Standard name
Human Ortholog
Description Protein that interacts with Rab GTPases; localized to late Golgi vesicles; computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.86 0.93 1.0 0.96 0.98 0.95 0.88 0.89 0.75 0.81 0.67 0.69 1.0 0.99 0.99 0.91 0.91 0.89 0.49 0.71 0.72 0.78 0.75 0.73
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.05 0 0.13 0 0.05 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.15 0 0.06 0 0 0.1 0.18 0.12 0.37 0.23 0.52 0.32 0 0 0 0 0 0 0.23 0.11 0.12 0.12 0.09 0.1
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.06 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 0 0 0 0 0 0 1 1 0 1 3 0 0 0 7 6 7 7 1 0 1 4 7
Bud 2 0 0 1 0 1 9 8 7 5 12 9 0 1 0 1 5 5 0 0 0 0 6 2
Bud Neck 0 0 0 2 3 1 3 13 8 10 1 3 3 1 4 4 2 1 2 2 0 0 2 6
Bud Site 0 0 0 0 0 0 0 1 1 1 1 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 1 3 4 1 1 1 1 1 0 1 3 3 10 7 10 0 0 0 2 6 7
Cytoplasm 179 102 16 160 261 238 382 353 196 311 215 218 266 370 463 277 271 227 117 86 36 150 251 307
Endoplasmic Reticulum 8 3 0 1 2 0 0 0 1 1 4 11 1 0 1 18 16 10 31 3 2 2 5 7
Endosome 0 1 0 0 1 0 2 1 1 5 1 0 0 1 0 6 8 10 6 2 0 1 4 7
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 4 0 1 0 0 1 1
Mitochondria 32 3 1 4 0 25 78 49 96 89 169 101 1 1 2 4 5 5 53 13 5 23 29 40
Nucleus 0 0 0 2 2 1 1 2 1 0 2 1 0 0 0 0 2 0 0 0 0 0 1 0
Nuclear Periphery 0 1 0 0 0 0 2 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 1 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 1 2 4 7 2 7 4 3 0 0 0 1 2 2 1 0 0 1 3 6
Vac/Vac Membrane 2 1 0 3 1 4 2 2 3 8 3 5 0 1 3 6 8 6 11 7 2 3 7 13
Unique Cell Count 208 110 16 167 266 251 436 397 261 386 323 316 267 373 468 306 298 255 238 122 51 194 335 420
Labelled Cell Count 224 111 17 175 274 277 486 438 318 440 414 355 272 378 476 336 334 287 238 122 51 194 335 420


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.5 4.4 3.9 4.6 5.0 4.3 3.9 4.2 3.8 3.8 3.5 3.7 5.2 5.2 5.1 5.9 6.6 6.6 4.5 5.0 5.1
Std Deviation (1e-4) 0.4 0.7 0.6 1.3 1.3 1.3 1.2 0.9 1.6 1.1 1.0 0.7 1.2 0.9 1.4 1.0 1.6 1.8 0.7 1.6 1.4
Intensity Change (Log2) – – – 0.21 0.34 0.13 -0.01 0.08 -0.06 -0.05 -0.19 -0.1 0.39 0.4 0.38 0.59 0.73 0.74 0.18 0.33 0.38

