Standard name
Human Ortholog
Description Calmodulin-binding actin-associated protein; roles in endocytic membrane tabulation and constriction, and exocytosis; N-BAR domain protein that interacts with Rvs161p to regulate actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; recruited to bud tips by Gyl1p and Gyp5p during polarized growth; homolog of mammalian amphiphysin
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.73 0.59 – 0.3 0.38 0.25 0.29 0.4 0.39 0.39 0.14 0.4 0.47 0.43 0.49 0.47 0.62 0.61 0.78 0.72 0.34 0.52 0.25 0.16
Bud 0.23 0.24 – 0.13 0.19 0.13 0.21 0.14 0.24 0.18 0.19 0.15 0.15 0.16 0.18 0.14 0.14 0.17 0 0.08 0 0.07 0 0
Bud Neck 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.06 0 0 0
Bud Site 0.08 0 – 0 0 0 0 0.05 0 0.09 0.14 0 0.06 0 0 0 0 0 – – – – – –
Cell Periphery 0 0.09 – 0 0 0.06 0 0 0.09 0 0 0.07 0.06 0.16 0.16 0.09 0.1 0.11 0 0 0 0 0 0
Cytoplasm 0.16 0.18 – 0.43 0.4 0.49 0.38 0.3 0.18 0.15 0.14 0.16 0.41 0.42 0.28 0.36 0.29 0.17 0 0.05 0.09 0.15 0.54 0.58
Endoplasmic Reticulum 0.06 0.1 – 0.13 0.08 0.13 0.06 0.16 0.05 0.07 0.19 0 0 0.07 0.05 0 0 0 0 0 0 0 0 0
Endosome 0 0 – 0.09 0.06 0 0 0 0 0 0 0 0 0 0.08 0.06 0 0 0 0.05 0.08 0.06 0 0
Golgi 0 0 – 0 0 0 0 0 0 0 0.1 0 0 0.07 0.06 0.14 0.1 0.33 0 0 0 0 0 0
Mitochondria 0.18 0.3 – 0.13 0.13 0.23 0.28 0.36 0.45 0.56 0.48 0.53 0 0 0 0.08 0.1 0.22 0 0 0.25 0 0 0
Nucleus 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0.16 0 – 0.17 0.09 0 0.13 0.14 0.07 0.13 0.19 0.12 0 0.07 0.14 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0.05 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 115 54 – 7 32 18 34 54 40 33 3 36 55 94 116 40 13 11 149 80 12 61 47 33
Bud 36 22 – 3 16 9 25 19 24 15 4 14 17 34 42 12 3 3 7 9 1 8 4 8
Bud Neck 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 5 2 4 3 5
Bud Site 13 4 – 0 1 0 0 7 2 8 3 3 7 0 1 0 0 0 – – – – – –
Cell Periphery 7 8 – 1 3 4 3 3 9 3 0 6 7 35 39 8 2 2 1 0 0 0 3 3
Cytoplasm 26 16 – 10 34 35 45 40 18 13 3 15 47 93 66 31 6 3 5 5 3 17 101 120
Endoplasmic Reticulum 9 9 – 3 7 9 7 21 5 6 4 4 4 16 12 2 0 0 1 0 0 3 3 6
Endosome 4 0 – 2 5 1 2 6 2 1 0 0 2 3 18 5 0 0 5 5 2 6 6 5
Golgi 1 4 – 0 1 1 2 6 1 1 2 3 4 16 15 12 2 6 3 0 0 1 0 1
Mitochondria 28 27 – 3 11 16 33 49 46 48 10 48 5 1 10 7 2 4 5 0 9 1 7 4
Nucleus 1 0 – 0 0 2 3 3 0 0 0 0 0 1 2 1 0 0 0 0 0 0 0 0
Nuclear Periphery 0 1 – 0 0 1 2 1 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 1 2 – 0 0 0 1 1 1 0 0 0 2 0 2 0 0 0 0 0 0 0 0 0
Peroxisomes 26 4 – 4 8 1 15 19 7 11 4 11 5 15 34 3 0 0 4 1 0 1 0 2
SpindlePole 0 0 – 0 1 0 3 6 2 3 0 2 1 1 9 4 0 0 2 0 0 1 0 0
Vac/Vac Membrane 1 0 – 0 1 1 2 1 1 1 0 1 3 0 2 0 0 0 0 2 2 3 8 8
Unique Cell Count 158 91 23 85 71 119 135 102 85 21 91 116 219 239 86 21 18 192 113 37 118 190 208
Labelled Cell Count 268 151 33 120 98 177 236 159 143 33 144 159 309 368 125 28 29 192 113 37 118 190 208


