Standard name
Human Ortholog
Description Alpha1,2-mannosyltransferase of the Golgi; involved in protein mannosylation; KRE2 has a paralog, KTR6, that arose from the whole genome duplication
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0.11 0.12 0.09 – – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0.06 0.05 0 0 0 – – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0.07 0.21 0.06 0.07 0.13 0.18 0.19 0.17 0.22 0.16 0.16 0.16 0.05 0.23 0.28 – – – 0 0 0 0 0 0
Endoplasmic Reticulum 0.05 0 0 0 0 0 0 0 0 0 0 0 0.2 0.15 0.05 – – – 0 0 0 0 0 0
Endosome 0 0 0.2 0.37 0.23 0.18 0.14 0.2 0.19 0.13 0.14 0.24 0.25 0.22 0.28 – – – 0.12 0.15 0.3 0.28 0.19 0.14
Golgi 0 0 0.08 0.2 0.11 0.09 0.07 0 0 0 0 0.07 0.14 0.07 0 – – – 0.07 0 0.29 0.33 0.21 0.16
Mitochondria 0.14 0.38 0.28 0.28 0.13 0.26 0.24 0.18 0.36 0.41 0.42 0.35 0.15 0 0 – – – 0.05 0 0 0.08 0.08 0.05
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0.06 0.06 0.06 0.05 0.07 0.05 0.05 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0 0.07 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0.84 0.61 0.63 0.35 0.61 0.46 0.51 0.47 0.32 0.37 0.26 0.23 0.32 0.34 0.27 – – – 0.73 0.73 0.34 0.27 0.48 0.61
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 4 2 3 2 4 9 2 15 13 25 27 20 – – – 0 0 3 1 2 1
Bud 0 1 3 6 2 6 5 6 15 11 25 27 3 7 5 – – – 0 0 0 0 1 1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 – – – – – – – – –
Cell Periphery 0 0 2 0 1 0 0 3 3 1 5 4 2 2 1 – – – 0 0 0 0 0 0
Cytoplasm 4 21 28 21 53 73 101 112 106 69 70 79 12 53 63 – – – 0 0 0 0 1 5
Endoplasmic Reticulum 3 3 8 2 5 9 12 21 5 11 11 11 46 35 12 – – – 0 0 0 1 5 7
Endosome 1 0 92 113 96 72 72 127 90 55 61 121 59 50 63 – – – 11 17 146 81 108 78
Golgi 0 0 35 61 47 37 38 26 20 8 13 36 32 16 10 – – – 6 5 142 95 123 89
Mitochondria 8 38 124 87 53 107 127 114 172 178 185 176 34 8 10 – – – 4 5 17 23 43 25
Nucleus 0 1 1 0 0 1 1 5 4 2 1 1 0 2 2 – – – 0 0 0 0 1 1
Nuclear Periphery 1 0 3 0 2 1 5 6 1 2 2 4 3 1 0 – – – 1 0 3 1 3 1
Nucleolus 0 0 4 5 13 26 32 39 26 30 21 25 0 0 1 – – – 0 0 0 0 0 0
Peroxisomes 0 0 5 1 3 7 4 11 5 3 8 6 0 0 2 – – – 0 0 2 5 2 0
SpindlePole 0 0 6 11 4 5 12 11 13 7 10 23 12 7 16 – – – 0 0 1 0 0 0
Vac/Vac Membrane 49 62 283 108 251 186 270 300 154 160 115 119 75 77 61 – – – 69 88 167 79 275 343
Unique Cell Count 58 101 450 308 413 408 530 643 480 438 440 509 234 226 225 96 121 487 291 575 561
Labelled Cell Count 66 126 595 419 532 533 681 785 623 540 544 647 303 285 266 96 121 487 291 575 561


Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.3 6.4 7.7 9.7 10.7 9.9 9.4 9.4 9.1 8.3 8.8 8.8 7.8 7.3 6.9 – – – 9.7 9.0 9.6
Std Deviation (1e-4) 1.0 1.3 1.4 1.7 2.2 2.1 2.1 2.2 2.2 2.0 1.9 1.7 0.9 0.8 0.9 – – – 1.8 1.7 2.1
Intensity Change (Log2) – – – 0.34 0.48 0.36 0.3 0.3 0.25 0.11 0.2 0.2 0.03 -0.07 -0.15 – – – 0.34 0.24 0.32


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 3.6 3.0 6.8 7.2 6.1 – – –
Bud 0 0 0 0 0 2.7 2.2 4.3 4.1 0 0 0 – – –
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Cytoplasm 0.3 3.3 5.3 5.9 5.5 6.9 4.6 4.6 4.6 -0.6 6.5 7.8 – – –
Endoplasmic Reticulum 0 -0.7 0.4 0.5 1.5 -1.0 0.8 0.7 0.4 8.2 6.9 2.6 – – –
Endosome 4.9 1.0 -1.0 -2.9 -0.3 -0.7 -3.2 -2.6 1.2 1.4 0.5 2.2 – – –
Golgi 4.9 1.8 0.7 -0.4 -2.6 -2.3 -4.1 -3.2 -0.4 2.5 -0.3 -1.6 – – –
Mitochondria 0.2 -5.4 -0.4 -1.3 -3.9 2.7 4.1 4.5 2.3 -3.8 -7.4 -7.1 – – –
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Nucleolus 0 2.4 4.4 4.3 4.3 3.9 4.6 3.5 3.6 0 0 0 – – –
Peroxisomes 0 0 0.8 0 0.8 0 0 0.9 0.1 0 0 0 – – –
SpindlePole 2.0 0 -0.1 1.1 0.5 1.5 0.3 1.1 2.9 2.9 0 4.0 – – –
Vacuole -7.5 -0.6 -5.1 -3.8 -5.3 -9.4 -7.9 -11.0 -12.4 -7.7 -7.1 -8.8 – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 7.3461 9.2326 8.7059 6.9498 7.3772 8.4984 8.2038 10.4318 9.8245 8.6096 8.4531 9.969 9.4995 11.6953 10.16 9.4912 9.5081 10.46
Actin 0.0122 0.0013 0.0011 0.009 0.0003 0.0007 0.0206 0.0007 0.0076 0.0004 0.0122 0.0039 0.0388 0.0003 0.0078 0.0608 0.0004 0.0026
Bud 0.0001 0.0001 0.0001 0.0006 0 0.0002 0.0004 0.0001 0.0002 0.0001 0.0002 0.0007 0.0004 0.0002 0.0003 0.0002 0.0006 0.0002
Bud Neck 0.0003 0.0003 0.0002 0.0108 0.0001 0.0003 0.001 0.0002 0.0004 0.0001 0.0003 0.0004 0.0007 0.0002 0.0005 0.0003 0.0005 0.0005
Bud Periphery 0.0002 0.0002 0.0001 0.0007 0 0.0003 0.0005 0.0001 0.0003 0.0001 0.0002 0.0015 0.0005 0.0004 0.0004 0.0003 0.0017 0.0004
Bud Site 0.0002 0.0002 0.0001 0.0019 0 0.0002 0.0029 0.0001 0.0004 0.0002 0.0003 0.0003 0.0016 0.0002 0.0003 0.0005 0.0017 0.0002
Cell Periphery 0.0001 0.0001 0.0001 0.0001 0 0.0002 0.0003 0.0001 0.0002 0.0001 0.0001 0.0003 0.0004 0.0002 0.0002 0.0002 0.0013 0.0003
Cytoplasm 0.0013 0.0045 0.0021 0.0011 0.0006 0.0011 0.0021 0.002 0.0019 0.0038 0.0013 0.0009 0.0021 0.0012 0.001 0.0014 0.001 0.0008
Cytoplasmic Foci 0.0398 0.033 0.0292 0.0281 0.0306 0.0217 0.0453 0.0231 0.0256 0.0204 0.0301 0.0183 0.0229 0.0178 0.0141 0.0207 0.0207 0.0119
Eisosomes 0 0 0 0.0001 0 0 0.0002 0 0.0002 0 0.0001 0 0.0003 0 0.0001 0.0002 0 0
Endoplasmic Reticulum 0.0016 0.0022 0.0107 0.0007 0.0008 0.002 0.004 0.0035 0.0032 0.0031 0.0023 0.0029 0.0041 0.0029 0.0023 0.003 0.0013 0.0027
