Standard name
Human Ortholog
Description Protein that associates with mitochondrial ribosome; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; null mutation results in a decrease in plasma membrane electron transport
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.08 0 0 0 0 – 0 0 0 0 0.08 0.08 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0.05 0 0 0 – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0 0 – – – – – –
Cell Periphery 0 0.05 0.06 0 0 0 0 – 0 0 0 0 0 0.06 0.05 – 0.1 0.05 0 0 0 0 0 0
Cytoplasm 0 0 0.06 0.06 0.06 0 0 – 0 0 0 0 0.13 0.23 0.22 – 0.09 0.1 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0.05 0 – 0.06 0.05 0 0 0 0 0 0
Endosome 0 0.09 0.1 0 0.12 0.05 0.06 – 0 0 0 0 0.12 0.14 0.26 – 0.17 0.1 0.1 0.08 0.09 0.05 0.05 0.05
Golgi 0 0.08 0.2 0.05 0.05 0 0 – 0 0 0 0 0.13 0.07 0.05 – 0.14 0.26 0.05 0.08 0 0.06 0.05 0.05
Mitochondria 0.94 0.78 0.44 0.85 0.65 0.8 0.78 – 0.89 0.9 0.95 0.92 0.49 0.34 0.18 – 0.16 0.08 0.74 0.7 0.7 0.73 0.74 0.73
Nucleus 0 0 0 0 0 0 0.05 – 0 0 0 0 0 0 0 – 0 0.05 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0.05 0 0 0 0 0 – 0 0 0 0 0.07 0.11 0.28 – 0.09 0 0.06 0 0.09 0 0 0
SpindlePole 0 0 0.1 0.05 0.07 0.05 0.08 – 0.05 0.06 0 0.07 0 0 0.07 – 0.13 0.13 0 0 0 0 0 0
Vac/Vac Membrane 0.11 0.13 0.19 0 0.08 0.06 0.08 – 0.07 0.07 0 0.05 0.1 0.1 0.11 – 0.25 0.31 0 0 0 0 0.05 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 8 17 4 8 2 3 – 0 3 0 3 15 18 1 – 2 0 7 14 4 6 7 9
Bud 5 15 2 7 6 9 6 – 14 9 9 12 4 6 3 – 3 0 0 2 1 0 2 3
Bud Neck 0 0 0 0 1 0 0 – 0 1 0 0 0 0 0 – 0 0 0 1 1 0 1 2
Bud Site 0 0 1 0 0 0 3 – 1 1 4 3 0 0 0 – 0 0 – – – – – –
Cell Periphery 11 24 13 2 4 4 5 – 3 4 1 5 5 14 13 – 11 2 0 1 1 0 0 0
Cytoplasm 4 9 14 9 13 10 16 – 14 9 6 14 24 53 62 – 10 4 0 0 0 1 4 5
Endoplasmic Reticulum 6 12 9 5 8 10 9 – 1 1 8 7 7 11 10 – 7 2 0 2 1 0 0 5
Endosome 14 45 23 2 25 15 26 – 14 7 0 6 22 34 74 – 19 4 42 49 32 11 15 19
Golgi 2 43 45 7 11 2 3 – 4 0 0 2 23 17 13 – 16 10 21 50 12 12 16 20
Mitochondria 375 399 96 128 132 221 320 – 278 306 292 369 87 79 51 – 18 3 312 429 258 158 235 296
Nucleus 1 5 1 4 3 7 20 – 5 5 4 4 2 0 0 – 2 2 0 0 0 0 2 0
Nuclear Periphery 8 7 1 0 3 8 8 – 4 3 5 6 0 1 1 – 1 0 0 5 2 1 1 3
Nucleolus 7 8 0 0 0 4 3 – 1 2 5 5 2 0 1 – 1 1 0 3 1 0 0 0
Peroxisomes 10 27 8 4 8 6 7 – 5 3 0 3 13 26 79 – 10 1 23 24 33 9 13 18
SpindlePole 6 9 21 8 15 13 33 – 15 20 9 28 7 9 19 – 15 5 0 2 2 2 0 0
Vac/Vac Membrane 46 66 42 5 17 17 32 – 22 24 13 19 18 24 31 – 28 12 9 20 12 7 14 15
Unique Cell Count 401 513 220 151 204 275 411 313 341 306 402 178 235 283 112 39 422 614 369 217 320 405
