Standard name
Human Ortholog
Description Subunit 6 of the ubiquinol cytochrome-c reductase complex; the complex, also known as the cytochrome bc(1) complex or Complex III, is a component of the mitochondrial inner membrane electron transport chain; highly acidic protein; required for maturation of cytochrome c1; may be loosely associated with the complex since it is easily released into the intermembrane space
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery – 0 0 0 0 0 0 0 0 0.06 0.06 0.06 0 0 0 0 0.05 0.05 0 0 0 0 0 0
Cytoplasm – 0.98 1.0 0.97 0.98 0.91 0.84 0.77 0.73 0.75 0.75 0.73 0.97 0.96 0.97 0.98 0.93 0.97 1.0 0.95 0.95 0.84 0.83 0.76
Endoplasmic Reticulum – 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0.05 0 0 0 0 0.05 0 0
Endosome – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria – 0 0 0 0 0.07 0.12 0.07 0.16 0.09 0.18 0.21 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane – 0 0 0 0 0 0.06 0.14 0.12 0.14 0.1 0.08 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 0 0 0 0 0 0 0 1 5 1 2 0 0 0 0 0 0 0 0 0 0 2 3
Bud – 0 0 0 1 10 8 9 11 6 4 12 1 1 2 0 0 0 0 0 0 0 5 12
Bud Neck – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2
Bud Site – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery – 1 0 2 10 9 13 11 19 39 26 31 0 5 6 5 8 8 0 0 0 0 0 0
Cytoplasm – 159 51 260 567 341 487 367 330 515 305 403 112 233 285 209 136 152 7 151 61 62 172 227
Endoplasmic Reticulum – 1 0 1 3 7 13 2 13 31 11 18 1 3 5 6 7 6 0 0 2 4 3 7
Endosome – 0 0 1 0 0 0 0 0 0 1 0 0 4 1 0 0 1 0 0 0 1 5 6
Golgi – 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 0 0 1 0 0 0 2
Mitochondria – 2 0 2 11 26 67 35 71 61 74 114 0 0 0 2 0 1 0 1 0 1 1 4
Nucleus – 2 0 2 1 0 8 6 5 8 3 6 1 0 1 2 4 1 0 0 0 0 1 2
Nuclear Periphery – 0 0 1 0 0 1 2 3 1 4 3 0 0 0 0 0 0 0 0 0 0 0 1
Nucleolus – 0 0 1 0 0 0 3 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
SpindlePole – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 5
Vac/Vac Membrane – 1 0 3 4 9 35 68 56 94 42 44 2 5 3 1 4 5 0 1 0 0 7 12
Unique Cell Count 163 51 267 580 374 578 477 451 683 409 554 116 242 295 214 146 156 8 159 65 75 208 298
Labelled Cell Count 166 51 273 597 402 632 503 511 760 473 633 117 251 304 225 161 174 8 159 65 75 208 298


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) – 9.3 7.1 7.1 8.8 7.9 7.8 8.4 8.8 9.3 9.0 9.7 8.6 9.2 9.4 14.3 13.9 13.8 12.6 10.4 11.3
Std Deviation (1e-4) – 2.3 1.5 1.7 1.8 1.6 2.2 2.5 3.4 3.6 3.9 4.3 1.9 4.4 1.8 3.2 3.0 3.0 7.0 2.8 5.6
Intensity Change (Log2) – – – -0.02 0.3 0.14 0.12 0.24 0.3 0.38 0.34 0.44 0.26 0.36 0.4 1.0 0.96 0.95 0.82 0.55 0.67

