Standard name
Human Ortholog
Description High affinity methionine permease; integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Cytoplasm 0.05 0 0 0.07 0.05 0 0 0.1 0.21 0.21 0.34 0.45 0 0 0.05 0.14 0 – 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 – 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0.11 0.11 0.24 0 0.1 – 0 0 0 0 0.07 0.12
Golgi 0 0 0 0 0.05 0 0 0 0 0 0 0 0.08 0.08 0 0.11 0.15 – 0.06 0 0.08 0.14 0.12 0.15
Mitochondria 0.12 0.25 0.21 0 0.07 0.12 0.05 0.06 0.07 0.06 0.1 0.06 0.09 0.08 0 0 0.05 – 0.05 0 0.11 0.08 0.11 0.13
Nucleus 0.15 0.14 0.12 0.2 0.12 0.23 0.27 0.17 0.17 0.18 0.09 0.1 0.07 0.07 0.08 0.23 0.25 – 0.06 0.05 0 0.05 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Nucleolus 0.11 0.13 0.11 0.06 0 0.07 0.05 0.06 0 0 0 0 0.09 0.09 0.1 0.12 0.2 – 0.06 0 0.05 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.09 0.18 0 0 – 0 0 0 0 0 0
Vac/Vac Membrane 0.68 0.66 0.69 0.71 0.77 0.67 0.66 0.71 0.67 0.68 0.61 0.51 0.67 0.68 0.55 0.62 0.5 – 0.71 0.79 0.67 0.62 0.59 0.49
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 2 1 0 3 4 2 1 2 5 4 3 4 0 0 – 0 1 1 2 1 6
Bud 1 0 0 1 0 1 0 3 4 5 7 9 3 3 5 0 0 – 1 0 1 0 1 3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 1 0 0 1 2 2 1 0 0 1 0 0 – – – – – – –
Cell Periphery 0 0 0 2 0 0 0 1 1 0 1 2 1 1 1 0 0 – 0 0 0 0 0 0
Cytoplasm 14 0 11 21 22 8 29 77 111 131 112 250 17 17 33 8 0 – 2 0 0 0 0 2
Endoplasmic Reticulum 0 0 1 4 1 2 4 4 5 6 2 4 0 0 0 2 1 – 0 0 0 0 0 2
Endosome 0 0 2 0 3 14 25 29 18 27 8 23 76 75 165 1 2 – 8 3 6 9 24 44
Golgi 11 1 3 6 22 1 6 2 3 1 0 1 53 54 22 6 3 – 19 3 27 30 40 57
Mitochondria 31 27 61 8 30 44 35 50 35 36 34 34 60 60 28 2 1 – 14 5 35 17 35 48
Nucleus 40 15 33 63 50 86 173 132 90 112 30 54 48 48 58 13 5 – 18 6 13 9 6 5
Nuclear Periphery 3 1 0 0 1 3 4 2 0 0 2 1 3 5 2 0 0 – 2 1 3 2 7 9
Nucleolus 28 14 31 17 18 26 33 48 18 24 8 19 65 65 69 7 4 – 20 5 15 6 8 4
Peroxisomes 0 0 0 0 2 3 4 8 5 0 3 2 21 23 28 0 0 – 0 0 1 0 2 3
SpindlePole 0 0 0 0 2 6 20 19 14 15 11 18 62 61 123 0 0 – 0 0 1 1 2 2
Vac/Vac Membrane 177 72 196 220 321 247 431 558 346 420 204 283 464 480 385 35 10 – 223 104 220 134 191 183
Unique Cell Count 262 109 285 308 417 368 649 783 519 619 334 560 697 710 697 56 20 316 132 330 216 324 376
Labelled Cell Count 305 130 338 344 473 442 767 937 653 780 426 706 877 895 924 74 26 316 132 330 216 324 376


Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 44.8 44.1 43.9 44.2 39.4 27.9 23.5 19.8 17.8 15.8 13.5 13.4 15.4 15.4 11.3 47.9 38.0 – 34.4 29.1 27.6
