Standard name
Human Ortholog
Description Protein integral to the mitochondrial membrane; has a conserved methyltransferase motif and is predicted to be an RNA methyltransferase; multicopy suppressor of respiratory defects caused by OXA1 mutations
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Bud 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0.06 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0.12 0.12 0.07 0 0 0 0 0 0
Cytoplasm 0 0 0.05 0.05 0.08 0.05 0.05 0 0 0 0.06 0 0.05 0 0.1 0.08 0.07 0.09 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.07 0.1 0 0.08 0.05 0 0.06 0 0.06 0.08
Golgi 0 0.06 0 0 0 0 0 0 0 0 0 0 0.1 0.06 0.14 0.17 0.37 0.33 0.05 0.1 0.05 0.07 0.06 0.06
Mitochondria 0.96 0.82 0.9 0.93 0.87 0.87 0.89 0.92 0.94 0.96 0.92 0.97 0.8 0.81 0.6 0.12 0.18 0.12 0.77 0.66 0.69 0.75 0.68 0.6
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0.08 0.08 0.07 0 0.06 0.06 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0.1 0.06 0.05 0.08 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.08 0 0.1 0 0 0.12 0 0.05 0.05
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.13 0.08 0.08 0 0 0 0 0 0
Vac/Vac Membrane 0.11 0.15 0.07 0.05 0.08 0.05 0.06 0.05 0.07 0 0 0 0.13 0.17 0.23 0.23 0.27 0.21 0.05 0.08 0 0 0 0.07
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 0 0 0 0 1 0 0 0 0 0 1 0 1 1 3 5 1 3 4 1 10 16
Bud 1 1 7 5 2 3 6 8 5 9 2 11 4 4 1 14 3 7 0 1 0 0 3 5
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 7
Bud Site 1 0 0 0 1 2 1 4 5 6 4 2 0 0 0 2 0 2 – – – – – –
Cell Periphery 0 3 6 4 3 2 2 3 1 11 2 2 10 11 7 29 23 12 0 0 0 0 1 3
Cytoplasm 1 1 8 7 12 11 13 10 8 4 12 5 11 15 30 21 14 14 0 0 1 2 1 0
Endoplasmic Reticulum 0 3 3 1 1 7 2 0 2 1 1 2 6 5 10 18 5 6 0 0 3 0 1 3
Endosome 4 2 2 1 1 1 4 3 1 1 1 0 1 30 22 24 7 13 8 5 10 7 22 27
Golgi 0 5 3 4 3 1 1 0 0 0 0 0 21 22 43 42 74 54 7 12 9 12 23 22
Mitochondria 151 64 155 128 135 197 250 304 218 269 199 220 168 313 180 31 36 19 123 78 122 135 242 215
Nucleus 4 1 1 1 1 3 2 5 3 6 3 1 1 0 0 10 2 7 0 0 0 0 2 0
Nuclear Periphery 4 0 1 0 3 17 23 23 7 17 14 20 2 1 1 2 4 0 1 0 0 3 3 3
Nucleolus 5 1 5 2 5 23 17 15 19 11 10 7 1 1 0 1 0 1 0 0 0 0 2 1
Peroxisomes 3 0 4 1 1 0 1 1 0 0 0 1 1 21 12 21 5 17 4 4 20 6 18 19
SpindlePole 0 0 2 0 2 1 2 4 3 5 0 1 1 2 0 32 16 13 1 0 0 1 2 1
Vac/Vac Membrane 17 12 12 7 13 12 17 17 17 10 8 1 28 64 68 58 53 34 8 9 1 4 15 26
Unique Cell Count 157 78 172 137 156 226 281 331 232 280 217 227 209 387 302 249 198 162 160 120 177 180 358 359
Labelled Cell Count 191 94 209 161 183 280 342 397 289 350 256 273 256 489 375 306 246 204 160 120 177 180 358 359


