Standard name
Human Ortholog
Description RNA polymerase II subunit B16; forms dissociable heterodimer with Rpb4p; Rpb4/7 dissociates from RNAPII as Ser2 CTD phosphorylation increases; Rpb4/7 regulates cellular lifespan via mRNA decay process; involved in recruitment of 3'-end processing factors to transcribing RNA polymerase II complex, export of mRNA to cytoplasm under stress conditions; also involved in translation initiation
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Neck – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 – – – – – –
Cell Periphery – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm – 0 – 0 0.09 0.07 0.05 – 0.05 0 0 0 – 0 0.07 0.06 0 0.11 0 0 0 0 0 0
Endoplasmic Reticulum – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Endosome – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Golgi – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0.05 0 0 0 0 0
Mitochondria – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0.1 0.06 0.14 0 0 0 0 0 0
Nucleus – 0.92 – 0.75 0.74 0.72 0.77 – 0.67 0.7 0.64 0.67 – 0.75 0.67 0.61 0.67 0.43 0.46 0.74 0.36 0.43 0.43 0.39
Nuclear Periphery – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus – 0.68 – 0.6 0.3 0.54 0.34 – 0.55 0.67 0.67 0.56 – 0.59 0.52 0.53 0.31 0.55 0.46 0.23 0.54 0.51 0.5 0.51
Peroxisomes – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
SpindlePole – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0.09 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 5 3
Bud Neck – 0 – 0 0 0 0 – 0 0 0 1 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site – 0 – 0 0 1 0 – 0 0 0 1 – 1 2 0 0 0 – – – – – –
Cell Periphery – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm – 0 – 2 10 7 11 – 9 3 3 6 – 7 15 6 3 6 0 0 0 0 0 2
Endoplasmic Reticulum – 0 – 0 0 0 0 – 0 1 0 0 – 0 0 2 0 0 0 0 0 0 0 0
Endosome – 0 – 0 1 0 2 – 0 0 0 0 – 2 1 0 0 1 0 0 0 1 0 0
Golgi – 0 – 0 0 0 0 – 0 0 0 0 – 0 0 1 0 0 0 0 0 0 0 0
Mitochondria – 0 – 0 1 4 0 – 5 2 4 1 – 2 1 10 4 8 0 0 0 0 0 1
Nucleus – 23 – 41 80 72 156 – 124 134 107 119 – 117 149 62 45 24 6 52 6 55 102 69
Nuclear Periphery – 0 – 0 0 0 0 – 0 0 0 1 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus – 17 – 33 32 54 69 – 101 128 113 100 – 92 116 54 21 31 6 15 9 65 120 90
Peroxisomes – 1 – 0 0 0 0 – 0 0 0 1 – 1 3 0 1 0 0 0 0 0 0 0
SpindlePole – 1 – 0 1 0 2 – 1 0 0 0 – 1 7 0 0 1 0 0 0 0 2 1
Vac/Vac Membrane – 1 – 1 2 0 1 – 2 1 0 1 – 1 1 1 0 1 0 1 1 1 4 6
Unique Cell Count 25 55 108 100 203 185 191 168 177 157 222 101 67 56 14 70 17 128 239 178
Labelled Cell Count 43 77 127 138 241 242 269 227 231 224 295 136 74 72 14 70 17 128 239 178


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) – 24.9 – 18.8 19.5 11.0 17.9 – 15.2 15.1 14.3 15.3 – 17.5 23.6 21.5 23.5 23.7 20.2 22.3 21.9
Std Deviation (1e-4) – 6.9 – 5.6 9.1 3.9 4.8 – 6.9 4.5 3.8 5.7 – 7.1 11.4 9.9 9.3 12.4 5.9 10.6 7.9
Intensity Change (Log2) – – – – – – – – – – – – – – – – – – – – –


