Standard name
Human Ortholog
Description Activator of Cbk1p kinase; component of the RAM signaling network that regulates cellular polarity and morphogenesis; activation of Cbk1p facilitates the Ace2p-dependent daughter cell-specific transcription of genes involved in cell separation; similar to Mob1p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.16 – 0.06 0.09 0 0 0 0 0 0 0 0 0.05 0 0 0.12 0.12 0.18 0.13 0.19 0.07 0.15 0.19 0.19
Bud 0.09 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.09 0.08 0.06 0.06 0.18 0.14 0.14
Bud Neck 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.16 0.15 0.24 0.39 0.3 0.14
Bud Site 0.07 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.1 – 0.06 0.09 0.05 0 0 0 0 0 0 0 0.11 0.2 0.16 0.18 0.3 0.3 0.12 0.05 0.07 0 0 0
Cytoplasm 0.74 – 0.94 0.79 0.83 0.81 0.9 0.9 0.87 0.94 0.84 0.93 0.84 0.98 0.99 0.76 0.62 0.62 0.36 0.41 0.43 0.14 0.27 0.43
Endoplasmic Reticulum 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
Endosome 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0.05 – 0 0.08 0.11 0.16 0.05 0 0.05 0 0 0 0.11 0 0 0 0.08 0 0 0 0 0 0 0
Vac/Vac Membrane 0 – 0 0 0 0 0 0 0 0 0.08 0.05 0 0 0 0 0.07 0.05 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 29 – 1 27 16 13 6 9 2 5 1 1 2 3 4 28 39 57 28 6 3 25 46 53
Bud 16 – 0 7 5 5 11 15 11 6 6 3 1 4 2 9 26 28 16 2 3 31 33 39
Bud Neck 1 – 0 9 17 11 9 18 11 2 1 1 0 3 1 0 9 1 33 5 12 65 73 41
Bud Site 13 – 0 3 9 3 1 0 0 3 1 1 1 1 0 3 5 7 – – – – – –
Cell Periphery 19 – 1 25 23 4 16 12 8 3 3 8 4 57 55 43 100 94 26 1 3 6 7 8
Cytoplasm 135 – 16 230 422 287 548 556 451 374 165 249 31 284 334 178 209 193 75 13 22 24 66 124
Endoplasmic Reticulum 3 – 0 4 0 0 0 2 0 1 0 0 0 1 3 13 14 10 8 0 0 2 4 2
Endosome 2 – 0 1 1 5 4 1 9 1 1 2 0 0 0 3 6 4 4 0 0 3 1 3
Golgi 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 0 0 0 0 0
Mitochondria 6 – 0 0 1 1 5 8 9 5 4 2 0 0 0 2 4 1 5 0 2 2 1 2
Nucleus 0 – 0 3 5 4 7 3 3 2 0 2 0 1 0 1 7 0 0 0 0 0 0 1
Nuclear Periphery 0 – 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 – 0 1 2 1 2 3 9 1 1 2 0 0 0 1 4 0 0 0 0 0 0 0
Peroxisomes 6 – 0 2 2 2 1 0 1 0 1 0 0 0 0 0 1 1 0 0 0 0 0 0
SpindlePole 9 – 0 22 55 56 29 23 26 11 7 6 4 2 0 10 27 14 0 0 2 2 2 1
Vac/Vac Membrane 0 – 0 6 6 3 24 5 22 5 15 14 0 0 0 6 24 15 9 0 0 2 1 1
Unique Cell Count 182 17 290 506 355 609 617 518 400 196 269 37 290 339 234 337 312 209 33 53 170 245 286
Labelled Cell Count 239 18 341 565 395 663 655 562 419 206 291 43 356 399 297 477 427 209 33 53 170 245 286


Cell Periphery, Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.8 – 5.9 7.6 6.9 6.2 6.0 5.8 5.6 5.5 6.9 6.0 7.3 7.1 6.8 9.4 10.3 11.2 6.6 7.2 7.4
Std Deviation (1e-4) 1.0 – 0.6 7.2 1.8 7.4 5.5 1.2 1.2 1.0 4.2 1.2 1.2 1.5 1.2 1.8 2.0 2.0 1.3 1.2 1.5
Intensity Change (Log2) – – – 0.38 0.24 0.09 0.03 -0.02 -0.06 -0.08 0.23 0.04 0.32 0.28 0.22 0.69 0.82 0.94 0.17 0.29 0.33