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.1 6.1 5.8 6.1 6.2 5.7 5.1 5.3 5.0 4.3 4.7 4.5 6.5 6.2 6.3 6.3 7.5 7.4 5.7 6.0 6.5
Std Deviation (1e-4) 0.7 1.1 1.5 1.6 1.5 1.7 1.4 1.5 1.6 1.2 1.3 1.2 1.1 1.3 1.3 1.2 1.3 1.4 1.1 1.6 1.4
Intensity Change (Log2) – – – 0.07 0.1 -0.02 -0.19 -0.14 -0.22 -0.45 -0.31 -0.37 0.16 0.1 0.12 0.11 0.36 0.35 -0.03 0.05 0.16

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud -0.2 0 0 0 -1.0 -1.1 0 0 0 0 0 0 0.7 0 0.1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0.6 -0.4 0 3.0 2.9 1.6
Cytoplasm 0.2 1.1 0.1 0 -0.9 -0.6 0 0.4 -1.4 0.3 -0.4 2.0 1.5 1.0 1.5
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 2.5 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 3.1 2.9 3.6 0 3.0
Golgi 0 0 0 0 0 0 0 0 0 3.3 2.1 4.4 4.9 8.4 7.7
Mitochondria 1.0 -1.0 -0.9 -0.4 0.7 1.4 0 0 0 -2.6 -2.7 -7.0 -15.8 -13.8 -14.3
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 3.3 3.5 3.2 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 2.8 1.5 0.9 2.2 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 1.6 1.0 2.6 0 3.1
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 4.3 3.1 3.0
Vacuole -0.7 0.5 -0.7 -0.4 -0.8 0.1 -1.6 -1.5 -3.6 2.0 3.0 4.3 4.4 5.0 3.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.7496 3.2975 2.9463 2.2651 2.7503 2.9724 4.5963 4.6904 4.6132 4.6908 4.4779 4.3525 6.5334 6.2709 6.0141 6.3205 5.6016 5.685
Actin 0.0285 0.0053 0.0254 0.009 0.0016 0.0038 0.0596 0.0086 0.0159 0.0343 0.0007 0.0101 0.0239 0.0141 0.0247 0.0397 0.0064 0.0085
Bud 0.0008 0.0007 0.007 0.0012 0.0003 0.0002 0.001 0.0011 0.0007 0.0004 0.0004 0.0004 0.0009 0.0012 0.003 0.0004 0.0003 0.0005
Bud Neck 0.0011 0.0003 0.0006 0.0059 0.0001 0.0033 0.0011 0.0007 0.0006 0.0031 0 0.0013 0.004 0.001 0.0013 0.0006 0.0002 0.0004
Bud Periphery 0.0021 0.0015 0.007 0.0034 0.0014 0.0006 0.0024 0.002 0.0017 0.0022 0.0022 0.0008 0.0017 0.0025 0.004 0.0038 0.0008 0.0007
Bud Site 0.0064 0.0026 0.0098 0.001 0.0003 0.0006 0.0054 0.0067 0.0021 0.0008 0.0001 0.0009 0.0044 0.0344 0.0158 0.0018 0.0004 0.0006
Cell Periphery 0.0009 0.0005 0.0022 0.0004 0.0003 0.0003 0.0008 0.0007 0.013 0.0012 0.0004 0.0002 0.0009 0.0023 0.0019 0.0049 0.0001 0.0003
Cytoplasm 0.0024 0.0012 0.0013 0.0004 0.0004 0.0007 0.0051 0.0031 0.0018 0.0014 0.0015 0.0016 0.0082 0.0038 0.0042 0.0231 0.0002 0.0039
Cytoplasmic Foci 0.0172 0.0179 0.0063 0.0075 0.0132 0.0132 0.0245 0.027 0.0237 0.0052 0.0083 0.0122 0.031 0.0219 0.0243 0.0037 0.0099 0.0194