Std Deviation (1e-4) 19.5 18.1 18.2 17.8 18.5 18.1 16.2 15.0 13.4 13.4 11.7 10.9 6.0 6.0 3.9 29.4 20.0 – 15.0 12.9 11.8
Intensity Change (Log2) – – – 0.01 -0.15 -0.65 -0.9 -1.15 -1.3 -1.47 -1.7 -1.71 -1.51 -1.51 -1.96 0.13 -0.21 – -0.35 -0.59 -0.67

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000204060WT3HU80HU120HU1600204060WT3rpd3Δ_1rpd3Δ_20204060WT1AF100AF140AF1800204060
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Cytoplasm 1.6 0.9 -1.3 0.4 3.1 6.6 6.6 9.2 12.1 -1.2 -1.3 0.6 0 0 –
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Endosome 0 0 2.5 2.6 2.6 2.4 2.9 0 2.8 5.4 5.3 8.7 0 0 –
Golgi 0 3.0 0 0 0 0 0 0 0 4.0 4.0 1.9 0 0 –
Mitochondria -7.1 -5.5 -3.3 -7.4 -7.1 -6.1 -7.0 -3.9 -6.7 -5.5 -5.7 -8.6 -3.1 0 –
Nucleus 2.9 0.2 3.9 5.1 2.1 2.2 2.5 -1.1 -0.9 -2.4 -2.5 -1.6 2.3 0 –
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Nucleolus -2.4 -3.4 -1.7 -3.2 -2.6 -4.2 -4.1 -4.3 -4.4 -0.7 -0.8 -0.5 0.4 0 –
Peroxisomes 0 0 0 0 0 0 0 0 0 3.0 3.1 3.4 0 0 –
SpindlePole 0 0 0 3.0 2.7 0 0 3.1 3.1 5.2 5.1 7.6 0 0 –
Vacuole 0.7 2.4 -0.4 -0.7 0.8 -0.6 -0.3 -2.0 -5.1 -0.7 -0.4 -3.9 -0.9 -1.7 –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 37.9565 63.9243 58.6418 45.5666 56.4469 61.1304 43.2528 58.1299 57.6054 50.6654 53.5988 61.877 50.1976 75.6191 67.0112 62.4065 65.5332 67.9858
Actin 0.0052 0 0 0 0 0 0.0008 0.0001 0.0001 0.0001 0 0.0001 0.0018 0 0.0001 0 0 0
Bud 0.0002 0.0001 0.0001 0.0011 0.0005 0.0001 0.0003 0.0004 0.0002 0.0004 0.0001 0.0001 0.0004 0 0.0001 0.0001 0.0003 0
Bud Neck 0.0004 0.0004 0.0004 0.001 0.0004 0.0002 0.0004 0.0011 0.0003 0.0046 0.0002 0.0005 0.0003 0.0001 0.0013 0.0004 0.0003 0.0002
Bud Periphery 0.0005 0.0003 0.0003 0.0007 0.0011 0.0003 0.0005 0.0005 0.0003 0.0011 0.0006 0.0005 0.0011 0.0002 0.0003 0.0005 0.0013 0.0002
Bud Site 0.0008 0.0002 0.0001 0.0004 0.0002 0 0.0006 0.0016 0.0005 0.0011 0.0001 0.0001 0.0005 0 0.0002 0.0003 0.0003 0.0001
Cell Periphery 0.0391 0.0378 0.0329 0.0531 0.074 0.0397 0.0727 0.0235 0.0283 0.0374 0.0919 0.0538 0.0301 0.0213 0.0313 0.0428 0.0423 0.0335
Cytoplasm 0.0027 0.0002 0.0001 0.0201 0.0002 0.0001 0.0002 0.0001 0 0.0001 0 0.0001 0.0008 0 0 0 0.0001 0
Cytoplasmic Foci 0.0058 0.0004 0.0003 0.0327 0.0003 0.0001 0.0863 0.0006 0.0004 0.0005 0.0002 0.0006 0.001 0.0001 0.0004 0.0007 0.0059 0.0002
Eisosomes 0.0001 0 0 0 0 0 0.0004 0 0.0001 0.0001 0 0 0.0001 0 0.0001 0 0.0002 0
