Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the large subunit; also involved in homologous recombination in mitochondria; required for recombination-dependent mtDNA partitioning; involved in stimulation of mitochondrial DNA replication in response to oxidative stress
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.08 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.05 0 0 0 0 – 0 0 0 0 0 0 0 0.11 0.09 0.08 0 0 0 0 0 0
Cytoplasm 0 0 0 0.05 0 0 0 – 0 0 0 0 0 0 0 0.3 0.25 0.17 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.06 0.09 0.08 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0.05 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0.07 0.24 0.2 0.34 0 0.07 – 0 0 0 0 0.1 0.1 0.19 0.27 0.47 0.12 0 0.15 0.05 0.07 0.08 0.09
Mitochondria 0.92 0.94 0.86 0.89 0.73 0.88 0.71 – 0.85 0.83 0.9 0.87 0.9 0.9 0.87 0.14 0.16 0.17 0.85 0.74 0.86 0.75 0.76 0.71
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0.06 0 0 0.07 0.08 – 0.1 0.09 0.08 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.1 0.06 0.07 0 0.05 0.12 0.12 – 0.1 0.08 0.07 0.08 0.05 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.08 0 0.12 0 0 0 0.08 0.08 0.1
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.08 0 0 0 0 0 0
Vac/Vac Membrane 0 0.06 0.07 0.05 0.13 0.08 0.12 – 0.08 0.07 0.05 0.05 0 0.06 0 0.16 0.19 0.25 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 2 6 1 1 3 – 2 2 3 0 0 2 0 4 1 0 0 1 0 2 7 9
Bud 0 0 0 6 6 5 6 – 12 6 11 11 2 2 1 3 0 2 0 0 0 0 1 2
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
Bud Site 0 0 0 0 0 0 1 – 0 2 4 4 0 0 1 1 0 0 – – – – – –
Cell Periphery 0 2 7 9 4 1 7 – 6 9 5 3 0 6 3 14 3 2 0 0 0 0 0 0
Cytoplasm 1 0 2 12 10 9 16 – 12 11 11 6 2 4 4 38 8 4 0 0 0 0 0 0
Endoplasmic Reticulum 0 1 0 2 2 0 4 – 0 5 2 7 1 0 0 8 3 2 0 0 0 0 0 0
Endosome 1 0 3 3 8 3 25 – 10 12 8 12 2 3 5 4 0 0 3 1 2 1 0 2
Golgi 0 6 33 48 91 1 41 – 12 17 24 25 17 23 49 34 15 3 4 14 7 7 15 20
Mitochondria 99 85 118 214 197 311 391 – 471 501 484 606 154 216 229 18 5 4 130 69 134 81 139 155
Nucleus 0 0 0 1 0 3 5 – 4 0 1 2 1 1 0 1 1 1 0 0 0 0 0 0
Nuclear Periphery 2 3 8 6 6 23 46 – 53 53 45 62 6 9 7 0 0 0 1 0 0 2 0 1
Nucleolus 11 5 10 3 13 42 65 – 58 50 35 59 8 5 10 3 0 1 2 0 0 1 1 2
Peroxisomes 1 0 3 5 8 4 7 – 2 12 5 10 6 10 11 10 0 3 3 1 6 9 14 21
SpindlePole 0 0 0 0 2 1 7 – 1 5 4 7 0 0 0 3 1 2 0 0 2 0 1 1
Vac/Vac Membrane 4 5 9 12 34 27 67 – 42 44 25 38 7 14 11 20 6 6 1 3 0 1 1 1
Unique Cell Count 108 90 138 241 271 352 548 555 600 537 698 171 240 262 125 32 24 154 93 156 109 185 220
Labelled Cell Count 119 107 195 327 382 431 691 685 729 667 852 206 295 331 161 43 30 154 93 156 109 185 220


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 11.2 12.1 11.5 11.8 12.7 8.5 12.1 – 11.4 11.5 11.5 11.4 14.2 14.4 13.8 13.0 14.7 13.3 12.4 13.0 13.0
Std Deviation (1e-4) 2.5 2.5 2.3 2.2 2.5 2.3 2.9 – 2.7 3.0 3.1 3.0 3.1 2.5 2.5 3.8 3.4 3.2 3.4 3.2 3.0
Intensity Change (Log2) – – – 0.04 0.15 -0.44 0.07 – -0.01 0.0 0.0 -0.01 0.31 0.32 0.27 0.17 0.35 0.21 0.11 0.18 0.18