Eisosomes 0.0007 0.0002 0.0017 0.0005 0.0002 0.0006 0.0007 0.0002 0.0019 0.0073 0.0003 0.0002 0.0005 0.001 0.001 0.001 0.0001 0.0002
Endoplasmic Reticulum 0.0037 0.0004 0.0004 0.0001 0.0003 0.0002 0.0032 0.0007 0.001 0.0002 0.0014 0.0005 0.0089 0.0014 0.0016 0.0136 0.0002 0.0004
Endosome 0.0706 0.0563 0.0134 0.0058 0.0687 0.0249 0.0995 0.0842 0.035 0.0258 0.0537 0.0223 0.0794 0.0393 0.0595 0.0098 0.0288 0.0358
Golgi 0.047 0.0423 0.027 0.0114 0.0544 0.0212 0.0738 0.0628 0.0423 0.0364 0.0547 0.0419 0.0595 0.0487 0.0541 0.0068 0.053 0.0495
Lipid Particles 0.0398 0.0258 0.0059 0.0055 0.0172 0.0231 0.0416 0.022 0.0063 0.0014 0.0019 0.0056 0.0379 0.0112 0.0165 0.0015 0.0047 0.0147
Mitochondria 0.7167 0.7874 0.8603 0.9126 0.8222 0.861 0.6069 0.7392 0.8186 0.8704 0.8477 0.8644 0.6372 0.7704 0.7446 0.8534 0.8589 0.8249
None 0.0089 0.0002 0.0038 0.0005 0.0003 0.0015 0.0048 0.0008 0.0011 0.0012 0.002 0.0048 0.007 0.0118 0.0034 0.0105 0.0001 0.0013
Nuclear Periphery 0.0082 0.0003 0.0003 0 0.0002 0.0004 0.0147 0.0002 0.0003 0 0.0008 0.0021 0.012 0.0004 0.0011 0.0044 0 0.0002
Nucleolus 0.0012 0.0006 0.0002 0.0002 0.0001 0.0011 0.0027 0.0008 0.0002 0.0001 0.0001 0.0002 0.0007 0.0016 0.0009 0.0002 0.0001 0.0002
Nucleus 0.0015 0.0004 0.0003 0.0001 0.0001 0.0003 0.0027 0.0005 0.0003 0.0001 0.0001 0.0031 0.0099 0.0008 0.0006 0.0015 0.0001 0.0002
Peroxisomes 0.0247 0.0262 0.0234 0.0325 0.0134 0.033 0.0254 0.0202 0.0209 0.005 0.0051 0.0166 0.0534 0.0167 0.0186 0.0144 0.0332 0.0294
Punctate Nuclear 0.0016 0.0002 0.0001 0.0001 0.0002 0.0036 0.0052 0.0002 0.0003 0 0 0.0003 0.0034 0.0003 0.0044 0.0014 0 0.0002
Vacuole 0.0088 0.0181 0.0014 0.0008 0.0021 0.0034 0.0122 0.0135 0.0092 0.0014 0.0078 0.0067 0.0094 0.0107 0.009 0.0018 0.0008 0.0038
Vacuole Periphery 0.0071 0.0114 0.0022 0.0011 0.003 0.003 0.0066 0.0047 0.0031 0.0021 0.0105 0.0039 0.0058 0.0045 0.0053 0.0016 0.0017 0.0051

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 10.5197 13.2353 8.2704 10.0461 13.1342 10.9033 9.5084 12.835 12.2829 11.2271
Translational Efficiency 0.9554 0.6104 1.002 1.1476 0.5079 0.8402 1.1745 0.8518 0.8916 0.9021

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2508 1441 2231 1623 751 1855 182 251 3259 3296 2413 1874

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 734.93 821.73 908.42 895.70 702.27 797.64 1046.52 986.65 727.40 808.17 918.84 907.88
Standard Deviation 85.21 119.11 112.37 109.82 94.00 117.76 93.55 127.25 88.39 118.96 116.90 116.50
Intensity Change Log 2 — 0.161058 0.305753 0.285409 — 0.183712 0.575502 0.490513 — 0.172172 0.443863 0.389274