Endoplasmic Reticulum 0.0012 0.0001 0.0001 0.0002 0.0001 0.0001 0 0 0 0.0001 0 0.0001 0.0011 0.0001 0 0 0.0001 0
Endosome 0.0097 0.0012 0.0026 0.0021 0.0019 0.0014 0.0013 0.0015 0.0011 0.0021 0.0007 0.0022 0.0062 0.0009 0.0015 0.0013 0.0012 0.0012
Golgi 0.0018 0.0001 0.0004 0.0001 0.0002 0.0001 0.001 0.0003 0.0002 0.0004 0.0001 0.001 0.001 0.0001 0.0006 0.0003 0.0002 0.0003
Lipid Particles 0.0221 0.0046 0.0177 0.007 0.005 0.0061 0.1147 0.0145 0.027 0.0245 0.0464 0.0508 0.0569 0.0216 0.036 0.0434 0.0313 0.0309
Mitochondria 0.0393 0.0071 0.0161 0.003 0.0047 0.0043 0.1453 0.0304 0.1688 0.1802 0.0182 0.0447 0.1174 0.0315 0.1462 0.0414 0.0254 0.0324
None 0.003 0 0 0.0187 0 0 0.0026 0.0001 0 0 0 0 0.0017 0 0 0 0.0005 0
Nuclear Periphery 0.0107 0.0016 0.0006 0.0011 0.0003 0.0106 0.0001 0.0013 0.0003 0.0009 0.0002 0.0019 0.004 0.0007 0.0007 0.0002 0.0004 0.0013
Nucleolus 0.084 0.0281 0.0299 0.0862 0.0343 0.0309 0.0562 0.1478 0.1252 0.1082 0.1144 0.0991 0.1068 0.0242 0.071 0.1051 0.1625 0.0581
Nucleus 0.0116 0.0095 0.0108 0.0163 0.0071 0.0093 0.0057 0.0113 0.007 0.0104 0.0153 0.0068 0.0092 0.0029 0.0058 0.0085 0.0114 0.0067
Peroxisomes 0.0015 0.0001 0.0002 0.0002 0.0002 0.0001 0.0049 0.001 0.0017 0.0021 0.0003 0.0009 0.001 0.0001 0.0012 0.0017 0.0009 0.0004
Punctate Nuclear 0.0044 0 0 0.0049 0 0 0.001 0 0 0 0 0 0.0004 0 0 0 0.0001 0
Vacuole 0.2914 0.3952 0.3264 0.3845 0.4715 0.3463 0.2451 0.183 0.1984 0.2341 0.2959 0.2737 0.1808 0.2898 0.2066 0.3296 0.2801 0.2511
Vacuole Periphery 0.4647 0.513 0.5611 0.3667 0.3979 0.5504 0.2597 0.5809 0.4399 0.3917 0.4154 0.4629 0.4771 0.6065 0.4963 0.4234 0.4353 0.5833

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 53.0913 76.6228 154.8729 212.2556 88.7394 70.3231 91.2046 124.6747 190.8582 98.1449
Translational Efficiency 1.1173 1.026 1.0388 1.1479 0.9347 0.9374 0.9439 1.0107 0.9571 0.8286

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
84 963 1063 928 1654 1367 2207 1309 1738 2330 3270 2237

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1717.12 3247.58 1483.88 1415.85 2271.07 2666.03 1446.97 1500.43 2244.30 2906.39 1458.97 1465.34
Standard Deviation 633.70 1186.55 305.87 332.28 884.00 859.71 310.03 361.45 881.59 1047.63 309.17 352.12
Intensity Change Log 2 — 0.919374 -0.210616 -0.278322 — 0.231321 -0.650337 -0.597996 — 0.568305 -0.444415 -0.451605

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000122 0.000129 0.000122 0.000211 0.000125 0.000159 0.000242 0.000208 0.000125 0.000147 0.000203 0.000209
