Standard name
Human Ortholog
Description ER membrane protein involved in a late step of GPI anchor assembly; involved in the addition of phosphoethanolamine to the multiply mannosylated glycosylphosphatidylinositol (GPI) intermediate; human PIG-Fp is a functional homolog
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.05 0 0 0.11 0.07 0.06 0 – 0.05 0.06 0.05 0.1 0 0 0 0.06 – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – – – –
Cell Periphery 0 0 0 0 0.07 0 0.05 – 0 0.06 0 0.08 0.09 0.14 0.14 0.25 – – 0 0 0 0 0 0
Cytoplasm 0 0.07 0.07 0.15 0.09 0.15 0.14 – 0.21 0.14 0.26 0.14 0 0.07 0.05 0.19 – – 0 0 0 0 0 0
Endoplasmic Reticulum 0.76 0.6 0.64 0.37 0.67 0.44 0.41 – 0.5 0.54 0.4 0.39 0.92 0.84 0.85 0.06 – – 0.84 0.8 0.87 0.9 0.83 0.86
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Golgi 0.11 0 0.13 0.09 0.15 0 0.05 – 0 0 0 0 0.06 0 0 0.31 – – 0 0 0 0 0 0
Mitochondria 0.11 0 0 0.13 0 0.28 0 – 0.19 0.16 0.19 0.27 0 0 0 0 – – 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.06 – – 0 0 0 0 0 0
Nuclear Periphery 0.29 0.06 0.1 0 0 0 0 – 0 0 0 0.06 0.12 0.1 0.05 0 – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Vac/Vac Membrane 0.18 0.35 0.3 0.3 0.23 0.27 0.42 – 0.21 0.18 0.15 0.21 0 0 0.05 0.12 – – 0 0.06 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 3 0 7 13 13 10 3 – 8 11 10 27 5 7 5 1 – – 1 2 3 1 6 4
Bud 0 0 1 1 2 3 1 – 1 2 4 6 0 0 0 0 – – 0 2 0 0 2 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – – – –
Cell Periphery 1 1 5 4 12 6 10 – 5 12 9 21 16 28 30 4 – – 0 0 0 0 4 3
Cytoplasm 1 13 15 17 16 26 29 – 35 27 57 37 6 13 11 3 – – 0 6 1 1 1 5
Endoplasmic Reticulum 42 114 142 43 124 74 87 – 84 104 87 102 162 166 177 1 – – 81 188 226 114 165 186
Endosome 0 0 1 1 0 0 2 – 2 0 0 3 0 0 1 0 – – 0 0 2 0 1 0
Golgi 6 3 29 11 27 1 10 – 2 1 2 2 11 7 6 5 – – 3 3 4 0 3 4
Mitochondria 6 3 1 15 2 47 4 – 32 30 41 72 3 1 0 0 – – 2 4 5 3 6 1
Nucleus 0 0 0 1 1 4 4 – 1 4 5 5 0 0 0 1 – – 0 0 0 0 0 1
Nuclear Periphery 16 11 22 4 1 3 8 – 3 3 5 16 21 19 10 0 – – 3 8 7 1 1 0
Nucleolus 1 0 0 1 0 0 0 – 0 1 0 0 0 0 0 0 – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Vac/Vac Membrane 10 66 67 35 42 46 89 – 35 34 33 56 4 7 10 2 – – 0 13 5 0 3 5
Unique Cell Count 55 190 222 117 184 169 212 169 191 218 263 177 198 209 16 97 236 261 128 198 217
Labelled Cell Count 86 211 290 146 240 220 247 208 229 253 347 228 248 250 17 97 236 261 128 198 217


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 15.2 15.4 15.0 13.9 14.2 9.1 12.7 – 10.9 10.7 10.5 10.4 14.8 15.7 14.8 19.9 – – 13.7 15.3 15.9
Std Deviation (1e-4) 3.3 3.0 2.7 3.2 2.4 2.4 2.7 – 2.3 2.3 2.5 2.1 2.4 2.8 2.2 4.3 – – 2.4 2.9 2.9
Intensity Change (Log2) – – – -0.11 -0.08 -0.72 -0.24 – -0.46 -0.48 -0.51 -0.53 -0.01 0.06 -0.02 0.41 – – -0.13 0.03 0.08


