Standard name
Human Ortholog
Description Pho85p cyclin of the Pho80p subfamily; forms the major Glc8p kinase together with Pcl7p and Pho85p; involved in the control of glycogen storage by Pho85p; stabilized by Elongin C binding; PCL6 has a paralog, PCL7, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.91 0.95 0.95 0.89 0.88 0.86 0.8 0.77 0.72 0.72 0.66 0.75 0.94 0.88 0.86 0.96 0.92 0.9 0.92 0.92 0.92 0.89 0.84 0.84
Endoplasmic Reticulum 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.08 0.14 0.12 0.18 0.16 0.23 0.17 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0.05 0 0 0 0 0 0 0 0.07 0.05
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.08 0 0.07 0.16 0.13 0.09 0.14 0.16 0.15 0.19 0.21 0.13 0 0.16 0.16 0 0.06 0.13 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 5
Bud 0 1 0 4 1 2 9 7 6 6 10 11 0 1 0 0 0 0 0 0 0 0 2 4
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 12
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 0 2 0 0 1 4 2 6 2 4 5 1 2 0 7 6 2 0 0 0 0 0 0
Cytoplasm 208 76 296 230 314 397 500 396 338 414 319 352 351 373 388 235 262 206 247 103 289 196 393 394
Endoplasmic Reticulum 0 4 3 1 1 6 2 1 5 3 1 7 4 3 2 8 9 13 3 0 1 1 1 1
Endosome 3 0 0 3 6 3 2 9 0 4 2 2 0 2 11 1 1 0 2 0 1 0 2 4
Golgi 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 1 2 2 3 0 1 0 0 0
Mitochondria 6 0 1 3 9 37 84 64 83 94 110 80 0 0 0 0 3 4 0 0 2 1 1 4
Nucleus 1 1 3 1 4 13 14 12 20 13 9 11 18 20 23 7 5 2 3 3 3 6 31 21
Nuclear Periphery 1 0 0 0 0 0 0 1 2 0 1 0 0 0 0 0 2 0 0 0 0 0 2 1
Nucleolus 0 0 0 1 1 0 0 0 1 0 1 0 0 0 0 0 1 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 3
Vac/Vac Membrane 19 2 23 41 46 41 84 81 69 109 101 60 16 66 71 7 16 29 2 2 6 6 19 11
Unique Cell Count 228 80 312 259 356 459 622 517 468 579 481 471 372 425 450 246 286 229 269 113 314 222 470 471
Labelled Cell Count 239 84 329 285 383 501 700 573 530 645 558 528 390 467 495 266 307 259 269 113 314 222 470 471


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.5 7.1 7.6 6.9 7.0 6.4 6.4 6.4 6.2 6.1 5.9 5.9 7.8 8.0 7.4 10.6 10.8 10.5 7.4 7.5 7.8
Std Deviation (1e-4) 0.8 1.0 1.0 1.1 1.4 1.2 1.4 1.3 1.4 1.2 1.4 1.2 0.9 1.0 0.9 1.4 1.6 1.7 1.0 1.1 1.2
Intensity Change (Log2) – – – -0.13 -0.11 -0.25 -0.25 -0.25 -0.28 -0.3 -0.37 -0.35 0.04 0.07 -0.03 0.48 0.52 0.48 -0.02 -0.0 0.05

