Standard name
Human Ortholog
Description Subunit (60 kDa) of TFIID and SAGA complexes; involved in transcription initiation of RNA polymerase II and in chromatin modification, similar to histone H4; relocalizes to the cytosol in response to hypoxia
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0.06 0 0.06 0.06 0.1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.09 0.06 0.08 0.08 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0.07 0 0.08 0.12 0.13 0.14 0.12 0.13 0.17 0.2 0 0 0 0.05 0 0 0 0 0 0 0 0
Nucleus 0.9 0.86 0.88 0.88 0.85 0.77 0.75 0.74 0.74 0.71 0.53 0.58 0.89 0.8 0.75 0.82 0.8 0.75 0.83 0.8 0.81 0.74 0.67 0.64
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.45 0.38 0.39 0.28 0.29 0.39 0.48 0.5 0.47 0.59 0.72 0.67 0.3 0.38 0.31 0.18 0.17 0.25 0.13 0.13 0.13 0.19 0.24 0.24
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 3 0 0 3 2 1 0 1 3
Bud Neck 0 1 0 1 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 1 0 0 1 1 4 1 9 3 7 4 11 2 3 3 2 0 3 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 1 0 0 0 0 0 0
Cytoplasm 10 1 2 0 1 3 2 4 3 1 1 1 12 30 33 23 27 20 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 6 4 0 0 0 0 0 1
Endosome 0 1 0 0 0 0 0 0 0 0 0 0 1 2 1 2 3 1 2 0 0 3 1 4
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1
Mitochondria 5 4 8 3 6 14 18 22 12 15 11 22 0 2 1 17 1 10 0 0 0 1 0 3
Nucleus 393 167 100 69 62 90 107 116 75 82 34 64 318 339 276 299 262 190 362 167 94 176 206 249
Nuclear Periphery 0 0 0 0 0 0 0 3 2 2 1 0 2 1 1 6 1 2 0 1 0 0 0 2
Nucleolus 198 73 44 22 21 46 69 78 47 68 46 74 107 161 113 67 57 64 58 27 15 45 74 92
Peroxisomes 0 1 0 0 0 0 0 0 0 0 0 0 0 4 5 2 0 0 0 0 0 0 0 0
SpindlePole 1 0 0 0 0 0 0 1 0 0 0 1 4 9 8 4 1 3 1 0 0 1 1 5
Vac/Vac Membrane 1 0 0 0 0 1 0 0 0 1 1 0 0 2 6 1 3 6 6 8 2 7 16 24
Unique Cell Count 436 194 114 78 73 117 143 156 101 115 64 111 357 425 369 364 329 253 438 211 117 238 308 392
Labelled Cell Count 609 248 154 96 91 158 197 234 143 177 98 173 447 553 447 432 361 304 438 211 117 238 308 392


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 10.4 12.0 8.4 8.6 9.0 7.5 7.2 6.3 7.4 7.0 6.5 7.0 11.2 11.1 10.7 10.8 14.5 12.2 8.5 8.9 9.3
Std Deviation (1e-4) 3.1 2.9 2.2 2.4 4.0 2.4 2.6 2.0 2.2 2.3 2.1 2.0 2.9 3.2 3.4 4.2 4.5 4.9 2.2 1.9 1.9
Intensity Change (Log2) – – – 0.02 0.09 -0.17 -0.22 -0.43 -0.2 -0.28 -0.38 -0.27 0.4 0.4 0.34 0.35 0.78 0.53 0.01 0.08 0.15


