Standard name
Human Ortholog
Description Zeta subunit of the oligosaccharyltransferase complex of the ER lumen; complex catalyzes asparagine-linked glycosylation of newly synthesized proteins
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0.08 0 0 0 0 0 0
Cytoplasm 0.93 0.95 0.95 0.92 0.9 0.75 0.7 0.65 0.65 0.67 0.58 0.63 0.9 0.97 0.98 0.92 0.9 0.88 0.61 0.71 0.61 0.58 0.64 0.61
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0 0 0.05 0.08 0.07 0.15 0.07 0.14 0.09 0.06 0.07
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0.09 0.32 0.45 0.48 0.51 0.41 0.58 0.53 0 0 0 0 0 0 0.07 0.06 0.1 0.14 0.1 0.12
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0.05 0 0 0 0.07 0.05 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 2 1 0 0 1 1 0 0 0 0 0 0 2 0 0 4 3 3 27 12 12 5 4 10
Bud 1 3 2 0 1 3 10 14 14 4 20 11 0 0 0 2 1 0 28 15 6 9 10 15
Bud Neck 6 3 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 3 10 9 4 5 5 5
Bud Site 0 0 0 0 0 0 0 1 6 2 2 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 5 2 4 5 2 1 2 0 4 3 3 3 6 3 7 19 7 22 16 7 10 4 4 4
Cytoplasm 806 442 372 275 384 350 415 402 370 307 388 350 445 386 594 314 202 248 562 354 246 206 209 228
Endoplasmic Reticulum 17 10 9 1 3 18 4 1 3 2 8 7 50 7 5 17 17 19 142 33 56 32 18 25
Endosome 6 0 2 2 8 2 2 2 4 10 1 2 1 1 1 0 2 1 15 7 6 2 6 4
Golgi 3 2 0 0 0 0 0 0 0 0 0 0 1 0 2 0 0 1 2 3 2 2 1 5
Mitochondria 9 4 13 13 38 152 263 294 289 187 393 299 1 0 0 6 5 6 62 31 41 50 32 44
Nucleus 1 0 0 1 3 2 4 8 0 1 5 3 1 1 1 2 1 1 0 0 0 0 0 0
Nuclear Periphery 0 1 0 1 1 1 3 3 0 1 1 0 0 0 0 0 0 0 2 0 1 0 3 0
Nucleolus 0 0 1 0 1 2 1 2 3 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 1 0 1 0 0 0 3 0 1 0 0 0 0 0 0 1 0 0 0 0 0
SpindlePole 0 1 2 3 0 2 6 2 6 4 3 9 0 0 1 0 0 0 13 5 1 2 3 3
Vac/Vac Membrane 27 5 3 11 16 6 13 11 21 23 11 10 14 6 8 8 8 14 20 13 5 23 16 20
Unique Cell Count 864 465 392 298 427 469 589 616 572 457 672 559 496 396 608 342 224 283 928 503 403 356 329 374
Labelled Cell Count 883 474 408 313 458 541 723 740 720 547 838 696 521 406 619 372 247 318 928 503 403 356 329 374


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.5 4.3 4.1 4.3 4.1 3.9 3.2 3.5 3.4 3.4 3.2 3.3 5.8 5.6 5.5 6.1 5.9 6.3 6.0 6.2 5.8
Std Deviation (1e-4) 0.9 0.9 0.9 1.5 1.5 1.2 0.9 1.3 1.1 1.0 0.8 0.7 1.3 1.4 1.4 1.0 1.2 1.2 1.8 2.2 1.8
Intensity Change (Log2) – – – 0.08 0.02 -0.07 -0.34 -0.22 -0.27 -0.25 -0.33 -0.31 0.51 0.46 0.44 0.58 0.54 0.64 0.57 0.6 0.52