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -2.7 -3.1 -3.8 -5.9 -6.9 -7.9 -8.3 -9.4 -7.3 -0.3 -3.3 -3.9 0.4 -1.6 -2.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 1.9 3.2
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 4.9 6.6 6.3 7.7 7.3 8.9 7.5 0 0 0 0 0 0
Nucleus 0 0 1.8 1.4 1.4 2.7 1.4 0 1.4 2.9 2.9 3.1 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 3.2 2.4 0.8 2.8 3.5 3.1 4.6 5.2 2.4 -1.7 3.4 3.5 -2.4 -0.9 2.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.4844 4.4128 4.3319 3.6821 3.5081 4.1909 1.8825 2.4943 2.3532 1.781 1.3838 1.9674 2.107 2.8834 2.2887 2.3095 2.1439 2.2642
Actin 0.0467 0.0006 0.0067 0.0005 0.0005 0.0006 0.0337 0.0016 0.005 0.0009 0.0007 0.0156 0.0121 0.0011 0.0028 0.0018 0.0172 0.0015
Bud 0.0006 0.0001 0.0003 0.0001 0.0001 0.0001 0.001 0.0002 0.0003 0.0003 0.0001 0.0014 0.0013 0.003 0.0028 0.0014 0.0094 0.0065
Bud Neck 0.0007 0.0002 0.0004 0.0002 0.001 0.0034 0.0086 0.0003 0.0009 0.0012 0.0005 0.0045 0.0018 0.0003 0.0018 0.0017 0.0016 0.0115
Bud Periphery 0.0015 0 0.0001 0 0 0 0.0008 0.0001 0.0002 0.0001 0.0001 0.0024 0.0009 0.0005 0.0009 0.0025 0.004 0.0013
Bud Site 0.0027 0.0009 0.0042 0.0001 0.0001 0.0001 0.0068 0.0015 0.0015 0.0003 0.0001 0.0011 0.0141 0.0108 0.012 0.0063 0.0013 0.0003
Cell Periphery 0.0006 0.0002 0.0001 0.0001 0 0 0.0002 0 0.0001 0 0 0.0001 0.0002 0.0001 0.0002 0.0002 0.0003 0.0001
Cytoplasm 0.5518 0.9156 0.8583 0.8755 0.8964 0.8625 0.7901 0.9391 0.881 0.9029 0.8626 0.9004 0.7083 0.9189 0.8513 0.8498 0.7077 0.8561
Cytoplasmic Foci 0.0158 0.0031 0.0084 0.0037 0.0055 0.0044 0.025 0.0031 0.0118 0.0167 0.0035 0.0055 0.0439 0.004 0.0178 0.0297 0.015 0.0147
Eisosomes 0.0005 0 0 0 0 0 0.0002 0 0.0001 0 0 0 0.0001 0 0 0 0.0002 0
Endoplasmic Reticulum 0.0191 0.0031 0.0034 0.0041 0.0023 0.0028 0.0094 0.0037 0.0031 0.0028 0.0117 0.0035 0.0071 0.0024 0.0025 0.0018 0.0024 0.0027
Endosome 0.0897 0.0007 0.0021 0.0015 0.0014 0.0012 0.0276 0.0027 0.019 0.0358 0.0635 0.0138 0.0389 0.0007 0.0123 0.0202 0.027 0.0055
Golgi 0.019 0.0001 0.0012 0.0002 0.0001 0.0001 0.0086 0.0008 0.0064 0.0081 0.0022 0.0056 0.0072 0.0001 0.0038 0.0096 0.031 0.0008
Lipid Particles 0.0179 0.0001 0.0006 0.0001 0 0 0.0108 0.0009 0.0085 0.0004 0.0006 0.0037 0.0185 0 0.0053 0.0074 0.0172 0.0021
Mitochondria 0.028 0.0001 0.0004 0.0001 0.0001 0.0001 0.0031 0.0003 0.0082 0.0022 0.0022 0.0066 0.0028 0.0001 0.0019 0.0035 0.102 0.0019
None 0.1274 0.0649 0.0879 0.1078 0.083 0.1058 0.0137 0.0336 0.0104 0.01 0.006 0.0028 0.071 0.0299 0.0309 0.0234 0.0193 0.0279
Nuclear Periphery 0.0179 0.0011 0.0014 0.001 0.0008 0.001 0.0136 0.0024 0.0051 0.0025 0.0287 0.0033 0.0154 0.0017 0.003 0.0022 0.0031 0.0091
Nucleolus 0.0006 0 0 0 0 0 0.0005 0 0.0035 0.0002 0.0001 0.0011 0.0007 0.0001 0.0006 0.0006 0.0003 0.0022
Nucleus 0.0358 0.008 0.0117 0.0041 0.0065 0.0167 0.0262 0.0078 0.026 0.0094 0.008 0.0222 0.025 0.0216 0.0372 0.0223 0.0234 0.041
Peroxisomes 0.0062 0.0001 0.0111 0.0001 0.0001 0 0.0109 0.0002 0.0038 0.0012 0.0001 0.001 0.0128 0.0001 0.0089 0.0084 0.0105 0.0034
Punctate Nuclear 0.005 0.0007 0.001 0.0005 0.0014 0.0008 0.0048 0.0009 0.0022 0.0032 0.0008 0.0012 0.0132 0.0041 0.0025 0.0037 0.0021 0.0082
Vacuole 0.0068 0.0004 0.0005 0.0003 0.0004 0.0004 0.0028 0.0007 0.0019 0.0013 0.0037 0.003 0.0033 0.0005 0.0013 0.0028 0.0026 0.0018
Vacuole Periphery 0.0056 0 0.0001 0.0001 0.0001 0.0001 0.0016 0.0001 0.0009 0.0005 0.0048 0.0009 0.0015 0.0001 0.0003 0.0006 0.0025 0.0013

