Standard name
Human Ortholog
Description Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase; regulates filamentous growth along with Mig2p in response to glucose depletion; activated in stochastic pulses of nuclear localization, shuttling between cytosol and nucleus depending on external glucose levels and its phosphorylation state
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.07 0.09
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.06 0.06 0 0.07 0.05 0.06 0 0 0 0 0 0 0.15 0.18 0.31 0.23 0.2 0.15 0 0 0 0.08 0.12 0.16
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.06 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0.05 0.06
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.26 0.08 0.28 0.2 0.2 0.5 0.58 0.49 0.57 0.66 0.67 0.68 0 0 0 0.05 0 0.06 0 0 0 0 0 0
Nucleus 0.75 0.77 0.77 0.8 0.76 0.66 0.59 0.69 0.7 0.65 0.66 0.64 0.78 0.64 0.44 0.59 0.52 0.66 0.71 0.75 0.68 0.6 0.38 0.26
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.06 0 0 0 0 0 0.07 0 0.09 0.08 0.1 0.11 0 0 0 0 0 0 0.1 0.06 0.06 0.05 0.12 0.07
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0.08
Vac/Vac Membrane 0.11 0.15 0.08 0 0.09 0.11 0 0 0 0 0 0.05 0.06 0.16 0.27 0.2 0.26 0.18 0.05 0.05 0.12 0.13 0.11 0.15
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1
Bud 0 0 1 0 0 0 5 0 0 3 0 3 0 0 0 1 0 0 4 5 5 5 18 19
Bud Neck 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 1 6
Bud Site 0 1 0 0 1 3 4 5 8 18 4 6 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
Cytoplasm 8 11 4 3 8 14 13 16 8 14 6 13 23 45 65 69 27 13 4 4 3 8 31 33
Endoplasmic Reticulum 0 1 0 0 0 1 0 0 1 0 0 0 0 1 1 13 12 5 0 0 0 0 1 1
Endosome 0 2 0 0 0 0 0 0 1 0 0 0 0 7 7 11 8 2 4 5 1 2 12 13
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 1 2 1 0 0 0 2
Mitochondria 36 15 36 9 30 118 189 185 158 209 145 199 3 5 1 14 1 5 0 2 0 0 2 3
Nucleus 105 143 99 35 113 157 193 259 196 206 142 187 119 155 94 179 71 59 107 165 103 62 100 56
Nuclear Periphery 0 0 0 0 1 0 4 3 2 7 2 0 0 0 0 0 0 1 0 0 0 0 1 1
Nucleolus 8 8 2 0 4 1 22 16 25 24 21 32 2 5 4 3 2 0 14 14 9 4 32 15
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 1 1 0 3 0 0 0 1 0 1 0 0 3 4 3 4 26 17
Vac/Vac Membrane 16 27 10 1 13 25 10 12 5 5 9 14 9 38 57 60 36 16 7 11 18 13 30 32
Unique Cell Count 140 185 128 44 149 238 325 377 279 316 215 291 152 244 212 304 137 89 151 219 152 104 267 214
Labelled Cell Count 173 208 152 48 170 320 441 497 404 489 329 454 156 259 229 354 158 102 151 219 152 104 267 214


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.4 6.2 4.9 5.1 5.1 4.7 4.1 4.6 4.6 4.2 4.3 4.3 6.9 6.4 6.0 7.8 9.3 10.9 6.4 6.7 7.3
Std Deviation (1e-4) 0.9 1.1 0.9 1.3 1.1 1.2 1.0 1.0 1.1 1.2 1.0 1.1 1.4 1.3 1.2 1.9 2.1 2.2 1.6 1.8 1.8
Intensity Change (Log2) – – – 0.07 0.06 -0.07 -0.25 -0.09 -0.1 -0.22 -0.21 -0.19 0.49 0.37 0.3 0.67 0.92 1.15 0.38 0.45 0.57