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000242 0.001020 0.000611 0.027921 0.000398 0.000479 0.021288 0.017559 0.000278 0.000715 0.002170 0.026533
Bud Neck 0.014664 0.001768 0.005694 0.008017 0.007170 0.003436 0.018813 0.011711 0.012937 0.002707 0.006683 0.008512
Bud Site 0.019841 0.012654 0.018810 0.149621 0.008983 0.010176 0.111014 0.164869 0.017339 0.011259 0.025764 0.151663
Cell Periphery 0.000368 0.000399 0.000120 0.000845 0.000371 0.000346 0.000769 0.000461 0.000369 0.000370 0.000169 0.000794
Cytoplasm 0.012552 0.002477 0.007257 0.042766 0.007726 0.002103 0.035710 0.054310 0.011440 0.002267 0.009403 0.044312
Cytoplasmic Foci 0.063678 0.030128 0.044793 0.090942 0.048658 0.024017 0.190133 0.156304 0.060217 0.026688 0.055755 0.099696
Eisosomes 0.000082 0.000056 0.000042 0.000179 0.000075 0.000047 0.000188 0.000134 0.000080 0.000050 0.000053 0.000173
Endoplasmic Reticulum 0.001512 0.000384 0.000994 0.002107 0.000738 0.000365 0.007124 0.002127 0.001334 0.000374 0.001457 0.002109
Endosome 0.099004 0.071443 0.083282 0.072014 0.065314 0.063888 0.151503 0.094336 0.091240 0.067191 0.088427 0.075004
Golgi 0.099590 0.091688 0.088576 0.120788 0.087479 0.078884 0.081286 0.105257 0.096799 0.084482 0.088026 0.118708
Lipid Particles 0.007025 0.001187 0.000770 0.000711 0.006328 0.001195 0.009440 0.003988 0.006865 0.001192 0.001424 0.001150
Mitochondria 0.557814 0.712228 0.475673 0.295072 0.669768 0.737593 0.025489 0.117120 0.583612 0.726504 0.441718 0.271237
Mitotic Spindle 0.010437 0.011955 0.062021 0.044707 0.014735 0.007509 0.085279 0.080319 0.011428 0.009453 0.063775 0.049476
None 0.002382 0.000296 0.000416 0.000318 0.000787 0.000680 0.000697 0.000214 0.002015 0.000512 0.000437 0.000304
Nuclear Periphery 0.000411 0.000173 0.000855 0.000118 0.000643 0.000087 0.001107 0.000089 0.000465 0.000125 0.000874 0.000114
Nuclear Periphery Foci 0.000463 0.000303 0.000683 0.000233 0.000387 0.000152 0.002979 0.000820 0.000445 0.000218 0.000856 0.000312
Nucleolus 0.002101 0.000607 0.001446 0.000155 0.002812 0.001033 0.004881 0.000192 0.002265 0.000846 0.001705 0.000160
Nucleus 0.002522 0.000909 0.003299 0.000975 0.004199 0.000953 0.017732 0.002841 0.002909 0.000934 0.004388 0.001225
Peroxisomes 0.014265 0.020593 0.008912 0.058681 0.033052 0.012967 0.111202 0.088774 0.018594 0.016301 0.016627 0.062711
Vacuole 0.046634 0.020313 0.123562 0.062852 0.014379 0.025094 0.099086 0.082694 0.039201 0.023004 0.121716 0.065510
Vacuole Periphery 0.044413 0.019420 0.072185 0.020978 0.025998 0.028997 0.024278 0.015880 0.040169 0.024810 0.068571 0.020295