Actin

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.2 10.4 – 7.5 7.8 7.5 7.1 6.9 7.1 7.0 6.4 6.9 11.1 11.6 11.5 13.5 15.2 16.3 10.0 10.9 12.5
Std Deviation (1e-4) 1.5 1.9 – 1.0 1.8 1.8 2.0 1.9 1.7 1.9 1.6 2.4 2.2 1.8 2.4 3.7 3.9 2.8 2.2 2.2 2.5
Intensity Change (Log2) – – – – – – – – – – – – – – – – – – – – –


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 9.8059 10.2482 9.6954 8.8982 9.4239 10.0235 6.1774 6.5023 6.199 6.1329 5.2026 6.9984 9.2661 10.7398 9.6769 9.2693 8.8923 10.0893
Actin 0.7032 0.5346 0.7163 0.7432 0.7455 0.8083 0.6944 0.4626 0.7246 0.7838 0.6812 0.8037 0.8025 0.745 0.8172 0.8925 0.8482 0.8692
Bud 0.0027 0.0048 0.0347 0.0188 0.006 0.0021 0.0009 0.0033 0.048 0.003 0.01 0.0004 0.0026 0.0033 0.0068 0.0045 0.0085 0.0005
Bud Neck 0.0103 0.0089 0.0118 0.0023 0.0214 0.0881 0.0516 0.0062 0.017 0.001 0.0015 0.0527 0.0059 0.0056 0.0087 0.0052 0.0004 0.0754
Bud Periphery 0.0042 0.0024 0.0372 0.0225 0.0042 0.0032 0.0008 0.0022 0.0576 0.0026 0.0227 0.0003 0.0023 0.0023 0.0063 0.0073 0.0307 0.0005
Bud Site 0.0204 0.1488 0.0361 0.0157 0.0042 0.0041 0.0521 0.1754 0.0354 0.0018 0.0029 0.0009 0.0188 0.0687 0.0248 0.0035 0.0021 0.0007
Cell Periphery 0.0046 0.0017 0.0008 0.0012 0.0003 0.0003 0.0016 0.0036 0.0014 0.0002 0.0005 0.0002 0.0005 0.0004 0.0007 0.0003 0.0005 0.0002
Cytoplasm 0.0574 0.1903 0.0678 0.0652 0.0774 0.03 0.014 0.3053 0.0672 0.1861 0.0271 0.0728 0.0202 0.082 0.0746 0.014 0.0397 0.0075
Cytoplasmic Foci 0.0478 0.0515 0.0334 0.0179 0.0534 0.0276 0.0903 0.0109 0.0216 0.0053 0.1143 0.0524 0.0378 0.0475 0.0171 0.0143 0.0039 0.0147
Eisosomes 0.0007 0.0002 0.0005 0.0004 0.0006 0.0004 0.0013 0.002 0.0012 0.0002 0.0002 0.0004 0.0006 0.0002 0.0003 0.0007 0.0003 0.0003
Endoplasmic Reticulum 0.0103 0.0009 0.0013 0.0045 0.0037 0.001 0.0012 0.0026 0.0006 0.0025 0.0238 0.0008 0.0015 0.0003 0.0023 0.0005 0.0155 0.002
Endosome 0.0274 0.0027 0.0084 0.0235 0.0203 0.0095 0.0053 0.003 0.0019 0.0023 0.0143 0.0017 0.0182 0.0055 0.0062 0.007 0.0089 0.0034
Golgi 0.0222 0.0088 0.0163 0.0101 0.02 0.0126 0.0048 0.0154 0.0072 0.0055 0.0151 0.0053 0.0242 0.0071 0.0055 0.0141 0.0061 0.0058
