Standard name
Human Ortholog
Description GTPase that associates with nuclear 60S pre-ribosomes; required for export of 60S ribosomal subunits from the nucleus
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.05 0.05 0.05 0 0 0 0 0 0 0.06 0.09 0.11 0.08 0.09 0.07 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.08 0 0.11 0.31 0.11 0.33 0.22 0.19 0.24 0.24 0.27 0.21 0.26 0.24 0.17 0.06 0.08 0.1 0 0 0 0 0.07 0.05
Nucleus 0.79 0.83 0.4 0.16 0.16 0.28 0.4 0.46 0.31 0.45 0.32 0.52 0.12 0.05 0 0.43 0.42 0.51 0.51 0.67 0.26 0.22 0.15 0.15
Nuclear Periphery 0 0 0 0 0 0.07 0.06 0.06 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.32 0.17 0.6 0.84 0.74 0.62 0.58 0.47 0.61 0.52 0.62 0.45 0.84 0.86 0.83 0.45 0.46 0.44 0.39 0.26 0.64 0.57 0.49 0.39
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.07 0 0.05 0.05 0.06 0.13 0.22 0.3
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 2 2 1 1 0 0 0 0 1 1 0 1 3 2
Bud Neck 0 0 0 0 0 0 0 0 1 0 1 0 0 1 1 0 0 0 0 0 0 0 0 2
Bud Site 0 0 0 0 0 0 3 5 3 1 2 9 0 1 1 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0
Cytoplasm 3 2 4 4 6 4 6 5 3 7 1 2 18 35 47 38 39 17 1 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 5 2 0 0 0 0 0 0
Endosome 0 2 0 0 3 1 2 1 1 0 2 0 3 1 6 3 1 0 2 0 0 2 2 9
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 2
Mitochondria 20 6 15 23 13 25 42 28 22 38 40 50 78 96 69 32 34 26 0 0 1 6 18 14
Nucleus 204 251 57 12 20 21 75 70 29 72 46 124 37 20 17 214 171 131 146 226 40 48 41 39
Nuclear Periphery 1 1 1 0 2 5 11 9 3 5 9 9 0 1 0 3 0 0 3 3 2 1 4 6
Nucleolus 82 53 84 63 91 47 110 71 57 83 91 106 254 336 345 221 191 114 111 88 97 125 134 104
Peroxisomes 0 0 0 0 1 0 0 0 0 0 0 0 1 8 11 1 0 1 0 0 0 0 0 0
SpindlePole 0 0 1 2 2 0 3 2 2 1 1 1 1 9 20 1 1 0 1 0 0 2 4 4
Vac/Vac Membrane 2 8 4 0 4 0 1 2 1 0 1 2 1 4 4 33 29 11 15 18 8 28 61 81
Unique Cell Count 257 304 141 75 123 76 189 151 93 160 146 237 304 392 418 494 412 257 287 340 153 220 277 271
Labelled Cell Count 312 323 166 104 142 103 253 194 122 207 196 305 394 513 522 554 472 303 287 340 153 220 277 271


Nucleolus, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 26.2 29.7 22.5 18.1 16.0 12.0 9.9 9.7 9.5 8.1 8.6 8.7 26.6 23.3 22.4 29.6 36.9 31.7 22.1 19.8 20.7
Std Deviation (1e-4) 8.3 8.2 6.6 6.3 5.9 5.0 3.2 3.1 2.7 2.4 2.5 2.5 10.7 9.7 10.2 13.7 16.8 14.3 6.5 5.7 6.1
Intensity Change (Log2) – – – -0.31 -0.49 -0.9 -1.18 -1.22 -1.24 -1.47 -1.39 -1.38 0.24 0.05 -0.0 0.4 0.72 0.5 -0.02 -0.18 -0.12