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery -0.6 0 0 0 – 0 0 0 0 0 0 0 1.8 0 0
Cytoplasm 1.8 0 0 0 – 0 0 0 0 0 0 0 6.5 0 0
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 1.3 – 0 0 0 0 0 0 0 0 0 0
Golgi -0.9 2.0 -9.3 -5.6 – -9.3 -8.9 -7.3 -8.6 -3.3 -3.8 -1.2 0.6 2.6 -1.2
Mitochondria 0.9 -2.9 0.9 -3.4 – -0.2 -0.6 1.6 0.4 1.2 1.3 0.5 -11.5 -8.0 -7.2
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery -1.6 0 0.3 1.0 – 1.4 1.2 1.0 1.2 -1.0 -0.9 -1.6 0 0 0
Nucleolus 0 -1.0 1.5 1.6 – 1.1 0.4 -0.3 0.5 -1.0 -2.5 -1.5 -1.8 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 2.2 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole -0.6 1.9 0.4 1.9 – 0.4 0.3 -0.9 -0.5 -1.0 -0.3 -1.0 2.5 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 11.1895 11.4979 10.6833 9.0789 8.2654 10.5031 11.6557 13.2346 12.3176 11.1346 9.9036 13.188 16.6321 15.1836 15.9121 15.8757 15.1517 15.1266
Actin 0.0059 0.006 0.0148 0.0022 0.0453 0.0026 0.0522 0.0138 0.0056 0.0028 0.0186 0.0019 0.0029 0.0051 0.0025 0.0045 0.0002 0.0017
Bud 0.0001 0.0001 0.0005 0.0001 0.0002 0 0.0012 0.0037 0.0005 0 0.0032 0.0001 0.0001 0.0002 0.0002 0.0001 0 0
Bud Neck 0.0001 0.0001 0.0002 0 0.0004 0.0001 0.0021 0.0001 0.0002 0.0001 0.0007 0.0001 0.0001 0.0001 0.0003 0 0 0
Bud Periphery 0.0002 0.0001 0.0009 0.0004 0.0005 0.0001 0.0024 0.002 0.0008 0.0001 0.0059 0.0002 0.0002 0.0003 0.0006 0.0001 0 0.0001
Bud Site 0.0003 0.0004 0.0012 0 0.0006 0 0.0037 0.0055 0.0029 0.0001 0.0222 0.0001 0.0006 0.0013 0.0007 0.0001 0 0
Cell Periphery 0.0001 0.0001 0.0001 0.0001 0.0001 0 0.0003 0.0001 0.0002 0.0001 0.0002 0.0001 0.0001 0.0002 0.0002 0 0 0
Cytoplasm 0.0015 0 0.0002 0 0.0012 0.0002 0.0022 0 0 0 0.0001 0.0006 0.0013 0 0.0001 0 0 0
Cytoplasmic Foci 0.0071 0.0004 0.0036 0 0.0035 0.0015 0.01 0.0016 0.0009 0.0061 0.0072 0.001 0.0047 0.0011 0.0015 0.001 0.0001 0.0002
Eisosomes 0.0002 0.0001 0.0003 0.0007 0.0005 0.0002 0.0009 0.0002 0.0002 0.0001 0.0003 0.0002 0.0003 0.0003 0.0001 0.0001 0 0.0002
Endoplasmic Reticulum 0.0007 0 0.0001 0 0.002 0.0003 0.0012 0 0 0 0.0001 0.0001 0.0008 0 0.0002 0 0 0.0001
Endosome 0.0083 0.0016 0.0025 0 0.0122 0.0026 0.0131 0.0035 0.0024 0.0037 0.0028 0.0069 0.0033 0.001 0.0066 0.0004 0.0002 0.0019
Golgi 0.0062 0.0106 0.0064 0.0002 0.0085 0.0065 0.0165 0.026 0.012 0.0167 0.0137 0.0115 0.008 0.0051 0.0072 0.0041 0.0007 0.0058
Lipid Particles 0.014 0.0016 0.0076 0.0002 0.0211 0.0028 0.0315 0.0019 0.0119 0.0423 0.03 0.0009 0.0176 0.0055 0.0106 0.0006 0.0062 0.0007
Mitochondria 0.9363 0.9718 0.943 0.9951 0.8687 0.9735 0.808 0.9298 0.9461 0.9199 0.8552 0.942 0.9398 0.969 0.9529 0.9849 0.9896 0.9857
None 0.0017 0 0.0004 0 0.0014 0.0002 0.0028 0 0 0 0.0003 0.0001 0.0016 0 0.0001 0 0 0
Nuclear Periphery 0.0005 0 0.0005 0 0.0112 0.0023 0.01 0 0.0001 0 0.0003 0.0065 0.0013 0.0001 0.0003 0 0 0.0001
Nucleolus 0.0006 0.0001 0.0017 0 0.0018 0.0002 0.0008 0.0001 0.0012 0.0001 0.0014 0.0003 0.0008 0.0001 0.0006 0 0.0001 0
Nucleus 0.0003 0 0.0006 0 0.0022 0.0003 0.0108 0 0.0006 0 0.0005 0.003 0.0007 0.0001 0.0002 0 0 0
Peroxisomes 0.0072 0.0043 0.0034 0.0004 0.0081 0.0007 0.018 0.0101 0.0033 0.0055 0.0326 0.0009 0.004 0.0073 0.0022 0.0038 0.0017 0.0016
Punctate Nuclear 0.0005 0 0.0015 0 0.0068 0.0046 0.0043 0 0 0.0004 0.0026 0.0205 0.0028 0 0.0002 0 0 0
Vacuole 0.0021 0.0006 0.0017 0.0001 0.0009 0.0002 0.0027 0.0004 0.0018 0.0003 0.0007 0.0007 0.0014 0.0005 0.0037 0.0001 0.0002 0.0002
Vacuole Periphery 0.006 0.002 0.009 0.0004 0.0026 0.0011 0.0056 0.0012 0.0091 0.0017 0.0011 0.0025 0.0075 0.0028 0.0088 0.0003 0.0009 0.0014