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 3.0 1.8 1.3 0 – 0.8 1.3 0.8 3.1 -0.2 0.2 -0.5 0 – –
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 – –
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 – –
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 – –
Cell Periphery 0 2.1 0 1.4 – 0 2.1 1.1 2.8 3.0 4.5 4.6 0 – –
Cytoplasm 2.3 0.7 2.8 2.4 – 4.1 2.5 5.5 2.6 -1.5 -0.1 -0.7 0 – –
Endoplasmic Reticulum -4.8 0.7 -4.0 -4.8 – -2.8 -2.0 -5.0 -5.5 6.4 4.6 4.9 -4.6 – –
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 – –
Golgi -1.0 0.5 -4.6 -3.0 – -4.3 -4.9 -5.0 -5.5 -2.3 -3.5 -3.9 0 – –
Mitochondria 5.1 0 8.2 0 – 6.5 5.9 6.6 8.3 0 0 0 0 – –
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 – –
Nuclear Periphery -2.1 -4.1 -3.3 -2.5 – -3.3 -3.5 -3.3 -1.6 0.6 -0.1 -2.0 0 – –
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 – –
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 – –
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 – –
Vacuole -0.1 -1.7 -0.6 2.6 – -2.1 -2.9 -3.8 -2.2 -7.2 -7.2 -6.9 0 – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 8.7458 9.8718 9.5005 9.4128 7.3841 9.8137 12.2165 13.5195 12.8676 13.3075 12.2201 12.4967 15.6688 16.1895 15.8998 15.2428 18.0904 16.4517
Actin 0.0375 0.0006 0.0072 0.0315 0.0035 0.008 0.0042 0.0002 0.0145 0.0004 0.0428 0.0102 0.0256 0.0004 0.0066 0.0001 0.0155 0.0026
Bud 0.0004 0.0001 0.0003 0.0003 0.0001 0.0001 0.0003 0 0.0002 0 0.0059 0.0001 0.0002 0 0.0002 0 0.0002 0
Bud Neck 0.0008 0.0003 0.0007 0.0003 0.0006 0.0003 0.0004 0.0001 0.0005 0.0001 0.0009 0.0006 0.0004 0 0.0033 0.0001 0.0043 0.0001
Bud Periphery 0.0007 0.0002 0.0003 0.0004 0.0002 0.0003 0.0005 0.0001 0.0002 0.0001 0.0112 0.0002 0.0003 0 0.0003 0.0001 0.0003 0.0001
Bud Site 0.0012 0.0002 0.0007 0.001 0.0007 0.0001 0.0019 0.0001 0.0052 0 0.0034 0.0001 0.0003 0 0.0146 0 0.0005 0
Cell Periphery 0.0007 0.0024 0.0003 0.0011 0.0003 0.0001 0.0007 0.0008 0.0006 0.0003 0.0009 0.0002 0.0003 0.0003 0.0009 0.0027 0.0003 0.0001