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.9 1.2 0 0.6 0 0.6 0 0.6 3.4 4.2 6.1 5.0 4.2 3.1
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 3.4 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -1.0 -1.6 0 0 0 0 0 0 0 -6.3 -7.6 -7.9 -7.0 -6.4 -4.2
Nucleus 0.3 -0.3 -2.3 -3.6 -1.9 -1.5 -2.5 -2.2 -2.6 0.2 -2.7 -6.0 -3.7 -4.3 -1.8
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0.3 0.8 -2.2 -2.2 0 0 -1.4 -1.2 -0.6 2.1 4.3 3.1 4.0 2.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.1932 3.6727 3.3362 3.3325 2.8486 3.6339 3.2475 3.1808 3.0165 2.7372 2.3142 3.0541 3.8954 4.723 4.0837 4.024 3.5321 4.2377
Actin 0.0005 0.0001 0.0001 0.0002 0.0004 0 0.0156 0.0009 0.0238 0.0002 0.0007 0.0002 0.0739 0 0.0287 0.0025 0.0001 0.0006
Bud 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001 0.001 0.0003 0.0003 0.0001 0.0003 0.0001 0.0008 0 0.0006 0.0059 0.0001 0.0001
Bud Neck 0.0006 0.0003 0.0002 0.0002 0.0011 0.0018 0.0051 0.0011 0.0007 0.0004 0.001 0.0027 0.0009 0.0002 0.004 0.0026 0.0012 0.0032
Bud Periphery 0.0002 0 0 0 0.0001 0.0001 0.002 0.0002 0.0002 0 0.0002 0.0002 0.0014 0 0.0008 0.0128 0 0.0001
Bud Site 0.0006 0.0005 0.0004 0.0003 0.0004 0.0001 0.0033 0.0032 0.0092 0.0002 0.0002 0.0002 0.0083 0.0003 0.0022 0.0166 0.0006 0.0003
Cell Periphery 0.0001 0 0 0 0.0001 0 0.0007 0.0001 0.0001 0 0 0 0.0005 0 0.0002 0.0022 0 0
Cytoplasm 0.0289 0.0043 0.0179 0.0022 0.0104 0.0013 0.043 0.0486 0.0059 0.0651 0.0696 0.003 0.0479 0.0101 0.0059 0.1186 0.0112 0.0064
Cytoplasmic Foci 0.0047 0 0.0002 0 0.0004 0 0.0306 0.0174 0.0044 0.0003 0.0199 0.0018 0.0295 0.0002 0.0005 0.0039 0.0001 0.0004
Eisosomes 0 0 0 0 0 0 0.0004 0 0.0001 0 0 0 0.0007 0 0.0002 0.0003 0 0
Endoplasmic Reticulum 0.0088 0.0001 0.0002 0.0001 0.0029 0.0001 0.0058 0.0014 0.0003 0.0009 0.0021 0.0002 0.0122 0.0002 0.0015 0.0044 0.0005 0.0004
Endosome 0.021 0.0001 0.0002 0.0001 0.0028 0 0.0354 0.0036 0.0032 0.0005 0.0113 0.0059 0.058 0.0001 0.0033 0.0065 0.0007 0.0029
Golgi 0.0005 0 0 0 0.0001 0 0.0198 0.0007 0.0042 0 0.002 0.0046 0.0459 0 0.003 0.0017 0 0.0034
Lipid Particles 0.001 0 0 0 0.0004 0 0.0248 0.0001 0.0031 0 0.0006 0.0033 0.0913 0 0.0004 0.0031 0 0.0001
Mitochondria 0.0017 0.0002 0.0002 0.0003 0.0003 0.0001 0.0157 0.0007 0.0009 0.0004 0.0533 0.0009 0.1176 0.0001 0.0034 0.0124 0.0003 0.0171
None 0.0027 0.0002 0.0006 0.0002 0.0009 0 0.0113 0.0247 0.0048 0.0251 0.0072 0.0006 0.0036 0.0002 0.0012 0.0056 0.0006 0.001
Nuclear Periphery 0.0554 0.0046 0.0035 0.0036 0.0281 0.0009 0.0233 0.0127 0.004 0.0099 0.0138 0.0024 0.0177 0.0064 0.016 0.015 0.0109 0.0057
Nucleolus 0.0308 0.0093 0.0056 0.0032 0.0098 0.0183 0.0045 0.0144 0.0058 0.0023 0.007 0.0155 0.0018 0.0033 0.0037 0.013 0.0067 0.0115
Nucleus 0.7854 0.9636 0.9607 0.9813 0.9066 0.976 0.7161 0.8463 0.9028 0.8871 0.7769 0.9473 0.4536 0.9331 0.9136 0.7525 0.9586 0.9249
Peroxisomes 0.0001 0 0 0 0 0 0.0194 0.0006 0.0012 0 0.0012 0.0005 0.0222 0 0.0002 0.001 0 0.0001
Punctate Nuclear 0.0467 0.0163 0.0098 0.0079 0.0334 0.0007 0.0106 0.0193 0.0248 0.007 0.0306 0.01 0.0014 0.0453 0.0095 0.0044 0.0075 0.0212
Vacuole 0.007 0.0002 0.0002 0.0001 0.0013 0.0003 0.0082 0.0033 0.0003 0.0003 0.0016 0.0004 0.0058 0.0004 0.0006 0.0131 0.0006 0.0005
Vacuole Periphery 0.0029 0.0001 0.0001 0.0001 0.0003 0 0.0035 0.0005 0.0001 0.0001 0.0005 0.0001 0.0048 0.0001 0.0003 0.0019 0.0001 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 12.7456 16.9279 21.2575 34.1888 16.0531 16.0142 21.0656 18.4388 27.4831 25.3236
Translational Efficiency 1.7035 1.422 1.3478 1.2489 2.0343 1.6255 1.0857 1.7475 1.5596 1.5849

