Standard name
Human Ortholog
Description Zn(II)2Cys6 family transcription factor; positively regulates sterol uptake genes under anaerobic conditions; involved in hypoxic gene expression; represses filamentation-inducing genes during vegetative growth; positively regulates mating with SUT2 by repressing expression of genes that act as mating inhibitors; repressed by STE12; relocalizes from the nucleus to the cytoplasm upon DNA replication stress; SUT1 has a paralog, SUT2, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 – 0 0 0.05 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – 0 0 – – – – – –
Cell Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm 0.07 0.06 0 – 0.64 0.73 0.65 0.54 0.35 0.39 0.2 0.32 0.14 0.41 0.83 – 0.28 0.23 0 0 0 0 0.09 0.11
Endoplasmic Reticulum 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – 0 0.08 0 0 0 0 0 0
Endosome 0 0 0 – 0 0 0 0 0 0 0 0 0 0.05 0 – 0.12 0.14 0 0 0 0 0 0
Golgi 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 0.09 0.39 0 – 0 0.1 0.2 0.24 0.69 0.55 0.7 0.6 0 0 0 – 0.11 0.06 0 0 0 0 0 0
Nucleus 0.8 0.72 0.88 – 0.23 0.13 0.1 0.23 0.2 0.3 0.35 0.28 0.81 0.41 0.07 – 0.39 0.45 0.68 0.65 0.7 0.61 0.53 0.39
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0.07 0.07 0.05 0.07 0.06 0.07
Peroxisomes 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 – 0 0 0.05 0 0 0 0 0 0 0 0 – 0.07 0.07 0.06 0.05 0.06 0.06 0.06 0.12
Vac/Vac Membrane 0.08 0 0 – 0.14 0 0 0 0 0 0 0 0.05 0.11 0.14 – 0.21 0.16 0.09 0.12 0.08 0.13 0.15 0.16
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 – 0 0 0 1 0 0 0 0 0 0 0 – 0 1 0 0 0 2 0 0
Bud 0 0 0 – 0 0 0 1 1 1 1 2 0 0 0 – 0 1 4 5 0 4 8 6
Bud Neck 0 0 0 – 0 0 4 4 0 0 2 3 1 3 1 – 0 0 0 1 0 1 0 5
Bud Site 0 0 0 – 0 0 0 2 3 2 3 8 0 0 0 – 0 0 – – – – – –
Cell Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – 1 0 0 0 0 0 0 0
Cytoplasm 17 20 1 – 14 22 51 63 54 64 24 69 23 99 244 – 56 30 7 13 0 11 22 29
Endoplasmic Reticulum 0 0 0 – 0 0 1 2 1 0 1 1 0 0 1 – 7 11 0 0 0 2 2 1
Endosome 4 1 0 – 0 0 1 0 1 0 0 1 0 13 4 – 24 18 4 6 0 2 2 8
Golgi 3 0 1 – 0 0 0 0 0 0 0 0 0 0 0 – 1 0 2 1 1 0 0 0
Mitochondria 22 133 1 – 0 3 16 28 107 91 83 128 3 2 1 – 21 8 4 11 0 3 7 9
Nucleus 202 246 29 – 5 4 8 27 31 50 42 59 132 99 20 – 77 59 198 255 46 176 135 108
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1
Nucleolus 6 1 0 – 0 0 0 0 0 2 0 2 1 0 0 – 1 1 20 25 3 20 16 20
Peroxisomes 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 6 10 1 – 0 1 4 5 0 3 0 4 5 3 1 – 14 9 17 18 4 16 15 32
Vac/Vac Membrane 19 13 1 – 3 1 2 3 3 1 5 8 8 26 40 – 42 21 25 47 5 37 38 44