Lipid Particles 0.0118 0.0006 0.0023 0.0017 0.0113 0.001 0.0039 0.0023 0.0007 0.0005 0.0055 0.0006 0.0127 0.0003 0.0076 0.0069 0.0011 0.0015
Mitochondria 0.007 0.0007 0.0011 0.0084 0.0027 0.0009 0.0013 0.0012 0.0043 0.0016 0.0017 0.0003 0.0135 0.0003 0.0007 0.0197 0.0191 0.006
None 0.0047 0.0004 0.0026 0.0014 0.001 0.0004 0.0357 0.0006 0.0003 0.0002 0.0012 0.0001 0.0015 0.0003 0.0033 0.0004 0.0015 0.0003
Nuclear Periphery 0.0168 0.0002 0.0053 0.0104 0.0019 0.0002 0.0008 0.0002 0.0001 0.0001 0.0016 0 0.0018 0.0001 0.0003 0.0002 0.0054 0.0006
Nucleolus 0.0006 0 0.0011 0.0004 0.0001 0.0001 0.003 0.0001 0 0 0 0 0.0003 0 0.0001 0.0001 0.0001 0
Nucleus 0.0039 0.0003 0.0025 0.0039 0.0011 0.0004 0.003 0.0002 0.0001 0.0001 0.0003 0 0.0005 0.0001 0.0003 0.0001 0.0009 0.0003
Peroxisomes 0.0311 0.0415 0.0162 0.031 0.0219 0.0091 0.0075 0.002 0.0103 0.0025 0.0711 0.0069 0.0294 0.0304 0.0162 0.0075 0.0039 0.0105
Punctate Nuclear 0.0075 0.0005 0.0036 0.0013 0.0024 0.0003 0.0263 0.0003 0.0003 0.0001 0.0046 0.0004 0.0038 0.0003 0.0007 0.0004 0.0008 0.0003
Vacuole 0.0034 0.0002 0.0004 0.0103 0.0004 0.0003 0.0003 0.0003 0.0002 0.0005 0.0003 0 0.0009 0.0002 0.0002 0.0003 0.0016 0.0001
Vacuole Periphery 0.0022 0 0.0002 0.0059 0.0003 0.0001 0.0001 0.0001 0 0.0001 0.0002 0 0.0005 0 0.0001 0.0003 0.0006 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 138.5919 106.8744 133.8595 121.4682 150.5648 143.8426 106.512 108.4714 146.2208 119.3087
Translational Efficiency 1.375 1.4103 1.1545 1.4564 1.1739 1.2391 1.2677 1.5371 1.2212 1.3014

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1876 1222 257 1399 1609 1464 337 953 3485 2686 594 2352

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 967.66 966.48 1640.08 1446.98 983.28 1093.94 1561.69 1565.07 974.87 1035.95 1595.61 1494.83
Standard Deviation 134.64 187.03 212.76 246.69 145.91 160.47 248.26 280.71 140.17 184.33 236.77 267.37
Intensity Change Log 2 — -0.001760 0.761194 0.580473 — 0.153859 0.667434 0.670553 — 0.078769 0.714700 0.626576

