Standard name
Human Ortholog
Description Putative tRNA acetyltransferase; RNA-binding protein required for the formation of the modified nucleoside N(4)-acetylcytidine in serine and leucine tRNAs but not required for the same modification in 18S rRNA; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.06 0 0.05 0.07 0.06 0 0 0 0.1 0.14 0.14 0.08 0.07 0.11 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.08 0.16 0.09 0.12 0.1 0.56 0.23 0.37 0.34 0 0 0 0.05 0 0 0 0 0 0 0 0
Nucleus 0.95 0.92 0.94 0.93 0.87 0.89 0.87 0.82 0.72 0.83 0.8 0.82 0.88 0.85 0.83 0.89 0.85 0.84 0.85 0.86 0.85 0.69 0.6 0.54
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0.05 0 0.05 0 0 0 0 0 0 0 0 0 0 0.07 0.08 0.11
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0.05 0.06 0.13 0.19 0.2
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0
Bud 0 0 0 0 5 0 0 6 9 9 6 0 0 0 2 0 0 1 4 6 3 3 0 3
Bud Neck 0 0 1 0 1 0 0 0 2 1 1 0 1 0 0 0 0 0 0 0 0 0 1 3
Bud Site 1 0 0 2 1 6 3 4 22 20 23 25 0 0 0 0 2 0 – – – – – –
Cell Periphery 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 5 25 19 20 27 25 34 56 41 19 16 12 51 71 71 28 27 28 3 4 1 6 6 5
Endoplasmic Reticulum 1 2 0 0 0 0 0 1 0 0 0 0 0 0 1 5 8 9 0 0 1 1 2 0
Endosome 1 0 0 0 0 5 4 6 0 2 1 0 3 0 1 0 3 1 1 5 4 7 6 9
Golgi 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 1 1 7 0 2 1 0
Mitochondria 12 28 1 38 71 62 86 73 385 161 206 199 0 1 1 18 8 3 0 6 4 7 11 12
Nucleus 271 588 430 427 380 587 630 616 495 591 444 489 446 442 429 319 311 224 256 575 402 285 215 247
Nuclear Periphery 0 5 0 0 0 6 10 7 9 17 6 4 2 5 1 12 10 8 0 0 1 3 4 13
Nucleolus 7 6 1 2 4 2 7 19 31 25 28 13 1 4 5 8 6 5 13 18 16 29 29 52
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0
SpindlePole 0 1 4 2 4 3 3 10 6 5 5 2 1 3 6 2 3 3 3 2 4 5 6 8
Vac/Vac Membrane 6 16 5 7 8 18 16 29 12 16 9 12 5 4 7 7 18 11 12 34 28 55 66 93
Unique Cell Count 286 642 457 460 436 658 728 748 688 709 555 594 504 519 517 358 365 266 300 671 476 413 358 458
Labelled Cell Count 304 671 462 499 501 715 793 827 1012 866 745 756 511 530 525 399 396 294 300 671 476 413 358 458


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.1 5.7 6.7 5.8 5.2 5.4 5.3 5.6 4.2 5.0 4.6 4.8 6.7 6.5 6.2 6.7 8.1 8.2 6.9 7.4 7.2
Std Deviation (1e-4) 1.2 1.0 1.3 1.2 1.4 1.3 1.2 1.4 1.1 0.9 1.0 0.8 1.5 1.3 1.3 1.4 2.0 2.3 1.5 1.5 1.5
Intensity Change (Log2) – – – -0.21 -0.35 -0.3 -0.33 -0.25 -0.66 -0.43 -0.54 -0.49 0.0 -0.04 -0.1 -0.0 0.28 0.29 0.06 0.14 0.11