Endosome 0.3669 0.4576 0.4234 0.4752 0.4044 0.3947 0.3238 0.4305 0.3386 0.461 0.5178 0.334 0.3549 0.3605 0.3574 0.437 0.5384 0.3341
Golgi 0.4583 0.4108 0.4426 0.3165 0.4684 0.3715 0.4501 0.3752 0.4628 0.3077 0.2975 0.4671 0.3676 0.4001 0.4063 0.2346 0.1969 0.4375
Lipid Particles 0.037 0.0046 0.0087 0.0064 0.0052 0.0138 0.027 0.0051 0.0061 0.0052 0.0253 0.0144 0.0256 0.0067 0.0066 0.0129 0.009 0.0249
Mitochondria 0.0266 0.0086 0.0124 0.0347 0.0026 0.0158 0.0572 0.0286 0.0575 0.0355 0.0218 0.0388 0.0965 0.0378 0.0246 0.0166 0.0113 0.0277
None 0.0001 0 0 0.0001 0 0.0001 0.0003 0 0.0001 0.0113 0.0007 0.0001 0.0005 0.0001 0.0001 0.001 0.0002 0.0001
Nuclear Periphery 0.005 0.0012 0.001 0.0011 0.0011 0.0029 0.0019 0.0037 0.0036 0.0023 0.0023 0.0021 0.0014 0.0036 0.0034 0.0019 0.0015 0.002
Nucleolus 0.0001 0.0001 0.0001 0.0003 0.0001 0.0001 0.0003 0 0.0001 0.0001 0.0001 0.0001 0.0001 0.0002 0.0001 0.0001 0.0017 0.0001
Nucleus 0.0002 0.0002 0.0001 0.0002 0.0001 0.0004 0.0003 0.0002 0.0003 0.0003 0.0003 0.0002 0.0003 0.0003 0.0003 0.0002 0.0012 0.0003
Peroxisomes 0.0054 0.0007 0.0005 0.0061 0.0004 0.0006 0.0144 0.0002 0.0016 0.0012 0.0034 0.0021 0.0054 0.0004 0.0009 0.0078 0.0013 0.0004
Punctate Nuclear 0.0003 0.0001 0.0001 0.0007 0 0.0001 0.0006 0 0.0001 0.0002 0.0027 0.0001 0.0002 0 0.0001 0.0007 0.0002 0.0001
Vacuole 0.0212 0.0412 0.0329 0.0509 0.0341 0.0817 0.0192 0.0501 0.0408 0.0484 0.0267 0.0426 0.0295 0.0672 0.0683 0.0692 0.115 0.0578
Vacuole Periphery 0.0232 0.033 0.0346 0.0546 0.0508 0.0917 0.0277 0.0765 0.0486 0.0984 0.0542 0.0693 0.046 0.0996 0.1051 0.1302 0.0939 0.0954

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 249.9057 201.8768 205.9768 204.6771 207.7563 241.4695 214.6235 184.3627 203.4436 211.2997
Translational Efficiency 0.9139 0.8773 0.832 0.8172 0.7739 0.8609 0.7304 0.8863 0.8608 0.7876

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
90 663 300 947 1877 1582 762 1663 1967 2245 1062 2610

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1068.95 1038.75 1199.98 1060.70 998.34 940.79 1179.86 999.79 1001.57 969.72 1185.54 1021.89
Standard Deviation 149.51 162.72 132.67 165.62 141.02 133.74 143.92 154.99 142.19 149.74 141.12 161.60
Intensity Change Log 2 — -0.041346 0.166816 -0.011178 — -0.085659 0.241013 0.002094 — -0.062576 0.203124 -0.004753

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.004220 0.001500 0.004757 0.007664 0.000661 0.001321 0.002582 0.007249 0.000824 0.001374 0.003196 0.007400