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 3.4 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 2.1 2.6 1.9 2.4 2.3
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.3 1.3 1.5 1.8 1.2 1.5 2.1 2.8 0 0 0 -1.0 0 -1.3
Nucleus 0.2 -0.5 -2.1 -2.6 -2.7 -2.5 -3.1 -5.1 -5.1 0.4 -1.9 -2.9 -1.4 -1.9 -2.7
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus -1.5 -1.4 0.1 1.5 1.9 1.2 3.1 4.3 4.2 -1.7 -0.1 -1.6 -4.5 -4.7 -2.6
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.0303 0.0113 0.0001 0 0.0002 0 0.0038 0 0.0223 0 0.0001 0 0.0583 0.0002 0.0434 0.0004 0.0338 0.0002
Bud 0.0012 0.0085 0.0001 0 0.0002 0.0001 0.0005 0 0.0002 0 0.0003 0 0.0025 0.0001 0.0001 0.0001 0.0013 0.0001
Bud Neck 0.0007 0.0028 0.0001 0.0001 0.0009 0.0005 0.0003 0 0.0002 0 0.0003 0.0003 0.0077 0 0.0021 0.0001 0.0003 0.0003
Bud Periphery 0.0013 0.0062 0.0001 0.0001 0.001 0.0002 0.0006 0 0.0004 0 0.0012 0 0.0041 0.0003 0.0002 0.0001 0.0039 0.0001
Bud Site 0.0103 0.0732 0.0002 0 0.0002 0.0001 0.0011 0 0.0004 0 0.0005 0 0.0455 0.0002 0.0018 0.0003 0.0007 0.0001
Cell Periphery 0.0004 0.0017 0.0001 0.0001 0.0002 0.0001 0.0002 0 0.0001 0 0.0002 0 0.0019 0.0001 0.0003 0 0.0002 0.0001
Cytoplasm 0.0074 0.0147 0.0004 0 0.0001 0 0.0039 0 0.0009 0 0 0.0011 0.0059 0.0001 0.0015 0.0004 0.0014 0.0002
Cytoplasmic Foci 0.1389 0.0178 0.0046 0 0 0 0.01 0 0.0034 0 0.0001 0.0022 0.0551 0.0003 0.0041 0.0068 0.0035 0.0005
Eisosomes 0.0008 0.0002 0 0 0 0 0.0001 0 0.0001 0 0 0 0.0006 0 0.0003 0 0.0003 0
Endoplasmic Reticulum 0.0057 0.0068 0.0001 0 0.0001 0 0.0015 0 0.0079 0 0 0.0001 0.0021 0 0.0006 0.0001 0.0063 0.0006
Endosome 0.0892 0.0064 0.0004 0.0001 0.0002 0 0.0109 0 0.0068 0 0.0001 0.0004 0.0275 0.0001 0.002 0.0037 0.05 0.0007
Golgi 0.0334 0.0021 0.0002 0 0 0 0.002 0 0.005 0 0 0 0.0147 0.0001 0.0021 0.001 0.0208 0.0001
Lipid Particles 0.2836 0.0126 0.0042 0.0001 0.0001 0 0.0083 0 0.0088 0 0.0002 0.0002 0.0427 0.0009 0.0018 0.0072 0.0111 0.0015
Mitochondria 0.0087 0.0028 0.0024 0.0003 0.0035 0.0003 0.0017 0.0001 0.0063 0.0001 0.0024 0.0001 0.0143 0.0212 0.0003 0.0007 0.0247 0.0008
None 0.0278 0.0024 0.0007 0 0.0002 0 0.004 0 0.0005 0 0.0001 0.0006 0.0109 0.0001 0.0008 0.0017 0.0022 0.0002
Nuclear Periphery 0.046 0.0137 0.007 0.0008 0.0028 0.0002 0.021 0.0001 0.0124 0.0001 0.0008 0.0005 0.0134 0.0005 0.0011 0.0015 0.0657 0.005
Nucleolus 0.014 0.0929 0.0779 0.1492 0.2428 0.2151 0.0777 0.0454 0.0366 0.0264 0.2091 0.1725 0.1264 0.04 0.0314 0.06 0.1614 0.1535
Nucleus 0.0089 0.6922 0.8703 0.8468 0.7448 0.7826 0.8013 0.9541 0.8663 0.9732 0.783 0.818 0.3657 0.9256 0.8923 0.8591 0.5932 0.8333
Peroxisomes 0.0471 0.0015 0.0003 0 0.0001 0 0.0065 0 0.002 0 0.0001 0 0.0284 0.0004 0.0029 0.0023 0.0016 0.0001
Punctate Nuclear 0.237 0.0198 0.0291 0.0003 0.0007 0.0002 0.0415 0.0001 0.0159 0.0002 0.0005 0.004 0.1521 0.0072 0.0108 0.0537 0.0106 0.0018
Vacuole 0.0034 0.0086 0.0004 0.0009 0.0009 0.0004 0.0019 0 0.0008 0 0.0006 0.0001 0.011 0.0007 0.0002 0.0003 0.0022 0.0003
Vacuole Periphery 0.0038 0.0019 0.0012 0.001 0.0011 0.0002 0.0012 0 0.0028 0 0.0003 0 0.0093 0.002 0.0001 0.0002 0.0048 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 31.658 31.1621 24.5394 30.7108 37.8176 29.8629 34.8838 32.9836 28.3177 37.7845
Translational Efficiency 1.1525 1.2031 1.1515 0.8233 0.7143 1.1492 1.014 0.824 0.945 0.9169