Labelled Cell Count 495 677 293 185 254 328 494 381 398 356 486 229 292 358 143 46 422 614 369 217 320 405


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.1 6.2 6.5 5.5 6.1 5.2 5.4 – 4.9 4.9 4.2 4.7 6.6 6.5 6.4 – 7.6 7.1 6.1 6.3 6.4
Std Deviation (1e-4) 0.6 0.9 1.0 1.4 1.1 1.3 1.1 – 1.4 1.0 0.8 0.9 1.4 1.3 1.2 – 1.5 1.5 1.1 1.2 1.2
Intensity Change (Log2) – – – -0.24 -0.09 -0.31 -0.26 – -0.39 -0.41 -0.63 -0.45 0.02 0.0 -0.02 – 0.22 0.14 -0.08 -0.03 -0.01

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -2.1 -1.7 -4.0 -4.8 – -5.0 0 0 0 0.3 0 -4.4 – -2.2 0
Bud 0 0 0 0 – 2.4 0 0 0 0 0 0 – 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 – 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 – 0 0
Cell Periphery -2.2 -2.1 -2.7 -3.4 – -3.3 0 0 0 -1.5 0 -0.7 – 1.3 0
Cytoplasm -0.2 0 -1.4 -1.4 – -1.0 -2.2 -2.6 -1.7 2.4 4.9 4.8 – 0.9 0
Endoplasmic Reticulum -0.4 -0.1 -0.3 -1.4 – 0 0 0 0 -0.1 0.3 -0.3 – 0.9 0
Endosome -3.4 0.6 -2.1 -1.8 – -2.7 0 0 0 0.6 1.3 4.4 – 1.7 0
Golgi -4.3 -4.6 -7.4 -8.9 – -7.5 0 0 0 -2.0 -4.1 -5.5 – -1.4 0.7
Mitochondria 8.0 4.3 8.5 8.6 – 11.2 0 0 0 1.0 -2.2 -6.3 – -5.0 -4.3
Nucleus 0 0 0 2.9 – 0 0 0 0 0 0 0 – 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 – 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 – 0 0
Peroxisomes 0 0.2 -1.0 -1.5 – -1.5 0 0 0 1.6 3.0 7.1 – 2.0 0
SpindlePole -1.5 -0.8 -2.1 -0.6 – -2.2 0 0 0 -2.2 -2.5 -1.2 – 1.1 0
Vacuole -4.5 -3.2 -4.4 -4.2 – -4.2 -4.3 -5.5 -5.8 -2.5 -2.7 -2.6 – 1.2 1.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.9837 1.08 0.8654 0.4851 1.0411 0.9395 1.8003 1.7609 1.754 1.674 2.3714 1.7754 2.1877 2.0972 1.8857 2.3674 1.6606 2.0548
Actin 0.0414 0.0384 0.0192 0.0237 0.0028 0.0027 0.0144 0.0076 0.0068 0.0007 0.0108 0.0122 0.0029 0.0014 0.0021 0.002 0.0014 0.0048
Bud 0.0009 0.0026 0.0013 0.0019 0.0003 0.0004 0.0005 0.0019 0.001 0.0002 0.001 0.0004 0.0021 0.0011 0.0003 0.0001 0.0003 0.0017
Bud Neck 0.0035 0.0037 0.0034 0.0004 0.0003 0.0005 0.0008 0.001 0.0009 0.0001 0.001 0.0016 0.0004 0.0012 0.0007 0.0001 0.0002 0.0008
Bud Periphery 0.0015 0.0035 0.0034 0.0045 0.0013 0.0012 0.0012 0.0033 0.0016 0.0007 0.003 0.0009 0.0013 0.0018 0.001 0.0005 0.0008 0.0014
Bud Site 0.0125 0.0343 0.0103 0.0009 0.0004 0.0006 0.0027 0.0233 0.0073 0.0004 0.0035 0.0009 0.0019 0.0078 0.001 0.0002 0.0005 0.001
Cell Periphery 0.0011 0.0026 0.0019 0.0006 0.0004 0.0004 0.0005 0.0018 0.0004 0.0001 0.0007 0.0009 0.0003 0.0004 0.0002 0.0002 0.0001 0.0009
Cytoplasm 0.0088 0.0053 0.0123 0.0044 0.0004 0.0002 0.0048 0.008 0.0047 0.0008 0.0022 0.0031 0.0016 0.0027 0.0014 0.0003 0.0004 0.0022