Unique Cell Count 251 340 33 22 30 79 117 156 165 119 214 163 239 295 197 131 292 394 67 288 257 279
Labelled Cell Count 279 424 34 22 31 87 136 201 214 161 285 173 245 312 244 159 292 394 67 288 257 279


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.0 4.0 5.6 – 4.9 4.1 3.9 4.3 3.2 3.4 3.3 3.4 5.4 5.1 4.6 4.5 5.5 5.6 5.8 5.8 5.6
Std Deviation (1e-4) 0.8 0.8 1.0 – 1.3 0.8 1.2 2.0 1.1 0.9 0.8 0.6 0.8 1.1 0.8 1.5 1.6 1.3 1.4 1.6 1.2
Intensity Change (Log2) – – – – -0.19 -0.47 -0.51 -0.37 -0.79 -0.73 -0.77 -0.73 -0.05 -0.15 -0.29 -0.33 -0.03 -0.01 0.04 0.04 -0.0

WT3RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000246WT3HU80HU120HU1600246WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30246WT1AF100AF140AF1800246
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – 0 –
Bud Neck – – – – – – – – – – – – – 0 –
Bud Site – – – – – – – – – – – – – 0 –
Cell Periphery – – – – – – – – – – – – – 0 –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – 0 –
Endosome – – – – – – – – – – – – – 0 –
Golgi – – – – – – – – – – – – – 0 –
Mitochondria – – – – – – – – – – – – – 0 –
Nuclear Periphery – – – – – – – – – – – – – 0 –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – 0 –
Peroxisomes – – – – – – – – – – – – – 0 –
SpindlePole – – – – – – – – – – – – – 0 –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – 0 –
Cytoplasm – – – – – – – – – – – – – 0 –
Nucleus – – – – – – – – – – – – – 0 –
Vacuole – – – – – – – – – – – – – 2.5 –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.8795 3.5722 3.556 2.2762 2.5653 2.8033 3.2936 3.3701 3.3015 2.9482 3.1685 3.2855 1.1009 1.25 1.0491 0.853 0.6036 0.929
Actin 0.0203 0 0.0229 0.0005 0.0121 0.0019 0.0076 0.0005 0.0064 0.0011 0.0001 0.0001 0.0322 0.0001 0.0016 0.0001 0.0001 0.0012
Bud 0.0003 0 0.0004 0.0002 0.0004 0.0001 0.0002 0.0001 0.0002 0.0024 0 0 0.0013 0.0001 0.0002 0 0 0.0001
Bud Neck 0.0009 0.0002 0.0009 0.001 0.0016 0.0034 0.0015 0.001 0.0004 0.001 0.0005 0.0021 0.0032 0.0003 0.0024 0.0052 0.0014 0.0031
Bud Periphery 0.0007 0 0.0012 0.0002 0.0009 0.0002 0.0002 0.0001 0.0002 0.0052 0 0 0.0028 0.0001 0.0002 0 0.0001 0.0002
Bud Site 0.0011 0.0006 0.0029 0.0011 0.0016 0.0002 0.0007 0.0016 0.0006 0.0212 0 0.0001 0.0046 0.0004 0.003 0.0001 0.0001 0.0002
Cell Periphery 0.0002 0 0.0005 0 0.0001 0 0.0001 0 0.0001 0.0026 0 0 0.0007 0 0.0001 0 0 0
Cytoplasm 0.0205 0.0079 0.017 0.0038 0.0079 0.0064 0.0251 0.0193 0.0088 0.0099 0.008 0.0151 0.0293 0.0176 0.0174 0.0119 0.0031 0.0096
Cytoplasmic Foci 0.0032 0.0001 0.008 0.0004 0.0336 0.001 0.0051 0.0045 0.0003 0.0012 0.0002 0.0005 0.0114 0.0005 0.0027 0.0009 0.0001 0.0008
Eisosomes 0.0002 0 0.0002 0 0.0001 0.0001 0.0002 0 0.0002 0.0001 0 0 0.0014 0 0.0001 0 0 0
