Standard name
Human Ortholog
Description Ferulic acid decarboxylase; involved in the decarboxylation of aromatic carboxylic acids such as phenylacrylic (cinnamic) acid, ferulic acid and coumaric acid and formation of the corresponding vinyl derivatives; overexpression of both Pad1p and Fdc1p increases decarboxylase activity due to the Pad1p-catalyzed formation of a diffusible cofactor required for Fdc1p activity; homolog of E. coli UbiD; GFP-fusion protein localizes to the cytoplasm in an HTP study
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0.06
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0.99 0.98 0.97 0.98 0.96 0.88 0.84 0.76 0.72 0.67 0.67 0.62 0.98 0.99 0.98 – – – 0.92 0.87 0.87 0.9 0.9 0.83
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.15 0.17 0.21 0.31 0.39 0.35 0.46 0 0 0 – – – 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0.07 0.06 0.08 0.06 0.06 0.08 0.08 0 0 0 – – – 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 1 1 1 0 0 0 1 0 – – – 1 1 1 0 1 1
Bud 0 4 0 0 0 0 3 4 3 5 3 3 1 1 0 – – – 3 16 3 0 3 15
Bud Neck 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 – – – 0 0 0 0 0 1
Bud Site 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 – – – – – – – – –
Cell Periphery 0 2 2 0 1 3 4 6 7 5 4 10 1 2 4 – – – 0 0 0 0 0 0
Cytoplasm 192 392 219 140 237 323 387 355 291 319 206 197 187 393 471 – – – 170 352 206 88 213 229
Endoplasmic Reticulum 0 0 2 0 1 1 1 7 12 14 7 0 0 1 2 – – – 0 1 4 2 2 4
Endosome 0 0 0 0 0 0 2 2 0 0 0 0 0 2 1 – – – 0 4 2 0 0 1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 2 0 0 0 1
Mitochondria 8 6 2 4 7 55 79 97 124 187 109 147 1 1 1 – – – 2 4 4 0 2 3
Nucleus 0 2 4 1 0 0 1 9 10 6 4 7 3 1 4 – – – 0 0 0 0 0 0
Nuclear Periphery 0 0 1 0 0 0 1 1 0 5 3 1 0 0 0 – – – 0 0 0 0 1 0
Nucleolus 0 0 0 0 0 0 1 1 0 0 0 1 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 2 1 0 1 1 0 0 0 0 – – – 1 8 0 0 0 1
Vac/Vac Membrane 0 2 0 4 9 24 30 36 23 29 24 25 0 3 3 – – – 0 6 7 3 6 9
Unique Cell Count 194 400 226 143 247 367 462 469 404 476 308 318 190 398 480 186 405 238 98 237 277
Labelled Cell Count 200 408 230 149 255 406 511 521 471 573 362 391 193 405 486 186 405 238 98 237 277


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.9 7.3 7.1 7.5 7.8 6.9 6.4 6.5 6.1 5.7 5.9 5.5 8.8 9.0 8.8 – – – 7.5 8.3 9.0
Std Deviation (1e-4) 2.0 2.5 2.1 2.1 2.5 2.2 2.4 2.1 2.0 2.0 2.0 2.0 2.6 2.6 2.7 – – – 2.5 2.6 2.7
Intensity Change (Log2) – – – 0.08 0.13 -0.05 -0.15 -0.13 -0.21 -0.31 -0.27 -0.36 0.31 0.35 0.3 – – – 0.08 0.23 0.34