Bud Neck 0.002870 0.000277 0.000954 0.003946 0.000340 0.000860 0.000270 0.002068 0.000456 0.000688 0.000463 0.002750
Bud Site 0.009991 0.003266 0.005819 0.030859 0.002760 0.003089 0.002107 0.020641 0.003090 0.003141 0.003155 0.024349
Cell Periphery 0.000530 0.000111 0.000072 0.000254 0.000804 0.000827 0.000051 0.000173 0.000792 0.000615 0.000057 0.000202
Cytoplasm 0.011059 0.001894 0.001440 0.037539 0.000512 0.001423 0.000975 0.029024 0.000994 0.001562 0.001106 0.032113
Cytoplasmic Foci 0.148506 0.194077* 0.331216* 0.148551 0.061200 0.079833 0.221437* 0.187425* 0.065195 0.113572 0.252448* 0.173320
Eisosomes 0.000049 0.000030 0.000029 0.000039 0.000044 0.000059 0.000022 0.000049 0.000044 0.000051 0.000024 0.000045
Endoplasmic Reticulum 0.006057 0.001277 0.000961 0.001360 0.001905 0.001925 0.000459 0.000794 0.002095 0.001734 0.000601 0.000999
Endosome 0.320163* 0.261874* 0.280990* 0.275512* 0.261739* 0.329927* 0.243458* 0.328187* 0.264412* 0.309829* 0.254060* 0.309075*
Golgi 0.035841 0.416353* 0.267104* 0.107456 0.447197* 0.325010* 0.455203* 0.259149* 0.428375* 0.351986* 0.402068* 0.204109*
Lipid Particles 0.003106 0.003593 0.008627 0.006492 0.000930 0.002032 0.004902 0.003421 0.001029 0.002493 0.005955 0.004536
Mitochondria 0.000849 0.007545 0.000404 0.005169 0.027601 0.029726 0.001600 0.006002 0.026377 0.023175 0.001262 0.005700
Mitotic Spindle 0.010220 0.001025 0.020178 0.013769 0.000110 0.000215 0.007244 0.007829 0.000573 0.000454 0.010898 0.009984
None 0.000008 0.000020 0.000004 0.000044 0.000057 0.000040 0.000007 0.000042 0.000055 0.000034 0.000006 0.000043
Nuclear Periphery 0.000316 0.000252 0.000202 0.000529 0.000055 0.000043 0.000157 0.000076 0.000066 0.000105 0.000170 0.000241
Nuclear Periphery Foci 0.001115 0.001165 0.002523 0.003561 0.000174 0.000152 0.001497 0.000451 0.000217 0.000451 0.001787 0.001580
Nucleolus 0.000273 0.000158 0.000018 0.000219 0.000028 0.000035 0.000006 0.000056 0.000039 0.000071 0.000009 0.000115
Nucleus 0.001230 0.000315 0.000036 0.000769 0.000034 0.000585 0.000011 0.000268 0.000089 0.000505 0.000018 0.000450
Peroxisomes 0.010635 0.003839 0.006358 0.014971 0.000723 0.003447 0.001460 0.008767 0.001176 0.003563 0.002844 0.011018
Vacuole 0.416910* 0.072329 0.057741 0.315315* 0.112446 0.164570 0.044487 0.122483 0.126377 0.137329 0.048231 0.192449
Vacuole Periphery 0.016051 0.029098 0.010566 0.025981 0.080682 0.054882 0.012067 0.015845 0.077725 0.047268 0.011643 0.019523

