Standard name
Human Ortholog
Description Potential adenine phosphoribosyltransferase; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity; APT2 has a paralog, APT1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.97 0.99 0.99 0.98 0.93 0.92 0.88 – 0.76 0.8 0.72 0.74 0.99 0.99 1.0 0.92 0.96 0.99 0.95 0.95 0.97 0.95 0.96 0.96
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.18 0 – 0.26 0.14 0.3 0.22 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0.07 0 0.12 – 0.11 0.09 0.08 0.06 0 0 0 0.05 0.09 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 1
Bud 1 0 0 0 0 3 0 – 1 1 1 2 0 0 0 0 0 0 0 2 0 0 0 1
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 1 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 4 0 2 4 4 2 3 – 1 5 3 7 2 1 4 0 3 3 0 0 0 0 0 0
Cytoplasm 307 527 232 211 309 219 291 – 288 333 148 160 392 376 482 85 93 67 301 497 221 199 362 399
Endoplasmic Reticulum 0 2 2 0 1 0 0 – 0 3 0 2 3 2 2 1 3 2 0 1 0 0 2 2
Endosome 1 0 0 1 0 0 0 – 1 1 0 1 0 0 0 0 0 0 5 1 1 0 2 1
Golgi 0 0 1 1 0 0 0 – 0 0 0 0 0 0 0 0 1 0 2 1 0 0 1 1
Mitochondria 2 3 0 2 3 43 13 – 98 59 62 47 0 0 0 4 1 1 0 2 0 2 1 0
Nucleus 3 2 0 0 1 8 7 – 8 16 6 10 1 4 0 0 2 0 1 5 0 1 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 1 0 1 1 0 0 0 0 0 0 1 0 0 0 1 0
Nucleolus 0 0 0 0 0 0 1 – 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 1 0 0 – 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 5 3 3 6 23 2 38 – 40 38 17 12 0 0 2 5 9 0 0 2 0 1 0 5
Unique Cell Count 315 534 234 216 331 239 330 379 418 205 216 394 380 484 92 97 68 317 522 229 210 379 416
Labelled Cell Count 323 537 240 225 342 277 353 439 457 238 245 398 383 490 95 112 73 317 522 229 210 379 416


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.2 8.2 8.2 8.0 7.9 5.1 6.5 – 5.6 6.0 5.6 6.1 9.1 7.9 8.9 8.8 9.2 9.0 8.1 8.6 8.6
Std Deviation (1e-4) 1.6 1.4 1.2 1.5 1.5 1.5 1.5 – 1.1 1.5 1.3 2.1 1.6 1.5 1.4 1.6 1.7 1.6 1.5 1.7 1.7
Intensity Change (Log2) – – – -0.02 -0.04 -0.67 -0.33 – -0.55 -0.44 -0.54 -0.43 0.16 -0.05 0.12 0.11 0.18 0.14 -0.02 0.08 0.07