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002040WT3HU80HU120HU16002040WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302040WT1AF100AF140AF18002040
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0.7 0 0 1.4 2.4 3.0 2.0 2.5 1.6
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 3.7 0 4.0 2.8 1.9 2.7 3.0 3.6 2.6 3.6 3.5 1.7 -1.7 -0.9 -0.2
Nucleus -3.7 -4.3 -1.9 -0.1 1.0 -1.4 0.8 -1.6 2.2 -6.8 -10.2 -11.0 0.6 0.2 2.0
Nuclear Periphery 0 0 0 2.5 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 3.7 2.5 0.3 -0.3 -2.1 0.3 -1.3 0.5 -2.8 5.5 6.5 5.6 -3.1 -2.7 -2.9
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 2.2 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 1.7 1.8 0.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 23.4496 28.2283 26.7992 25.8131 24.0027 27.6566 22.5189 27.3524 25.1957 24.2928 22.2788 24.6331 22.2696 25.376 28.0285 20.8166 22.3745 24.6529
Actin 0.0138 0.0001 0.0005 0.0002 0.042 0.0002 0.006 0.0004 0.0063 0 0.0323 0.0001 0 0.0163 0 0.0421 0 0.0001
Bud 0.0011 0.0009 0.0002 0.0003 0.0004 0.0001 0.0002 0.0001 0.0001 0 0.0007 0.0001 0.0001 0.0001 0 0.0004 0.0001 0.0001
Bud Neck 0.002 0.0002 0.0001 0.0001 0.0005 0.0002 0.0004 0.0002 0.0029 0.0001 0.0006 0.0002 0.0001 0.0001 0.0001 0.001 0.0001 0.0001
Bud Periphery 0.0017 0.0008 0.0002 0.0004 0.0008 0.0004 0.0003 0.0001 0.0002 0.0002 0.0014 0.0004 0.0003 0.0002 0.0001 0.0005 0.0001 0.0004
Bud Site 0.0074 0.0013 0.0003 0.0006 0.0009 0.0001 0.0006 0.0005 0.0013 0.0001 0.0018 0.0001 0.0002 0.0003 0.0001 0.0019 0.0001 0.0001
Cell Periphery 0.0028 0.0011 0.0005 0.0007 0.0004 0.0008 0.0005 0.0001 0.0004 0.0004 0.0007 0.0009 0.0003 0.0003 0.0002 0.0003 0.0002 0.0005
Cytoplasm 0.0012 0.0001 0.0176 0.0009 0.0001 0.0012 0.0042 0.0004 0.0006 0.0001 0.0005 0 0 0 0 0.0106 0 0
Cytoplasmic Foci 0.0233 0.0023 0.002 0.0014 0.0027 0.0034 0.0167 0.0046 0.0005 0.0002 0.0193 0.0001 0.0067 0.0039 0 0.0082 0 0
Eisosomes 0.0004 0 0 0.0001 0.0002 0 0.0002 0 0 0 0.0003 0 0.0001 0.0001 0 0.0005 0 0
Endoplasmic Reticulum 0.0005 0 0.0007 0.0001 0.0002 0.0003 0.0022 0 0.0017 0 0.0009 0 0 0 0 0.0071 0 0
Endosome 0.0021 0.0002 0.009 0.0002 0.0045 0.0009 0.0088 0.0003 0.0046 0.0001 0.0043 0.0001 0.0001 0.0008 0 0.0231 0 0
Golgi 0.0011 0 0.0031 0.0001 0.0196 0.0001 0.0012 0.0005 0.0022 0 0.0034 0 0 0.0043 0 0.0048 0 0
Lipid Particles 0.0115 0.0007 0.0006 0.0016 0.0052 0.0015 0.0094 0.0002 0.0006 0.0007 0.0073 0.0009 0.0009 0.0304 0.0002 0.007 0 0.0005
Mitochondria 0.0112 0.0079 0.0072 0.011 0.0072 0.0031 0.0065 0.0008 0.0024 0.0013 0.0134 0.0035 0.0044 0.0154 0.001 0.0026 0.0015 0.0189
None 0.0039 0.0002 0.0003 0.0008 0.0001 0.0057 0.0044 0 0.0002 0.0001 0.0028 0.0001 0.0005 0.0001 0 0.0151 0 0
Nuclear Periphery 0.0049 0.0144 0.0011 0.0047 0.0328 0.0099 0.009 0.0032 0.0036 0.0168 0.0359 0.0134 0.0013 0.0017 0.0018 0.0478 0.0005 0.0053
Nucleolus 0.5709 0.4151 0.6703 0.5792 0.4701 0.5724 0.5796 0.6273 0.7121 0.6094 0.4715 0.668 0.779 0.7015 0.8157 0.3962 0.4459 0.7193
Nucleus 0.2907 0.5399 0.2832 0.3853 0.3983 0.3766 0.3293 0.3558 0.2521 0.3523 0.3827 0.2942 0.2001 0.2149 0.1758 0.4115 0.5504 0.2466
Peroxisomes 0.0011 0.0006 0.0004 0.0004 0.0017 0.0001 0.0011 0.0035 0.0001 0 0.0021 0 0.0002 0.002 0 0.0027 0 0
Punctate Nuclear 0.0037 0.0006 0.0004 0.0012 0.0005 0.0008 0.0146 0.0012 0.0004 0.0005 0.0032 0.0006 0.001 0.0017 0.0002 0.0108 0.0001 0.0006
Vacuole 0.0107 0.0036 0.0012 0.0025 0.0017 0.0046 0.0018 0.0002 0.0024 0.0033 0.0039 0.0028 0.0019 0.0011 0.0009 0.0016 0.0004 0.0015
Vacuole Periphery 0.0338 0.0099 0.0013 0.0085 0.01 0.0177 0.0031 0.0009 0.0054 0.0144 0.0111 0.0145 0.0026 0.0048 0.0037 0.0041 0.0006 0.0059