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 – 0
Bud Neck – – – – – – – – – – – – 0 – 0
Bud Site – – – – – – – – – – – – 0 – 0
Cell Periphery – – – – – – – – – – – – 0 – 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 – 0
Endosome – – – – – – – – – – – – 0 – 0
Golgi – – – – – – – – – – – – 0 – 0
Mitochondria – – – – – – – – – – – – 0 – 0
Nuclear Periphery – – – – – – – – – – – – 0 – 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 – 0
Peroxisomes – – – – – – – – – – – – 0 – 0
SpindlePole – – – – – – – – – – – – 0 – 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 – 0
Cytoplasm – – – – – – – – – – – – 0 – 0
Nucleus – – – – – – – – – – – – 0 – 0
Vacuole – – – – – – – – – – – – 1.8 – 3.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.1137 0.7678 0.5463 0.3929 0.324 0.7196 2.3179 3.2555 2.8978 3.1483 2.7004 3.1808 2.416 1.2832 1.3303 1.9245 2.6851 1.2405
Actin 0.0007 0.0038 0.0018 0.0035 0.0002 0.0021 0.0088 0.0005 0.0003 0.0019 0.0007 0.0009 0.0393 0.0005 0.0122 0.0272 0.002 0.0007
Bud 0.0018 0.0033 0.0015 0.0001 0 0.0041 0.0001 0.0003 0.0004 0.0003 0 0.0001 0.0011 0.0024 0.0001 0.0004 0.0018 0.0001
Bud Neck 0.0006 0.0016 0.0006 0.0004 0.0001 0.0042 0.0011 0.0002 0.0003 0.0009 0.0002 0.0011 0.0067 0.0001 0.0001 0.0012 0.0002 0.0005
Bud Periphery 0.0012 0.0011 0.0007 0.0002 0 0.0014 0.0001 0.0003 0.0005 0.0004 0 0.0002 0.0017 0.0024 0.0001 0.0007 0.0041 0.0001
Bud Site 0.002 0.0041 0.0062 0.0008 0.0001 0.0011 0.0006 0.0081 0.0021 0.0002 0 0.0006 0.0083 0.0051 0.0003 0.0017 0.0005 0.0002
Cell Periphery 0.0003 0.0004 0.0002 0.0004 0.0001 0.0002 0.0005 0.0006 0.0006 0.0012 0.0001 0.0002 0.0008 0.0005 0.0003 0.0002 0.0003 0.0002
Cytoplasm 0.1162 0.137 0.1321 0.1469 0.0574 0.1278 0.1897 0.2635 0.2756 0.4378 0.2734 0.2502 0.1286 0.3007 0.2931 0.2138 0.2429 0.3801
Cytoplasmic Foci 0.0124 0.0072 0.0046 0.0132 0.0022 0.0073 0.0092 0.0064 0.0073 0.0096 0.0578 0.0066 0.0402 0.0055 0.0206 0.0083 0.0023 0.006
Eisosomes 0.0002 0.0003 0.0001 0.0002 0.0001 0.0001 0.0015 0.0001 0.0001 0.0002 0.0001 0.0001 0.001 0.0001 0.0001 0.0007 0.0001 0.0001
Endoplasmic Reticulum 0.0092 0.0115 0.007 0.0202 0.0008 0.008 0.0271 0.0398 0.042 0.089 0.0522 0.0194 0.0351 0.0331 0.0306 0.0858 0.0092 0.0414
Endosome 0.0022 0.0031 0.0023 0.0053 0.0009 0.0011 0.0052 0.0057 0.0101 0.0183 0.0036 0.0044 0.0333 0.0038 0.0134 0.0313 0.0071 0.0056
Golgi 0.0002 0.0004 0.0003 0.0008 0 0.0001 0.0009 0.0003 0.0003 0.0006 0.0003 0.0002 0.0082 0.0003 0.0047 0.0101 0.0003 0.0006
Lipid Particles 0.0007 0.0007 0.0005 0.0021 0.0002 0.0003 0.0018 0.0007 0.0014 0.0027 0.0009 0.0012 0.0196 0.0008 0.0041 0.013 0.0003 0.0008
Mitochondria 0.0004 0.0009 0.0003 0.0006 0.0002 0.001 0.0003 0.0003 0.0004 0.0016 0.0004 0.0002 0.0228 0.0004 0.0016 0.0035 0.003 0.0004
None 0.8421 0.8086 0.8184 0.792 0.932 0.8232 0.7458 0.6627 0.6453 0.3987 0.5997 0.7074 0.5744 0.6362 0.5997 0.5428 0.5894 0.5477
Nuclear Periphery 0.0016 0.0021 0.0022 0.0021 0.0014 0.001 0.0018 0.0029 0.0034 0.016 0.0021 0.0021 0.0272 0.0023 0.006 0.0277 0.0513 0.0041
Nucleolus 0.0008 0.0012 0.001 0.0004 0.0003 0.0019 0.0002 0.0003 0.0005 0.0005 0.0001 0.0001 0.0042 0.0003 0.0002 0.0014 0.001 0.0003
Nucleus 0.0027 0.0062 0.0086 0.0027 0.002 0.0069 0.0016 0.003 0.0029 0.0092 0.0007 0.0016 0.0076 0.002 0.0013 0.0072 0.0627 0.0028
Peroxisomes 0.0001 0.0003 0.0002 0.0023 0.0001 0.0003 0.0003 0.0002 0.0001 0.0004 0.0006 0.0001 0.0113 0.0001 0.0019 0.006 0.0001 0.0003
Punctate Nuclear 0.0033 0.0048 0.0102 0.0047 0.0014 0.0068 0.0011 0.0012 0.0016 0.0042 0.0057 0.0017 0.0219 0.001 0.0071 0.0099 0.0024 0.0064
Vacuole 0.0012 0.0013 0.0008 0.0011 0.0005 0.0008 0.0021 0.0027 0.0045 0.0053 0.0013 0.0012 0.0045 0.0024 0.0018 0.0052 0.0103 0.0017
Vacuole Periphery 0.0001 0.0002 0.0001 0.0001 0.0001 0.0002 0.0002 0.0002 0.0003 0.0011 0.0002 0.0001 0.0023 0.0002 0.0005 0.0015 0.0087 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 114.1453 83.1428 64.4999 87.167 87.7004 54.9284 95.5291 73.5023 82.1201 99.3441
Translational Efficiency 1.521 1.8119 2.041 1.4077 1.7591 3.5951 1.8592 1.9649 1.7745 2.0556