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm -1.3 -3.4 -3.9 -4.9 – -7.8 -7.0 -8.3 -7.9 0.5 -0.2 0.7 -3.3 -2.0 -0.5
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 6.8 3.1 – 8.5 6.0 9.1 7.5 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 3.0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 3.2 0 4.6 – 4.4 3.9 3.5 2.5 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.4287 2.5853 2.2664 1.7521 1.7144 2.1081 2.5809 3.9911 3.6498 2.8728 3.3113 3.752 5.8387 6.9733 6.5606 6.2287 6.1878 6.6161
Actin 0.0091 0.0004 0.0002 0.0147 0.0001 0.0005 0.0109 0.0031 0.0062 0.0008 0.0002 0.0033 0.0264 0.0044 0.0085 0.0081 0.0007 0.0037
Bud 0.0038 0.0003 0.0006 0.0002 0.0001 0.0002 0.0002 0.0003 0.0016 0.0002 0 0.0003 0.0011 0.0012 0.0009 0.0002 0.0003 0.0006
Bud Neck 0.001 0.0003 0.0003 0.0222 0.0003 0.0007 0.001 0.0002 0.0005 0.0005 0.0002 0.0047 0.009 0.0002 0.0012 0.0004 0.0028 0.0009
Bud Periphery 0.0008 0.0001 0.0001 0.0001 0.0001 0.0003 0.0003 0.0002 0.0009 0.0001 0 0.0004 0.0026 0.0005 0.0011 0.0001 0.0002 0.0002
Bud Site 0.0047 0.0028 0.0003 0.0019 0 0.0001 0.0005 0.0018 0.0012 0.0001 0 0.0002 0.006 0.0013 0.0057 0.0006 0.0091 0.0001
Cell Periphery 0.0002 0.0002 0.0001 0.0001 0 0 0.0001 0.0001 0.0001 0 0 0 0.0003 0.0001 0.0002 0.0001 0.0001 0
Cytoplasm 0.6813 0.8141 0.8478 0.7436 0.7843 0.8479 0.8225 0.9111 0.8723 0.9043 0.9232 0.928 0.7413 0.9242 0.8876 0.8654 0.8679 0.9273
Cytoplasmic Foci 0.0109 0.0079 0.0075 0.0222 0.0061 0.0124 0.0099 0.0068 0.0103 0.0073 0.0037 0.0073 0.0266 0.0089 0.0191 0.0224 0.0259 0.0082
Eisosomes 0.0002 0.0001 0 0.0001 0 0 0.0002 0 0 0 0 0 0.0002 0 0.0001 0.0001 0 0
Endoplasmic Reticulum 0.0031 0.0034 0.0023 0.0034 0.0006 0.0025 0.0045 0.0016 0.0026 0.0055 0.0016 0.0019 0.0024 0.0022 0.0013 0.0013 0.0028 0.0017
Endosome 0.0056 0.0041 0.0032 0.0055 0.0012 0.0039 0.0074 0.0024 0.0033 0.0046 0.0019 0.0045 0.0162 0.0025 0.0095 0.0095 0.0091 0.0022
Golgi 0.0011 0.0003 0.0001 0.0032 0.0001 0.0003 0.0014 0.0002 0.0004 0.0003 0.0001 0.0002 0.0098 0.0012 0.0061 0.0114 0.0018 0.0003
Lipid Particles 0.0014 0.0002 0.0003 0.0098 0 0 0.0022 0.0001 0.0002 0.0001 0 0 0.009 0.0005 0.0029 0.0241 0.0037 0
Mitochondria 0.0008 0.0002 0.0002 0.0005 0.0002 0.0004 0.0007 0.0002 0.0003 0.0006 0.0001 0.0003 0.0137 0.0003 0.0068 0.0126 0.0003 0.0003
None 0.2625 0.155 0.1256 0.1385 0.2034 0.1226 0.1217 0.0626 0.0849 0.0695 0.0657 0.0415 0.1153 0.0484 0.0389 0.0173 0.0474 0.0481
Nuclear Periphery 0.0017 0.0013 0.0012 0.0021 0.0004 0.0007 0.0046 0.0009 0.0016 0.0014 0.0005 0.0007 0.0016 0.0005 0.0004 0.0005 0.001 0.0006
Nucleolus 0.001 0.0002 0.0002 0.0003 0 0 0.0001 0.0001 0.0001 0 0 0 0.0003 0 0.0001 0.0001 0.0017 0
Nucleus 0.0043 0.0058 0.0054 0.0036 0.0021 0.0054 0.0044 0.0058 0.0062 0.0026 0.0018 0.0045 0.0024 0.0018 0.0019 0.0018 0.0028 0.004
Peroxisomes 0.0018 0.0001 0.0001 0.0175 0.0002 0.0004 0.0036 0.0005 0.0013 0.0001 0 0.0003 0.0122 0.0009 0.006 0.0232 0.0014 0.0009
Punctate Nuclear 0.0028 0.0016 0.0032 0.0096 0.0005 0.0008 0.0022 0.0013 0.0048 0.0013 0.0003 0.0009 0.002 0.0004 0.001 0.0005 0.0195 0.0005
Vacuole 0.0016 0.0016 0.001 0.0007 0.0003 0.0006 0.0011 0.0007 0.0009 0.0005 0.0004 0.0007 0.0014 0.0005 0.0006 0.0003 0.0014 0.0003
Vacuole Periphery 0.0003 0.0002 0.0001 0.0001 0.0001 0.0001 0.0004 0.0001 0.0001 0.0002 0.0001 0.0002 0.0004 0.0001 0.0001 0.0002 0.0002 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 39.4073 28.9048 24.1297 36.1302 49.7832 52.514 31.5089 44.382 53.4129 56.836
Translational Efficiency 1.0773 1.0973 1.0501 0.848 0.8248 0.8782 1.0167 0.65 0.6218 0.6042