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 8.6393 13.7446 12.1116 12.1176 6.5842 10.8705 15.244 18.414 15.2703 15.1915 12.5399 13.9334 18.1633 18.1197 15.5534 15.8032 17.8465 16.5882
Actin 0.0215 0 0.0022 0 0.057 0.0018 0.0081 0 0.0098 0.0021 0.0002 0.0009 0.0018 0 0.0087 0 0 0.0031
Bud 0.0009 0 0.0002 0 0.001 0.0001 0.0018 0.0001 0.0009 0.0004 0.0001 0.0004 0.0002 0 0.0003 0.0001 0.0001 0.0001
Bud Neck 0.0005 0 0.0002 0.0001 0.0011 0.0002 0.0004 0 0.0002 0.0003 0.0002 0.0009 0.0002 0.0001 0.0001 0.0001 0.0001 0.0002
Bud Periphery 0.0011 0 0.0003 0 0.0024 0.0001 0.002 0 0.0011 0.0006 0.0002 0.0005 0.0003 0 0.0004 0.0001 0.0003 0.0001
Bud Site 0.002 0 0.0005 0 0.0017 0.0001 0.0079 0.0001 0.0023 0.0013 0.0002 0.0003 0.0006 0 0.0008 0.0002 0.0002 0.0001
Cell Periphery 0.0003 0 0.0002 0 0.0006 0 0.0003 0.0001 0.0001 0.0002 0.0001 0.0002 0.0001 0 0 0.0001 0.0003 0
Cytoplasm 0.0124 0 0.0004 0 0.0087 0.0022 0.0027 0.0001 0.001 0.0002 0.0087 0.0013 0.0017 0.0001 0.0002 0 0 0.0001
Cytoplasmic Foci 0.0232 0 0.0018 0 0.0127 0.0008 0.0332 0 0.0026 0.0022 0.0005 0.0055 0.0051 0 0.0026 0 0 0.0013
Eisosomes 0.0002 0 0 0 0.0006 0 0.0002 0 0.0001 0.0001 0 0 0.0001 0 0 0 0.0001 0
Endoplasmic Reticulum 0.0054 0 0.0013 0 0.0092 0.0015 0.0023 0 0.001 0.0002 0.0016 0.0009 0.0022 0 0.0002 0 0 0.0001
Endosome 0.0696 0 0.0022 0 0.0608 0.0083 0.02 0 0.0076 0.0009 0.0091 0.0174 0.0093 0 0.0013 0 0 0.0027
Golgi 0.0359 0 0.0004 0 0.0187 0.0016 0.0057 0 0.0028 0.0005 0.0001 0.0033 0.0008 0 0.0013 0 0 0.0028
Lipid Particles 0.0493 0 0.0003 0 0.0357 0.0024 0.0496 0 0.0121 0.0034 0.0001 0.0015 0.0021 0 0.0013 0 0.0002 0.0129
Mitochondria 0.0147 0.0001 0.0044 0.0002 0.0695 0.0011 0.0095 0.0004 0.0159 0.0135 0.0051 0.0017 0.0068 0.0005 0.0014 0.0008 0.0322 0.0011
None 0.0054 0 0.0003 0 0.0033 0.0003 0.0036 0 0.0008 0.0003 0.0007 0.0006 0.0015 0 0.0003 0 0 0.0001
Nuclear Periphery 0.1179 0.0002 0.0152 0.0001 0.0606 0.0263 0.029 0.0048 0.0156 0.0057 0.0178 0.0047 0.1537 0.0033 0.0047 0.0001 0.0001 0.0022
Nucleolus 0.2158 0.1544 0.188 0.1738 0.3192 0.462 0.1585 0.1344 0.1058 0.1843 0.6279 0.4877 0.2286 0.1838 0.1519 0.151 0.7758 0.4373
Nucleus 0.3625 0.845 0.7444 0.8253 0.2856 0.486 0.5816 0.8596 0.803 0.7677 0.3201 0.454 0.4707 0.8093 0.8116 0.8467 0.1892 0.5303
Peroxisomes 0.0116 0 0.0003 0 0.0088 0.0002 0.0103 0 0.0019 0.0004 0.0001 0.0004 0.0003 0 0.0011 0 0.0001 0.0024
Punctate Nuclear 0.0318 0.0001 0.0339 0.0001 0.0138 0.0029 0.0669 0.0001 0.0084 0.0136 0.0014 0.0154 0.0854 0.0025 0.0115 0.0004 0.0002 0.0026
Vacuole 0.0076 0 0.0021 0.0001 0.0191 0.0008 0.0027 0.0002 0.0036 0.0007 0.0036 0.0011 0.0045 0.0001 0.0001 0.0001 0.0003 0.0001
Vacuole Periphery 0.0104 0 0.0014 0.0001 0.01 0.0012 0.0038 0.0001 0.0036 0.0013 0.0022 0.0012 0.0241 0.0002 0.0002 0.0001 0.0007 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 40.6292 38.2316 26.951 53.0236 38.8151 29.9208 40.5888 46.3101 42.8994 56.0477
Translational Efficiency 1.9116 2.0073 2.5092 1.2978 1.6684 2.1021 2.156 1.6477 1.5881 1.4192