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -1.2 -1.1 -2.2 -3.1 -3.9 -4.2 -4.0 -4.1 -4.3 -1.3 -1.4 -1.3 -1.1 -1.9 -1.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 2.6 0 3.1 0 3.3 3.6 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 2.9 2.7 2.8 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 8.6363 9.4432 9.8378 9.3791 8.9195 9.5801 7.3921 8.6469 7.3056 6.0233 5.9766 6.8051 7.6683 9.0742 8.5351 8.7652 7.2197 7.8362
Actin 0.0469 0.0005 0.0151 0.0047 0.0512 0.0029 0.0035 0.0008 0.0237 0.0063 0.0011 0.0004 0.0005 0.0003 0.0019 0.0001 0.0003 0.0003
Bud 0.0004 0.0004 0.0003 0.0003 0.0003 0.0003 0.0002 0.0001 0.0004 0.0001 0 0 0 0.0001 0.0006 0.0001 0.0001 0.0001
Bud Neck 0.0023 0.0002 0.0007 0.0016 0.0014 0.0014 0.0003 0.0002 0.0003 0.002 0.0004 0.0008 0.0001 0.0001 0.0003 0.0002 0.0004 0.0013
Bud Periphery 0.0005 0.0001 0.0002 0.0002 0.0003 0.0002 0.0001 0 0.0002 0.0001 0 0 0 0 0.0003 0 0 0.0001
Bud Site 0.0019 0.0065 0.0012 0.0007 0.0013 0.0001 0.0012 0.0002 0.0005 0.0005 0.0001 0 0.0001 0.0003 0.0014 0 0 0
Cell Periphery 0.0002 0.0001 0.0001 0.0001 0.0001 0 0.0003 0 0.0001 0.0001 0 0 0 0 0.0001 0 0 0
Cytoplasm 0.7964 0.9622 0.9145 0.8886 0.8375 0.9353 0.7887 0.9523 0.9202 0.9159 0.9271 0.9729 0.9627 0.9924 0.9715 0.9883 0.9928 0.9893
Cytoplasmic Foci 0.0222 0.0017 0.0076 0.0045 0.0116 0.0018 0.0269 0.0125 0.0025 0.0127 0.004 0.0016 0.0093 0.0007 0.0021 0.0008 0.0007 0.0014
Eisosomes 0.0003 0 0.0001 0.0001 0.0002 0 0.0005 0 0.0002 0.0002 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0112 0.0064 0.0097 0.0061 0.0063 0.0164 0.0069 0.0005 0.0045 0.0041 0.0028 0.0027 0.0057 0.0013 0.0016 0.0026 0.0014 0.0019
Endosome 0.0182 0.0007 0.0109 0.0101 0.0243 0.0027 0.0039 0.0003 0.0037 0.0038 0.003 0.0005 0.0018 0.0001 0.0004 0.0005 0.0002 0.0004
Golgi 0.004 0.0001 0.0029 0.0047 0.0074 0.0039 0.003 0.001 0.0024 0.0011 0.0002 0.0001 0.0002 0 0.0001 0 0 0
Lipid Particles 0.0043 0 0.0057 0.0058 0.011 0.0006 0.01 0.0007 0.0009 0.0035 0.0006 0 0.0002 0 0.0001 0 0 0
Mitochondria 0.0014 0.0001 0.0019 0.0216 0.0061 0.0049 0.0018 0.0001 0.002 0.0004 0.0001 0 0 0 0.0001 0 0 0
None 0.0269 0.016 0.0076 0.0023 0.0044 0.0161 0.0929 0.0015 0.0317 0.0373 0.0533 0.0191 0.0147 0.0028 0.0158 0.0026 0.0016 0.0016
Nuclear Periphery 0.0216 0.0013 0.0067 0.0188 0.0081 0.0028 0.0014 0.0002 0.0024 0.001 0.0019 0.0003 0.0015 0.0003 0.0006 0.001 0.0005 0.0005
Nucleolus 0.001 0 0.0001 0.0004 0.0005 0 0.0206 0 0.0002 0.0005 0.0001 0 0 0 0 0 0 0
Nucleus 0.0227 0.0027 0.0038 0.0155 0.0063 0.0083 0.009 0.0008 0.0017 0.0014 0.0019 0.0012 0.002 0.0011 0.0023 0.0031 0.0017 0.0025
Peroxisomes 0.0056 0 0.0074 0.0076 0.0113 0.0003 0.0255 0.0286 0.0003 0.0024 0.0001 0 0.0002 0 0.0001 0 0 0
Punctate Nuclear 0.0092 0.0004 0.0017 0.0035 0.0083 0.0003 0.0025 0.0002 0.0014 0.0062 0.0028 0.0001 0.0004 0.0001 0.0003 0.0001 0.0001 0.0002
Vacuole 0.0018 0.0006 0.0012 0.0019 0.0012 0.0014 0.0004 0 0.0003 0.0004 0.0003 0.0002 0.0003 0.0001 0.0004 0.0004 0.0001 0.0002
Vacuole Periphery 0.001 0.0001 0.0006 0.0008 0.0008 0.0003 0.0003 0 0.0003 0.0001 0.0001 0 0 0 0.0001 0.0001 0 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 75.7969 55.5392 115.3949 77.6974 90.2188 139.0911 61.2096 62.9161 102.0862 60.3801
Translational Efficiency 0.6766 0.7942 0.4294 1.5352 0.9935 0.3332 0.7472 0.9951 0.6126 0.8193