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.76 -4.54 -11.49 -11.10 -11.33 -0.75 -4.01 -4.22 -4.20 0.55 -3.19 -4.62 -12.17 -11.95 -11.09
Bud Neck 11.59 7.41 5.29 -10.67 -3.17 2.36 -2.90 -2.19 -4.51 1.51 10.53 5.82 3.94 -9.31 -2.52
Bud Site 3.56 0.33 -24.57 -25.80 -24.87 -0.64 -8.09 -12.09 -12.01 -3.01 4.12 -4.62 -27.59 -29.01 -25.19
Cell Periphery -0.57 8.29 -3.07 -2.78 -4.78 0.27 -1.46 -0.72 -0.99 0.98 -0.03 5.66 -3.13 -3.11 -4.69
Cytoplasm 8.86 3.97 -12.64 -18.08 -15.47 2.89 -4.56 -7.37 -8.59 -2.29 9.46 1.41 -14.73 -20.16 -15.84
Cytoplasmic Foci 12.68 7.32 -7.53 -18.06 -13.89 7.12 -12.09 -10.39 -13.46 2.33 16.46 1.88 -11.52 -23.75 -12.78
Eisosomes 6.98 11.83 -13.13 -17.42 -19.93 5.73 -6.15 -4.69 -7.45 2.68 10.07 8.13 -14.08 -19.72 -18.72
Endoplasmic Reticulum 5.96 2.48 -1.87 -5.75 -3.63 2.79 -4.75 -3.23 -4.17 3.47 6.66 -0.86 -2.79 -6.66 -2.28
Endosome 6.59 3.99 6.81 -0.02 3.11 0.26 -6.75 -3.18 -3.65 4.15 7.48 0.86 4.73 -2.21 3.83
Golgi 1.57 2.64 -3.69 -4.71 -5.90 1.35 0.90 -1.37 -2.44 -1.91 3.33 2.38 -4.22 -6.98 -6.07
Lipid Particles 7.17 8.72 8.87 0.99 0.31 4.31 -1.11 1.04 -1.53 1.69 8.81 8.28 8.62 0.06 0.76
Mitochondria -14.46 8.67 26.04 36.66 17.26 -4.87 48.44 31.43 42.78 -6.40 -17.89 15.69 34.24 51.24 17.25
Mitotic Spindle -0.82 -16.08 -11.20 -9.99 4.11 3.15 -5.28 -6.03 -6.78 0.14 1.61 -16.74 -12.53 -13.22 3.38
None 3.62 3.41 3.57 -0.27 1.48 0.60 0.17 2.62 1.53 1.20 3.27 3.55 3.82 1.42 1.92
Nuclear Periphery 2.11 -2.99 4.19 0.46 5.24 1.16 -0.71 1.10 -1.14 2.11 2.67 -2.35 2.76 -0.06 5.62
Nuclear Periphery Foci 1.23 -1.77 0.73 -0.27 1.86 2.20 -4.50 -0.91 -1.36 2.99 3.08 -3.33 0.18 -1.28 2.53
Nucleolus 3.60 1.55 5.87 1.71 5.00 1.68 -0.86 2.60 1.74 1.86 3.26 1.13 6.13 2.52 4.96
Nucleus 2.18 -1.58 3.78 -0.29 3.86 2.68 -2.65 -0.47 -1.69 2.11 4.08 -2.22 1.90 -1.63 3.52
Peroxisomes -2.84 4.15 -12.93 -9.90 -14.62 5.43 -5.84 -5.10 -7.37 1.39 1.49 1.21 -13.09 -13.77 -13.36
Vacuole 10.62 -19.61 -5.09 -12.37 12.13 -5.00 -8.58 -7.84 -6.70 1.17 8.65 -22.93 -8.57 -13.81 11.81
Vacuole Periphery 11.64 -9.06 10.76 -0.69 17.83 -1.00 0.52 3.07 5.08 1.87 8.58 -10.16 10.53 2.97 18.14
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein integral to the mitochondrial membrane; has a conserved methyltransferase motif and is predicted to be an RNA methyltransferase; multicopy suppressor of respiratory defects caused by OXA1 mutations
Localization
Cell Percentages mitochondrion (92%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Oms1

Oms1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Oms1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available