -8.07 -16.38 -3.94 0.76 -7.30 -10.41 -20.90 -5.79
Nuclear Periphery Foci -0.56 -2.09 -11.51 -11.63 -4.60 -0.46 -9.01 -9.87 -9.83 -0.28 -0.35 -8.83 -15.58 -15.55 -3.16
Nucleolus -0.62 -0.37 -2.76 -2.31 -2.60 -1.86 -3.79 -6.36 -5.92 -4.01 -1.55 -3.62 -8.18 -7.70 -4.81
Nucleus 3.32 -25.18 3.76 -0.85 32.20 11.28 -15.18 4.96 -4.30 17.75 11.80 -24.47 7.68 -3.93 29.66
Peroxisomes -3.82 5.87 1.43 4.21 -6.74 -13.38 -1.94 -4.41 6.57 -2.45 -13.37 0.03 -4.78 9.36 -3.81
Vacuole -3.66 -7.43 -21.68 -11.80 -7.72 -17.71 -23.12 -27.05 -20.10 -2.65 -16.95 -24.52 -39.04 -28.20 -5.65
Vacuole Periphery -3.13 3.24 -3.07 -0.69 -3.90 -8.27 4.87 -2.11 -0.46 -2.58 -8.83 5.72 -3.45 -0.61 -4.30
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; YDR222W has a paralog, YLR225C, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (26%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

YDR222W

YDR222W


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ydr222w-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available