Endoplasmic Reticulum 0.003 0.0001 0.0021 0.0004 0.0009 0.0004 0.0018 0.0008 0.0006 0.0008 0.0001 0.0004 0.0048 0.0007 0.0005 0.0014 0.0002 0.0009
Endosome 0.0121 0.0001 0.0066 0.0003 0.0241 0.0027 0.0153 0.0009 0.0016 0.0028 0.0001 0.0004 0.0193 0.0007 0.0015 0.0026 0.0003 0.0013
Golgi 0.0023 0 0.0044 0.0001 0.0192 0.0013 0.0048 0.0001 0.0008 0.0012 0 0 0.006 0 0.0008 0 0 0.0002
Lipid Particles 0.0074 0 0.0092 0 0.0712 0.0046 0.0097 0.0002 0.0001 0.0002 0 0 0.0116 0 0.0024 0.0001 0 0.0004
Mitochondria 0.0015 0.0002 0.0062 0.0005 0.0259 0.0005 0.0019 0.0003 0.0023 0.0047 0.0001 0.0002 0.0105 0.0003 0.0006 0.0002 0.0003 0.0006
None 0.0919 0.0307 0.0668 0.0009 0.0249 0.0266 0.1337 0.0145 0.0787 0.0029 0.148 0.0434 0.0889 0.0707 0.0703 0.0015 0.0015 0.0364
Nuclear Periphery 0.0113 0.0023 0.0161 0.0083 0.0266 0.0039 0.0061 0.0136 0.0114 0.0046 0.0063 0.0051 0.0186 0.0062 0.0049 0.0179 0.0094 0.0108
Nucleolus 0.022 0.0146 0.0195 0.0102 0.0787 0.0289 0.0181 0.0149 0.0148 0.0167 0.0174 0.0406 0.0172 0.0145 0.017 0.0167 0.0508 0.027
Nucleus 0.7598 0.9377 0.7728 0.9223 0.5256 0.8985 0.7224 0.7915 0.8546 0.9018 0.8007 0.8504 0.66 0.8664 0.8401 0.9067 0.8535 0.8683
Peroxisomes 0.0016 0 0.012 0 0.0728 0.0009 0.0009 0.0002 0.0001 0.0001 0 0 0.0049 0 0.0053 0 0 0.0001
Punctate Nuclear 0.0305 0.0051 0.0222 0.0496 0.0697 0.0181 0.0421 0.1354 0.0168 0.015 0.0182 0.0412 0.0591 0.0195 0.0284 0.0336 0.0787 0.038
Vacuole 0.0077 0.0003 0.0061 0.0002 0.0011 0.0004 0.002 0.0003 0.0005 0.0041 0.0001 0.0003 0.0103 0.0015 0.0005 0.0007 0.0002 0.0006
Vacuole Periphery 0.0013 0 0.0019 0.0001 0.0009 0.0002 0.0004 0.0001 0.0004 0.0005 0 0.0001 0.0018 0.0002 0.0001 0.0003 0.0001 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.034 14.2477 23.5845 14.0436 7.1531 11.0279 17.1761 11.5927 10.541 12.1888
Translational Efficiency 0.6905 0.82 0.4717 0.7896 1.289 1.147 0.5531 0.8961 0.9143 0.5968

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2111 1531 1777 1659 1805 1822 192 2080 3916 3353 1969 3739

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 786.33 833.23 823.35 853.62 699.63 822.41 930.63 883.44 746.37 827.35 833.81 870.21
Standard Deviation 88.03 112.46 141.27 114.72 85.81 106.50 96.85 109.16 97.16 109.40 141.20 112.64
Intensity Change Log 2 — 0.083580 0.066371 0.118459 — 0.233266 0.411616 0.336540 — 0.155994 0.239237 0.225252

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000049 0.000689 0.000757 0.000661 0.000183 0.000293 0.000859 0.000576 0.000111 0.000474 0.000767 0.000614
Bud Neck 0.003523 0.010246 0.014266 0.015916 0.003942 0.009542 0.002860 0.018890 0.003716 0.009863 0.013154 0.017570