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 122.1299 126.8468 108.1745 76.9012 90.1569 83.9619 89.0126 68.0448 56.7627 88.1251
Translational Efficiency 1.8817 1.9787 1.5611 1.8485 1.8723 1.818 1.7279 1.6514 1.5312 1.7127

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
208 1171 359 1805 877 1165 1611 2054 1085 2336 1970 3859

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1576.08 1632.90 2343.27 2977.57 1676.54 1766.13 2415.51 3020.50 1657.28 1699.34 2402.35 3000.42
Standard Deviation 329.39 505.61 412.66 823.73 419.91 504.58 534.69 931.21 406.07 509.47 515.37 882.83
Intensity Change Log 2 — 0.051096 0.572182 0.917795 — 0.075105 0.526841 0.849300 — 0.063521 0.548989 0.882896

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000653 0.000928 0.000835 0.001433 0.000760 0.000841 0.001073 0.001269 0.000739 0.000884 0.001030 0.001345
Bud Neck 0.002692 0.002693 0.004272 0.005579 0.002570 0.002912 0.003882 0.010157 0.002594 0.002802 0.003953 0.008016
Bud Site 0.000520 0.000933 0.000312 0.000664 0.000290 0.000425 0.000271 0.001652 0.000334 0.000680 0.000278 0.001190
Cell Periphery 0.000045 0.000060 0.000011 0.000179 0.000047 0.000032 0.000024 0.000225 0.000046 0.000046 0.000021 0.000203
Cytoplasm 0.000688 0.000253 0.000010 0.000370 0.000060 0.000360 0.000033 0.000933 0.000181 0.000306 0.000029 0.000670
Cytoplasmic Foci 0.000498 0.000678 0.000549 0.002018 0.000232 0.000413 0.000286 0.002368 0.000283 0.000546 0.000334 0.002205
Eisosomes 0.000082 0.000131 0.000105 0.000103 0.000182 0.000136 0.000129 0.000107 0.000163 0.000134 0.000125 0.000105
Endoplasmic Reticulum 0.000666 0.000561 0.000164 0.000262 0.000424 0.000458 0.000223 0.000325 0.000471 0.000509 0.000212 0.000295
Endosome 0.000081 0.000154 0.000010 0.000256 0.000043 0.000060 0.000009 0.000826 0.000050 0.000107 0.000009 0.000559
Golgi 0.000104 0.000122 0.000080 0.000568 0.000054 0.000111 0.000058 0.000577 0.000064 0.000117 0.000062 0.000573
Lipid Particles 0.000036 0.000045 0.000014 0.000054 0.000015 0.000052 0.000004 0.000098 0.000019 0.000049 0.000006 0.000077
Mitochondria 0.001598 0.002261 0.002232 0.005625 0.001732 0.001937 0.002720 0.004448 0.001706 0.002099 0.002631 0.004998
Mitotic Spindle 0.000282 0.002047 0.000361 0.001554 0.000134 0.002157 0.000437 0.003709 0.000163 0.002102 0.000423 0.002701
None 0.000579 0.002781 0.000372 0.000970 0.000632 0.000890 0.000411 0.001900 0.000622 0.001838 0.000404 0.001465
Nuclear Periphery 0.002033 0.000720 0.000534 0.007628 0.000663 0.000495 0.001253 0.005255 0.000926 0.000608 0.001122 0.006365
Nuclear Periphery Foci 0.004393 0.000407 0.000165 0.001504 0.000208 0.000367 0.000145 0.001146 0.001011 0.000387 0.000149 0.001314
Nucleolus 0.567991 0.406408 0.476511 0.517651 0.436939 0.446511 0.479919 0.415271 0.462063 0.426408 0.479298 0.463158
Nucleus 0.404925 0.564666 0.495669 0.425508 0.541708 0.526789 0.494800 0.528342 0.515486 0.545776 0.494958 0.480243
Peroxisomes 0.010277 0.009479 0.016429 0.008952 0.007401 0.011457 0.010961 0.007048 0.007953 0.010466 0.011958 0.007939
Vacuole 0.000490 0.001174 0.000333 0.001901 0.001589 0.000856 0.000513 0.002580 0.001379 0.001015 0.000481 0.002263
Vacuole Periphery 0.001367 0.003501 0.001032 0.017220 0.004315 0.002741 0.002846 0.011765 0.003749 0.003122 0.002516 0.014317