Cytoplasmic Foci 0.0415 0.0352 0.0343 0.0097 0.0131 0.0046 0.0412 0.036 0.0266 0.0037 0.037 0.0192 0.0148 0.0194 0.0147 0.0055 0.012 0.0204
Eisosomes 0.0012 0.0008 0.001 0.0005 0.0002 0.0002 0.0005 0.0007 0.0003 0.0001 0.0006 0.0002 0.0002 0.0002 0.0001 0.0004 0.0001 0.0002
Endoplasmic Reticulum 0.0077 0.0042 0.0012 0.0027 0.0003 0.0004 0.0015 0.003 0.0005 0.0003 0.0041 0.0003 0.001 0.0005 0.0004 0.0001 0.0001 0.0002
Endosome 0.0888 0.0669 0.0447 0.0718 0.0844 0.0283 0.0807 0.0497 0.052 0.0352 0.1126 0.0237 0.0539 0.0521 0.0326 0.0055 0.0256 0.0311
Golgi 0.0549 0.0726 0.0556 0.0409 0.1027 0.0354 0.0714 0.0477 0.0419 0.0076 0.0698 0.0391 0.0493 0.0663 0.0349 0.0086 0.0797 0.0453
Lipid Particles 0.0745 0.0346 0.0178 0.0508 0.0235 0.0165 0.0584 0.0215 0.0152 0.003 0.0315 0.0075 0.0246 0.0123 0.0128 0.005 0.0055 0.0121
Mitochondria 0.5471 0.6259 0.7491 0.7693 0.7548 0.875 0.604 0.7023 0.7912 0.9284 0.6547 0.8476 0.7963 0.7804 0.8582 0.9183 0.8329 0.8254
None 0.0163 0.002 0.0065 0.0006 0.0003 0.0001 0.0241 0.0019 0.0051 0.0003 0.0047 0.0014 0.0008 0.0038 0.0004 0.0014 0.0001 0.0017
Nuclear Periphery 0.0074 0.0033 0.0005 0.0012 0.0001 0.0002 0.001 0.001 0.0003 0.0019 0.0064 0.0001 0.001 0.0002 0.0002 0.0001 0 0.0002
Nucleolus 0.0011 0.0005 0.0008 0.0001 0.0002 0.0002 0.0008 0.0006 0.0007 0.0004 0.004 0.0002 0.0015 0.0021 0.0004 0.0001 0.0001 0.0033
Nucleus 0.0014 0.0006 0.0009 0.0002 0.0002 0.0002 0.0007 0.0006 0.0007 0.001 0.0033 0.0002 0.0007 0.0008 0.0004 0.0001 0.0001 0.0005
Peroxisomes 0.0591 0.0462 0.0261 0.0082 0.0096 0.0255 0.0816 0.0793 0.0338 0.0087 0.0353 0.0374 0.0379 0.0387 0.03 0.0504 0.0383 0.0412
Punctate Nuclear 0.0034 0.0003 0.0008 0.0002 0.0001 0 0.0018 0.0005 0.0005 0.0007 0.0018 0.0003 0.0006 0.0006 0.0011 0 0 0.0009
Vacuole 0.018 0.0094 0.0054 0.0038 0.0021 0.003 0.0045 0.0054 0.0062 0.0036 0.007 0.0016 0.0035 0.0032 0.0036 0.0005 0.0006 0.0025
Vacuole Periphery 0.0079 0.0071 0.0036 0.0036 0.0026 0.0044 0.0028 0.0028 0.0023 0.0021 0.0051 0.0014 0.0035 0.0032 0.0036 0.0008 0.0011 0.0021

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 4.8044 7.158 6.0198 7.8413 6.5751 2.1341 9.2881 11.3979 8.0745 9.3656
Translational Efficiency 1.2627 1.1697 1.2312 0.8354 0.6401 1.9905 0.7625 0.7156 0.7517 0.8262

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
94 1295 1820 1269 1647 1487 970 147 1741 2782 2790 1416

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 777.88 737.10 830.41 903.68 707.01 758.73 937.37 989.92 710.84 748.66 867.60 912.63
Standard Deviation 117.67 107.88 106.12 131.12 89.65 106.34 123.38 132.12 92.77 107.60 123.42 133.83
