Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L12A; rpl12a rpl12b double mutant exhibits slow growth and slow translation; homologous to mammalian ribosomal protein L12 and bacterial L11; RPL12A has a paralog, RPL12B, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0.07 0.06 0 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0.99 0.98 0.97 0.99 0.96 0.9 – 0.71 0.77 0.63 0.67 0.65 0.94 0.98 0.95 – – – 0.98 0.93 0.9 0.9 0.87 0.83
Endoplasmic Reticulum 0 0 0 0 0 0.09 – 0.19 0.14 0.26 0.14 0.22 0 0 0 – – – 0 0 0.06 0.05 0.06 0.07
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0.06 0 0 0.05 0 0 0 0 – – – 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 – 0.07 0.12 0.09 0.25 0.18 0 0 0 – – – 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 3 – 8 5 7 7 6 0 0 0 – – – 0 0 0 0 0 1
Bud 0 0 0 0 0 0 – 1 0 0 0 0 0 1 2 – – – 1 0 0 1 2 4
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 2 2 2 2 3 4 – 8 6 13 11 9 5 4 10 – – – 0 0 1 0 0 0
Cytoplasm 257 316 222 208 174 209 – 175 153 118 128 145 198 191 293 – – – 237 288 208 165 154 156
Endoplasmic Reticulum 2 10 7 3 6 20 – 46 27 48 26 50 8 6 9 – – – 0 8 12 8 9 12
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Golgi 1 0 0 0 1 1 – 15 4 8 9 4 0 0 0 – – – 0 0 0 0 0 2
Mitochondria 0 0 3 0 0 4 – 18 23 16 48 40 0 0 0 – – – 0 1 2 0 2 2
Nucleus 0 0 1 0 0 0 – 0 0 0 0 0 0 0 1 – – – 1 1 0 1 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 1 0 1 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 1 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 – 3 0 0 2 1 0 0 1 – – – 0 4 2 2 2 2
Unique Cell Count 259 323 230 211 182 233 246 199 187 190 223 210 194 310 241 310 232 185 177 188
Labelled Cell Count 262 328 236 213 184 242 274 218 211 231 256 211 202 316 241 310 232 185 177 188


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 50.2 57.8 31.2 50.3 51.1 41.8 – 34.0 30.5 30.6 27.0 26.2 54.2 54.5 53.6 – – – 53.1 58.5 57.0
Std Deviation (1e-4) 12.3 10.8 8.4 10.4 12.2 9.4 – 8.6 6.7 7.9 6.7 6.8 13.7 11.4 10.3 – – – 11.9 18.4 18.3
Intensity Change (Log2) – – – 0.69 0.71 0.42 – 0.12 -0.03 -0.03 -0.21 -0.26 0.8 0.8 0.78 – – – 0.76 0.91 0.87