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Bud 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Cytoplasm 0.6 -0.6 -3.8 -5.0 -6.9 -7.6 -8.7 -8.5 -9.5 1.0 1.6 1.0 – – –
Endoplasmic Reticulum 0 0 0 0 0 1.7 1.7 0 0 0 0 0 – – –
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Mitochondria 0 0 5.7 6.2 7.0 9.0 10.7 9.7 11.7 0 0 0 – – –
Nucleus 0 0 0 0 0 0.6 0 0 0 0 0 0 – – –
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 – – –
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Vacuole 0 0 3.9 3.9 4.3 3.7 3.8 4.3 4.3 0 0 0 – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.9207 2.8818 2.1312 2.3309 1.9098 2.2369 2.8731 4.5713 3.105 2.6233 2.28 3.0067 4.1595 5.5812 4.5698 5.9661 3.985 4.8308
Actin 0.0118 0.0005 0.0008 0.0005 0.0001 0.002 0.0331 0.0007 0.0076 0.0083 0.0108 0.0175 0.0111 0.0009 0.0298 0.0006 0.0013 0.0163
Bud 0.0002 0.0001 0.0019 0.0004 0 0.0002 0.0009 0.0002 0.0015 0.0061 0.0004 0.0026 0.0007 0.0007 0.0008 0.0006 0.0013 0.0005
Bud Neck 0.0011 0.0002 0.0029 0.0004 0.0002 0.0011 0.0009 0.0001 0.0002 0.0005 0.0005 0.0013 0.0012 0.0003 0.0034 0.0003 0.0004 0.0008
Bud Periphery 0.0001 0.0001 0.0028 0.0005 0 0.0002 0.0014 0.0002 0.0007 0.0079 0.0004 0.0014 0.0025 0.0004 0.0014 0.0043 0.0049 0.0004
Bud Site 0.0009 0.0005 0.0051 0.0002 0 0.0001 0.0016 0.0006 0.0061 0.0018 0.0005 0.0003 0.0058 0.0028 0.0009 0.0001 0.0001 0.0005
Cell Periphery 0.0001 0.0002 0.0004 0.0001 0 0.0001 0.0002 0.0001 0.0001 0.0004 0.0001 0.0001 0.0005 0.0001 0.0003 0.0001 0.0002 0
Cytoplasm 0.7092 0.7699 0.7591 0.7797 0.6928 0.7485 0.5234 0.715 0.5462 0.4869 0.5699 0.5757 0.739 0.8099 0.708 0.7607 0.6301 0.7554
Cytoplasmic Foci 0.0057 0.0056 0.0082 0.0035 0.0036 0.0059 0.03 0.0123 0.0056 0.008 0.0244 0.0066 0.0267 0.0087 0.0112 0.003 0.0042 0.0134
Eisosomes 0.0001 0.0003 0.0002 0 0 0.0001 0.0004 0 0.0002 0.0002 0.0001 0.0002 0.0002 0.0001 0.0003 0.0001 0.0001 0
Endoplasmic Reticulum 0.0044 0.0089 0.0041 0.0065 0.0039 0.0052 0.0043 0.0015 0.0018 0.0037 0.0025 0.0017 0.0066 0.0028 0.0094 0.0006 0.0023 0.0024
Endosome 0.004 0.0026 0.0023 0.0014 0.0013 0.0064 0.0144 0.0018 0.0038 0.0022 0.0031 0.0027 0.0104 0.0012 0.0049 0.0012 0.0008 0.0037
Golgi 0.002 0.0005 0.0004 0.0001 0.0001 0.0005 0.0079 0.0003 0.0015 0.0007 0.0024 0.0021 0.0019 0.0002 0.0024 0.0001 0.0001 0.0035
Lipid Particles 0.0019 0.0052 0.0008 0.0002 0.0006 0.0008 0.0061 0.0001 0.0036 0.0208 0.0044 0.0028 0.0032 0.0001 0.0102 0 0.0002 0.0071
Mitochondria 0.0003 0.0004 0.0005 0.0003 0.0001 0.0011 0.0072 0.0002 0.0005 0.0017 0.0284 0.0008 0.0006 0.0005 0.0012 0.0006 0.0004 0.0015
None 0.2416 0.1961 0.2028 0.1891 0.2917 0.2017 0.3311 0.2631 0.4086 0.4128 0.3369 0.3683 0.1627 0.1546 0.1749 0.2143 0.341 0.1682
Nuclear Periphery 0.003 0.0024 0.0012 0.0041 0.0012 0.0043 0.0046 0.0005 0.0021 0.0029 0.0008 0.0014 0.0028 0.0013 0.0048 0.0011 0.0016 0.0008
Nucleolus 0.0002 0.0001 0.0002 0.0001 0 0.0009 0.0003 0 0.0001 0.0106 0.0002 0.0001 0.0013 0.0001 0.0003 0 0.0001 0
Nucleus 0.0059 0.0038 0.0028 0.0093 0.003 0.0108 0.0051 0.0015 0.0035 0.0142 0.0019 0.0037 0.0042 0.0126 0.0149 0.0111 0.0089 0.0025
Peroxisomes 0.0011 0.0003 0.0003 0.0002 0.0001 0.0002 0.022 0.0005 0.0039 0.0039 0.0098 0.0075 0.0108 0.0003 0.0183 0.0001 0.0002 0.0195
Punctate Nuclear 0.0035 0.0004 0.0008 0.0009 0.0006 0.0075 0.0036 0.0007 0.0016 0.0035 0.0012 0.0024 0.0061 0.0015 0.0016 0.0005 0.0007 0.0029
Vacuole 0.0024 0.0016 0.0021 0.0021 0.0004 0.0018 0.0011 0.0004 0.0006 0.0025 0.0009 0.0005 0.0013 0.0008 0.001 0.0004 0.0009 0.0004
Vacuole Periphery 0.0003 0.0002 0.0002 0.0003 0.0001 0.0006 0.0004 0.0001 0.0002 0.0004 0.0003 0.0002 0.0002 0.0001 0.0003 0.0001 0.0002 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 27.0013 16.9615 17.9111 19.1444 20.8158 26.257 19.6233 24.708 25.6786 30.922
Translational Efficiency 0.845 0.6922 0.713 0.8343 0.786 0.9837 1.0283 0.7695 0.965 0.9817