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.767 1.6526 1.5782 -0.8178 0.1373 0.0883 -0.4169 0.1092 -0.1568 -0.3699 -0.2963 -0.1442 -1.1532 -1.0282 -1.0649 -1.0211 -0.705 -1.1292
Actin 0.0198 0.0018 0.0134 0.0023 0.0256 0.0035 0.0167 0.001 0.0047 0.0066 0.0178 0.003 0.0232 0.001 0.0127 0.0042 0.0476 0.004
Bud 0.0013 0.0035 0.0057 0.0002 0.0038 0.001 0.0004 0.0025 0.0011 0.0002 0.0004 0.0002 0.0014 0.0074 0.0008 0.0003 0.0007 0.0015
Bud Neck 0.0012 0.0003 0.0007 0.0002 0.0011 0.0015 0.0074 0.0007 0.0018 0.0004 0.0009 0.0005 0.0018 0.0042 0.0005 0.0002 0.0005 0.0023
Bud Periphery 0.0008 0.0036 0.0083 0.0003 0.0069 0.0008 0.0007 0.0011 0.002 0.0003 0.0006 0.0003 0.0024 0.0039 0.0022 0.0004 0.0007 0.0011
Bud Site 0.0084 0.0192 0.0113 0.0002 0.0241 0.0043 0.0099 0.0136 0.012 0.0012 0.0014 0.0001 0.0083 0.0203 0.0053 0.0006 0.0019 0.0004
Cell Periphery 0.0007 0.0006 0.0005 0.0001 0.0005 0.0001 0.0005 0.0002 0.0003 0.0002 0.0001 0.0001 0.0007 0.0004 0.0004 0.0001 0.0001 0.0001
Cytoplasm 0.0985 0.1239 0.1125 0.1978 0.0604 0.1747 0.1072 0.1381 0.1539 0.0847 0.1398 0.2176 0.1534 0.2697 0.2422 0.1655 0.0882 0.3255
Cytoplasmic Foci 0.0345 0.0132 0.0273 0.0161 0.0296 0.0285 0.0296 0.0074 0.0202 0.0265 0.0619 0.008 0.0213 0.0135 0.0253 0.0206 0.0877 0.0274
Eisosomes 0.0004 0.0004 0.0004 0.0001 0.0005 0.0002 0.0003 0.0001 0.0002 0.0002 0.0011 0.0001 0.0004 0.0004 0.0005 0.0002 0.0001 0.0001
Endoplasmic Reticulum 0.0075 0.0038 0.0049 0.0045 0.0041 0.0058 0.0074 0.0039 0.0044 0.0012 0.0018 0.0054 0.0097 0.011 0.0115 0.0051 0.0009 0.0125
Endosome 0.0494 0.0059 0.0204 0.0173 0.1251 0.01 0.0159 0.0026 0.0173 0.0279 0.0124 0.005 0.0187 0.007 0.0221 0.0199 0.0322 0.0083
Golgi 0.0098 0.0004 0.0096 0.0077 0.0377 0.0014 0.0048 0.0002 0.0013 0.0087 0.01 0.0012 0.0078 0.0005 0.0079 0.0013 0.0247 0.0056
Lipid Particles 0.0237 0.002 0.0226 0.0074 0.0513 0.0036 0.0107 0.0007 0.006 0.0647 0.023 0.0052 0.0121 0.0017 0.01 0.0037 0.0596 0.0078
Mitochondria 0.0227 0.023 0.0332 0.0331 0.0279 0.0079 0.0039 0.0007 0.0014 0.0063 0.0055 0.0009 0.0199 0.0009 0.023 0.0013 0.0044 0.0147
None 0.647 0.7859 0.6999 0.7022 0.5368 0.7302 0.7315 0.812 0.7519 0.7346 0.6642 0.7417 0.6922 0.6479 0.611 0.7543 0.5758 0.5703
Nuclear Periphery 0.0182 0.0027 0.0035 0.0018 0.0236 0.0068 0.0125 0.0015 0.0022 0.002 0.0102 0.0016 0.0045 0.0033 0.0048 0.0083 0.0007 0.0028
Nucleolus 0.0047 0.0009 0.0009 0.0002 0.0012 0.001 0.0038 0.0007 0.0012 0.0008 0.0029 0.0002 0.0009 0.0002 0.0007 0.0007 0.0001 0.0003
Nucleus 0.0083 0.0034 0.0017 0.0012 0.004 0.002 0.0048 0.0043 0.0025 0.0016 0.0033 0.0016 0.0019 0.0021 0.0021 0.003 0.0002 0.0019
Peroxisomes 0.0177 0.0008 0.0166 0.0036 0.017 0.0086 0.0139 0.0003 0.0052 0.0217 0.024 0.004 0.0105 0.0006 0.008 0.001 0.0664 0.0094
Punctate Nuclear 0.0079 0.0017 0.0027 0.0012 0.0061 0.0063 0.0139 0.0072 0.0072 0.0045 0.0172 0.0024 0.0043 0.0011 0.004 0.0045 0.0064 0.0022
Vacuole 0.0135 0.002 0.0028 0.0016 0.0082 0.0012 0.0024 0.001 0.0028 0.004 0.0005 0.0009 0.0036 0.0025 0.004 0.0035 0.0008 0.0012
Vacuole Periphery 0.0042 0.001 0.0011 0.0007 0.0045 0.0004 0.0015 0.0001 0.0005 0.0018 0.0008 0.0002 0.0009 0.0004 0.0011 0.0012 0.0004 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 31.34 31.7163 29.8108 41.7562 34.5003 34.2776 45.4301 48.3381 50.2759 44.0126
Translational Efficiency 1.6355 1.4587 1.8596 1.5993 1.4211 1.9144 1.3115 1.2272 1.4937 1.2159