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 6.1155 4.6859 4.0566 12.8721 16.9906 5.2389 11.8447 13.8569 10.9889 13.5625
Translational Efficiency 2.1752 2.9221 3.8414 0.9961 0.9675 3.8731 1.5229 1.128 1.9559 1.7682

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1236 829 165 777 1283 247 362 560 2519 1076 527 1337

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 843.47 863.04 1175.61 970.76 809.78 918.29 1173.77 1063.89 826.31 875.72 1174.35 1009.77
Standard Deviation 102.89 124.08 130.26 190.91 113.23 116.19 132.82 151.19 109.58 124.50 132.02 181.29
Intensity Change Log 2 — 0.033091 0.479001 0.202778 — 0.181420 0.535548 0.393747 — 0.107650 0.506975 0.299476

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000161 0.000938 0.004109 0.001864 0.000456 0.000776 0.001392 0.012157 0.000311 0.000901 0.002243 0.006175
Bud Neck 0.003681 0.007613 0.008713 0.011071 0.002987 0.004539 0.005491 0.018646 0.003328 0.006908 0.006500 0.014244
Bud Site 0.003006 0.014827 0.017861 0.038475 0.005037 0.015640 0.010026 0.041721 0.004040 0.015014 0.012479 0.039835
Cell Periphery 0.000161 0.000164 0.000535 0.000273 0.000174 0.000188 0.000347 0.000187 0.000167 0.000170 0.000406 0.000237
Cytoplasm 0.607572 0.592990 0.134859 0.505830 0.630798 0.463484 0.300945 0.342390 0.619401 0.563261 0.248944 0.437373
Cytoplasmic Foci 0.142590 0.130715 0.011354 0.012447 0.093868 0.136469 0.007636 0.043333 0.117774 0.132036 0.008800 0.025383
Eisosomes 0.000086 0.000073 0.000100 0.000049 0.000058 0.000109 0.000100 0.000064 0.000072 0.000081 0.000100 0.000056
Endoplasmic Reticulum 0.001366 0.002269 0.021500 0.004943 0.002107 0.001712 0.009794 0.003545 0.001743 0.002141 0.013459 0.004357
Endosome 0.005015 0.008244 0.003362 0.008811 0.003621 0.009044 0.003940 0.036004 0.004305 0.008428 0.003759 0.020201
Golgi 0.001356 0.002216 0.000240 0.001142 0.000855 0.006265 0.000149 0.033677 0.001101 0.003145 0.000177 0.014769
Lipid Particles 0.002622 0.003448 0.002795 0.001623 0.002049 0.005531 0.002805 0.001913 0.002330 0.003926 0.002802 0.001744
Mitochondria 0.001356 0.001823 0.001251 0.000804 0.003547 0.009063 0.000532 0.019507 0.002472 0.003485 0.000757 0.008637
Mitotic Spindle 0.002636 0.007046 0.001769 0.027468 0.002268 0.007424 0.002762 0.074794 0.002449 0.007133 0.002451 0.047290
None 0.002942 0.003262 0.001678 0.008245 0.004092 0.000958 0.013276 0.003504 0.003528 0.002733 0.009645 0.006259
Nuclear Periphery 0.000277 0.000342 0.002413 0.000998 0.000300 0.000530 0.002261 0.001188 0.000289 0.000385 0.002308 0.001077
Nuclear Periphery Foci 0.001499 0.002687 0.003795 0.003734 0.002192 0.002073 0.004364 0.004424 0.001852 0.002546 0.004186 0.004023
Nucleolus 0.000312 0.001420 0.000305 0.000300 0.000334 0.001135 0.000389 0.006062 0.000323 0.001354 0.000363 0.002713
Nucleus 0.162648 0.134118 0.636312 0.238001 0.200402 0.153651 0.397517 0.112932 0.181877 0.138602 0.472282 0.185616
Peroxisomes 0.001360 0.004837 0.000514 0.001599 0.000956 0.006482 0.000714 0.008479 0.001154 0.005215 0.000651 0.004481
Vacuole 0.058776 0.080164 0.146296 0.131987 0.043393 0.171498 0.235375 0.215830 0.050941 0.101130 0.207485 0.167104
Vacuole Periphery 0.000579 0.000802 0.000237 0.000337 0.000507 0.003428 0.000184 0.019644 0.000542 0.001405 0.000201 0.008424