Bud Neck 0.004724 0.001912 0.001956 0.006171 0.001653 0.002793 0.004833 0.002928 0.001801 0.002429 0.003897 0.004273
Bud Site 0.011430 0.001028 0.003849 0.016103 0.002453 0.002589 0.013755 0.013065 0.002887 0.001944 0.010535 0.014325
Cell Periphery 0.001072 0.009599 0.001213 0.001386 0.025115 0.012620 0.004558 0.002728 0.023953 0.011371 0.003471 0.002171
Cytoplasm 0.007569 0.000259 0.000749 0.001612 0.000240 0.000216 0.000840 0.002370 0.000595 0.000234 0.000810 0.002056
Cytoplasmic Foci 0.018717 0.000619 0.011064 0.005870 0.001426 0.001422 0.007127 0.007400 0.002262 0.001090 0.008407 0.006765
Eisosomes 0.000034 0.004120 0.000039 0.000039 0.001643 0.006862 0.000082 0.000028 0.001565 0.005729 0.000068 0.000032
Endoplasmic Reticulum 0.000584 0.000506 0.001054 0.001183 0.001102 0.000861 0.002329 0.001281 0.001077 0.000715 0.001915 0.001240
Endosome 0.038469 0.000430 0.079618 0.051072 0.002689 0.002085 0.131110 0.047738 0.004419 0.001401 0.114371 0.049121
Golgi 0.030503 0.000212 0.034186 0.028185 0.003550 0.000366 0.035322 0.040866 0.004852 0.000303 0.034953 0.035605
Lipid Particles 0.002067 0.002368 0.008614 0.002188 0.002734 0.002065 0.004827 0.001529 0.002702 0.002190 0.006058 0.001802
Mitochondria 0.016018 0.005016 0.004320 0.005787 0.011782 0.008521 0.003330 0.007434 0.011986 0.007073 0.003652 0.006751
Mitotic Spindle 0.005007 0.000015 0.000850 0.005200 0.000027 0.000325 0.000945 0.002910 0.000268 0.000197 0.000914 0.003860
None 0.000163 0.000492 0.000128 0.000171 0.001115 0.000449 0.000090 0.000188 0.001069 0.000467 0.000103 0.000181
Nuclear Periphery 0.002203 0.000368 0.001223 0.002190 0.000179 0.000634 0.000779 0.000890 0.000277 0.000524 0.000924 0.001429
Nuclear Periphery Foci 0.002622 0.000574 0.004688 0.003936 0.000445 0.001131 0.002339 0.001713 0.000550 0.000901 0.003103 0.002635
Nucleolus 0.001945 0.009039 0.001945 0.002833 0.003980 0.011916 0.001012 0.000694 0.003882 0.010727 0.001315 0.001582
Nucleus 0.002329 0.002630 0.000675 0.001752 0.001089 0.002739 0.000415 0.000588 0.001149 0.002694 0.000500 0.001071
Peroxisomes 0.002038 0.000185 0.000523 0.000822 0.000304 0.000471 0.000472 0.000480 0.000388 0.000353 0.000489 0.000622
Vacuole 0.590291 0.834750 0.642956 0.651252 0.760367 0.867926 0.655355 0.651493 0.752147 0.854214 0.651324 0.651393
Vacuole Periphery 0.262094 0.125749 0.200227 0.212038 0.177982 0.073848 0.130238 0.213470 0.182047 0.095299 0.152990 0.212876