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 29.975 37.659 25.795 35.0089 37.8135 45.3425 48.6946 41.5144 52.1116 47.2056
Translational Efficiency 1.3471 1.2122 1.7937 1.3593 1.087 1.2395 1.1615 1.2836 1.2502 1.1719

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1360 1189 657 1541 1336 2386 770 863 2696 3575 1427 2404

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1016.71 1275.79 1797.19 1689.93 1132.95 1274.99 1641.36 1703.85 1074.31 1275.26 1713.11 1694.93
Standard Deviation 197.24 273.86 308.27 319.26 189.97 245.06 295.52 332.18 202.21 255.00 311.30 324.03
Intensity Change Log 2 — 0.327483 0.821835 0.733055 — 0.170402 0.534808 0.588714 — 0.246830 0.677692 0.658785

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.003293 0.008087 0.006819 0.005837 0.002423 0.004543 0.008550 0.013962 0.002862 0.005722 0.007753 0.008754
Bud Neck 0.001164 0.001291 0.004169 0.001317 0.000716 0.000664 0.003437 0.002205 0.000942 0.000873 0.003774 0.001636
Bud Site 0.002527 0.001717 0.002006 0.002305 0.001020 0.000681 0.003545 0.004649 0.001780 0.001025 0.002836 0.003146
Cell Periphery 0.000488 0.000190 0.000107 0.000233 0.000061 0.000101 0.000162 0.000616 0.000276 0.000131 0.000137 0.000370
Cytoplasm 0.000298 0.000350 0.000378 0.000351 0.000263 0.000198 0.000499 0.000687 0.000281 0.000249 0.000443 0.000472
Cytoplasmic Foci 0.003817 0.015556 0.034949 0.007809 0.013954 0.006041 0.025980 0.007161 0.008840 0.009205 0.030110 0.007576
Eisosomes 0.000301 0.000773 0.000444 0.000443 0.000160 0.000315 0.000454 0.001347 0.000231 0.000467 0.000449 0.000768
Endoplasmic Reticulum 0.000184 0.000224 0.000389 0.000221 0.000162 0.000101 0.000176 0.000630 0.000173 0.000142 0.000274 0.000368
Endosome 0.003862 0.004785 0.005076 0.002820 0.004469 0.003648 0.005502 0.003839 0.004163 0.004026 0.005306 0.003186
Golgi 0.008365 0.038260 0.065877 0.035783 0.018903 0.017491 0.028573 0.038589 0.013587 0.024399 0.045748 0.036791
Lipid Particles 0.002909 0.006524 0.008473 0.002205 0.005055 0.004096 0.004483 0.003860 0.003973 0.004904 0.006320 0.002799
Mitochondria 0.956491 0.891223 0.805993 0.907393 0.929820 0.948109 0.874441 0.885571 0.943274 0.929189 0.842927 0.899559
Mitotic Spindle 0.000241 0.001320 0.009144 0.002117 0.001658 0.000203 0.005714 0.002209 0.000943 0.000574 0.007293 0.002150
None 0.000798 0.001067 0.003323 0.001778 0.000747 0.000661 0.001410 0.001842 0.000773 0.000796 0.002291 0.001801
Nuclear Periphery 0.000181 0.000126 0.002573 0.000473 0.000119 0.000052 0.000547 0.000534 0.000150 0.000076 0.001480 0.000495
Nuclear Periphery Foci 0.000346 0.000137 0.001145 0.000266 0.000198 0.000105 0.000356 0.000234 0.000273 0.000116 0.000719 0.000255
Nucleolus 0.000361 0.000709 0.001189 0.000225 0.000335 0.000272 0.001026 0.000279 0.000348 0.000417 0.001101 0.000244
Nucleus 0.000132 0.000339 0.000144 0.000048 0.000497 0.000107 0.000122 0.000180 0.000313 0.000184 0.000132 0.000095
Peroxisomes 0.011685 0.019665 0.012383 0.006126 0.013609 0.008935 0.020695 0.006359 0.012638 0.012504 0.016868 0.006209
Vacuole 0.001233 0.003664 0.009811 0.006954 0.002886 0.002256 0.006390 0.010447 0.002052 0.002724 0.007965 0.008208
Vacuole Periphery 0.001325 0.003993 0.025607 0.015297 0.002947 0.001421 0.007939 0.014801 0.002128 0.002277 0.016073 0.015119