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2046 1605 262 1998 757 1789 306 106 2803 3394 568 2104

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 920.32 1188.77 1401.82 1408.82 1149.98 1135.11 1501.53 1442.71 982.34 1160.49 1455.54 1410.53
Standard Deviation 178.59 282.08 251.34 268.40 235.63 229.00 231.36 345.42 220.62 256.88 245.86 272.90
Intensity Change Log 2 — 0.369262 0.607094 0.614280 — -0.018777 0.384825 0.327173 — 0.166696 0.487879 0.461896

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000598 0.000563 0.001195 0.000723 0.000388 0.000566 0.000860 0.001111 0.000541 0.000565 0.001014 0.000743
Bud Neck 0.008539 0.004930 0.011416 0.019483 0.006140 0.005867 0.012903 0.011963 0.007891 0.005424 0.012217 0.019104
Bud Site 0.001342 0.000737 0.001339 0.001936 0.000500 0.000726 0.000923 0.003735 0.001115 0.000732 0.001115 0.002026
Cell Periphery 0.000120 0.000054 0.000032 0.000102 0.000042 0.000073 0.000020 0.000076 0.000099 0.000064 0.000025 0.000100
Cytoplasm 0.000915 0.001610 0.000042 0.000227 0.000022 0.000092 0.000028 0.000683 0.000674 0.000810 0.000035 0.000250
Cytoplasmic Foci 0.000163 0.001310 0.000122 0.000215 0.000036 0.000274 0.000070 0.010260 0.000129 0.000764 0.000094 0.000721
Eisosomes 0.000068 0.000108 0.000139 0.000061 0.000165 0.000103 0.000106 0.000077 0.000094 0.000105 0.000121 0.000061
Endoplasmic Reticulum 0.001859 0.000725 0.000914 0.000785 0.000998 0.000949 0.000546 0.000973 0.001626 0.000843 0.000716 0.000794
Endosome 0.000187 0.000074 0.000027 0.000391 0.000029 0.000374 0.000013 0.012214 0.000144 0.000232 0.000020 0.000987
Golgi 0.000131 0.000056 0.000127 0.000442 0.000024 0.000220 0.000072 0.006290 0.000102 0.000142 0.000097 0.000737
Lipid Particles 0.000152 0.000034 0.000025 0.000030 0.000004 0.000228 0.000012 0.000792 0.000112 0.000136 0.000018 0.000069
Mitochondria 0.000998 0.001148 0.002198 0.002479 0.000679 0.001020 0.001908 0.014539 0.000912 0.001081 0.002042 0.003087
Mitotic Spindle 0.002728 0.001454 0.000343 0.005556 0.000491 0.002544 0.003609 0.007939 0.002124 0.002028 0.002103 0.005676
None 0.006611 0.001768 0.000729 0.001136 0.000439 0.000573 0.000574 0.001574 0.004944 0.001139 0.000646 0.001158
Nuclear Periphery 0.000210 0.000109 0.000067 0.000526 0.000032 0.000144 0.000051 0.000392 0.000162 0.000128 0.000058 0.000519
Nuclear Periphery Foci 0.000355 0.000378 0.000018 0.000155 0.000014 0.000621 0.000008 0.000242 0.000263 0.000506 0.000013 0.000159
Nucleolus 0.096173 0.084512 0.098202 0.029769 0.059436 0.076941 0.069544 0.055198 0.086252 0.080521 0.082763 0.031050
Nucleus 0.877583* 0.897751* 0.873464* 0.933333* 0.929212* 0.905917* 0.904161* 0.848575* 0.891526* 0.902055* 0.890001* 0.929063*
Peroxisomes 0.000941 0.002130 0.008965 0.001041 0.000866 0.001833 0.004162 0.004174 0.000921 0.001974 0.006378 0.001199
Vacuole 0.000144 0.000269 0.000423 0.000888 0.000220 0.000444 0.000278 0.011544 0.000165 0.000361 0.000345 0.001425
Vacuole Periphery 0.000183 0.000279 0.000212 0.000721 0.000264 0.000489 0.000153 0.007648 0.000205 0.000390 0.000180 0.001070