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP7000204060WT3HU80HU120HU1600204060WT30204060WT1AF100AF140AF1800204060
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 – 0 0 0 0 0 0 0 0 – – –
Bud 0 0 0 – 0 0 0 0 0 0 0 0 – – –
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 – – –
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 – – –
Cell Periphery 0 0 0 – 0 0 3.3 2.9 2.2 0 0 1.8 – – –
Cytoplasm 1.4 -0.5 -2.9 – -7.4 -6.1 -8.7 -8.0 -8.5 -1.1 1.2 -1.1 – – –
Endoplasmic Reticulum 0 0.1 2.5 – 5.4 4.0 6.8 4.0 6.2 0.4 0 -0.1 – – –
Endosome 0 0 0 – 0 0 0 0 0 0 0 0 – – –
Golgi 0 0 0 – 3.8 0 0 0 0 0 0 0 – – –
Mitochondria 0 0 0 – 3.2 4.4 3.5 7.5 6.0 0 0 0 – – –
Nucleus 0 0 0 – 0 0 0 0 0 0 0 0 – – –
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 – – –
Nucleolus 0 0 0 – 0 0 0 0 0 0 0 0 – – –
Peroxisomes 0 0 0 – 0 0 0 0 0 0 0 0 – – –
SpindlePole 0 0 0 – 0 0 0 0 0 0 0 0 – – –
Vacuole 0 0 0 – 0 0 0 0 0 0 0 0 – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 82.1796 121.3527 110.5823 94.0008 98.7552 93.2452 66.8249 103.9227 101.0622 89.6284 77.6343 97.9287 98.1046 123.3063 115.4588 114.3482 107.2465 114.4426
Actin 0.0023 0.0004 0.008 0.0007 0.0003 0.0025 0.0383 0.0008 0.0026 0.0117 0.0059 0.0022 0.0012 0.0002 0.0008 0.0001 0.0006 0.001
Bud 0.0033 0.0005 0.0028 0.0017 0.0011 0.0035 0.0048 0.0009 0.0015 0.0032 0.006 0.0005 0.0009 0.0003 0.0012 0.0006 0.0002 0.0007
Bud Neck 0.0006 0.0005 0.0008 0.0005 0.0008 0.0012 0.0048 0.0006 0.0005 0.0127 0.0008 0.0013 0.0006 0.0005 0.0007 0.0003 0.0004 0.0014
Bud Periphery 0.0038 0.0003 0.0025 0.0007 0.0006 0.004 0.0094 0.0004 0.001 0.006 0.0125 0.0001 0.0011 0.0002 0.0017 0.0001 0.0001 0.0004
Bud Site 0.0013 0.0007 0.0022 0.0005 0.0002 0.0006 0.0053 0.0006 0.0015 0.0047 0.0017 0.0001 0.0005 0.0002 0.0004 0.0001 0.0001 0.0001
Cell Periphery 0.01 0.0128 0.0164 0.0191 0.0016 0.0006 0.0085 0.0066 0.008 0.0086 0.0021 0.0014 0.0128 0.0118 0.0102 0.0049 0.0012 0.0087
Cytoplasm 0.702 0.9067 0.801 0.636 0.8126 0.7027 0.6432 0.9357 0.8655 0.7249 0.5535 0.9605 0.8136 0.928 0.8656 0.8099 0.8816 0.8438
Cytoplasmic Foci 0.0159 0.0023 0.0099 0.0407 0.0258 0.0337 0.0159 0.0015 0.005 0.0024 0.0055 0.0072 0.0017 0.0012 0.0025 0.0018 0.0067 0.0062
Eisosomes 0.0002 0.0005 0.001 0.0003 0.0002 0.0001 0.001 0 0.0001 0.0016 0.0003 0 0.0015 0 0 0 0 0.0065
Endoplasmic Reticulum 0.0541 0.019 0.0132 0.004 0.011 0.0079 0.0634 0.0076 0.0073 0.0031 0.0165 0.0036 0.0349 0.0096 0.0262 0.0016 0.0022 0.0465
Endosome 0.0192 0.002 0.0052 0.0114 0.0191 0.1005 0.0208 0.0023 0.0067 0.0601 0.0403 0.0097 0.0084 0.0024 0.0075 0.0053 0.01 0.0291
Golgi 0.003 0.0007 0.0019 0.0017 0.001 0.0217 0.0089 0.0006 0.0016 0.005 0.0045 0.002 0.0012 0.0004 0.0018 0.0001 0.0008 0.0073
Lipid Particles 0.0065 0.0012 0.0031 0.0464 0.0171 0.0035 0.0068 0.0006 0.0018 0.0011 0.0006 0.001 0.0013 0.0033 0.0014 0.0003 0.0059 0.0038
Mitochondria 0.014 0.0011 0.0106 0.023 0.0027 0.0205 0.0142 0.0004 0.0271 0.0067 0.1068 0.0005 0.0095 0.0001 0.0017 0.0001 0.0005 0.0031
None 0.0113 0.0005 0.0075 0.0051 0.0039 0.0054 0.0106 0.0002 0.0009 0.0004 0.0026 0.0005 0.0015 0.0001 0.0003 0.0001 0.0002 0.0007
Nuclear Periphery 0.021 0.0028 0.0072 0.0092 0.0067 0.0068 0.0236 0.0022 0.0031 0.0052 0.0161 0.0015 0.0146 0.0021 0.0053 0.004 0.0035 0.0091
Nucleolus 0.0108 0.0016 0.0033 0.007 0.0014 0.0038 0.007 0.0001 0.0011 0.0018 0.0003 0.0002 0.0018 0.0002 0.0002 0.0002 0.0001 0.0005
Nucleus 0.0113 0.002 0.0043 0.0058 0.0023 0.0058 0.0105 0.0014 0.002 0.0041 0.0034 0.0012 0.0071 0.0011 0.0018 0.0023 0.0012 0.0017
Peroxisomes 0.0018 0.0001 0.0005 0.0041 0.0006 0.001 0.0018 0 0.0008 0.0002 0.0005 0.0001 0.0001 0 0 0 0.0283 0.0001
Punctate Nuclear 0.0017 0 0.0006 0.0014 0.0003 0.0158 0.0027 0 0.0004 0.0001 0.0001 0.0001 0.0003 0 0 0 0.0002 0.0001
Vacuole 0.0842 0.04 0.0837 0.1316 0.0664 0.035 0.08 0.0345 0.0509 0.1118 0.1356 0.0046 0.0727 0.0349 0.0606 0.1377 0.0482 0.0187
Vacuole Periphery 0.0218 0.0041 0.0142 0.0492 0.0242 0.0233 0.0185 0.0031 0.0105 0.0245 0.0845 0.0017 0.0129 0.003 0.0099 0.0304 0.0081 0.0104