Intensity Change Log 2 — -0.077687 0.094276 0.216264 — 0.101856 0.406888 0.485581 — 0.010590 0.251583 0.350776

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000626 0.001244 0.004634 0.046308 0.000986 0.001873 0.014169 0.027676 0.000966 0.001580 0.007949 0.044374
Bud Neck 0.006649 0.004775 0.004375 0.003552 0.003662 0.001937 0.001719 0.003218 0.003823 0.003258 0.003451 0.003517
Bud Site 0.004618 0.012654 0.025610 0.070908 0.007472 0.006516 0.021557 0.054781 0.007318 0.009373 0.024201 0.069234
Cell Periphery 0.000284 0.000433 0.000242 0.001264 0.000348 0.000268 0.000522 0.000675 0.000344 0.000344 0.000339 0.001202
Cytoplasm 0.002437 0.003642 0.023548 0.011188 0.002995 0.002149 0.004469 0.012827 0.002965 0.002844 0.016914 0.011358
Cytoplasmic Foci 0.060454 0.041089 0.046305 0.039249 0.041197 0.047846 0.084087 0.068536 0.042237 0.044701 0.059440 0.042289
Eisosomes 0.000077 0.000082 0.000077 0.000214 0.000078 0.000085 0.000142 0.000174 0.000078 0.000084 0.000100 0.000210
Endoplasmic Reticulum 0.000435 0.000381 0.002012 0.001078 0.000249 0.000572 0.002476 0.001921 0.000259 0.000483 0.002174 0.001166
Endosome 0.070431 0.081515 0.081373 0.047292 0.074826 0.084384 0.086030 0.116582 0.074589 0.083049 0.082992 0.054485
Golgi 0.064451 0.114650 0.079957 0.097321 0.121162 0.144564 0.181986 0.185004 0.118100 0.130640 0.115429 0.106424
Lipid Particles 0.021062 0.002280 0.001512 0.000361 0.002090 0.001914 0.001115 0.000296 0.003114 0.002084 0.001374 0.000354
Mitochondria 0.591412 0.651550 0.563035 0.559573 0.687413 0.635216 0.482668 0.339783 0.682230 0.642820 0.535094 0.536756
Mitotic Spindle 0.012844 0.012127 0.060117 0.036039 0.006520 0.010951 0.030190 0.048997 0.006861 0.011498 0.049712 0.037385
None 0.000601 0.000268 0.000288 0.000227 0.000217 0.000216 0.000197 0.000281 0.000238 0.000241 0.000256 0.000232
Nuclear Periphery 0.000163 0.000105 0.000600 0.000082 0.000061 0.000068 0.000199 0.000348 0.000066 0.000085 0.000461 0.000110
Nuclear Periphery Foci 0.000369 0.000211 0.001095 0.000617 0.000124 0.000111 0.000406 0.000557 0.000137 0.000157 0.000855 0.000611
Nucleolus 0.014761 0.000671 0.000685 0.000040 0.000143 0.000740 0.000043 0.000054 0.000933 0.000708 0.000462 0.000041
Nucleus 0.004739 0.000797 0.004276 0.000252 0.000379 0.001037 0.000453 0.000156 0.000614 0.000925 0.002947 0.000242
Peroxisomes 0.129510 0.044640 0.039976 0.068392 0.029307 0.036889 0.047234 0.042467 0.034717 0.040497 0.042499 0.065700
Vacuole 0.006046 0.011548 0.038844 0.010305 0.008201 0.010499 0.018743 0.064182 0.008084 0.010987 0.031855 0.015898
Vacuole Periphery 0.008031 0.015338 0.021439 0.005737 0.012572 0.012166 0.021598 0.031484 0.012326 0.013642 0.021495 0.008410