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -1.5 -1.2 -1.4 -0.6 -0.5 -0.9 -0.1 -1.1 -0.2 -1.0 1.0 1.4 -1.7 -2.7 -2.7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.805 2.4079 2.085 1.6769 1.7861 2.3802 1.6409 2.5185 2.3757 1.8601 2.0315 2.2766 1.4677 2.3262 1.819 2.3185 1.1043 1.8283
Actin 0.0156 0.0088 0.031 0.0118 0.0482 0.0198 0.0323 0.007 0.0212 0.027 0.046 0.0132 0.0186 0.0104 0.0369 0.1526 0.1203 0.0243
Bud 0.0049 0.004 0.0329 0.0139 0.0115 0.0062 0.0014 0.0017 0.0186 0.0065 0.0098 0.0027 0.0044 0.0014 0.0184 0.0433 0.0313 0.0016
Bud Neck 0.0235 0.0021 0.0107 0.0235 0.0049 0.4128 0.0203 0.006 0.0056 0.0022 0.0018 0.6708 0.02 0.0026 0.0103 0.0026 0.0759 0.6659
Bud Periphery 0.0291 0.0068 0.0837 0.1198 0.0592 0.0122 0.013 0.004 0.0793 0.0832 0.1784 0.0263 0.021 0.0017 0.0683 0.1979 0.1312 0.0084
Bud Site 0.0787 0.1913 0.0615 0.0324 0.0069 0.007 0.0455 0.1892 0.0282 0.008 0.002 0.0013 0.0601 0.108 0.039 0.0072 0.0131 0.0053
Cell Periphery 0.0407 0.0189 0.0225 0.0437 0.0485 0.0081 0.0509 0.0283 0.0298 0.0666 0.1335 0.0211 0.032 0.0196 0.0242 0.0213 0.0196 0.0083
Cytoplasm 0.5892 0.6313 0.6126 0.6289 0.5556 0.4103 0.6236 0.6394 0.7485 0.5502 0.2547 0.2416 0.6972 0.7531 0.7006 0.4924 0.4978 0.2456
Cytoplasmic Foci 0.0119 0.0088 0.0047 0.0038 0.008 0.0135 0.0114 0.0016 0.0023 0.0163 0.0136 0.0015 0.0214 0.0029 0.0107 0.0108 0.0155 0.0033
Eisosomes 0.0012 0.0004 0.0004 0.0014 0.001 0.0003 0.0006 0.0002 0.0003 0.0004 0.0008 0.0001 0.0007 0.0003 0.0005 0.0007 0.0004 0.0001
Endoplasmic Reticulum 0.008 0.0055 0.0036 0.006 0.0072 0.0027 0.0164 0.0032 0.0073 0.0206 0.0037 0.001 0.0071 0.0028 0.0065 0.0066 0.0034 0.0034
Endosome 0.009 0.0024 0.001 0.001 0.0114 0.0029 0.0082 0.0002 0.001 0.0293 0.0237 0.0052 0.0072 0.0003 0.0021 0.0055 0.0074 0.0006
Golgi 0.0026 0.001 0.001 0.0007 0.0087 0.0008 0.0052 0.0002 0.0013 0.0266 0.0184 0.004 0.0019 0.0003 0.0025 0.0102 0.0086 0.0004
Lipid Particles 0.0079 0.0008 0.0006 0.0005 0.003 0.0008 0.0118 0.0006 0.0022 0.0255 0.0284 0.0011 0.0045 0.0006 0.0042 0.0157 0.0154 0.0009
Mitochondria 0.0009 0.0005 0.0016 0.0009 0.003 0.0006 0.016 0 0.0024 0.044 0.0763 0.001 0.0021 0.0001 0.0009 0.0028 0.0022 0.0001
None 0.1573 0.1096 0.1233 0.1033 0.2131 0.083 0.112 0.1159 0.0463 0.0607 0.0132 0.0068 0.0745 0.093 0.0602 0.007 0.0277 0.0246
Nuclear Periphery 0.0023 0.0006 0.0006 0.0008 0.0016 0.0034 0.0059 0.0003 0.0005 0.0036 0.0271 0.0005 0.0055 0.0003 0.0009 0.0018 0.0051 0.0001
Nucleolus 0.0017 0.0015 0.0016 0.0003 0.0003 0.0017 0.0004 0.0001 0.0002 0.0008 0.0041 0.0001 0.0016 0.0003 0.0003 0.0001 0.0006 0.0024
Nucleus 0.0074 0.0018 0.0028 0.0014 0.0017 0.005 0.0019 0.0006 0.0005 0.0017 0.0119 0.0005 0.0037 0.0006 0.0012 0.0008 0.0013 0.0023
Peroxisomes 0.0014 0.0002 0.0003 0.0006 0.001 0.0005 0.0179 0 0.0025 0.0162 0.0976 0.0004 0.0036 0 0.0074 0.0139 0.0068 0.0002
Punctate Nuclear 0.0022 0.0018 0.0015 0.0006 0.001 0.0062 0.0011 0.0002 0.0002 0.001 0.0521 0.0005 0.0098 0.0003 0.003 0.0041 0.0136 0.0005
Vacuole 0.0043 0.0017 0.0021 0.0045 0.0035 0.0018 0.0032 0.0012 0.0016 0.0061 0.0018 0.0004 0.0026 0.0014 0.0019 0.0024 0.0022 0.0017
Vacuole Periphery 0.0004 0.0001 0.0002 0.0003 0.0007 0.0003 0.0009 0 0.0001 0.0032 0.0012 0.0001 0.0006 0 0.0001 0.0003 0.0004 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 24.2647 13.6997 8.4715 23.0044 24.0091 21.6985 17.3147 15.9712 16.0636 22.8811
Translational Efficiency 1.8319 2.2542 2.6991 0.9192 1.1284 2.1621 1.5402 1.5866 1.6081 1.5495