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1455 1543 282 1741 996 895 1453 368 2451 2438 1735 2109

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 776.61 825.40 1245.87 874.66 939.47 756.82 1134.31 932.95 842.79 800.22 1152.44 884.83
Standard Deviation 113.77 181.53 276.61 153.01 152.91 173.58 228.14 147.45 153.57 181.69 240.25 153.66
Intensity Change Log 2 — 0.087903 0.681891 0.171532 — -0.311897 0.271896 -0.010047 — -0.117167 0.471954 0.074967

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000070 0.000248 0.000793 0.000914 0.000176 0.000273 0.000205 0.003754 0.000113 0.000257 0.000301 0.001410
Bud Neck 0.002734 0.011264 0.003679 0.018138 0.001043 0.011744 0.001733 0.010850 0.002047 0.011440 0.002049 0.016866
Bud Site 0.004361 0.014141 0.006027 0.046441 0.003192 0.013710 0.002416 0.023303 0.003886 0.013982 0.003003 0.042403
Cell Periphery 0.000129 0.000119 0.000312 0.000174 0.000097 0.000135 0.000086 0.000211 0.000116 0.000125 0.000123 0.000181
Cytoplasm 0.727263* 0.720888* 0.459415* 0.529813* 0.771102* 0.648662* 0.656006* 0.511832* 0.745078* 0.694373* 0.624053* 0.526675*
Cytoplasmic Foci 0.064667 0.088520 0.020963 0.015511 0.079602 0.118200 0.005592 0.015448 0.070736 0.099416 0.008090 0.015500
Eisosomes 0.000033 0.000043 0.000063 0.000027 0.000025 0.000070 0.000014 0.000106 0.000030 0.000053 0.000022 0.000041
Endoplasmic Reticulum 0.000469 0.000692 0.005094 0.001372 0.001259 0.000790 0.001318 0.002322 0.000790 0.000728 0.001931 0.001537
Endosome 0.001819 0.007096 0.005367 0.006460 0.004048 0.016915 0.001139 0.004356 0.002725 0.010700 0.001826 0.006093
Golgi 0.000465 0.001444 0.000303 0.005681 0.000912 0.004485 0.000128 0.003224 0.000647 0.002560 0.000157 0.005252
Lipid Particles 0.000978 0.001621 0.003418 0.000968 0.001020 0.005025 0.000660 0.001070 0.000995 0.002871 0.001108 0.000986
Mitochondria 0.000426 0.002581 0.000417 0.002425 0.000324 0.005395 0.000657 0.000873 0.000384 0.003614 0.000618 0.002155
Mitotic Spindle 0.001486 0.002643 0.003244 0.058288 0.002435 0.005683 0.010132 0.033258 0.001872 0.003759 0.009013 0.053921
None 0.012951 0.013381 0.007777 0.009311 0.004785 0.011854 0.009703 0.008159 0.009632 0.012820 0.009390 0.009110
Nuclear Periphery 0.000175 0.000170 0.001710 0.001507 0.000218 0.000302 0.000868 0.001364 0.000192 0.000219 0.001005 0.001482
Nuclear Periphery Foci 0.000591 0.001990 0.007059 0.001502 0.005105 0.002480 0.001623 0.001465 0.002425 0.002170 0.002506 0.001495
Nucleolus 0.000362 0.001132 0.000750 0.001443 0.000249 0.003906 0.000179 0.000499 0.000316 0.002150 0.000272 0.001278
Nucleus 0.161357* 0.076120 0.347454* 0.218963* 0.081910 0.065705 0.260137* 0.222646* 0.129072 0.072296 0.274329* 0.219606*
Peroxisomes 0.000410 0.003119 0.000409 0.002189 0.000419 0.006253 0.000109 0.004189 0.000414 0.004269 0.000158 0.002538
Vacuole 0.019010 0.051855 0.125437 0.075873 0.041376 0.076907 0.047155 0.145180 0.028098 0.061052 0.059879 0.087966
Vacuole Periphery 0.000245 0.000935 0.000307 0.003000 0.000703 0.001507 0.000140 0.005893 0.000431 0.001145 0.000167 0.003505