Cytoplasm 0.0108 0.0076 0.0093 0.0014 0.0064 0.0015 0.0106 0.0168 0.0143 0.0012 0.0027 0.0039 0.0054 0.0051 0.0229 0.0008 0.0481 0.0255
Cytoplasmic Foci 0.0117 0.0005 0.0083 0.0034 0.0106 0.0048 0.0099 0.0011 0.0132 0.001 0.0035 0.001 0.0105 0.0001 0.0034 0 0.0044 0.0006
Eisosomes 0.0003 0.0001 0.0001 0.0001 0.0002 0 0.0001 0 0.0001 0 0.0002 0 0.004 0 0.0001 0 0.0001 0
Endoplasmic Reticulum 0.6752 0.917 0.8709 0.8619 0.7367 0.8629 0.7219 0.9418 0.8841 0.91 0.839 0.8781 0.7508 0.9787 0.9031 0.9264 0.8842 0.9219
Endosome 0.0387 0.0045 0.0136 0.0197 0.048 0.018 0.0507 0.0094 0.0173 0.0188 0.0219 0.0169 0.0164 0.0022 0.0031 0.0023 0.006 0.0037
Golgi 0.0179 0.0028 0.0098 0.0109 0.023 0.0093 0.0125 0.0015 0.0137 0.0169 0.0106 0.0098 0.0076 0.0007 0.0011 0.0002 0.0035 0.0007
Lipid Particles 0.0159 0.0059 0.0116 0.0309 0.0243 0.017 0.0078 0.0085 0.0103 0.0053 0.0318 0.004 0.0214 0.0004 0.0014 0.0033 0.0031 0.0024
Mitochondria 0.0107 0.0027 0.0149 0.006 0.0103 0.0123 0.01 0.0016 0.0036 0.0151 0.0084 0.0033 0.0041 0.0005 0.0017 0.0035 0.0003 0.0006
None 0.0048 0 0.0006 0.0001 0.0182 0.0002 0.002 0.0001 0.0004 0 0.0003 0.0002 0.0189 0 0.0047 0.0001 0.0003 0.0005
Nuclear Periphery 0.1445 0.0428 0.037 0.0189 0.0787 0.0576 0.1079 0.0117 0.0134 0.0243 0.012 0.0614 0.0972 0.0088 0.0248 0.0461 0.0178 0.0331
Nucleolus 0.0006 0 0.0003 0 0.0025 0.0001 0.0006 0 0.0001 0 0.0001 0 0.0011 0 0.0002 0 0.0002 0.0003
Nucleus 0.007 0.0018 0.0016 0.0005 0.0053 0.0017 0.0397 0.0008 0.0008 0.0016 0.0004 0.0038 0.0046 0.0003 0.001 0.0011 0.0007 0.0028
Peroxisomes 0.0025 0 0.0041 0.0019 0.002 0.0013 0.0044 0 0.0027 0.0002 0.0003 0.0002 0.0107 0 0.0008 0 0.0018 0.0003
Punctate Nuclear 0.0055 0.0001 0.0006 0.0002 0.0177 0.0005 0.0018 0.0001 0.0008 0 0.0006 0.0005 0.0129 0 0.0021 0 0.0063 0.0025
Vacuole 0.0064 0.008 0.0039 0.0051 0.0039 0.0021 0.0066 0.0046 0.0033 0.0027 0.0021 0.0031 0.003 0.0018 0.0018 0.0078 0.001 0.0011
Vacuole Periphery 0.0063 0.0022 0.0038 0.0043 0.0067 0.0018 0.0057 0.0006 0.0007 0.0018 0.0011 0.0023 0.0044 0.0005 0.0018 0.0053 0.0008 0.0009