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1706 1047 2100 1462 150 1176 1146 648 1856 2223 3246 2110

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 788.68 874.31 989.44 956.17 795.16 892.92 943.20 1051.77 789.20 884.15 973.11 985.53
Standard Deviation 85.37 104.95 108.45 156.40 95.11 115.05 131.33 161.03 86.22 110.80 119.11 163.88
Intensity Change Log 2 — 0.148705 0.327172 0.277827 — 0.167286 0.246319 0.403502 — 0.158063 0.287146 0.342290

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.003767 0.012131 0.009543 0.022125 0.003726 0.009434 0.010948 0.046575 0.003763 0.010705 0.010039 0.029634
Bud Neck 0.136151 0.132517 0.137306 0.073024 0.118529 0.198191 0.093498 0.043569 0.134727 0.167260 0.121840 0.063978
Bud Site 0.116636 0.256674 0.292725 0.348773 0.087551 0.283410 0.269235 0.328498 0.114286 0.270818 0.284432 0.342546
Cell Periphery 0.002245 0.005142 0.005724 0.003862 0.002484 0.006247 0.003262 0.009058 0.002265 0.005726 0.004854 0.005458
Cytoplasm 0.466444 0.351937 0.353492 0.370845 0.369168 0.343452 0.347958 0.353790 0.458583 0.347448 0.351538 0.365607
Cytoplasmic Foci 0.075335 0.097698 0.014929 0.017870 0.163097 0.042891 0.039567 0.027948 0.082428 0.068704 0.023628 0.020965
Eisosomes 0.002075 0.002085 0.000779 0.000647 0.002423 0.002870 0.000730 0.002103 0.002103 0.002501 0.000762 0.001094
Endoplasmic Reticulum 0.001544 0.005148 0.004696 0.001125 0.003056 0.002323 0.003167 0.002279 0.001666 0.003654 0.004156 0.001479
Endosome 0.008805 0.012599 0.001535 0.004559 0.018968 0.007746 0.004459 0.003439 0.009626 0.010032 0.002567 0.004215
Golgi 0.003264 0.005094 0.000330 0.002983 0.003942 0.004043 0.000600 0.003324 0.003319 0.004538 0.000426 0.003088
Lipid Particles 0.004482 0.004581 0.001047 0.001038 0.006000 0.002413 0.001841 0.002060 0.004605 0.003434 0.001327 0.001352
Mitochondria 0.001669 0.001587 0.000818 0.002497 0.002944 0.002296 0.000698 0.001102 0.001772 0.001962 0.000776 0.002068
Mitotic Spindle 0.000110 0.000455 0.002130 0.003117 0.000444 0.003844 0.002753 0.007154 0.000137 0.002248 0.002350 0.004357
None 0.001211 0.000499 0.000382 0.000454 0.000144 0.000403 0.000618 0.000264 0.001125 0.000448 0.000465 0.000396
Nuclear Periphery 0.000081 0.000048 0.000126 0.000123 0.000091 0.000049 0.000573 0.000098 0.000082 0.000049 0.000284 0.000115
Nuclear Periphery Foci 0.000509 0.000858 0.001017 0.000901 0.001050 0.000421 0.002610 0.001970 0.000553 0.000627 0.001580 0.001229
Nucleolus 0.000405 0.000132 0.000084 0.000152 0.000156 0.000155 0.000193 0.000059 0.000385 0.000144 0.000123 0.000124
Nucleus 0.060321 0.021370 0.064315 0.020248 0.035612 0.022989 0.045537 0.019109 0.058324 0.022227 0.057686 0.019898
Peroxisomes 0.003980 0.006396 0.001309 0.002161 0.008914 0.003983 0.002135 0.003653 0.004379 0.005119 0.001601 0.002619
Vacuole 0.110378 0.082200 0.107605 0.121906 0.170700 0.061650 0.169191 0.142732 0.115253 0.071329 0.129348 0.128302
Vacuole Periphery 0.000587 0.000849 0.000106 0.001592 0.001001 0.001188 0.000429 0.001215 0.000620 0.001028 0.000220 0.001476