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
80 291 1972 61 972 70 1881 93 1052 361 3853 154

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1395.95 1860.43 1912.93 2290.50 1291.24 1666.01 1882.53 2310.30 1299.20 1822.73 1898.09 2302.46
Standard Deviation 371.30 464.35 429.25 584.43 303.20 384.12 448.05 559.75 310.15 456.43 438.79 569.74
Intensity Change Log 2 — 0.414389 0.454537 0.714415 — 0.367640 0.543916 0.839323 — 0.392114 0.498176 0.775786

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001146 0.000741 0.000922 0.001104 0.000854 0.001153 0.000687 0.000782 0.000876 0.000821 0.000807 0.000909
Bud Neck 0.005952 0.005076 0.008655 0.006137 0.005121 0.003519 0.004456 0.007148 0.005184 0.004774 0.006605 0.006748
Bud Site 0.000975 0.000523 0.001240 0.001095 0.000626 0.000710 0.000490 0.001171 0.000653 0.000559 0.000874 0.001141
Cell Periphery 0.000030 0.000025 0.000035 0.000084 0.000049 0.000066 0.000021 0.000140 0.000047 0.000033 0.000028 0.000118
Cytoplasm 0.000120 0.000068 0.000067 0.000236 0.000138 0.000095 0.000027 0.000199 0.000137 0.000073 0.000047 0.000214
Cytoplasmic Foci 0.000486 0.000435 0.000438 0.002837 0.000422 0.000496 0.000644 0.000430 0.000426 0.000447 0.000539 0.001384
Eisosomes 0.000135 0.000120 0.000199 0.000136 0.000107 0.000115 0.000178 0.000106 0.000109 0.000119 0.000189 0.000118
Endoplasmic Reticulum 0.000824 0.000168 0.000224 0.000197 0.000359 0.001032 0.000138 0.000784 0.000394 0.000336 0.000182 0.000551
Endosome 0.000028 0.000015 0.000016 0.004740 0.000023 0.000043 0.000007 0.002210 0.000024 0.000020 0.000012 0.003212
Golgi 0.000162 0.000127 0.000082 0.007095 0.000107 0.000261 0.000041 0.000950 0.000111 0.000153 0.000062 0.003384
Lipid Particles 0.000022 0.000035 0.000007 0.000011 0.000019 0.000133 0.000004 0.000023 0.000019 0.000054 0.000006 0.000019
Mitochondria 0.002206 0.001895 0.002025 0.003798 0.002087 0.001695 0.001335 0.003096 0.002096 0.001857 0.001688 0.003374
Mitotic Spindle 0.001354 0.008235 0.000633 0.000262 0.002820 0.029855 0.000175 0.006258 0.002708 0.012427 0.000409 0.003883
None 0.001216 0.000911 0.000979 0.001267 0.001173 0.001538 0.000549 0.001596 0.001176 0.001032 0.000769 0.001466
Nuclear Periphery 0.000111 0.000104 0.000067 0.000227 0.000120 0.000053 0.000025 0.000121 0.000119 0.000094 0.000047 0.000163
Nuclear Periphery Foci 0.000037 0.000102 0.000009 0.000023 0.000097 0.000113 0.000008 0.000052 0.000092 0.000104 0.000008 0.000040
Nucleolus 0.203772 0.216756 0.112879 0.130692 0.195834 0.220436* 0.138773 0.087606 0.196438 0.217469 0.125520 0.104673
Nucleus 0.751546* 0.751653* 0.857427* 0.821045* 0.778076* 0.713773* 0.841889* 0.853666* 0.776059* 0.744308* 0.849842* 0.840745*
Peroxisomes 0.029294 0.012359 0.013737 0.014330 0.010763 0.024427 0.010198 0.010147 0.012172 0.014699 0.012009 0.011804
Vacuole 0.000319 0.000157 0.000126 0.002137 0.000373 0.000198 0.000099 0.006747 0.000369 0.000165 0.000113 0.004921
Vacuole Periphery 0.000266 0.000495 0.000232 0.002544 0.000832 0.000287 0.000255 0.016769 0.000789 0.000454 0.000243 0.011135