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 19.226 26.9012 6.6539 15.6207 32.5139 11.6963 20.7776 25.4972 15.4388 27.9091
Translational Efficiency 2.1147 1.479 2.9466 1.356 0.9805 2.923 1.9632 1.1005 1.7556 1.4396

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
70 790 268 1591 1640 1650 2394 205 1710 2440 2662 1796

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1119.82 1390.07 1822.00 1683.06 1091.48 1255.21 1607.27 2053.92 1092.64 1298.87 1628.89 1725.39
Standard Deviation 204.50 240.67 256.62 337.20 177.76 216.84 262.90 279.97 179.02 233.52 270.11 351.53
Intensity Change Log 2 — 0.311891 0.702256 0.587820 — 0.201643 0.558327 0.912094 — 0.258526 0.633007 0.756978

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001144 0.003850 0.000488 0.002068 0.000813 0.003725 0.001067 0.000483 0.000826 0.003766 0.001009 0.001887
Bud Neck 0.001708 0.000324 0.003690 0.003022 0.000208 0.001146 0.000571 0.007971 0.000270 0.000880 0.000885 0.003587
Bud Site 0.014233 0.005939 0.002479 0.012688 0.002978 0.008560 0.004097 0.010010 0.003439 0.007712 0.003934 0.012383
Cell Periphery 0.001502 0.001243 0.001604 0.002469 0.000743 0.001554 0.002570 0.003994 0.000774 0.001453 0.002472 0.002643
Cytoplasm 0.006290 0.003977 0.003050 0.024099 0.005388 0.028825 0.005870 0.001495 0.005425 0.020780 0.005586 0.021519
Cytoplasmic Foci 0.020809 0.006222 0.001608 0.011844 0.004247 0.031117 0.001717 0.001235 0.004925 0.023057 0.001706 0.010633
Eisosomes 0.000047 0.000063 0.000032 0.000075 0.000038 0.000148 0.000055 0.000056 0.000039 0.000120 0.000052 0.000073
Endoplasmic Reticulum 0.837456* 0.920125* 0.864430* 0.742957* 0.942912* 0.660160* 0.933086* 0.884391* 0.938595* 0.744329* 0.926174* 0.759101*
Endosome 0.021467 0.016936 0.015904 0.030236 0.009554 0.035354 0.011298 0.018103 0.010041 0.029391 0.011762 0.028851
Golgi 0.010299 0.008183 0.002184 0.013875 0.003618 0.026462 0.005982 0.004504 0.003891 0.020544 0.005600 0.012806
Lipid Particles 0.012120 0.003193 0.004811 0.032036 0.003421 0.031590 0.006882 0.017986 0.003777 0.022396 0.006674 0.030433
Mitochondria 0.015184 0.001142 0.001033 0.001663 0.001697 0.008161 0.000574 0.000278 0.002249 0.005889 0.000621 0.001505
Mitotic Spindle 0.001136 0.001741 0.000426 0.007972 0.000101 0.003984 0.000249 0.003154 0.000144 0.003258 0.000266 0.007422
None 0.000271 0.001661 0.000023 0.003063 0.002248 0.009539 0.001336 0.000329 0.002167 0.006988 0.001204 0.002751
Nuclear Periphery 0.000612 0.002428 0.036025 0.010276 0.004496 0.031502 0.001564 0.006157 0.004337 0.022089 0.005034 0.009806
Nuclear Periphery Foci 0.004606 0.013494 0.047337 0.067117 0.013740 0.082617 0.009895 0.018094 0.013366 0.060237 0.013664 0.061522
Nucleolus 0.001181 0.000068 0.000009 0.000450 0.000030 0.000794 0.000012 0.000024 0.000078 0.000559 0.000012 0.000402
Nucleus 0.035906 0.000252 0.001240 0.002728 0.000271 0.005094 0.000214 0.000198 0.001729 0.003526 0.000317 0.002439
Peroxisomes 0.000920 0.000342 0.000026 0.000294 0.000242 0.001594 0.000326 0.000052 0.000270 0.001189 0.000296 0.000267
Vacuole 0.010092 0.005469 0.012432 0.027838 0.001966 0.021507 0.010673 0.017323 0.002299 0.016314 0.010850 0.026638
Vacuole Periphery 0.003017 0.003347 0.001169 0.003226 0.001289 0.006566 0.001961 0.004162 0.001359 0.005524 0.001881 0.003333