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.90 -6.70 -8.96 -3.36 -5.59 -5.23 -4.96 -8.24 -6.86 -6.72 -8.99 -8.36 -12.03 -7.65 -8.65
Bud Neck 0.35 2.68 11.08 9.22 9.86 -4.11 2.04 4.41 18.19 6.97 -4.16 4.80 13.13 18.81 11.62
Bud Site -14.51 -17.66 -18.21 -2.42 -3.23 -13.10 -9.38 -10.61 1.57 -2.54 -21.50 -19.76 -21.08 -0.78 -4.21
Cell Periphery -5.81 -4.55 -2.42 3.57 2.78 -5.08 -0.58 -4.01 -0.67 -4.07 -8.74 -4.57 -4.88 2.70 -0.30
Cytoplasm 10.51 10.83 7.60 -3.02 -2.16 1.09 0.66 0.43 -1.05 -0.35 12.52 11.85 8.84 -3.48 -2.11
Cytoplasmic Foci -4.31 20.23 19.04 17.39 -1.65 9.15 9.40 10.24 4.33 3.91 3.63 19.37 20.29 17.36 2.41
Eisosomes -0.06 7.11 7.79 6.81 1.62 -0.87 3.54 1.29 2.96 -3.85 -1.58 7.89 6.12 7.39 -2.14
Endoplasmic Reticulum -5.05 -7.12 1.29 5.82 8.56 0.76 -0.50 0.67 -0.26 2.27 -4.38 -7.41 0.31 5.11 8.89
Endosome -3.31 11.47 4.83 6.85 -2.52 3.38 4.54 4.93 5.03 1.76 -0.53 10.86 6.98 7.58 -1.47
Golgi -3.21 10.43 1.10 2.83 -2.28 -0.15 3.00 0.98 1.36 -1.76 -2.38 10.55 1.40 2.78 -2.83
Lipid Particles -0.10 7.95 8.08 5.73 1.07 3.94 4.42 3.46 -0.68 -1.66 2.45 8.04 7.53 5.46 -0.43
Mitochondria 0.21 2.86 -0.31 -0.39 -1.48 0.29 1.21 1.08 2.77 -0.45 -0.58 3.60 0.34 0.67 -1.56
Mitotic Spindle -3.90 -4.01 -3.65 -3.13 -0.66 -2.18 -2.02 -2.30 -0.54 -1.21 -2.58 -4.42 -4.14 -1.05 -1.32
None 2.22 3.15 2.73 0.29 0.00 -3.23 -3.31 -1.05 1.18 2.18 2.72 2.71 2.97 0.47 1.00
Nuclear Periphery 2.16 -5.84 -1.49 -2.55 1.33 3.67 -1.36 -1.10 -2.27 1.22 2.29 -1.99 -1.84 -3.24 1.46
Nuclear Periphery Foci -4.05 -8.15 -2.78 -0.65 1.42 3.39 -6.19 -2.51 -3.76 0.96 -1.28 -11.27 -4.30 -3.90 1.92
Nucleolus 6.79 7.84 4.37 -0.00 -0.83 0.74 0.12 3.36 4.17 3.12 6.51 6.92 5.58 1.00 0.33
Nucleus 14.86 -5.25 12.39 -2.12 16.53 3.33 -3.86 1.76 -1.95 7.14 15.62 -4.05 12.71 -2.64 17.85
Peroxisomes -3.03 6.72 4.94 6.57 -2.30 1.84 2.65 2.21 1.34 -1.58 -1.14 6.76 4.70 6.26 -2.60
Vacuole 5.66 -6.19 -10.56 -13.75 -5.63 7.04 -2.43 -2.50 -15.50 -0.39 11.27 -10.78 -12.91 -21.16 -4.33
Vacuole Periphery -2.21 7.66 -1.71 -0.99 -3.06 -0.34 1.40 0.15 0.43 -0.81 -1.62 5.04 -1.54 -0.21 -2.88
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Activator of Cbk1p kinase; component of the RAM signaling network that regulates cellular polarity and morphogenesis; activation of Cbk1p facilitates the Ace2p-dependent daughter cell-specific transcription of genes involved in cell separation; similar to Mob1p
Localization
Cell Percentages cytoplasm (56%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-10

Mob2

Mob2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mob2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available