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.18 -10.69 -6.85 -3.79 4.28 -1.47 -1.63 -1.33 -1.20 -1.20 -5.03 -8.41 -4.00 -2.83 -1.84
Bud Neck -6.10 -3.51 -8.36 -1.72 -6.89 -6.02 -5.31 -4.71 1.35 -3.83 -8.60 -1.83 -10.13 -1.30 -9.93
Bud Site -6.22 -3.07 -9.10 -4.36 -6.70 -7.21 0.18 -4.30 -0.48 -4.36 -9.01 -0.33 -10.28 -4.54 -10.45
Cell Periphery 1.63 -8.52 0.51 -0.77 8.46 -2.97 1.11 -0.82 0.72 -1.20 -0.67 -2.27 -0.62 -0.13 1.06
Cytoplasm 1.47 23.13 37.05 32.91 -1.99 10.07 21.03 25.63 16.44 13.33 7.72 27.26 46.47 35.22 15.74
Cytoplasmic Foci -5.39 14.63 18.17 19.74 2.06 -5.68 19.52 16.97 19.19 -4.74 -7.56 28.69 24.08 26.93 -5.66
Eisosomes -2.42 -5.53 -3.15 0.62 4.43 -8.28 3.31 -3.77 -0.36 -4.35 -7.24 2.24 -5.69 1.66 -7.11
Endoplasmic Reticulum -3.12 -9.75 -15.84 -12.76 6.52 2.52 -1.80 -5.22 -6.88 -4.42 0.81 -9.55 -12.37 -13.82 -0.05
Endosome -8.92 -7.04 -3.32 5.23 3.32 -8.01 8.05 0.87 8.13 -4.61 -11.30 4.14 -1.48 9.44 -3.81
Golgi -2.82 0.38 -1.81 -0.32 -2.23 -2.95 2.32 0.24 2.89 -1.16 -3.86 2.26 -1.55 1.61 -2.76
Lipid Particles -3.63 -7.49 -4.27 0.16 5.83 -4.75 1.57 -4.18 3.74 -5.23 -5.68 -2.71 -5.60 3.72 -2.48
Mitochondria -3.06 -0.38 -5.91 1.50 -7.12 -3.79 -1.53 -3.34 3.43 -1.42 -4.86 -1.27 -6.98 3.30 -5.31
Mitotic Spindle -1.49 -2.50 -14.01 -13.77 -12.63 -1.55 -4.37 -6.24 -5.92 -5.37 -2.08 -5.52 -15.27 -14.79 -12.74
None 0.11 4.46 2.20 2.40 -4.23 -3.54 -6.90 -4.80 0.30 -1.56 -1.91 1.57 -0.21 2.18 -3.20
Nuclear Periphery -0.26 -18.87 -22.05 -22.08 -3.00 -1.24 -20.92 -13.72 -13.00 -7.71 -1.14 -29.75 -25.11 -24.61 -11.67
Nuclear Periphery Foci -6.88 -8.95 -5.42 -1.99 5.29 4.34 5.44 1.56 -1.73 -2.27 0.87 -2.28 -1.62 -2.24 -0.08
Nucleolus -5.46 -1.98 -5.07 -2.55 -4.48 -3.81 0.45 -2.71 1.50 -2.73 -5.03 1.20 -5.83 0.19 -5.94
Nucleus 16.17 -12.18 -15.56 -31.07 4.33 2.98 -31.20 -13.35 -14.35 2.93 14.68 -27.35 -23.45 -34.82 3.91
Peroxisomes -5.21 0.59 -3.46 3.42 -3.99 -6.17 3.92 -1.25 4.01 -1.71 -8.05 4.05 -3.59 5.76 -4.98
Vacuole -12.76 -14.86 -27.46 -18.56 2.86 -7.56 -10.92 -14.62 -11.56 -10.48 -13.72 -19.57 -29.38 -20.71 -9.91
Vacuole Periphery -6.06 -1.19 -1.99 0.16 -1.80 -2.11 2.14 -0.45 0.26 -1.04 -4.42 2.45 -1.48 0.58 -2.49
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ferulic acid decarboxylase; involved in the decarboxylation of aromatic carboxylic acids such as phenylacrylic (cinnamic) acid, ferulic acid and coumaric acid and formation of the corresponding vinyl derivatives; overexpression of both Pad1p and Fdc1p increases decarboxylase activity due to the Pad1p-catalyzed formation of a diffusible cofactor required for Fdc1p activity; homolog of E. coli UbiD; GFP-fusion protein localizes to the cytoplasm in an HTP study
Localization
Cell Percentages cytoplasm (97%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Fdc1

Fdc1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Fdc1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available