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1070 1572 156 1910 1956 1532 1185 81 3026 3104 1341 1991

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 665.27 722.01 860.15 796.65 685.12 702.15 824.92 858.93 678.10 712.21 829.02 799.18
Standard Deviation 80.56 99.88 87.23 107.95 81.78 99.85 104.10 113.26 81.90 100.36 102.90 108.87
Intensity Change Log 2 — 0.118079 0.370648 0.260006 — 0.035423 0.267898 0.326184 — 0.076735 0.319432 0.293961

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000078 0.000369 0.000363 0.001359 0.000055 0.000597 0.000429 0.000178 0.000063 0.000481 0.000421 0.001311
Bud Neck 0.005787 0.016387 0.001658 0.009509 0.009810 0.027889 0.004890 0.000937 0.008387 0.022064 0.004514 0.009161
Bud Site 0.004273 0.014805 0.003929 0.026196 0.001967 0.012190 0.013128 0.001557 0.002783 0.013514 0.012058 0.025193
Cell Periphery 0.000365 0.000872 0.000419 0.000320 0.000138 0.000394 0.000331 0.000798 0.000218 0.000636 0.000341 0.000340
Cytoplasm 0.562874 0.493397 0.285062 0.475971 0.539836 0.435172 0.469345 0.409331 0.547982 0.464660 0.447907 0.473260
Cytoplasmic Foci 0.190739 0.192507 0.080217 0.027271 0.177304 0.236877 0.034478 0.124757 0.182055 0.214406 0.039799 0.031237
Eisosomes 0.000136 0.000203 0.000176 0.000074 0.000146 0.000423 0.000084 0.000238 0.000142 0.000312 0.000094 0.000081
Endoplasmic Reticulum 0.000554 0.005434 0.025458 0.015040 0.002280 0.011050 0.039501 0.052876 0.001670 0.008206 0.037868 0.016579
Endosome 0.007511 0.012790 0.013308 0.004386 0.007690 0.022324 0.004218 0.014325 0.007627 0.017496 0.005275 0.004790
Golgi 0.000843 0.002103 0.000176 0.001272 0.000920 0.006094 0.000140 0.000712 0.000893 0.004073 0.000144 0.001249
Lipid Particles 0.007130 0.012342 0.014218 0.004122 0.009655 0.027019 0.006688 0.017933 0.008762 0.019586 0.007564 0.004684
Mitochondria 0.001161 0.003092 0.000283 0.001231 0.003640 0.008342 0.000365 0.000227 0.002763 0.005683 0.000356 0.001190
Mitotic Spindle 0.000568 0.002891 0.000108 0.010260 0.001853 0.002836 0.003213 0.000021 0.001398 0.002864 0.002852 0.009843
None 0.006374 0.005625 0.001822 0.003542 0.003903 0.002429 0.002084 0.003306 0.004777 0.004048 0.002053 0.003532
Nuclear Periphery 0.000373 0.000831 0.011904 0.004232 0.001000 0.001740 0.009371 0.004431 0.000778 0.001280 0.009665 0.004240
Nuclear Periphery Foci 0.000631 0.001503 0.033784 0.005539 0.000691 0.002299 0.015233 0.018953 0.000670 0.001896 0.017391 0.006084
Nucleolus 0.001058 0.001296 0.001492 0.000586 0.001109 0.001457 0.000369 0.001178 0.001091 0.001375 0.000500 0.000610
Nucleus 0.174855 0.159353 0.390962 0.295565 0.187955 0.118183 0.319849 0.242115 0.183323 0.139033 0.328121 0.293391
Peroxisomes 0.001993 0.007188 0.000938 0.000564 0.002644 0.012565 0.000500 0.000878 0.002414 0.009842 0.000551 0.000577
Vacuole 0.031943 0.065887 0.133372 0.112617 0.046766 0.068835 0.075595 0.104964 0.041524 0.067342 0.082317 0.112306
Vacuole Periphery 0.000754 0.001124 0.000351 0.000344 0.000638 0.001283 0.000189 0.000287 0.000679 0.001203 0.000208 0.000342