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 3.6 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.1 1.4 -0.3 0.4 2.3 1.3 -1.4 -1.1 -2.0 3.6 5.1 5.1 2.2 2.0 3.3
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 6.0 8.8 6.5 7.4 6.7 0 10.8 0 0 0 0 0 4.5 0 0
Nucleus -0.8 -3.6 -2.8 -4.1 -5.8 -9.3 -5.4 -6.5 -5.7 -3.1 -4.5 -5.4 -2.6 -4.2 -4.4
Nuclear Periphery 0 0 0 0 0 0 3.3 0 0 0 0 0 3.9 0 0
Nucleolus 0 0 0 0 3.1 0 3.7 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0.7 0 0 0 0 0 0 0 0 0 0
Vacuole 0.6 0.9 1.9 1.4 2.8 0.9 1.5 0.7 1.2 0 0 0.4 1.0 3.3 2.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.6596 4.2869 3.764 3.5856 3.1801 3.7068 7.5824 6.9073 7.486 7.6629 7.044 7.3078 4.5848 4.4793 4.0759 4.6715 3.7827 4.4499
Actin 0.0246 0 0.0004 0.0026 0.0433 0.0004 0.0165 0.0004 0.0015 0.0001 0.0002 0.0035 0.0003 0 0 0 0 0
Bud 0.0003 0.0001 0 0.0004 0.0005 0.0001 0.0002 0.0008 0.0001 0.0001 0.0001 0.0001 0 0 0 0 0 0
Bud Neck 0.0058 0.0002 0.0006 0.0012 0.0009 0.0014 0.0006 0.0009 0.0058 0.0007 0.0011 0.0012 0.0004 0.0001 0.0001 0.0003 0.0002 0.0009
Bud Periphery 0.0007 0.0001 0.0001 0.0009 0.0007 0.0001 0.0004 0.0014 0.0002 0.0005 0.0001 0.0005 0.0001 0 0 0.0001 0.0001 0.0001
Bud Site 0.0049 0.0002 0.0002 0.0049 0.0019 0.0002 0.0008 0.0035 0.0035 0.0004 0.0006 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001
Cell Periphery 0.0004 0 0.0001 0.0004 0.0001 0.0001 0.0001 0.0004 0.0002 0.0001 0.0001 0.0001 0 0 0 0.0001 0 0
Cytoplasm 0.0016 0.0001 0.0003 0.0026 0.0004 0.0001 0.0063 0.0046 0.0003 0.0001 0.0007 0.0003 0.0008 0.0001 0 0.0001 0 0
Cytoplasmic Foci 0.0157 0 0.0023 0.0309 0.0026 0.0014 0.0068 0.0003 0.0068 0 0.015 0.0001 0.0001 0 0 0 0 0
Eisosomes 0.0004 0 0.0002 0.0001 0.0002 0 0.0002 0 0 0 0.0003 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0006 0 0.0007 0.0049 0.0044 0 0.0019 0.0001 0.0001 0.0001 0.0002 0.0013 0.0006 0 0 0 0 0
Endosome 0.0088 0 0.0026 0.0388 0.0209 0.0008 0.0165 0.0007 0.0032 0.0001 0.0009 0.0005 0.0008 0 0 0 0 0
Golgi 0.0057 0 0.0006 0.0076 0.0124 0.0006 0.0073 0.0002 0.0021 0 0.0002 0.0001 0.0001 0 0 0 0 0
Lipid Particles 0.014 0 0.0068 0.0739 0.0023 0.0125 0.0209 0.0002 0.0074 0 0.0014 0.0001 0.0002 0 0 0 0 0
Mitochondria 0.0103 0.0003 0.0017 0.0032 0.005 0.0087 0.0091 0.0054 0.0039 0.001 0.0012 0.0002 0.0003 0.0001 0.0001 0.0001 0.0002 0.0001
None 0.0039 0 0.0024 0.0016 0.0005 0.0001 0.0027 0.0002 0.0004 0.0001 0.0325 0.0002 0.0002 0 0 0 0 0
Nuclear Periphery 0.0019 0.001 0.003 0.0398 0.0108 0.0004 0.0105 0.0104 0.001 0.0491 0.0054 0.0033 0.0146 0.0007 0.0005 0.0025 0.0004 0.0003
Nucleolus 0.0527 0.0614 0.0779 0.1272 0.0795 0.1039 0.0389 0.1011 0.0351 0.0593 0.1086 0.0871 0.0254 0.0469 0.0453 0.1041 0.1139 0.1011
Nucleus 0.8127 0.9358 0.8951 0.625 0.8072 0.858 0.8331 0.8611 0.9173 0.8868 0.7988 0.895 0.9515 0.9502 0.9531 0.8899 0.8844 0.896
Peroxisomes 0.0176 0 0.0018 0.0132 0.0017 0.01 0.003 0.0005 0.0083 0 0.0005 0 0 0 0 0 0 0
Punctate Nuclear 0.015 0.0005 0.0015 0.0127 0.0015 0.0008 0.0202 0.001 0.0019 0.0005 0.0319 0.0057 0.0037 0.0016 0.0005 0.002 0.0006 0.001
Vacuole 0.0018 0.0002 0.001 0.006 0.0009 0.0003 0.0021 0.0056 0.0008 0.0006 0.0003 0.0005 0.0003 0.0001 0.0001 0.0005 0.0001 0.0002
Vacuole Periphery 0.0006 0.0001 0.0007 0.0021 0.0021 0.0002 0.0018 0.0012 0.0002 0.0004 0.0001 0.0002 0.0003 0 0 0.0001 0.0001 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 41.2191 45.3506 46.2717 46.1473 47.6871 27.8867 49.5796 42.9408 42.2044 47.9414
Translational Efficiency 1.4763 1.463 1.4013 1.548 1.4002 2.4211 1.3207 1.5587 1.4933 1.52