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.54 -2.51 -2.18 1.72 0.72 -1.95 -3.94 -4.74 -3.98 -2.06 -3.43 -4.62 -5.18 -2.74 -0.77
Bud Neck -0.35 -4.79 -0.49 -0.14 4.78 0.27 -6.03 -3.27 -3.33 1.91 0.34 -7.42 -2.79 -3.30 5.23
Bud Site 0.80 0.55 0.07 -0.86 -0.58 0.83 -2.68 -2.95 -3.35 -0.77 1.49 -1.59 -2.01 -3.58 -0.52
Cell Periphery 2.20 3.11 2.00 -0.67 -3.70 -1.83 -2.58 -2.89 -2.67 -2.32 2.20 2.13 -1.01 -3.17 -3.12
Cytoplasm -0.42 -0.66 -0.52 -0.24 0.13 1.02 -2.56 -2.03 -2.36 -0.99 0.46 -2.09 -1.94 -2.64 -0.54
Cytoplasmic Foci -8.09 -9.72 -4.62 5.14 8.41 5.41 -4.02 4.13 -1.12 6.62 -0.38 -9.78 1.34 1.96 10.60
Eisosomes -5.75 -2.67 -2.56 3.97 0.01 -5.83 -7.01 -1.94 -1.69 -1.46 -6.71 -6.38 -2.42 -1.35 -1.43
Endoplasmic Reticulum -0.65 -1.47 -0.54 0.06 1.23 1.76 -0.37 -2.41 -2.75 -2.35 0.89 -1.49 -2.43 -2.96 -0.95
Endosome -0.95 -1.31 1.31 2.69 3.33 1.02 -0.95 0.71 -0.33 1.61 0.22 -1.58 1.71 1.73 3.45
Golgi -8.71 -10.14 -8.82 0.57 4.81 0.60 -2.60 -4.75 -5.33 -2.05 -5.96 -9.70 -9.18 -4.62 2.31
Lipid Particles -2.80 -4.75 0.84 4.01 6.72 0.99 0.53 0.81 0.15 0.41 -1.22 -2.97 1.61 2.88 4.63
Mitochondria 8.50 12.88 7.57 -1.91 -8.38 -3.05 5.43 4.84 7.56 -0.90 3.14 12.99 8.18 5.73 -6.86
Mitotic Spindle -1.69 -4.49 -2.77 -0.90 3.35 2.97 -2.42 -0.74 -3.39 2.04 1.16 -4.97 -2.25 -3.03 3.81
None -2.75 -12.61 -7.91 -5.91 7.29 1.57 -6.38 -4.49 -4.88 -1.68 -0.44 -13.63 -8.89 -8.98 3.29
Nuclear Periphery 0.38 -4.65 -1.79 -4.31 4.19 4.44 -6.38 -1.85 -2.15 0.05 1.01 -5.48 -2.89 -4.39 3.93
Nuclear Periphery Foci 0.76 -2.20 0.27 -1.96 3.54 1.97 -2.61 -0.67 -2.13 1.56 1.11 -2.49 0.09 -2.80 3.76
Nucleolus -0.82 -2.03 0.66 1.26 2.67 0.34 -1.53 0.30 -0.09 1.72 -0.37 -2.44 0.77 1.17 3.00
Nucleus -0.92 -0.19 1.31 1.33 2.35 0.90 0.86 0.68 -0.62 -0.53 0.55 0.82 0.96 0.92 0.63
Peroxisomes -2.73 -0.26 2.77 5.30 2.61 2.33 -2.16 3.33 1.56 4.65 0.08 -1.95 4.39 4.84 5.39
Vacuole -2.96 -7.39 -6.20 -2.86 1.96 0.83 -3.31 -4.17 -4.59 -2.16 -1.30 -7.63 -6.87 -5.93 -0.31
Vacuole Periphery -2.68 -9.18 -9.35 -6.48 3.42 2.99 -3.89 -6.97 -8.17 -3.43 -0.34 -9.84 -11.38 -11.13 0.51
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the large subunit; also involved in homologous recombination in mitochondria; required for recombination-dependent mtDNA partitioning; involved in stimulation of mitochondrial DNA replication in response to oxidative stress
Localization
Cell Percentages mitochondrion (99%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Mhr1

Mhr1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mhr1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available