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.555874* 0.613551* 0.607849* 0.667299* 0.747096* 0.683620* 0.632229* 0.672110* 0.644160* 0.651742* 0.621681* 0.669248*
Bud Neck 0.010940 0.005084 0.026354 0.003856 0.003572 0.004277 0.010462 0.006669 0.007538 0.004644 0.017338 0.004996
Bud Site 0.232326* 0.071187 0.227868* 0.160797* 0.103248* 0.133491* 0.127185* 0.212835* 0.172732* 0.105146* 0.170747* 0.181882*
Cell Periphery 0.001921 0.000562 0.006026 0.001112 0.001696 0.001341 0.001008 0.005567 0.001817 0.000987 0.003179 0.002917
Cytoplasm 0.039162 0.025767 0.030121 0.038198 0.018731 0.038151 0.013757 0.030253 0.029729 0.032517 0.020837 0.034979
Cytoplasmic Foci 0.058367 0.061285 0.019735 0.024037 0.026456 0.034233 0.052195 0.011229 0.043634 0.046540 0.038150 0.018847
Eisosomes 0.000801 0.000458 0.001600 0.001298 0.000734 0.000709 0.002057 0.012123 0.000770 0.000595 0.001859 0.005684
Endoplasmic Reticulum 0.000422 0.000309 0.004444 0.000710 0.000518 0.000730 0.001725 0.002018 0.000466 0.000539 0.002901 0.001240
Endosome 0.003430 0.035125 0.019059 0.022811 0.009440 0.006652 0.049246 0.010659 0.006205 0.019606 0.036185 0.017887
Golgi 0.006649 0.025288 0.011818 0.013979 0.012190 0.014055 0.014057 0.008466 0.009207 0.019165 0.013088 0.011745
Lipid Particles 0.001139 0.021856 0.020897 0.009811 0.006388 0.001371 0.036201 0.006442 0.003563 0.010690 0.029580 0.008446
Mitochondria 0.001378 0.000892 0.000249 0.003021 0.001139 0.001886 0.000129 0.001867 0.001268 0.001433 0.000181 0.002553
Mitotic Spindle 0.001047 0.000965 0.001936 0.009284 0.000519 0.002908 0.001998 0.001676 0.000803 0.002024 0.001971 0.006201
None 0.000130 0.000052 0.000025 0.000037 0.000054 0.000033 0.000019 0.000146 0.000095 0.000041 0.000021 0.000081
Nuclear Periphery 0.000002 0.000004 0.000041 0.000091 0.000002 0.000165 0.000023 0.000040 0.000002 0.000092 0.000031 0.000070
Nuclear Periphery Foci 0.000035 0.000126 0.001090 0.000641 0.000046 0.000551 0.000857 0.000316 0.000040 0.000358 0.000958 0.000509
Nucleolus 0.000040 0.000018 0.000007 0.000022 0.000007 0.000032 0.000006 0.000008 0.000025 0.000025 0.000007 0.000016
Nucleus 0.000321 0.000109 0.000857 0.000087 0.000078 0.000234 0.000139 0.000099 0.000209 0.000177 0.000449 0.000092
Peroxisomes 0.084800 0.135934* 0.010714 0.036550 0.067412 0.073621 0.041901 0.014024 0.076772 0.101970* 0.028408 0.027423
Vacuole 0.000939 0.001289 0.009116 0.005044 0.000604 0.001266 0.014677 0.002531 0.000784 0.001277 0.012271 0.004026
Vacuole Periphery 0.000278 0.000138 0.000194 0.001317 0.000069 0.000675 0.000129 0.000923 0.000182 0.000431 0.000157 0.001157