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2311 1504 2622 1504 2031 2285 2342 1571 4342 3789 4964 3075

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 753.83 822.63 927.02 999.14 726.00 903.58 928.97 1056.02 740.81 871.45 927.94 1028.20
Standard Deviation 105.98 127.39 145.95 168.03 97.60 117.39 147.04 172.24 103.08 127.75 146.47 172.55
Intensity Change Log 2 — 0.126004 0.298361 0.406448 — 0.315683 0.355662 0.540596 — 0.222177 0.326757 0.473819

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000137 0.000428 0.000498 0.000823 0.000072 0.000150 0.000564 0.000923 0.000106 0.000260 0.000529 0.000874
Bud Neck 0.005334 0.010539 0.030786 0.028305 0.002654 0.007763 0.026963 0.040029 0.004080 0.008865 0.028982 0.034295
Bud Site 0.001501 0.002031 0.001968 0.003101 0.000313 0.001510 0.001498 0.004589 0.000945 0.001717 0.001746 0.003861
Cell Periphery 0.000664 0.000229 0.000104 0.000345 0.000168 0.000267 0.000136 0.000134 0.000432 0.000252 0.000119 0.000237
Cytoplasm 0.018453 0.005837 0.001646 0.004140 0.007011 0.008622 0.002249 0.003444 0.013101 0.007517 0.001931 0.003785
Cytoplasmic Foci 0.001453 0.001191 0.000065 0.001564 0.001236 0.001552 0.000135 0.001045 0.001351 0.001409 0.000098 0.001299
Eisosomes 0.000021 0.000025 0.000034 0.000031 0.000015 0.000021 0.000037 0.000036 0.000018 0.000022 0.000036 0.000033
Endoplasmic Reticulum 0.006464 0.008582 0.004593 0.004350 0.002769 0.006933 0.005527 0.004944 0.004735 0.007587 0.005034 0.004653
Endosome 0.000655 0.001013 0.000306 0.001768 0.000410 0.001161 0.000494 0.001637 0.000541 0.001102 0.000395 0.001701
Golgi 0.000312 0.000499 0.000058 0.000889 0.000281 0.000261 0.000148 0.002153 0.000297 0.000356 0.000100 0.001535
Lipid Particles 0.000312 0.000296 0.000179 0.000386 0.000467 0.000713 0.000185 0.000753 0.000385 0.000547 0.000182 0.000574
Mitochondria 0.001512 0.001862 0.001611 0.003653 0.001403 0.002786 0.001615 0.004138 0.001461 0.002419 0.001613 0.003900
Mitotic Spindle 0.000373 0.001120 0.001639 0.011924 0.000885 0.001830 0.001264 0.007121 0.000612 0.001549 0.001462 0.009470
None 0.006423 0.004435 0.001945 0.004324 0.008679 0.006696 0.003928 0.001571 0.007478 0.005798 0.002881 0.002917
Nuclear Periphery 0.001029 0.000833 0.001359 0.003137 0.000895 0.001710 0.001074 0.001966 0.000966 0.001362 0.001225 0.002539
Nuclear Periphery Foci 0.000246 0.000296 0.000270 0.001973 0.000301 0.000334 0.000625 0.001524 0.000272 0.000319 0.000437 0.001744
Nucleolus 0.010987 0.019855 0.018717 0.011809 0.016858 0.017385 0.017942 0.014130 0.013733 0.018366 0.018351 0.012995
Nucleus 0.941128 0.938568 0.931293 0.910796 0.954633 0.935062 0.932639 0.902396 0.947445 0.936454 0.931928 0.906504
Peroxisomes 0.000480 0.000478 0.000173 0.000403 0.000245 0.000594 0.000191 0.000197 0.000370 0.000548 0.000181 0.000297
Vacuole 0.002188 0.001511 0.001769 0.004482 0.000563 0.003874 0.001735 0.004964 0.001428 0.002936 0.001753 0.004728
Vacuole Periphery 0.000329 0.000373 0.000986 0.001799 0.000142 0.000776 0.001053 0.002306 0.000242 0.000616 0.001017 0.002058