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.48 -2.44 -8.93 -6.68 -8.09 -1.29 -6.63 -8.99 -5.33 -3.33 -3.11 -7.08 -12.88 -8.43 -6.58
Bud Neck 0.02 -2.75 -5.38 -8.32 -3.69 -0.71 -3.37 -10.45 -10.45 -9.51 -0.53 -4.08 -11.73 -12.93 -10.45
Bud Site -0.64 0.94 -0.97 0.28 -4.24 -0.95 0.06 -5.11 -4.52 -5.37 -1.14 0.48 -5.47 -2.09 -6.42
Cell Periphery -0.45 1.36 -2.37 -2.34 -3.25 1.07 1.84 -5.18 -5.78 -6.06 0.03 2.25 -5.07 -5.26 -6.11
Cytoplasm 0.68 1.03 0.46 -1.44 -5.48 -1.04 1.33 -5.72 -1.68 -5.89 -0.66 1.18 -3.40 -2.10 -7.32
Cytoplasmic Foci -0.69 -0.12 -2.86 -2.53 -2.58 -1.75 -0.77 -4.66 -4.32 -4.58 -2.11 -0.57 -5.63 -4.81 -5.49
Eisosomes -2.37 -2.33 -1.97 1.47 0.60 2.43 2.95 4.07 2.78 2.53 1.68 2.56 3.96 2.61 3.25
Endoplasmic Reticulum 0.49 2.54 1.99 3.07 -2.00 -0.43 4.18 1.72 1.20 -2.25 -0.57 4.74 2.97 2.84 -2.27
Endosome -0.56 2.24 -1.45 -0.68 -2.21 -0.68 2.40 -3.01 -2.91 -3.14 -0.98 3.21 -3.43 -2.86 -3.73
Golgi -0.14 0.76 -1.32 -1.30 -1.42 -1.85 -0.74 -2.70 -2.34 -2.68 -2.32 0.24 -2.67 -2.37 -2.68
Lipid Particles -0.16 1.24 -0.54 -0.45 -2.11 -1.67 2.55 -3.15 -1.37 -3.53 -2.02 2.56 -3.45 -1.45 -4.33
Mitochondria -2.00 -2.31 -7.15 -6.03 -6.36 -0.99 -4.09 -6.87 -6.41 -4.29 -2.05 -4.55 -9.80 -8.64 -6.92
Mitotic Spindle -1.54 -0.17 -3.73 0.23 -3.32 -1.83 -1.61 -4.26 -1.47 -3.90 -2.45 -1.58 -5.35 -1.07 -4.75
None -3.02 1.08 -1.71 2.53 -5.20 -1.39 2.59 -3.64 -2.64 -4.35 -3.31 2.77 -4.20 0.86 -5.59
Nuclear Periphery 0.83 0.95 -3.01 -7.23 -7.39 0.76 -1.44 -5.83 -6.13 -4.67 0.89 -0.41 -7.90 -9.45 -7.82
Nuclear Periphery Foci 1.34 1.41 1.02 -5.12 -6.34 -1.21 1.05 -3.68 -2.70 -4.00 1.09 1.48 -0.27 -5.06 -7.30
Nucleolus 7.34 3.63 2.54 -8.94 -2.18 -0.73 -3.25 2.32 3.34 6.50 3.08 -1.42 0.48 -3.51 2.40
Nucleus -7.28 -3.57 -1.14 11.18 3.70 1.12 3.52 0.59 -0.66 -3.44 -2.56 1.69 2.80 6.97 1.12
Peroxisomes 0.54 -3.60 1.01 0.60 5.32 -4.00 -3.99 0.36 4.86 5.04 -3.31 -5.04 -0.11 4.01 5.98
Vacuole -2.43 1.68 -6.14 -2.23 -7.35 1.76 3.00 -2.08 -4.25 -5.70 1.07 3.10 -2.59 -4.69 -8.03
Vacuole Periphery -2.80 0.73 -11.06 -9.14 -11.86 1.76 1.92 -5.37 -7.29 -7.76 0.86 1.97 -9.78 -11.60 -13.20
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description GTPase that associates with nuclear 60S pre-ribosomes; required for export of 60S ribosomal subunits from the nucleus
Localization
Cell Percentages nucleus (68%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-2

Nug1

Nug1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Nug1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available