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.96 -4.05 -6.65 -2.04 2.75 -0.81 -3.66 -1.77 -1.60 -1.08 -3.29 -5.67 -2.86 -1.95 0.34
Bud Neck -3.33 -5.94 -3.57 -0.16 2.28 -2.07 -5.29 -2.97 -1.83 0.82 -4.07 -7.23 -4.77 -0.62 1.67
Bud Site -7.61 -3.36 -5.86 -1.65 -0.25 -2.23 -3.36 -5.07 -0.54 -2.44 -6.67 -5.02 -7.49 -1.73 -2.16
Cell Periphery -0.55 -9.18 -4.51 -4.03 6.17 -0.16 -5.08 1.59 1.24 7.72 -0.16 -9.98 -2.80 -2.61 7.39
Cytoplasm 2.15 40.70 23.92 18.96 -16.10 9.82 36.91 27.84 8.31 -5.86 6.99 50.10 36.36 21.98 -13.56
Cytoplasmic Foci 1.85 23.60 29.31 21.47 -0.25 -2.98 23.94 19.83 11.32 -4.77 -1.83 35.40 35.09 23.95 -3.29
Eisosomes 1.73 -3.03 3.59 1.60 5.23 -3.45 -6.56 -1.25 3.07 6.18 -1.99 -6.54 1.70 3.29 7.74
Endoplasmic Reticulum -3.70 -12.04 -11.49 -7.36 9.31 0.56 -12.93 -2.19 -3.01 12.30 -2.05 -17.58 -9.80 -7.16 13.68
Endosome -3.74 3.19 2.06 4.23 0.67 -5.02 0.12 -2.50 0.53 -2.56 -5.84 2.46 -0.59 3.17 -1.42
Golgi -0.83 2.63 2.37 2.25 -0.35 -1.80 1.70 -2.35 -0.31 -2.71 -1.97 3.12 -1.69 0.03 -2.75
Lipid Particles -0.88 -2.02 0.26 0.96 2.12 -1.04 -3.45 0.50 1.10 5.22 -1.52 -3.79 0.24 1.58 4.15
Mitochondria -0.42 -0.14 0.97 1.57 4.20 -1.06 2.24 -0.23 0.96 -2.72 -0.48 2.16 0.43 0.89 -2.31
Mitotic Spindle -1.72 0.65 -5.16 -3.82 -5.53 -1.29 -2.03 -5.71 -3.78 -5.06 -2.26 -1.65 -7.70 -5.61 -7.06
None -0.15 2.51 -2.78 -2.42 -6.64 6.44 -1.39 -0.49 -6.36 1.05 1.30 -0.90 -2.57 -3.37 -0.95
Nuclear Periphery -2.35 -16.40 -12.61 -11.94 3.57 -4.96 -18.38 -15.44 -11.52 7.14 -3.99 -23.78 -18.03 -16.46 6.99
Nuclear Periphery Foci -4.53 -4.56 -6.51 -1.29 0.48 -0.22 -3.95 -0.83 -0.52 1.94 -2.66 -6.45 -3.51 -1.03 2.25
Nucleolus -1.52 -0.64 0.92 1.58 1.68 -1.02 -0.59 -1.28 -0.11 -1.24 -1.76 -1.01 -1.19 0.97 -1.09
Nucleus 3.62 -21.77 -13.36 -15.50 14.86 3.52 -15.74 1.29 -2.14 15.01 6.78 -24.64 -9.21 -13.46 17.92
Peroxisomes -4.83 2.98 3.45 6.37 0.59 -3.03 2.21 -1.05 2.22 -1.79 -5.95 3.82 0.41 5.61 -1.60
Vacuole -5.56 -9.26 -22.99 -18.79 -5.29 -10.85 -18.80 -27.33 -11.30 -5.44 -11.82 -20.28 -35.09 -24.05 -5.10
Vacuole Periphery -0.63 1.26 1.61 3.56 3.25 -1.13 2.15 -2.74 -0.33 -3.05 -1.37 2.29 -2.15 -0.53 -2.97
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Pho85p cyclin of the Pho80p subfamily; forms the major Glc8p kinase together with Pcl7p and Pho85p; involved in the control of glycogen storage by Pho85p; stabilized by Elongin C binding; PCL6 has a paralog, PCL7, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (92%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Pcl6

Pcl6


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pcl6-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available