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
631 1206 872 2316 2061 1385 380 1791 2692 2591 1252 4107

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 726.38 843.42 1105.40 1167.50 780.77 843.12 1190.07 1142.50 768.02 843.26 1131.10 1156.60
Standard Deviation 94.70 128.14 149.75 159.10 98.41 124.02 147.57 161.40 100.24 125.96 154.09 160.58
Intensity Change Log 2 — 0.215527 0.605772 0.684626 — 0.110840 0.608077 0.549225 — 0.162244 0.606967 0.616070

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000234 0.000961 0.001256 0.000981 0.000140 0.000445 0.001637 0.001578 0.000162 0.000685 0.001372 0.001242
Bud Neck 0.002548 0.010517 0.020964 0.049818 0.004551 0.008669 0.014338 0.038524 0.004082 0.009529 0.018953 0.044893
Bud Site 0.000368 0.002426 0.003083 0.011632 0.000653 0.003161 0.002344 0.018451 0.000586 0.002819 0.002859 0.014605
Cell Periphery 0.000135 0.000129 0.000148 0.000156 0.000080 0.000096 0.000125 0.000242 0.000093 0.000111 0.000141 0.000193
Cytoplasm 0.019383 0.048580 0.010833 0.023002 0.084255 0.032548 0.004454 0.039036 0.069049 0.040010 0.008897 0.029994
Cytoplasmic Foci 0.001427 0.004832 0.000346 0.001332 0.005121 0.002972 0.000080 0.013194 0.004255 0.003838 0.000265 0.006505
Eisosomes 0.000025 0.000030 0.000034 0.000025 0.000015 0.000022 0.000042 0.000031 0.000017 0.000026 0.000037 0.000027
Endoplasmic Reticulum 0.002067 0.006103 0.004926 0.004393 0.002018 0.003069 0.006652 0.005385 0.002029 0.004481 0.005450 0.004825
Endosome 0.000315 0.002912 0.000907 0.002789 0.000622 0.002014 0.000301 0.014807 0.000550 0.002432 0.000723 0.008030
Golgi 0.000102 0.001421 0.000151 0.001993 0.000104 0.000844 0.000129 0.017161 0.000104 0.001112 0.000144 0.008607
Lipid Particles 0.000445 0.001992 0.000285 0.000179 0.000850 0.001421 0.000222 0.000814 0.000755 0.001686 0.000266 0.000456
Mitochondria 0.000532 0.002399 0.001544 0.006066 0.001600 0.003767 0.001655 0.008370 0.001350 0.003130 0.001578 0.007071
Mitotic Spindle 0.000066 0.004394 0.004049 0.054633 0.002338 0.008554 0.003415 0.141738 0.001806 0.006618 0.003856 0.092618
None 0.010768 0.010839 0.004488 0.005892 0.006809 0.008127 0.002633 0.005805 0.007737 0.009389 0.003925 0.005854
Nuclear Periphery 0.000495 0.001620 0.000700 0.005297 0.001724 0.001445 0.000694 0.007987 0.001436 0.001526 0.000698 0.006470
Nuclear Periphery Foci 0.000360 0.001536 0.000896 0.001565 0.000757 0.000848 0.000281 0.006184 0.000664 0.001168 0.000709 0.003579
Nucleolus 0.015688 0.015714 0.009655 0.005060 0.006225 0.015314 0.007738 0.005712 0.008443 0.015500 0.009073 0.005344
Nucleus 0.944049 0.876333 0.930065 0.808263 0.879619 0.901127 0.947977 0.632064 0.894722 0.889586 0.935501 0.731425
Peroxisomes 0.000273 0.001240 0.000365 0.000442 0.000430 0.001074 0.000392 0.001527 0.000393 0.001151 0.000373 0.000915
Vacuole 0.000588 0.005165 0.005093 0.012534 0.001926 0.003731 0.004724 0.031822 0.001612 0.004399 0.004981 0.020945
Vacuole Periphery 0.000131 0.000857 0.000210 0.003949 0.000162 0.000755 0.000168 0.009568 0.000155 0.000803 0.000197 0.006399