Bud Site 0.000306 0.003005 0.003989 0.011176 0.001377 0.003783 0.004558 0.018514 0.000800 0.003427 0.004044 0.015258
Cell Periphery 0.000069 0.000122 0.000137 0.000163 0.000081 0.000104 0.000136 0.000226 0.000074 0.000112 0.000137 0.000198
Cytoplasm 0.035815 0.025398 0.020751 0.103603 0.060067 0.041534 0.016733 0.157760 0.046993 0.034166 0.020359 0.133731
Cytoplasmic Foci 0.004276 0.003449 0.000446 0.003597 0.006017 0.009509 0.001264 0.004551 0.005079 0.006742 0.000525 0.004128
Eisosomes 0.000016 0.000033 0.000021 0.000032 0.000021 0.000031 0.000071 0.000033 0.000018 0.000032 0.000026 0.000033
Endoplasmic Reticulum 0.000892 0.004760 0.004222 0.007075 0.001675 0.002207 0.008108 0.005323 0.001253 0.003373 0.004601 0.006101
Endosome 0.000430 0.001039 0.000448 0.003334 0.000658 0.002152 0.000886 0.003678 0.000535 0.001644 0.000491 0.003525
Golgi 0.000235 0.000523 0.000139 0.001710 0.000374 0.001564 0.000084 0.001275 0.000299 0.001088 0.000134 0.001468
Lipid Particles 0.001584 0.001373 0.000508 0.000586 0.001495 0.003002 0.001492 0.000748 0.001543 0.002258 0.000604 0.000676
Mitochondria 0.003205 0.003075 0.001181 0.004391 0.003948 0.006533 0.000943 0.005846 0.003548 0.004954 0.001158 0.005200
Mitotic Spindle 0.001163 0.003830 0.003029 0.020448 0.002186 0.007524 0.000419 0.026674 0.001634 0.005837 0.002775 0.023911
None 0.005756 0.009547 0.007426 0.011447 0.015971 0.011012 0.003638 0.008793 0.010465 0.010343 0.007056 0.009971
Nuclear Periphery 0.001989 0.001705 0.000715 0.003106 0.001443 0.001536 0.000950 0.002788 0.001737 0.001613 0.000738 0.002929
Nuclear Periphery Foci 0.000232 0.001500 0.000571 0.000957 0.000754 0.001308 0.000657 0.000485 0.000472 0.001396 0.000579 0.000694
Nucleolus 0.016278 0.032740 0.008836 0.003684 0.015117 0.021323 0.008328 0.003073 0.015743 0.026536 0.008787 0.003344
Nucleus 0.922051 0.892860 0.929689 0.780333 0.881944 0.869833 0.933300 0.708125 0.903564 0.880347 0.930041 0.740164
Peroxisomes 0.000965 0.001329 0.000191 0.000568 0.001010 0.003957 0.000433 0.000306 0.000986 0.002757 0.000215 0.000423
Vacuole 0.000997 0.002238 0.002529 0.023367 0.001279 0.002472 0.014118 0.030573 0.001127 0.002365 0.003659 0.027375
Vacuole Periphery 0.000170 0.000539 0.000149 0.003845 0.000456 0.000782 0.000163 0.001762 0.000302 0.000671 0.000150 0.002686

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -13.22 -22.01 -17.08 -0.33 2.36 -2.32 -6.47 -8.78 -7.10 3.75 -11.46 -19.63 -17.75 -4.96 4.75
Bud Neck -8.31 -12.82 -10.48 -4.53 0.73 -5.71 -0.93 -14.46 -8.19 -12.40 -9.55 -13.13 -17.81 -9.24 -2.02