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1043 759 254 1371 1790 693 1430 1688 2833 1452 1684 3059

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 712.55 801.72 1471.83 1313.44 788.76 936.54 1252.08 1430.65 760.70 866.07 1285.23 1378.12
Standard Deviation 111.09 134.67 326.32 280.43 101.81 259.14 206.99 284.03 111.55 214.63 242.13 288.37
Intensity Change Log 2 — 0.170107 1.046548 0.882287 — 0.247754 0.666668 0.859012 — 0.211422 0.859457 0.870106

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000243 0.000231 0.002082 0.002859 0.000149 0.000736 0.000376 0.002538 0.000183 0.000472 0.000633 0.002682
Bud Neck 0.004908 0.009153 0.007516 0.003553 0.005337 0.008131 0.001848 0.002041 0.005179 0.008665 0.002703 0.002719
Bud Site 0.014010 0.016087 0.024920 0.031212 0.007251 0.026227 0.012631 0.021202 0.009739 0.020927 0.014484 0.025688
Cell Periphery 0.000216 0.000107 0.001447 0.000429 0.000122 0.000147 0.000172 0.000295 0.000156 0.000126 0.000364 0.000355
Cytoplasm 0.636012 0.634917 0.510376 0.619740 0.639914 0.609098 0.841166 0.729879 0.638478 0.622594 0.791272 0.680516
Cytoplasmic Foci 0.214946 0.139889 0.068543 0.054172 0.172538 0.194949 0.029283 0.042248 0.188151 0.166168 0.035205 0.047592
Eisosomes 0.000071 0.000054 0.000044 0.000022 0.000080 0.000069 0.000010 0.000023 0.000077 0.000061 0.000015 0.000022
Endoplasmic Reticulum 0.004112 0.000993 0.002412 0.000718 0.001192 0.001075 0.000242 0.000754 0.002267 0.001032 0.000570 0.000738
Endosome 0.010744 0.014505 0.013951 0.005117 0.009158 0.017090 0.001114 0.005349 0.009742 0.015739 0.003050 0.005245
Golgi 0.004040 0.000962 0.002689 0.006562 0.001688 0.004993 0.000656 0.005193 0.002554 0.002886 0.000963 0.005806
Lipid Particles 0.003905 0.002246 0.019530 0.006670 0.002984 0.002337 0.001366 0.004288 0.003323 0.002289 0.004106 0.005355
Mitochondria 0.002363 0.000518 0.000080 0.001576 0.002115 0.002979 0.000090 0.002068 0.002206 0.001693 0.000088 0.001848
Mitotic Spindle 0.000425 0.002236 0.002139 0.133317 0.001540 0.009892 0.006543 0.082447 0.001129 0.005890 0.005879 0.105246
None 0.002845 0.004286 0.003612 0.002344 0.002030 0.000839 0.003524 0.002415 0.002330 0.002641 0.003538 0.002383
Nuclear Periphery 0.000184 0.000230 0.000551 0.000222 0.000156 0.000107 0.000098 0.000137 0.000166 0.000172 0.000166 0.000175
Nuclear Periphery Foci 0.001757 0.002584 0.038885 0.007609 0.001036 0.001551 0.005621 0.004548 0.001301 0.002091 0.010638 0.005920
Nucleolus 0.000387 0.001243 0.000162 0.000218 0.000349 0.000904 0.000115 0.000133 0.000363 0.001081 0.000122 0.000171
Nucleus 0.044088 0.043841 0.049474 0.032628 0.069331 0.026152 0.044460 0.029827 0.060037 0.035399 0.045216 0.031082
Peroxisomes 0.001475 0.002139 0.006183 0.001949 0.001238 0.005028 0.000523 0.001951 0.001326 0.003518 0.001377 0.001950
Vacuole 0.050729 0.122702 0.243740 0.087472 0.080873 0.085884 0.050075 0.060577 0.069775 0.105129 0.079285 0.072631
Vacuole Periphery 0.002539 0.001076 0.001665 0.001611 0.000920 0.001813 0.000087 0.002087 0.001516 0.001428 0.000325 0.001874