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.17 -5.21 -2.63 -1.79 -1.72 -3.69 -1.98 -3.78 2.74 1.25 -5.20 -2.18 -2.69 -1.43 -1.52
Bud Neck -7.03 5.66 -2.84 4.80 -8.55 -8.01 4.06 9.95 12.99 5.41 -9.89 4.05 -0.15 9.26 -3.75
Bud Site -5.14 0.27 -7.33 -2.14 -6.06 -6.75 -4.15 0.80 7.08 4.32 -8.58 -3.81 -8.48 -2.82 -3.08
Cell Periphery -2.65 -0.53 1.15 3.56 4.09 -3.59 -7.63 -4.88 -2.55 -3.41 -4.26 -3.03 -1.85 3.69 1.65
Cytoplasm 7.28 15.03 13.12 5.78 -8.69 11.66 8.86 5.29 1.47 2.12 12.75 13.33 14.63 3.42 -0.46
Cytoplasmic Foci -0.16 11.54 29.52 33.69 6.26 -8.81 33.01 3.85 7.80 -6.70 -6.48 38.59 43.95 48.56 4.26
Eisosomes -4.28 -3.59 9.41 8.63 8.25 -8.22 6.89 -3.06 3.93 -4.97 -9.07 6.46 9.76 12.57 2.89
Endoplasmic Reticulum -5.18 -4.23 -9.52 -4.28 2.02 -5.41 -9.45 -2.92 -2.35 -0.76 -6.89 -10.24 -8.71 -3.22 6.10
Endosome -4.92 -3.68 5.34 10.33 6.50 -9.03 6.54 -3.10 2.99 -4.85 -10.25 4.98 7.39 14.64 2.71
Golgi -4.05 3.52 0.01 2.26 -1.35 -7.21 6.73 0.97 7.22 -1.99 -8.23 7.45 0.14 5.35 -1.46
Lipid Particles -5.05 -3.77 5.43 10.50 6.14 -9.55 4.76 -2.77 3.10 -4.03 -10.34 2.61 9.58 15.65 6.11
Mitochondria -3.34 2.17 0.28 4.47 -3.56 -3.35 4.18 4.37 7.04 3.23 -3.60 4.56 3.14 7.32 -3.14
Mitotic Spindle -2.17 1.05 -6.29 -4.03 -6.64 -1.05 -1.59 2.46 3.91 3.38 -1.90 -1.92 -5.52 -4.36 -3.43
None 0.63 4.90 3.12 2.94 -2.48 1.96 2.96 0.51 -0.51 -0.85 1.07 5.31 2.27 1.42 -2.44
Nuclear Periphery -5.61 -3.36 -12.14 -10.41 2.04 -2.79 -6.32 -1.75 -1.33 2.13 -3.42 -7.19 -10.68 -8.77 4.02
Nuclear Periphery Foci -5.26 -4.25 -8.42 -6.47 3.59 -3.68 -9.16 -3.92 -3.53 -0.74 -5.23 -10.02 -9.08 -6.34 6.45
Nucleolus -1.43 -1.46 3.68 5.49 3.87 -1.00 3.67 -0.18 0.64 -2.46 -1.37 4.10 3.75 5.10 -0.46
Nucleus 2.52 -9.55 -15.43 -18.05 4.53 13.79 -17.08 -2.72 -5.56 2.84 11.13 -20.15 -16.36 -23.76 5.59
Peroxisomes -6.64 3.43 5.12 9.39 4.47 -8.74 6.98 5.75 10.68 -2.46 -10.74 7.87 8.90 14.40 0.36
Vacuole -12.02 -9.21 -26.71 -18.76 -1.20 -7.42 -10.26 -4.73 -3.18 -1.58 -12.44 -14.03 -25.63 -19.77 -11.54
Vacuole Periphery -0.96 1.44 1.69 4.35 1.44 -3.97 4.59 3.51 7.08 -2.03 -3.06 3.87 3.28 7.54 -1.41
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Zeta subunit of the oligosaccharyltransferase complex of the ER lumen; complex catalyzes asparagine-linked glycosylation of newly synthesized proteins
Localization
Cell Percentages cytoplasm (42%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Ost5

Ost5


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ost5-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available