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1043 798 416 98 1682 2436 1485 1419 2725 3234 1901 1517

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 832.76 953.75 1039.17 787.40 894.68 919.49 918.20 908.50 870.98 927.94 944.67 900.68
Standard Deviation 137.58 137.44 110.11 73.22 119.97 125.17 125.35 119.48 130.52 129.15 132.02 120.77
Intensity Change Log 2 — 0.195710 0.319459 -0.080804 — 0.039462 0.037437 0.022115 — 0.116900 0.180281 -0.026584

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000271 0.000285 0.000663 0.000017 0.000119 0.000672 0.000229 0.000842 0.000177 0.000576 0.000324 0.000788
Bud Neck 0.001844 0.002300 0.002380 0.002085 0.001231 0.006495 0.001081 0.002997 0.001466 0.005460 0.001365 0.002938
Bud Site 0.006865 0.010418 0.016708 0.000496 0.003463 0.010775 0.006246 0.022498 0.004765 0.010687 0.008535 0.021077
Cell Periphery 0.000141 0.000100 0.000239 0.000461 0.000073 0.000057 0.000097 0.000105 0.000099 0.000067 0.000128 0.000128
Cytoplasm 0.735301 0.759236 0.491419 0.363629 0.787684 0.750684 0.660340 0.684566 0.767634 0.752794 0.623375 0.663833
Cytoplasmic Foci 0.099913 0.096612 0.024190 0.080122 0.071167 0.071268 0.014080 0.025891 0.082169 0.077521 0.016292 0.029395
Eisosomes 0.000032 0.000021 0.000077 0.000477 0.000018 0.000027 0.000023 0.000032 0.000023 0.000026 0.000035 0.000061
Endoplasmic Reticulum 0.002075 0.001119 0.005096 0.000220 0.000998 0.000372 0.001796 0.000931 0.001411 0.000556 0.002518 0.000885
Endosome 0.006124 0.006919 0.009418 0.002267 0.002801 0.004561 0.002018 0.003040 0.004073 0.005143 0.003637 0.002990
Golgi 0.001064 0.001722 0.000186 0.000061 0.000887 0.001015 0.000252 0.001432 0.000955 0.001190 0.000237 0.001343
Lipid Particles 0.001962 0.000907 0.003376 0.002965 0.001062 0.000750 0.000775 0.000792 0.001406 0.000788 0.001344 0.000932
Mitochondria 0.001600 0.000425 0.000322 0.000189 0.000906 0.001539 0.000221 0.002597 0.001172 0.001264 0.000243 0.002442
Mitotic Spindle 0.000820 0.003281 0.001294 0.000031 0.001065 0.006535 0.003226 0.014172 0.000971 0.005732 0.002803 0.013259
None 0.004293 0.002747 0.002521 0.007835 0.004343 0.003189 0.006607 0.003762 0.004324 0.003080 0.005713 0.004025
Nuclear Periphery 0.000211 0.000118 0.001638 0.000367 0.000147 0.000142 0.000668 0.000505 0.000171 0.000136 0.000880 0.000496
Nuclear Periphery Foci 0.003358 0.002834 0.009235 0.000248 0.002095 0.000424 0.003394 0.001514 0.002578 0.001019 0.004672 0.001432
Nucleolus 0.000583 0.000189 0.000312 0.001091 0.000175 0.000355 0.000192 0.000315 0.000331 0.000314 0.000219 0.000365
Nucleus 0.066944 0.048321 0.182980 0.456693 0.086536 0.078942 0.223682 0.115901 0.079037 0.071386 0.214775 0.137916
Peroxisomes 0.000817 0.001264 0.000408 0.000441 0.000333 0.002171 0.000190 0.001237 0.000519 0.001947 0.000238 0.001186
Vacuole 0.064425 0.060599 0.247252 0.080230 0.034416 0.059485 0.074762 0.114891 0.045902 0.059760 0.112508 0.112652
Vacuole Periphery 0.001355 0.000583 0.000287 0.000075 0.000482 0.000544 0.000119 0.001979 0.000816 0.000554 0.000156 0.001856