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.28 -16.06 -13.66 0.05 5.40 -3.34 -16.45 -18.38 -6.71 3.11 -6.35 -23.21 -23.68 -4.39 5.32
Bud Neck -8.74 -16.26 -25.31 -18.38 -8.52 -4.53 -10.76 -20.87 -16.69 -9.89 -8.47 -18.04 -31.95 -24.95 -11.22
Bud Site -6.36 -11.82 -10.94 -6.26 -4.53 -3.83 -9.71 -11.47 -6.38 -7.82 -5.90 -13.84 -15.59 -8.44 -8.47
Cell Periphery 0.13 0.18 0.32 0.71 0.46 -1.65 -4.29 -4.49 -3.03 -0.78 -1.49 -2.54 -3.05 -2.15 -0.28
Cytoplasm -6.18 3.82 1.09 9.11 -6.24 11.94 21.91 14.40 1.89 -12.60 8.29 21.03 15.85 8.47 -12.29
Cytoplasmic Foci -3.53 3.70 3.42 5.47 -0.74 2.88 8.38 3.60 0.83 -5.12 1.08 8.69 5.97 5.07 -4.97
Eisosomes -0.98 -2.28 -0.96 0.16 4.20 -4.14 -11.76 -15.27 -8.02 3.33 -4.59 -11.09 -9.45 -5.19 4.77
Endoplasmic Reticulum -11.91 -11.20 -12.08 3.98 2.27 -5.27 -10.43 -16.18 -11.01 2.34 -12.45 -15.31 -19.46 -3.65 2.57
Endosome -3.89 -2.31 -3.77 2.90 -0.57 -2.79 2.14 -5.64 -2.12 -6.13 -4.55 -0.63 -6.04 0.84 -5.04
Golgi -2.27 -2.72 -2.05 1.31 -1.55 -2.78 -3.30 -3.67 -2.83 -3.58 -3.32 -5.33 -4.10 -1.60 -3.86
Lipid Particles -2.39 2.02 3.22 2.78 2.07 -1.16 3.62 2.74 1.93 -1.89 -2.28 4.54 4.30 3.43 -0.96
Mitochondria -6.98 -13.75 -17.06 -5.83 -10.91 -2.94 -1.39 -7.96 -2.11 -9.34 -3.96 -2.15 -10.89 -4.03 -14.41
Mitotic Spindle -4.19 -3.92 -11.83 -8.95 -8.00 -2.87 -1.14 -14.11 -11.98 -12.02 -3.85 -2.88 -17.65 -14.60 -14.31
None 0.53 4.02 2.47 2.67 -7.19 -1.41 7.11 -0.67 1.02 -9.45 -1.34 6.91 1.40 2.79 -10.66
Nuclear Periphery -7.87 -3.81 -11.77 -7.40 -10.36 0.90 3.06 -6.35 -6.68 -8.15 -0.84 2.92 -10.24 -9.82 -13.09
Nuclear Periphery Foci -3.17 -1.15 -0.90 2.95 0.60 -0.70 1.13 -2.22 -1.54 -2.81 -2.91 0.21 -1.43 2.15 -1.28
Nucleolus -0.50 0.16 5.81 6.90 6.50 -6.59 -2.03 -1.99 4.83 0.71 -6.99 -4.51 1.41 8.38 5.74
Nucleus 9.17 4.27 13.54 2.80 10.79 -2.91 -7.63 11.82 13.60 17.46 1.42 -5.45 13.45 11.68 19.66
Peroxisomes -2.94 -2.27 1.86 3.21 3.96 -1.45 0.60 -0.05 1.44 -0.68 -2.65 0.10 1.12 3.12 1.62
Vacuole -6.51 -5.51 -11.53 -6.15 -4.52 -2.22 -3.49 -12.60 -10.93 -5.18 -5.05 -5.64 -16.25 -12.30 -7.54
Vacuole Periphery -4.06 -3.59 -3.24 -0.47 -2.87 -2.78 -0.93 -5.21 -3.26 -5.13 -4.57 -2.99 -6.00 -2.72 -5.72
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase; regulates filamentous growth along with Mig2p in response to glucose depletion; activated in stochastic pulses of nuclear localization, shuttling between cytosol and nucleus depending on external glucose levels and its phosphorylation state
Localization
Cell Percentages nucleus (93%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Mig1

Mig1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mig1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available