Bud Site -4.46 -4.92 -6.89 -3.84 -2.93 -2.39 -1.73 -8.76 -6.08 -2.98 -4.47 -4.56 -11.31 -7.22 -5.88
Cell Periphery -4.51 -4.71 -6.11 -0.34 -0.05 -2.53 -2.53 -5.98 -3.94 0.17 -5.14 -5.17 -8.32 -3.36 -1.12
Cytoplasm 3.21 6.97 -11.51 -13.57 -16.41 4.24 6.77 -12.82 -17.33 -17.55 4.69 11.97 -18.05 -21.97 -27.83
Cytoplasmic Foci 0.64 7.16 4.00 2.85 -4.27 -2.87 6.35 4.46 6.41 -3.19 -2.36 10.57 5.81 6.95 -7.53
Eisosomes -8.74 -5.31 -13.50 -3.35 -9.71 -4.16 -8.78 -9.33 -4.00 6.63 -9.17 -7.53 -16.56 -5.20 -6.44
Endoplasmic Reticulum -16.01 -20.12 -20.74 -8.06 -8.86 -2.52 -7.03 -17.48 -15.57 3.46 -14.22 -18.00 -27.63 -16.03 -6.47
Endosome -3.40 -0.46 -5.40 -2.52 -5.29 -4.28 -2.67 -5.26 -0.43 -1.86 -5.47 -0.22 -7.59 -1.73 -7.44
Golgi -1.57 0.85 -1.48 -0.34 -1.86 -2.94 2.12 -0.80 2.35 -2.25 -3.37 1.92 -1.72 1.81 -2.78
Lipid Particles 0.33 4.06 4.16 3.14 -1.31 -2.76 -0.96 3.79 4.47 3.81 -2.18 4.42 5.49 5.37 -1.13
Mitochondria 0.12 2.48 0.14 0.05 -3.24 -2.06 3.18 -0.19 2.25 -5.15 -1.85 3.89 -0.17 2.01 -5.98
Mitotic Spindle -2.89 -3.10 -8.01 -6.30 -5.84 -3.32 -0.75 -8.78 -5.65 -4.48 -4.43 -2.82 -11.97 -8.31 -8.68
None -3.71 -0.36 -2.10 1.29 -1.51 2.92 7.95 6.59 4.25 -3.53 0.06 4.74 3.93 3.99 -1.73
Nuclear Periphery 0.88 4.47 -8.36 -11.38 -16.63 -0.39 -1.50 -12.43 -11.71 -10.14 0.61 4.93 -13.87 -16.26 -22.78
Nuclear Periphery Foci -5.22 -2.74 -6.83 2.22 -3.87 -0.85 -0.50 0.87 1.82 1.58 -4.08 -0.16 -2.54 2.87 -2.77
Nucleolus -7.30 4.62 11.21 17.21 8.42 -3.98 4.50 10.68 13.40 2.52 -7.77 5.46 15.34 21.60 8.91
Nucleus 5.49 -1.24 18.17 12.96 19.35 1.98 -0.60 19.71 17.11 12.08 5.45 -4.76 27.68 21.48 30.88
Peroxisomes -1.18 2.19 1.95 4.41 -1.15 -3.96 2.03 2.70 5.52 3.34 -4.07 3.31 3.21 6.62 -0.59
Vacuole -3.26 -3.52 -15.17 -14.62 -14.23 -2.56 -5.90 -19.04 -18.57 -2.62 -4.15 -6.42 -24.34 -23.61 -20.24
Vacuole Periphery -3.67 0.30 -2.34 -1.64 -2.36 -1.47 1.84 -1.54 -0.25 -2.99 -3.03 2.09 -2.92 -1.54 -3.51
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Zn(II)2Cys6 family transcription factor; positively regulates sterol uptake genes under anaerobic conditions; involved in hypoxic gene expression; represses filamentation-inducing genes during vegetative growth; positively regulates mating with SUT2 by repressing expression of genes that act as mating inhibitors; repressed by STE12; relocalizes from the nucleus to the cytoplasm upon DNA replication stress; SUT1 has a paralog, SUT2, that arose from the whole genome duplication
Localization
Cell Percentages nucleus (98%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Sut1

Sut1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sut1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available