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
220 592 2152 1217 1591 1608 101 1404 1811 2200 2253 2621

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 655.39 767.93 882.31 1002.55 654.45 716.46 1062.37 1072.25 654.56 730.31 890.38 1039.89
Standard Deviation 70.09 89.70 108.05 157.67 75.10 82.91 103.61 144.70 74.51 87.81 114.11 154.81
Intensity Change Log 2 — 0.228621 0.428932 0.613249 — 0.130603 0.698931 0.712286 — 0.180480 0.570142 0.663582

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000241 0.000865 0.000671 0.007181 0.000109 0.000286 0.002883 0.004223 0.000125 0.000442 0.000770 0.005597
Bud Neck 0.021088 0.030082 0.007527 0.007798 0.012373 0.028059 0.003925 0.008472 0.013432 0.028603 0.007366 0.008159
Bud Site 0.003630 0.017204 0.014371 0.025600 0.002204 0.010179 0.006565 0.024455 0.002377 0.012069 0.014021 0.024986
Cell Periphery 0.000269 0.000300 0.000307 0.002628 0.000215 0.000211 0.000781 0.001291 0.000221 0.000235 0.000328 0.001912
Cytoplasm 0.344002 0.299032 0.479423 0.210173 0.460069 0.372457 0.225972 0.187032 0.445969 0.352699 0.468061 0.197777
Cytoplasmic Foci 0.393467 0.353841 0.040978 0.063361 0.263443 0.279379 0.064432 0.058949 0.279238 0.299416 0.042030 0.060998
Eisosomes 0.000496 0.000330 0.000090 0.000830 0.000362 0.000265 0.000289 0.000664 0.000378 0.000282 0.000099 0.000741
Endoplasmic Reticulum 0.002086 0.005586 0.040512 0.357324 0.003236 0.003326 0.090060 0.339024 0.003096 0.003934 0.042733 0.347521
Endosome 0.027236 0.045322 0.006936 0.027572 0.012306 0.033110 0.020866 0.026768 0.014120 0.036397 0.007561 0.027141
Golgi 0.003130 0.014351 0.000223 0.008232 0.004387 0.006917 0.000494 0.006638 0.004234 0.008917 0.000235 0.007378
Lipid Particles 0.023200 0.027143 0.009709 0.054409 0.020235 0.019504 0.027511 0.065921 0.020595 0.021560 0.010507 0.060576
Mitochondria 0.004655 0.013170 0.001276 0.002019 0.005461 0.008089 0.000254 0.002277 0.005363 0.009456 0.001230 0.002157
Mitotic Spindle 0.000090 0.002584 0.003060 0.009903 0.000124 0.004553 0.000475 0.014530 0.000120 0.004023 0.002944 0.012382
None 0.000793 0.000908 0.001523 0.000699 0.003215 0.002155 0.000623 0.000629 0.002921 0.001820 0.001482 0.000661
Nuclear Periphery 0.000809 0.000720 0.009490 0.003703 0.000637 0.000839 0.011549 0.004870 0.000658 0.000807 0.009582 0.004328
Nuclear Periphery Foci 0.000994 0.001704 0.018118 0.031566 0.000426 0.000607 0.091374 0.044969 0.000495 0.000902 0.021402 0.038746
Nucleolus 0.001590 0.001111 0.000589 0.000203 0.000991 0.001963 0.000447 0.000244 0.001064 0.001734 0.000583 0.000225
Nucleus 0.097091 0.068191 0.268137 0.029064 0.156908 0.115963 0.136605 0.028586 0.149642 0.103108 0.262241 0.028808
Peroxisomes 0.013173 0.016541 0.001046 0.003142 0.004194 0.009757 0.001088 0.002039 0.005285 0.011582 0.001048 0.002551
Vacuole 0.060841 0.097281 0.095723 0.152391 0.048146 0.099273 0.313543 0.175848 0.049688 0.098737 0.105487 0.164956
Vacuole Periphery 0.001119 0.003733 0.000290 0.002201 0.000959 0.003108 0.000264 0.002571 0.000978 0.003276 0.000289 0.002399