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.13 -1.35 -7.76 -3.22 -2.91 5.12 5.68 5.49 1.05 -1.96 -0.73 2.30 -1.86 -1.11 -3.30
Bud Neck 4.82 -4.99 6.87 1.49 7.67 -0.98 -3.66 -3.55 -2.63 1.95 4.01 -5.56 3.75 -0.68 7.24
Bud Site 18.98* 0.25 6.92 -10.90 3.77 -3.63 -1.98 -9.97 -7.03 -5.42 10.85 0.04 -1.51 -11.18 -1.02
Cell Periphery 8.61 -2.38 4.48 -3.88 2.87 0.76 1.60 -3.88 -4.37 -4.79 3.41 -1.71 -2.55 -4.64 0.26
Cytoplasm 3.53 -0.49 -0.61 -3.52 0.21 -5.54 -0.00 -3.64 1.51 -2.43 -1.23 0.04 -2.82 -1.50 -1.57
Cytoplasmic Foci -0.73 8.32 9.08 8.91 -0.89 -2.42 -4.39 5.41 7.44 6.84 -1.10 0.93 10.10 10.69 5.20
Eisosomes 6.05 -1.68 -1.23 -2.12 0.45 0.22 -1.03 -4.66 -4.67 -3.68 2.70 -1.42 -4.80 -4.97 -3.06
Endoplasmic Reticulum 0.83 -2.75 -1.38 -2.42 2.55 -0.51 -1.77 -2.00 -1.57 -0.36 -0.32 -3.28 -2.35 -1.86 2.03
Endosome -11.27 -5.19 -8.81 3.50 -1.07 1.98 -6.23 -0.63 -2.17 5.92 -8.99 -7.71 -7.47 0.85 4.43
Golgi -8.91 -1.93 -4.09 4.46 -0.80 -0.94 -0.60 1.87 2.53 1.89 -7.05 -1.98 -1.84 4.41 0.55
Lipid Particles -7.10 -5.19 -6.63 3.71 2.82 4.21 -4.71 -0.09 -3.34 4.62 -4.89 -6.66 -4.41 1.24 5.27
Mitochondria 1.61 4.97 -1.81 -2.37 -3.17 -1.24 3.96 -0.79 0.03 -1.96 -0.47 6.42 -1.95 -1.57 -3.76
Mitotic Spindle -0.02 -1.65 -5.03 -5.07 -4.09 -2.55 -2.48 -2.82 1.07 0.68 -2.29 -2.83 -5.47 -3.92 -3.67
None 3.15 4.12 3.51 1.11 -0.60 1.73 2.25 -0.81 -1.00 -1.10 3.69 4.66 0.29 -0.85 -1.21
Nuclear Periphery -2.33 -4.96 -1.93 -1.90 -0.80 -1.15 -5.79 -2.88 0.87 -0.96 -1.16 -7.10 -2.45 0.24 -1.13
Nuclear Periphery Foci -2.91 -3.66 -1.66 -1.40 1.72 -1.43 -2.75 -2.12 0.59 1.93 -1.65 -4.47 -2.12 -0.54 2.25
Nucleolus 0.86 0.99 0.80 -0.39 -1.76 -0.87 -0.18 -0.24 0.83 -0.10 0.47 0.98 0.76 0.57 -1.65
Nucleus 1.54 -2.02 1.58 0.14 2.87 -0.90 -1.99 -1.04 0.76 1.60 0.52 -2.03 1.46 0.78 3.06
Peroxisomes -7.15 18.34 10.36 14.65 -7.79 -1.13 4.07 12.76 13.21 4.95 -5.66 12.02 15.29 18.26 0.17
Vacuole -0.63 -4.54 -4.59 -3.98 2.49 -1.42 -3.75 -3.53 -2.06 3.25 -1.38 -5.20 -5.62 -4.50 3.79
Vacuole Periphery 1.33 0.74 -2.95 -3.51 -3.32 -1.66 -1.58 -2.58 -0.58 -2.38 -1.18 0.36 -3.96 -2.35 -4.13
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Calmodulin-binding actin-associated protein; roles in endocytic membrane tabulation and constriction, and exocytosis; N-BAR domain protein that interacts with Rvs161p to regulate actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; recruited to bud tips by Gyl1p and Gyp5p during polarized growth; homolog of mammalian amphiphysin
Localization
Cell Percentages actin (90%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Rvs167

Rvs167


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rvs167-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available