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 1966.4085 2131.2063 2320.7295 2022.0366 2138.7364 1620.9737 1826.4245 1680.1128 1695.8021 1641.8428
Translational Efficiency 1.4444 1.4552 1.2884 1.3436 1.4834 1.6299 1.3207 1.3959 1.2756 1.4412

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2014 58 1344 1557 1589 1782 1804 610 3603 1840 3148 2167

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 2222.70 3810.99 4349.49 3922.91 3185.69 3480.98 4741.71 3921.29 2647.40 3491.38 4574.26 3922.45
Standard Deviation 460.76 795.59 746.67 1221.11 612.23 750.42 875.97 989.79 715.96 754.09 845.81 1160.67
Intensity Change Log 2 — 0.777853 0.968533 0.819611 — 0.127888 0.573802 0.299722 — 0.431109 0.749272 0.536427

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000064 0.000311 0.000147 0.000528 0.000043 0.000063 0.000116 0.000427 0.000055 0.000071 0.000129 0.000500
Bud Neck 0.000147 0.001752 0.002000 0.002412 0.000117 0.000355 0.001034 0.001991 0.000133 0.000399 0.001446 0.002293
Bud Site 0.006398 0.005877 0.006213 0.017722 0.001889 0.004186 0.004701 0.017566 0.004409 0.004240 0.005346 0.017678
Cell Periphery 0.006291 0.064582 0.017633 0.022273 0.005892 0.007201 0.021246 0.047346 0.006115 0.009010 0.019704 0.029331
Cytoplasm 0.699666 0.325637 0.574868 0.567885 0.753219 0.765350 0.559298 0.515685 0.723284 0.751490 0.565946 0.553191
Cytoplasmic Foci 0.040475 0.017636 0.012593 0.010227 0.013648 0.015326 0.007085 0.010005 0.028644 0.015399 0.009437 0.010165
Eisosomes 0.000001 0.000012 0.000003 0.000006 0.000001 0.000001 0.000002 0.000006 0.000001 0.000001 0.000003 0.000006
Endoplasmic Reticulum 0.005081 0.002575 0.001003 0.000971 0.002201 0.001188 0.001413 0.000591 0.003811 0.001232 0.001238 0.000864
Endosome 0.002655 0.003549 0.001425 0.003326 0.000984 0.001324 0.001131 0.003495 0.001918 0.001394 0.001257 0.003373
Golgi 0.080324 0.173254 0.069781 0.032878 0.062293 0.078927 0.051933 0.038081 0.072372 0.081900 0.059553 0.034342
Lipid Particles 0.007681 0.059399 0.017968 0.018207 0.007048 0.008549 0.024268 0.037335 0.007402 0.010152 0.021579 0.023592
Mitochondria 0.000477 0.000167 0.000177 0.001344 0.000208 0.000193 0.000149 0.000508 0.000359 0.000192 0.000161 0.001109
Mitotic Spindle 0.000860 0.002452 0.002637 0.004522 0.000644 0.001551 0.001109 0.001446 0.000765 0.001580 0.001761 0.003656
None 0.001199 0.000887 0.001211 0.001048 0.000927 0.001299 0.000669 0.000644 0.001079 0.001286 0.000901 0.000934
Nuclear Periphery 0.000139 0.001235 0.001281 0.000464 0.000252 0.000249 0.000738 0.000478 0.000189 0.000280 0.000970 0.000468
Nuclear Periphery Foci 0.006735 0.035636 0.018808 0.006109 0.009328 0.010196 0.012441 0.008399 0.007878 0.010998 0.015159 0.006754
Nucleolus 0.000214 0.000163 0.000098 0.000314 0.000037 0.000042 0.000081 0.000479 0.000136 0.000045 0.000089 0.000360
Nucleus 0.001136 0.003776 0.009074 0.006921 0.001644 0.002000 0.004240 0.004555 0.001360 0.002056 0.006304 0.006255
Peroxisomes 0.000094 0.000130 0.000025 0.000192 0.000027 0.000033 0.000036 0.000426 0.000064 0.000036 0.000032 0.000258
Vacuole 0.039737 0.192710 0.169104 0.240289 0.047730 0.041597 0.229469 0.263880 0.043262 0.046361 0.203697 0.246930
Vacuole Periphery 0.100625 0.108262 0.093949 0.062363 0.091868 0.060367 0.078838 0.046656 0.096763 0.061876 0.085290 0.057942