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.16 -0.24 -1.25 -3.75 -1.17 -1.99 -2.54 -5.44 -4.75 -3.23 -1.96 -3.22 -6.76 -6.05 -3.41
Bud Neck 4.81 3.66 -1.41 -10.76 -8.51 -4.32 0.78 -6.37 -4.43 -6.71 -2.08 0.09 -10.51 -9.65 -10.83
Bud Site 3.17 2.03 -7.10 -11.86 -10.87 -0.70 1.47 -10.72 -10.34 -10.99 -0.09 -0.28 -15.85 -15.48 -15.60
Cell Periphery 1.36 1.50 0.91 -2.07 -2.81 -0.07 2.50 2.08 4.19 -2.28 0.58 2.56 2.05 3.76 -3.48
Cytoplasm 2.70 3.22 -7.15 -11.57 -12.40 -2.07 -2.10 -12.86 -12.28 -12.60 -1.55 -0.36 -17.65 -16.94 -17.61
Cytoplasmic Foci -2.37 -8.32 0.15 6.29 15.36 -6.15 -24.49 -29.56 -23.25 4.71 -14.33 -31.08 -28.81 -13.70 12.56
Eisosomes 1.08 1.16 0.57 -1.46 -1.64 -2.57 5.67 -0.95 1.63 -5.81 -1.40 5.55 -0.23 1.20 -5.87
Endoplasmic Reticulum 1.46 1.59 1.46 -0.09 -1.14 -0.05 7.17 4.69 4.17 -2.61 1.06 6.17 4.00 2.64 -2.77
Endosome 1.76 1.02 1.85 0.25 1.64 -9.22 2.32 -8.50 0.74 -9.46 -6.95 1.38 -5.62 1.44 -6.45
Golgi -29.70* -15.27 -6.34 28.07 12.05 13.09 -0.62 21.20 7.72 17.76* 8.90 2.61 28.44 21.02 21.81*
Lipid Particles -0.35 -3.24 -2.25 -1.78 0.83 -2.61 -5.77 -5.15 -2.35 1.66 -3.27 -7.48 -5.92 -2.97 1.37
Mitochondria -4.93 1.46 -3.01 1.45 -3.37 -0.81 15.17 11.56 10.76 -4.48 1.47 15.52 11.93 10.58 -5.40
Mitotic Spindle 1.03 -0.79 -0.38 -5.95 0.84 -1.66 -4.49 -6.76 -6.67 -0.41 0.37 -5.18 -8.20 -8.93 0.13
None -1.55 1.62 -2.48 -1.69 -2.97 0.70 4.15 0.46 -0.27 -2.83 1.11 4.24 0.38 -0.78 -3.93
Nuclear Periphery 0.46 1.31 -0.97 -1.16 -1.52 1.67 -3.59 -2.07 -2.90 2.38 -0.81 -4.27 -2.15 -1.59 -1.04
Nuclear Periphery Foci 0.03 -2.21 -1.98 -1.88 -0.96 0.77 -3.00 -2.72 -2.87 2.25 -1.30 -4.56 -3.16 -2.48 0.19
Nucleolus 0.40 1.93 0.11 -0.40 -5.16 -1.12 5.84 -4.43 -3.10 -8.17 -0.83 3.97 -4.95 -0.97 -6.93
Nucleus 1.62 2.51 -0.29 -2.92 -5.54 -1.28 4.86 -5.16 0.58 -5.55 -1.36 2.99 -6.21 -0.74 -7.10
Peroxisomes 1.64 0.94 -1.04 -5.78 -3.47 -4.70 -3.52 -8.59 -4.91 -7.66 -4.41 -2.97 -11.58 -7.63 -8.25
Vacuole 9.27 9.65 2.43 -20.70 -21.88 -6.42 11.26 -2.07 4.35 -12.28 -1.47 13.16 -10.18 -8.45 -23.62
Vacuole Periphery -3.04 1.44 -2.32 1.31 -5.42 6.88 21.76 21.29 15.23 -2.26 8.99 22.34 20.03 13.23 -5.16
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Alpha1,2-mannosyltransferase of the Golgi; involved in protein mannosylation; KRE2 has a paralog, KTR6, that arose from the whole genome duplication
Localization
Cell Percentages Golgi (21%), vacuole (15%), mixed (44%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Kre2

Kre2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Kre2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available