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.12 -8.85 -4.38 -5.26 6.68 -4.08 -10.23 -4.73 -4.09 -2.96 -0.76 -11.46 -7.38 -6.20 5.14
Bud Neck 7.27 -4.28 -9.88 -12.93 -5.97 0.30 -6.65 -5.38 -5.67 -0.95 5.87 -7.25 -10.81 -13.03 -5.58
Bud Site 1.23 -0.81 -1.73 -3.71 -1.49 -1.51 -4.51 -2.89 -2.75 -2.53 1.12 -0.90 -2.95 -4.71 -2.99
Cell Periphery 4.17 5.99 0.92 -2.72 -4.09 -1.39 2.34 -2.68 -0.75 -3.63 2.11 6.72 -0.15 -1.90 -4.83
Cytoplasm -1.14 4.70 3.44 1.94 -5.92 -2.45 -1.05 -2.37 -2.19 -1.31 -0.65 1.91 2.52 1.58 -0.46
Cytoplasmic Foci -1.93 0.67 -0.81 1.81 -1.41 -2.14 -1.56 -1.87 -1.79 -1.86 -2.15 0.73 -2.21 0.89 -2.43
Eisosomes -6.23 -8.77 1.89 7.69 9.80 4.18 3.68 4.56 1.18 1.91 -1.86 -4.93 6.50 9.42 11.96
Endoplasmic Reticulum 12.28 4.34 12.02 -1.64 2.28 0.22 5.87 -2.23 -2.23 -2.98 8.22 8.59 9.71 -0.61 -0.55
Endosome 2.83 7.23 -1.53 -2.45 -2.88 -2.59 1.30 -1.75 -1.66 -1.76 -1.21 7.76 -2.42 -1.92 -2.94
Golgi 3.30 -1.04 -1.15 -1.49 -1.04 -2.27 -6.77 -1.53 -1.44 -1.50 -0.83 -1.14 -1.85 -1.66 -1.77
Lipid Particles 1.64 1.60 1.71 0.17 0.76 -2.28 -4.00 -2.03 -1.13 -1.99 -0.45 1.67 0.97 1.47 -2.07
Mitochondria -0.81 -8.95 -8.71 -6.58 -1.48 -2.30 -5.86 -1.89 -1.81 -1.56 -1.46 -8.75 -7.16 -6.43 -2.41
Mitotic Spindle 1.53 2.42 -1.71 -2.83 -3.47 -2.55 -1.58 -2.42 -2.16 -1.44 0.33 -0.87 -2.89 -3.08 -0.68
None 4.35 6.08 5.55 0.85 -2.19 -1.18 -1.78 -3.50 -3.27 -3.13 5.06 6.02 5.08 -0.44 -3.05
Nuclear Periphery 2.56 4.52 -2.80 -3.48 -3.67 -3.16 -2.77 -4.22 -2.99 -3.62 1.19 3.67 -3.31 -3.53 -3.87
Nuclear Periphery Foci -0.01 3.80 2.22 0.80 -2.70 -2.53 -0.24 -1.77 -0.20 -1.76 -1.23 3.85 1.18 1.76 -3.37
Nucleolus 2.86 -0.19 18.55 14.13 8.00 -3.74 -1.70 -1.25 0.26 -0.16 1.97 0.46 17.23 16.48 9.19
Nucleus -4.06 0.75 -10.67 -6.04 -6.28 4.42 3.86 4.21 3.28 2.72 -2.90 1.18 -7.15 -4.84 -5.76
Peroxisomes -6.62 -6.90 -0.37 3.71 6.71 -2.98 -6.23 -2.83 -2.31 -0.96 -5.97 -8.95 -1.46 2.22 7.84
Vacuole -2.87 -2.12 -3.37 -2.77 -0.13 -2.02 -1.53 -2.43 -2.37 -2.36 -3.42 -2.74 -4.02 -3.31 -2.08
Vacuole Periphery -2.83 -3.36 -2.91 -2.32 -2.65 -1.83 1.98 -1.30 -1.23 -1.33 -2.89 0.56 -2.92 -2.04 -2.96
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit (60 kDa) of TFIID and SAGA complexes; involved in transcription initiation of RNA polymerase II and in chromatin modification, similar to histone H4; relocalizes to the cytosol in response to hypoxia
Localization
Cell Percentages nucleus (97%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-2

Taf6

Taf6


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Taf6-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available