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.89 -6.90 -3.02 -1.12 -2.24 -2.19 -6.39 -4.28 -4.09 -3.43 -2.07 -9.25 -4.04 -3.89 -3.18
Bud Neck -3.88 -10.66 -8.20 -2.14 -0.81 -4.50 -10.57 -9.65 -8.23 -4.20 -5.00 -14.63 -10.50 -9.03 -3.31
Bud Site 0.22 -0.85 -7.76 -5.81 -7.29 -4.20 -7.19 -7.87 -6.70 -6.28 0.22 -3.27 -11.30 -11.04 -10.03
Cell Periphery -5.65 -11.21 -9.27 4.24 -1.77 -1.86 -13.36 -11.28 -10.78 -6.69 -3.76 -17.14 -14.36 -11.32 -4.95
Cytoplasm 8.28 11.42 12.31 -5.20 0.02 -1.10 18.05 14.67 15.57 2.06 -3.09 20.56 19.18 19.36 0.61
Cytoplasmic Foci 4.95 13.73 16.21 1.61 2.71 -1.64 6.52 2.41 3.73 -2.18 10.11 16.13 14.97 4.83 -0.41
Eisosomes -1.82 -7.04 -6.16 1.05 -3.72 -1.93 -9.52 -4.77 -4.52 -3.29 -1.24 -11.21 -7.96 -7.06 -5.15
Endoplasmic Reticulum 2.74 10.37 10.44 1.96 0.65 3.73 2.04 6.58 3.62 2.21 9.18 8.28 11.91 2.55 1.82
Endosome -1.17 7.64 -1.41 0.37 -4.32 -3.65 -2.03 -2.47 -2.11 -2.29 4.76 6.67 -3.41 -4.70 -4.99
Golgi -5.30 3.16 15.12 8.24 13.21 -4.05 3.58 7.53 11.38 5.49 -2.62 5.68 16.86 15.07 13.95
Lipid Particles -3.73 -9.32 -8.02 3.01 0.77 -1.64 -12.72 -10.74 -10.16 -4.30 -3.05 -15.80 -13.11 -9.28 -0.82
Mitochondria 2.43 4.34 -2.18 -2.92 -2.97 0.39 2.21 -0.99 -1.04 -1.18 3.49 4.93 -2.53 -3.13 -3.22
Mitotic Spindle -1.61 -7.25 -4.27 -1.77 -1.77 -4.23 -3.75 -2.19 0.30 -0.47 -3.93 -7.88 -4.60 -3.22 -2.64
None 0.97 -0.09 0.46 -0.54 0.81 -1.69 4.93 2.38 2.69 0.27 -0.83 1.15 0.68 1.36 -0.14
Nuclear Periphery -5.41 -12.99 -4.85 3.56 7.80 -0.05 -12.92 -2.24 -2.24 3.08 -4.56 -18.05 -4.99 -3.18 7.89
Nuclear Periphery Foci -5.10 -12.04 1.29 5.22 12.94 -1.07 -4.39 1.10 2.04 4.97 -4.46 -12.66 2.56 6.24 15.06
Nucleolus 0.26 0.63 -0.77 -1.64 -5.11 -1.51 -16.12 -1.51 -1.49 -1.37 0.93 0.42 -1.95 -3.48 -3.02
Nucleus -2.56 -11.66 -9.53 -4.20 1.43 -0.92 -6.15 -5.74 -6.46 -0.13 -2.42 -13.13 -10.60 -9.76 -0.70
Peroxisomes -0.44 6.02 -2.80 -0.59 -5.28 -1.17 -1.94 -1.82 -1.80 -1.79 3.52 4.85 -2.78 -3.19 -3.25
Vacuole -6.80 -23.15 -30.82 -2.44 -8.12 1.88 -30.96 -20.68 -21.33 -2.43 -1.36 -38.97 -36.81 -34.62 -5.98
Vacuole Periphery -0.45 1.98 10.51 3.24 7.91 7.24 3.52 10.09 4.05 8.28 10.04 4.39 13.82 2.50 10.35
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L12A; rpl12a rpl12b double mutant exhibits slow growth and slow translation; homologous to mammalian ribosomal protein L12 and bacterial L11; RPL12A has a paralog, RPL12B, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-2

Rpl12a

Rpl12a


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpl12a-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available