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -9.86 -14.32 -11.99 -7.35 -6.05 -3.64 -26.63 -5.01 -4.55 -2.15 -8.64 -26.21 -8.86 -7.19 -4.23
Bud Neck -5.57 -18.47 -18.33 -13.30 -0.56 -8.76 -20.57 -22.58 -19.59 -7.62 -9.17 -27.23 -28.80 -23.93 -6.08
Bud Site -1.09 -1.38 -3.63 -2.17 -2.48 -5.09 -9.05 -5.61 -4.07 -4.13 -2.83 -3.65 -6.51 -4.79 -4.74
Cell Periphery 3.01 4.44 2.22 -0.08 -0.97 -2.54 1.65 1.90 4.10 0.54 2.36 4.64 2.59 0.94 -0.90
Cytoplasm 7.29 11.03 8.11 0.72 -3.49 -1.32 5.50 3.65 4.84 -2.01 5.16 12.27 8.99 4.03 -4.02
Cytoplasmic Foci 0.51 5.68 1.17 0.42 -2.18 -0.46 3.08 1.19 1.72 -1.91 -0.05 5.83 1.71 1.52 -2.91
Eisosomes -2.15 -6.55 -7.02 -4.69 -0.01 -3.16 -14.53 -8.85 -5.54 0.86 -3.18 -13.20 -11.00 -7.40 0.58
Endoplasmic Reticulum -2.55 2.40 2.08 7.42 -0.87 -8.69 -5.01 -8.32 3.58 0.70 -5.66 -0.73 -0.71 7.15 0.16
Endosome -0.80 2.47 -1.87 -0.50 -3.21 -4.33 -0.33 -2.84 -0.41 -2.58 -2.69 1.74 -3.26 -0.64 -4.10
Golgi -0.57 1.67 -1.18 -0.30 -2.91 0.06 0.59 -1.93 -2.07 -2.29 -0.31 1.44 -2.22 -2.08 -3.00
Lipid Particles 0.20 1.02 -0.09 -0.21 -0.89 -1.13 2.41 -0.15 0.32 -0.85 -1.33 2.43 -0.19 0.41 -1.08
Mitochondria -0.55 -0.36 -2.17 -1.89 -2.42 -1.84 -0.59 -3.49 -1.86 -3.89 -1.87 -0.66 -4.04 -2.43 -4.51
Mitotic Spindle -1.38 -2.58 -5.84 -5.42 -4.94 -1.23 -0.68 -4.56 -3.78 -4.22 -1.88 -2.36 -7.44 -6.50 -6.45
None 2.38 6.04 2.68 0.50 -3.38 1.49 4.12 6.42 5.81 3.19 2.06 6.78 6.75 4.78 -0.23
Nuclear Periphery 1.46 -1.06 -2.88 -3.25 -2.00 -4.51 -1.19 -4.15 -1.45 -2.76 -3.20 -1.51 -4.53 -3.25 -3.08
Nuclear Periphery Foci -0.65 -0.25 -2.25 -2.14 -2.19 -0.19 -0.80 -1.86 -1.77 -1.15 -0.49 -0.84 -2.92 -2.75 -2.39
Nucleolus -5.84 -6.49 -2.32 2.99 3.18 -0.28 -0.91 0.08 0.32 0.88 -4.31 -5.19 -1.60 2.14 2.81
Nucleus 0.65 3.56 7.43 6.79 5.06 4.85 6.85 12.03 8.08 7.44 3.76 7.12 13.61 10.39 8.84
Peroxisomes 0.03 1.40 0.63 1.20 -1.88 -2.10 1.41 0.98 2.76 -0.82 -1.17 1.75 0.92 2.84 -2.03
Vacuole 2.04 0.86 -4.64 -5.46 -4.91 -5.54 -3.67 -6.08 -2.24 -4.24 -3.88 -1.70 -7.48 -4.75 -6.47
Vacuole Periphery -0.45 -1.62 -2.38 -2.30 -0.52 -5.64 -2.09 -3.68 -2.20 -1.34 -4.44 -2.61 -4.32 -3.00 -1.37
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative tRNA acetyltransferase; RNA-binding protein required for the formation of the modified nucleoside N(4)-acetylcytidine in serine and leucine tRNAs but not required for the same modification in 18S rRNA; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages nucleus (95%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Tan1

Tan1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tan1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available