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 4.88 2.52 0.38 -3.01 -1.26 -0.87 5.71 -0.64 0.71 -2.78 0.67 1.65 -1.59 -1.66 -2.35
Bud Neck 0.86 -4.66 -0.50 -1.11 2.42 2.09 2.90 -2.00 -2.42 -2.26 0.41 -5.89 -2.21 -2.27 -1.38
Bud Site 3.42 -1.11 -0.43 -2.16 0.34 -0.63 1.68 -1.84 -1.71 -1.98 0.75 -2.01 -2.10 -2.22 -1.70
Cell Periphery 0.93 -0.69 -1.10 -1.24 -1.02 -0.44 2.19 -1.09 -0.79 -1.47 1.09 1.71 -1.30 -1.61 -1.72
Cytoplasm 1.05 1.20 -0.56 -1.07 -1.12 0.89 2.94 -1.07 -1.55 -2.36 1.67 2.61 -1.12 -2.03 -2.44
Cytoplasmic Foci 0.28 0.19 -1.13 -1.19 -1.17 -0.26 -0.49 -0.88 -0.66 0.02 -0.07 -0.45 -1.31 -1.31 -1.14
Eisosomes 0.90 -5.45 -0.69 -1.25 2.10 -0.68 -10.25 -0.87 -0.19 4.14 -1.05 -14.16 -1.76 -0.88 4.54
Endoplasmic Reticulum 2.82 2.57 2.65 -0.87 0.79 -0.92 8.94 -1.12 0.35 -1.77 0.41 7.07 -0.66 -0.78 -1.66
Endosome 2.19 1.78 -1.00 -1.00 -1.00 -0.90 3.13 -1.23 -1.22 -1.25 0.52 2.22 -1.44 -1.44 -1.45
Golgi 1.19 3.04 -0.99 -1.00 -1.01 -1.01 6.33 -1.18 -0.90 -1.30 -0.97 4.83 -1.16 -1.14 -1.18
Lipid Particles -0.35 2.96 2.10 0.75 -0.72 -0.97 2.24 -0.42 0.92 -1.65 -1.00 2.14 -0.03 0.99 -1.71
Mitochondria 1.35 0.44 -2.50 -3.05 -2.74 1.46 6.06 -1.97 -2.47 -3.39 1.35 3.02 -3.17 -3.67 -4.13
Mitotic Spindle -1.39 1.38 1.69 2.03 2.50 -1.31 2.47 -1.04 0.87 -1.44 -1.89 2.38 -0.79 0.96 -1.38
None 0.94 0.82 0.03 -1.05 -0.92 -0.45 2.95 -1.09 -0.22 -3.10 0.67 2.09 -0.89 -1.58 -2.94
Nuclear Periphery 0.51 2.30 -0.66 -0.81 -1.15 2.76 5.70 -1.57 -2.84 -3.69 0.78 4.71 -1.42 -1.72 -2.76
Nuclear Periphery Foci -0.43 1.54 1.20 1.43 -1.48 -0.11 2.52 1.06 0.74 -1.67 -0.13 2.65 1.54 1.29 -1.95
Nucleolus -0.30 4.04 2.39 3.32 -0.83 -0.97 7.41 5.98 4.35 2.56 -1.63 9.94 6.01 6.36 1.12
Nucleus -0.28 -4.05 -1.96 -2.19 1.29 2.07 -7.70 -2.36 -3.22 0.25 2.23 -9.41 -2.79 -3.92 1.01
Peroxisomes 2.15 1.84 1.69 -1.12 -0.22 -2.86 0.51 -0.43 2.25 -0.61 -1.38 -0.48 -0.56 0.46 -0.35
Vacuole 3.59 4.25 -0.98 -1.09 -1.10 0.82 1.43 -1.21 -1.25 -1.28 1.12 1.41 -1.42 -1.50 -1.52
Vacuole Periphery -4.19 1.81 -1.08 -0.96 -1.10 1.06 1.14 -1.35 -1.41 -1.42 0.68 1.16 -1.45 -1.52 -1.56
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description RNA polymerase II subunit B16; forms dissociable heterodimer with Rpb4p; Rpb4/7 dissociates from RNAPII as Ser2 CTD phosphorylation increases; Rpb4/7 regulates cellular lifespan via mRNA decay process; involved in recruitment of 3'-end processing factors to transcribing RNA polymerase II complex, export of mRNA to cytoplasm under stress conditions; also involved in translation initiation
Localization
Cell Percentages nucleus (78%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-2

Rpb7

Rpb7


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpb7-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available