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.43 -2.34 -6.13 -5.51 -5.68 -3.51 -2.08 -7.83 -7.46 -1.29 -5.25 -3.57 -9.20 -8.62 -7.78
Bud Neck -1.78 3.16 3.11 7.08 -0.16 -8.17 7.19 3.24 10.67 -4.92 -8.64 5.11 4.74 12.99 -0.95
Bud Site -5.46 -5.51 -10.19 -2.85 -4.59 -5.64 -4.19 -9.88 -5.46 -6.45 -7.87 -6.74 -14.59 -6.78 -5.26
Cell Periphery -0.76 -1.12 -6.51 -6.44 -6.43 0.27 -5.14 -9.34 -9.36 -3.12 -0.81 -6.29 -9.34 -9.26 -8.73
Cytoplasm 2.42 -7.22 7.49 7.12 27.90 9.99 10.74 31.59 20.31 1.52 11.94 -0.84 33.66 21.16 34.41
Cytoplasmic Foci 2.28 22.65 20.96 31.43 -6.45 -2.18 24.07 35.34 36.92 0.36 -2.97 45.17 40.43 47.31 -7.74
Eisosomes 2.41 5.98 -1.23 -2.04 -3.10 3.14 1.84 -2.57 -3.54 -3.25 3.57 12.24 -2.71 -3.55 -5.13
Endoplasmic Reticulum -3.74 -15.63 -31.66 -31.27 -27.51 -0.09 -5.76 -32.17 -32.13 -14.60 -1.17 -16.17 -45.02 -44.87 -37.83
Endosome -3.57 5.34 0.16 5.21 -12.36 -10.84 -5.04 -9.63 3.35 -3.13 -12.65 6.89 -9.57 5.47 -18.29
Golgi -5.65 4.75 -4.47 3.25 -9.26 -2.87 8.76 -2.22 0.95 -9.58 -5.48 10.20 -4.03 2.39 -13.56
Lipid Particles -1.09 4.71 -7.65 -7.35 -14.91 0.49 -1.47 -13.15 -13.24 -9.39 -0.61 8.90 -16.22 -15.69 -22.00
Mitochondria -2.51 1.29 1.03 5.12 -1.29 -2.00 5.07 2.82 6.01 -3.04 -3.21 4.22 3.26 8.24 -1.78
Mitotic Spindle -2.13 -4.34 -5.19 -3.47 -3.55 -3.47 -3.19 -6.50 -4.07 -6.27 -3.97 -4.33 -8.31 -4.99 -5.99
None -0.53 -2.61 0.48 1.12 3.18 1.32 3.52 3.57 3.93 0.31 1.62 2.28 3.60 4.16 3.56
Nuclear Periphery 0.45 -10.86 -4.09 -4.30 5.62 -1.87 -5.72 -6.66 -6.30 3.06 -1.69 -11.77 -7.81 -7.46 6.00
Nuclear Periphery Foci -2.30 -15.01 -15.18 -14.77 -5.92 -2.50 -8.25 -17.83 -17.75 3.55 -4.50 -17.14 -23.41 -23.13 -8.82
Nucleolus 0.80 1.71 2.53 5.63 4.19 -4.27 4.29 6.27 8.60 3.20 -3.50 2.82 6.84 9.94 4.06
Nucleus 3.16 -18.47 8.20 8.12 46.35 7.76 1.35 30.57 21.14 6.93 10.14 -19.29 32.20 22.65 48.03
Peroxisomes -1.17 4.84 3.88 7.59 -2.44 -6.83 7.98 5.31 10.33 -3.76 -7.70 8.38 4.85 11.67 -3.20
Vacuole -5.09 -8.56 -14.16 -9.46 -8.53 -12.80 -13.53 -23.56 -14.42 6.16 -14.43 -18.83 -29.52 -17.14 -11.51
Vacuole Periphery -4.70 3.80 -1.66 2.28 -3.38 -7.30 9.96 -2.39 1.18 -3.63 -8.88 10.04 -3.10 2.28 -4.91
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein that interacts with Rab GTPases; localized to late Golgi vesicles; computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport
Localization
Cell Percentages cytoplasm (43%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Yip5

Yip5


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Yip5-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available