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.52 -4.64 8.84 9.17 8.37 -1.84 -7.54 -2.27 0.56 -1.21 -1.77 -7.17 -1.81 0.48 -0.54
Bud Neck -0.77 -2.58 -0.61 0.34 1.78 -7.63 -1.20 -6.17 5.00 -5.67 -7.34 -1.63 -5.64 4.52 -4.77
Bud Site -2.78 -1.41 8.97 9.44 3.64 -6.29 -2.31 -5.79 -1.11 -3.57 -6.33 -2.18 -4.81 -0.80 -2.67
Cell Periphery 2.98 -4.78 -4.59 -5.23 -3.30 3.81 -3.80 -2.71 -6.67 1.10 5.89 -3.73 -1.70 -6.54 1.48
Cytoplasm -1.83 23.57 15.08 15.71 1.31 6.42 26.61 27.17 22.03 2.53 3.30 31.80 27.50 25.04 -0.38
Cytoplasmic Foci 0.53 19.62 2.21 1.78 -7.87 -0.18 22.13 18.18 20.46 -6.35 1.40 30.08 23.24 22.64 -7.77
Eisosomes 4.60 -10.72 -6.06 -6.21 -5.29 -5.03 -8.08 -10.55 -4.73 -3.76 -1.40 -10.66 -7.59 -7.08 -4.10
Endoplasmic Reticulum 2.62 -7.64 5.49 5.17 13.61 4.43 -6.93 -1.47 -10.79 7.58 5.38 -8.39 1.51 -7.58 12.94
Endosome -0.51 -3.13 4.62 3.38 7.40 -3.55 3.11 3.25 5.91 0.60 -2.10 2.31 7.01 7.05 5.70
Golgi -1.06 6.46 7.38 2.89 7.89 -0.46 3.30 0.97 1.36 -1.07 -0.94 5.28 1.41 1.93 -1.05
Lipid Particles 4.28 -4.64 -2.49 -4.96 0.53 1.45 0.45 0.35 -2.74 -0.26 3.88 -0.64 1.76 -4.04 4.15
Mitochondria 1.73 1.97 2.08 1.08 0.70 -1.11 1.49 -0.24 0.75 -1.60 -0.20 2.45 0.25 0.44 -1.57
Mitotic Spindle -1.75 -1.54 3.48 2.33 4.45 -4.21 -1.86 -5.69 -2.66 -4.94 -4.70 -2.30 -5.81 -2.96 -5.05
None 1.61 2.94 -0.83 -1.21 -1.40 2.43 -1.82 0.16 -2.57 2.11 2.69 -0.62 -0.42 -3.12 0.20
Nuclear Periphery 1.63 -16.65 -3.06 -5.60 14.73 -0.01 -20.66 -16.18 -17.67 -1.45 1.11 -25.06 -16.03 -18.03 3.30
Nuclear Periphery Foci 1.45 -7.85 11.14 9.58 12.79 9.52 -6.61 2.18 -7.72 8.86 9.34 -9.01 5.33 -3.06 13.23
Nucleolus 5.18 3.52 -0.85 -1.40 -1.24 -5.02 -0.74 -1.66 1.90 -1.42 0.05 3.83 0.18 0.15 -1.60
Nucleus 4.20 -13.51 -14.59 -15.29 -9.00 2.49 -27.91 -14.28 -16.16 13.92 2.86 -31.58 -18.87 -20.61 9.79
Peroxisomes -1.30 2.90 1.89 2.54 -1.12 -6.10 3.04 -0.92 4.53 -1.72 -5.84 4.40 -0.04 4.64 -1.62
Vacuole 0.16 -19.84 -1.61 -1.64 12.21 -10.24 -19.18 -28.63 -23.96 -11.39 -6.25 -24.05 -26.42 -23.69 -4.92
Vacuole Periphery 2.09 3.00 3.51 5.09 5.32 -0.30 1.96 -0.63 -0.52 -2.11 1.35 3.69 0.49 -0.39 -1.97
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Potential adenine phosphoribosyltransferase; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity; APT2 has a paralog, APT1, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (99%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Apt2

Apt2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Apt2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available