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.64 1.25 -1.70 1.01 -3.95 -4.16 -0.62 1.01 4.61 1.30 -4.14 -0.49 -2.97 2.30 -2.02
Bud Neck 1.41 -1.50 -1.81 -9.54 0.35 -6.64 -3.61 -3.00 -2.67 -2.87 -5.60 -4.19 -8.59 -7.10 -6.85
Bud Site 0.88 1.25 0.05 -3.59 -5.93 -4.64 -1.39 -1.90 -0.58 -1.59 -3.91 -0.72 -6.24 -3.36 -5.88
Cell Periphery 0.45 -0.19 -2.02 -3.70 -1.55 -1.62 -4.98 -5.11 -3.15 -2.04 -1.90 -5.05 -8.09 -3.16 -0.57
Cytoplasm 0.77 0.87 -4.43 -8.71 -7.69 -11.35 -0.76 4.16 13.49 5.38 -10.05 -0.42 -8.03 -1.05 -7.96
Cytoplasmic Foci 1.62 2.11 1.03 -3.02 -5.44 -11.51 3.11 3.10 13.06 0.81 -10.18 3.70 -4.05 6.36 -7.59
Eisosomes -0.27 1.05 -1.08 -0.52 -2.45 -3.30 -0.72 -0.72 2.44 -0.06 -3.22 -0.64 -2.26 1.94 -1.12
Endoplasmic Reticulum -2.14 -0.74 2.38 17.33 8.28 30.36* 2.42 3.64 -10.88 2.97 25.21 2.78 21.60 -0.10 20.24
Endosome 0.55 0.65 -1.13 -7.52 -6.97 -15.15 -2.36 -3.11 4.91 -2.44 -14.43 -2.26 -13.78 -0.11 -12.76
Golgi 0.28 1.16 -0.51 -2.54 -6.41 -10.38 -2.39 -0.69 9.33 1.20 -9.93 -1.80 -5.92 3.94 -4.72
Lipid Particles 0.99 0.77 -2.09 -11.97 -9.08 -11.97 -3.73 -2.43 1.94 -1.85 -10.87 -3.06 -11.65 -3.34 -10.32
Mitochondria 1.10 1.10 1.05 -1.13 -0.78 -6.77 3.02 3.81 8.78 2.07 -4.20 2.55 1.01 6.28 -2.61
Mitotic Spindle -0.44 0.81 -4.78 -3.91 -5.88 -4.81 -1.58 -1.94 0.52 -1.84 -4.70 -1.36 -6.36 -3.42 -6.24
None -2.05 2.00 -3.26 -1.32 -3.63 -4.41 1.45 3.53 5.80 2.63 -4.05 1.63 -0.65 3.24 -1.90
Nuclear Periphery -4.58 -6.94 -8.55 -6.74 4.91 -11.28 5.12 -0.69 7.08 -1.78 -10.53 -0.99 -4.82 6.30 -4.07
Nuclear Periphery Foci -3.38 -6.83 -15.48 -13.02 -3.03 -16.01* 2.06 -1.00 9.54 -1.65 -14.74 -0.47 -13.54 -0.88 -13.60
Nucleolus 1.90 1.99 1.24 -2.04 -2.40 -4.04 2.33 0.34 4.06 -0.85 -3.64 2.48 -1.95 0.87 -2.40
Nucleus 1.86 1.80 1.71 -4.99 -1.35 -6.11 0.59 -0.15 6.04 -0.44 -1.83 1.71 -1.09 1.01 -4.74
Peroxisomes 1.66 2.57 1.89 0.20 -3.33 -6.47 -0.53 3.85 7.43 1.81 -5.79 -0.11 0.08 5.51 0.15
Vacuole 1.21 0.03 -2.96 -10.17 -5.27 -10.23 -9.20 -3.46 0.39 -1.61 -10.08 -9.10 -12.80 -5.58 -8.17
Vacuole Periphery -0.23 1.26 -0.17 0.14 -4.32 -7.92 -2.31 -1.45 1.13 -1.08 -7.75 -1.93 -4.35 3.38 -3.04
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description ER membrane protein involved in a late step of GPI anchor assembly; involved in the addition of phosphoethanolamine to the multiply mannosylated glycosylphosphatidylinositol (GPI) intermediate; human PIG-Fp is a functional homolog
Localization
Cell Percentages ER (98%)
Cell Cycle Regulation No
Subcompartmental Group ER-5

Gpi11

Gpi11


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Gpi11-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available