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.26 0.21 -0.99 -1.40 -1.11 -1.04 -1.85 -1.56 -0.86 0.37 -0.92 -1.69 -2.11 -1.50 -0.12
Bud Neck 2.36 2.32 -0.77 -5.13 -5.11 -3.32 -7.05 -3.59 -0.50 3.26 -2.37 -6.29 -5.99 -4.36 -0.98
Bud Site 2.11 1.67 -0.21 -7.52 -5.93 -0.21 -10.76 -7.77 -7.35 0.04 2.08 -9.01 -9.34 -10.51 -3.13
Cell Periphery -6.31 -0.26 -0.57 6.41 -0.63 5.99 11.62 12.94 7.91 3.04 6.82 12.37 13.32 10.16 3.20
Cytoplasm 2.13 2.06 1.82 -2.98 -2.42 0.20 -3.53 -3.68 -3.71 -2.79 1.77 0.08 -3.10 -4.72 -3.60
Cytoplasmic Foci 3.26 1.31 2.28 -7.14 3.29 -0.10 -7.65 -5.77 -5.68 -0.19 2.89 -8.26 -6.02 -8.25 1.76
Eisosomes -8.94 -0.43 -0.49 8.93 -0.11 -7.82 9.47 9.84 10.57 3.30 -9.20 9.55 9.80 13.41 3.13
Endoplasmic Reticulum 0.40 -2.42 -2.92 -5.60 -0.89 1.53 -3.84 -0.94 -1.86 2.93 3.35 -3.76 -1.24 -3.72 2.81
Endosome 4.98 -4.76 -1.59 -14.43 4.97 0.85 -31.86 -15.10 -15.22 16.75 4.44 -34.71 -19.17 -20.93 16.97
Golgi 2.90 -0.41 0.17 -9.41 1.50 4.83 -15.64 -11.52 -12.77 -1.46 5.61 -16.92 -12.96 -15.82 -0.18
Lipid Particles -0.30 -3.82 -0.13 0.33 4.26 2.33 -3.47 4.17 1.53 5.19 2.16 -5.29 3.42 1.34 6.51
Mitochondria 1.03 1.09 0.95 -0.50 -0.94 1.63 5.40 1.99 0.54 -2.57 2.78 5.25 2.80 0.24 -2.79
Mitotic Spindle 1.28 1.17 0.67 -3.32 -2.68 -1.05 -3.79 -3.55 -3.04 -2.33 0.84 -0.74 -3.60 -4.48 -3.54
None -4.01 1.08 0.07 4.32 -1.28 1.74 2.70 2.40 4.27 -2.17 1.65 2.67 2.43 6.07 -2.64
Nuclear Periphery 2.02 1.08 0.01 -3.25 -1.69 -3.22 -4.65 -3.29 -0.99 -0.41 -2.40 -5.82 -4.33 -3.26 -1.79
Nuclear Periphery Foci 2.14 -0.85 -0.49 -3.99 0.48 -3.48 -5.84 -2.23 -0.97 0.97 -2.32 -6.24 -4.24 -3.52 0.68
Nucleolus -4.41 -0.05 -1.12 3.75 -1.27 -6.12 7.46 8.54 9.01 2.23 -6.70 6.55 4.98 9.15 -0.96
Nucleus -0.16 1.49 0.50 0.78 -2.50 -2.58 2.65 1.32 3.35 -1.12 -2.59 2.63 -0.04 2.60 -2.83
Peroxisomes 2.86 2.30 1.77 -3.67 -1.52 -0.90 -1.71 -1.48 -0.05 -0.06 0.25 -1.09 -2.00 -2.01 -1.28
Vacuole -8.73 -2.11 -2.36 18.02 -0.69 -14.73 13.84 12.21 25.31 0.50 -15.20 14.42 13.29 30.94 0.09
Vacuole Periphery 5.04 2.15 1.72 -9.84 -1.28 17.09 8.16 -4.64 -21.26 -13.06 14.68 5.10 -4.67 -22.15 -11.75
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description High affinity methionine permease; integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake
Localization
Cell Percentages vacuole (28%), nucleus (2%), mixed (54%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Mup1

Mup1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mup1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available