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.47 -5.85 -12.30 -12.13 -11.05 -2.36 -7.28 -3.30 -3.19 -1.62 -2.25 -8.75 -12.61 -12.44 -10.35
Bud Neck 0.95 1.16 1.61 1.27 1.39 2.16 2.62 0.39 -1.34 -1.62 0.73 0.39 0.29 -0.57 -0.10
Bud Site -4.57 -9.64 -15.39 -13.32 -9.82 0.72 -6.17 -5.07 -5.18 -3.47 -1.67 -9.91 -15.60 -15.24 -10.88
Cell Periphery -1.50 0.48 -5.94 -5.47 -7.04 1.35 -2.07 -2.85 -3.83 -1.25 -0.00 0.10 -6.27 -6.54 -6.57
Cytoplasm -1.00 -8.35 -7.26 -7.03 5.54 1.76 -1.92 -2.50 -2.72 -2.11 0.24 -8.60 -9.56 -9.67 3.97
Cytoplasmic Foci 1.98 1.44 2.15 0.63 2.50 -2.27 -10.65 -3.39 -2.55 1.87 -0.96 -6.61 0.05 0.97 6.35
Eisosomes -0.46 0.01 -10.38 -13.95 -14.45 -0.62 -5.05 -3.33 -3.25 -1.09 -0.55 -2.12 -10.36 -14.18 -12.08
Endoplasmic Reticulum 0.47 -3.29 -3.41 -4.14 1.89 -1.19 -3.09 -3.46 -2.45 0.65 -1.50 -4.80 -5.71 -3.28 2.38
Endosome -0.81 -0.75 1.75 7.86 8.66 -2.10 -2.42 -3.68 -2.82 -2.68 -2.16 -2.06 5.15 8.21 8.31
Golgi -4.26 -1.28 -2.79 2.71 -3.30 -3.50 -7.56 -3.64 -2.26 -0.14 -2.31 0.66 1.96 4.34 1.53
Lipid Particles 2.25 2.34 2.48 4.98 3.60 0.26 1.67 3.23 4.51 4.69 1.37 2.33 3.91 6.40 4.55
Mitochondria -1.43 0.81 0.74 6.60 -0.19 4.24 14.27 12.00 10.12 4.73 3.75 14.14 11.42 9.01 -0.44
Mitotic Spindle 0.22 -10.43 -5.93 -8.37 5.78 -2.96 -7.38 -4.32 -3.85 -1.82 -3.88 -16.48 -11.92 -9.83 3.63
None 2.25 2.08 2.59 1.67 3.35 0.06 0.63 -1.03 -0.93 -1.93 -0.02 -0.56 0.25 0.33 1.96
Nuclear Periphery 0.90 -2.63 1.19 0.63 3.30 -0.50 -4.04 -1.53 -1.49 -0.78 -1.22 -3.85 -1.48 -0.84 3.31
Nuclear Periphery Foci 1.40 -2.12 -0.57 -0.94 0.90 0.44 -3.60 -2.36 -2.44 -0.70 -0.66 -3.28 -1.22 -1.16 0.58
Nucleolus 1.44 1.44 1.51 1.82 2.58 -1.71 3.41 2.72 1.98 -0.45 0.37 0.80 1.67 2.71 2.58
Nucleus 1.61 -0.11 1.82 1.96 5.39 -1.48 -0.40 1.78 2.08 1.46 -1.01 -4.71 1.70 2.43 5.44
Peroxisomes 3.62 3.84 2.60 -4.21 -5.53 -2.01 -3.76 -1.30 -0.53 0.50 -1.66 -2.22 -6.42 -5.41 -4.97
Vacuole -3.14 -13.21 -2.58 0.30 11.89 -1.90 -6.01 -4.57 -4.38 -3.64 -3.12 -15.10 -4.62 -3.07 7.07
Vacuole Periphery -3.28 -6.10 1.20 6.87 12.02 0.29 -4.47 -3.26 -3.30 -1.64 -1.15 -7.15 3.52 4.52 10.15
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein that associates with mitochondrial ribosome; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; null mutation results in a decrease in plasma membrane electron transport
Localization
Cell Percentages mitochondrion (99%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Mrx1

Mrx1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mrx1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available