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.03 -3.86 -3.88 -3.88 0.14 -2.62 -2.91 -3.26 -0.50 -1.56 -2.72 -4.26 -5.10 -3.25 -2.34
Bud Neck -2.31 -4.07 -0.03 2.41 5.00 -3.09 7.79 4.70 5.62 -5.08 -3.39 5.62 3.05 4.71 -4.07
Bud Site -0.76 -5.02 -8.37 -5.69 -1.32 -7.31 -4.10 -9.82 2.18 -4.70 -6.46 -4.30 -13.29 -2.17 -7.00
Cell Periphery 7.17 -5.98 -2.61 -6.78 5.49 -2.19 -4.43 -2.73 -1.45 -0.25 3.48 -6.08 -4.23 -6.01 3.19
Cytoplasm 0.64 9.06 11.19 9.25 -2.21 2.62 -18.61 1.75 -1.14 17.28 2.32 -13.00 9.14 5.14 19.77
Cytoplasmic Foci 9.22 19.80 18.09 7.66 -2.74 -2.74 31.08 21.28 16.44 -7.24 3.93 38.94 27.31 17.35 -10.07
Eisosomes 2.34 5.02 11.19 5.22 6.25 2.10 23.09 18.11 10.75 -1.53 3.51 23.85 21.52 10.66 -1.08
Endoplasmic Reticulum 5.34 3.17 6.47 4.30 7.21 0.37 6.17 5.57 2.34 0.14 4.39 7.18 8.19 3.93 3.68
Endosome -2.79 0.06 9.23 9.68 5.85 -5.04 17.39 11.36 9.41 -3.30 -5.96 15.86 14.71 13.45 -0.82
Golgi 8.41 3.56 3.35 -1.03 0.16 -3.12 3.96 0.73 3.27 -1.95 -0.53 6.77 2.65 2.26 -1.98
Lipid Particles 4.11 -6.00 -4.46 -6.95 4.46 1.96 3.99 -2.12 -3.15 -4.07 4.10 -2.26 -4.86 -7.10 -2.12
Mitochondria 4.42 5.52 4.24 0.45 -1.48 -0.68 2.76 2.05 2.37 -1.83 0.78 4.35 3.38 2.38 -2.37
Mitotic Spindle -1.69 -5.87 -17.38 -16.80 -17.00 -3.03 -3.87 -15.36 -12.64 -13.45 -3.31 -4.33 -23.07 -20.97 -20.40
None -1.11 0.69 0.60 1.54 -0.39 5.23 -2.43 -2.73 -10.78 0.38 -0.39 -1.20 -1.14 -0.13 0.39
Nuclear Periphery -1.09 -8.65 -9.05 -7.05 2.04 2.61 -1.27 -11.02 -12.42 -9.42 -0.33 -4.74 -13.90 -10.96 -9.22
Nuclear Periphery Foci -2.99 -10.57 -11.96 -9.97 7.78 -2.18 -11.17 -12.21 -9.87 0.67 -4.38 -14.08 -17.08 -13.62 3.87
Nucleolus -1.98 3.16 -0.83 1.74 -4.21 -0.97 10.52 -1.37 0.71 -3.58 -2.06 7.24 -1.71 1.65 -5.53
Nucleus -0.18 -2.33 3.61 3.62 4.49 12.84 6.43 12.86 -3.32 7.20 10.16 3.21 12.99 0.17 9.32
Peroxisomes -0.91 -0.50 0.15 1.73 0.53 -4.19 3.54 0.55 4.28 -2.46 -4.41 1.08 0.27 4.68 -0.99
Vacuole -12.05 -14.84 -20.30 -6.25 6.56 -1.13 -1.26 -11.47 -8.43 -9.52 -9.23 -10.46 -21.73 -9.40 -7.29
Vacuole Periphery 2.86 2.28 3.98 3.17 0.93 -1.38 3.22 1.17 2.07 -1.76 0.32 5.01 3.62 2.97 -1.44
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit 6 of the ubiquinol cytochrome-c reductase complex; the complex, also known as the cytochrome bc(1) complex or Complex III, is a component of the mitochondrial inner membrane electron transport chain; highly acidic protein; required for maturation of cytochrome c1; may be loosely associated with the complex since it is easily released into the intermembrane space
Localization
Cell Percentages cytoplasm (88%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Qcr6

Qcr6


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Qcr6-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available